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Anatomy & PhysiologyAnatomy & Physiology
for the EP professionalfor the EP professional
Part I
ObjectivesObjectives
• Describe the anatomic structures of the chest
• Identify the neck, chest and femoral
vasculature.
• Describe vascular access and complications.
• Identify cardiac chambers, valves, arteries &
veins
• Identify blood supply to the conduction system
• Describe the flow of blood through the heart
Thoracic CavityThoracic CavityThoracic AnatomyThoracic Anatomy
Thoracic AnatomyThoracic Anatomy
Thoracic VasculatureThoracic Vasculature
Thoracic VeinsThoracic Veins
Thoracic CageThoracic Cage
• Houses the right & left Lung
– Right lung has 3 lobes
– Left Lung has 2 lobes
• Heart
• All structures are enclosed by the
parietal pleura
Venous landmarks of upperVenous landmarks of upper
chestchest
Chest Venous accessChest Venous access
• Most often axillary access for device
implants.
• Internal jugular vein for T-pacer
placement
• Subclavian no longer the access of
choice d/t pneumothorax & subclavian
crush
• Femoral vein for studies
Chest venous accessChest venous access
• Axillary vein is lateral to the apex of the
left lobe of the lung
• Less complications of pneumothorax
• Most perform a venogram prior to
accessing the vein for pacemaker lead
implant
• Majority of cardiac devices are
implanted in the left pectoral region of
chest
Venogram using
the antecubital or
median basilic
vein allows
visualization of
subclavian,
axillary and
innominate veins
AxillaryAxillary
AnatomyAnatomy
Complications- chestComplications- chest
accessaccess
• Subclavian crush –
– Lead positioned via the subclavian vein.
– Subclavian vein lies between the clavicle
and the 1st
rib.
– Deterioration of the insulation material and
the wires leads to failure of the
pacemaker/ICD leads.
ComplicationsComplications
• Post device implant swelling at the
pectoral site may be as a result of
– Generally “wet” site due to A/C status
– Inadvertent arterial nick
• Pressure at site may result in
hemostasis
– If extreme, re-open and cauterize
– Often, device site pain relieved with
elevation to 30 degrees and ice compress.
ComplicationsComplications
• Pneumothorax
– Because the subclavian vein is situated
between the clavicle and the first rib, often
times the needle must be bent to access
vein.
– Lung extends above the clavicle
approximately 1 inch
– Angle of the needle to be at least 20-30º
Cross section of theCross section of the
Clavicle & 1Clavicle & 1stst
RibRib
Internal JugularInternal Jugular
accessaccess
• Was used for the coronary sinus wire
insertion
• Access of choice for T -Pacers
IJ ComplicationsIJ Complications
• Difficult puncture for many due to
location of vein
• Arterial puncture complication
– Difficult to obtain hemostasis if A/C levels
are high
IJ AnatomyIJ Anatomy
Femoral accessFemoral access
• Most often used for all EP studies
• As many as 4 sheaths in the veins at once
(Can have 3 sheaths on one side)
• Occasionally an arterial sheath is inserted
during some studies
• All venous lines must be connected to fluid
and at KVO rate
• Arterial lines must be connected to pressure
during and after the case, until the line is
D/C’d
Femoral AnatomyFemoral Anatomy
Femoral ArterialFemoral Arterial
ComplicationsComplications
• Hematoma is number one complication of
arterial stick
Vascular ComplicationsVascular Complications
• Treatment – Hematoma
– Manual pressure at site
• DO NOT try to “squeeze out” blood
• Goal is hemostasis
– Pressure dressing
– Needle aspiration
– Surgical evacuation
• May require surgical repair of artery/vein
Femoral ComplicationsFemoral Complications
• Arterial
– Hematoma
• May rapidly increase in size
– Bleeding
• Lack of hemostasis
– Pseudoaneurysm
• a.k.a. “false aneurysm”
• Hematoma outside of and adjacent
to artery
• Communication with arterial lumen
• Treat with compression or surgery
Femoral ComplicationsFemoral Complications
• Arterial complications (cont’d)
AV fistula
Inadvertent cannulation of artery thru the
vein
May require surgical repair
Retroperitoneal bleed
Damage to posterior artery
– Blood collects in peritoneal cavity
– Flank/lower back pain
– Requires surgical repair
– Usually emergent repair
Femoral ComplicationsFemoral Complications
• Venous
– Hematoma
• Collection of blood underneath skin
• Manual compression to stop bleeding
• DO NOT try to “squeeze out”
• Mark the hematoma edges with sharpie
pen and time the marking
• Bleeding
– Manual compression at site of
bleeding
Gross Cardiac A & PGross Cardiac A & P
Location of the HeartLocation of the Heart
• Lies roughly in
the center of
thoracic cavity
• Attached to
thorax via the
great vessels
Location of the HeartLocation of the Heart
• Apex (bottom)
– Formed by tip of left ventricle
– Points anterior and inferior
• Base (top)
– Approximately 2nd intercostal space
– Angle of Louis
• Anterior surface
– Primarily right ventricle
• Inferior (diaphragmatic) surface
– Right and left ventricles, predominantly left
Size and Shape of theSize and Shape of the
HeartHeart
• Cone-shaped
• Adult heart size:
– ~5 inches (12 cm) long
– ~3.5 inches (9 cm)
wide
– ~2.5 inches (6 cm)
thick
– About the size of a
man’s fist
Size and Shape of theSize and Shape of the
HeartHeart
Heart ChambersHeart Chambers
• Four chambers
• Two upper
– Right atrium
– Left atrium
• Two lower
– Right ventricle
– Left ventricle
AtriaAtria
Thin-walled
Low-pressure
Separated by
interatrial
septum
“Atrial kick”
Due to atrial
contraction
25-30% of CO
VentriclesVentricles
• Right ventricle
– Pumps venous blood to lungs
– Low pressure chamber
• Left ventricle
– Pumps arterial blood to body
– High pressure chamber
• Chambers separated by
interventricular septum
• The Fibrous Skeleton of the heart
consists of:
– AV Valves (semi-lunar)
• Tricuspid valve separates the
right atrium from the right
ventricle
• Mitral valve separates the left
atrium from the left ventricle
• Fibrous skeleton is electrically inert
ValvesValves
Valvular orientationValvular orientation
Valvular orientationValvular orientation
Accessory Pathway Locations based on Valve LandmarksAccessory Pathway Locations based on Valve Landmarks
ValvesValves
• Pulmonic Valve
Prevents blood from flowing
backwards into the right
ventricle
• Aortic Valve
Prevents blood from flowing
backwards into the left ventricle.
Valves cont’dValves cont’d
Normal Valve Areas Critical
Aortic 2.5 – 3.5 cm2 .7cm2
Pulmonic 4-6 cm2
Mitral 2.5-3.5 cm2 <1.0 cm2
Tricuspid 8-10 cm2
Anatomy and PhysiologyAnatomy and Physiology
• Coronary Blood Supply
– RCA
– Left Main
• LAD
• LCX
Coronary VasculatureCoronary Vasculature
Coronary Vasculature – Inferior viewCoronary Vasculature – Inferior view
CoronaryCoronary
ArteriesArteries
Right Coronary ArteryRight Coronary Artery
• Originates from the right coronary cusp
of the aorta
• Passes along the atrioventricular sulcus
between the right atria and ventricle
• Marginal branch of the RCA supplies the
RA and RV
Right Coronary ArteryRight Coronary Artery
• The coronary artery that gives rise to the
posterior descending artery (PDA) is
known as the “dominant” coronary artery
and most often is the RCA
• The PDA supplies blood to the posterior
surface of both walls of the ventricles.
• PDA supplies the posterior third of the
interventricular septum.
• In 50-60% a branch of the RCA supplies
the SA node.
• In 85-90% of hearts the RCA also
branches into the AV nodal artery.
RCA cont’d
Left Coronary ArteryLeft Coronary Artery
• Arises from the left coronary cusp of
the aorta.
• Consists of the left main coronary
artery.
• The left main artery bifurcates into the
left circumflex artery (LCX) and the left
anterior descending artery (LAD).
Left Coronary SystemLeft Coronary System
• LAD travels along anterior
interventricular sulcus and supplies
blood to the anterior surface of both
ventricles.
• LAD branches include the diagonal
and septal arteries.
Left Coronary SystemLeft Coronary System
• LCX passes along the left atrioventricular
sulcus between the left atria and ventricle.
• Supplies the lateral wall of the LV
• May also supply the inferior portion of the
LV.
• LCX artery supplies the SA node in 40-
60%.
• LCX supplies the AV node in 10-15%.
Blood SupplyBlood Supply
• The SA and AV nodes are supplied by
the RCA and LCX.
• The bundle branches are supplied by
the LAD.
– Thus an occluded RCA may cause nodal
dysfunction.
– An occluded LAD may cause a BBB.
– The possibility of reentrant arrhythmias is
present with any infarct.
CirculationCirculation
• Blood in the atrium is ejected into the
ventricles during atrial contraction.
• Passive filling of the ventricles occurs.
• Ventricles eject blood thru the
pulmonary artery to the alveoli for
oxygenation and thru the aorta for
systemic oxygenation.
• Coronary artery perfusion occurs
during diastole.
ReferencesReferences
• Netter, F H (1987) The CIBA collection of medical Illustrations.
Volume 5 The heart. Colorpress, New York NY
• Mazgalev, T.N., Tchou, P.J. (2000) Atrial AV Nodal
Electrophysiology; A view from the millennium. Futura, Armonk,
NY
• Podrid, P.J., Kowey, P.R. (2001) Cardiac Arrhythmia,
Mechanisms, Diagnosis & Management, 2nd
Ed. Lippincott,
Williams & Wilkins. Philadelphia PA
• Anderson, R.H. (2000) Electrical Anatomy of the Atrial
Chambers. Medtronic USA
• Anderson R.H., Ho, S.W. ( n.d.) The Anatomy of the
Atrioventricular Node. Article review by Sechler, D.A., RN

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Anatomy & physiology for the EP professional part I 8.4.14

  • 1. Anatomy & PhysiologyAnatomy & Physiology for the EP professionalfor the EP professional Part I
  • 2. ObjectivesObjectives • Describe the anatomic structures of the chest • Identify the neck, chest and femoral vasculature. • Describe vascular access and complications. • Identify cardiac chambers, valves, arteries & veins • Identify blood supply to the conduction system • Describe the flow of blood through the heart
  • 3. Thoracic CavityThoracic CavityThoracic AnatomyThoracic Anatomy
  • 7. Thoracic CageThoracic Cage • Houses the right & left Lung – Right lung has 3 lobes – Left Lung has 2 lobes • Heart • All structures are enclosed by the parietal pleura
  • 8. Venous landmarks of upperVenous landmarks of upper chestchest
  • 9. Chest Venous accessChest Venous access • Most often axillary access for device implants. • Internal jugular vein for T-pacer placement • Subclavian no longer the access of choice d/t pneumothorax & subclavian crush • Femoral vein for studies
  • 10. Chest venous accessChest venous access • Axillary vein is lateral to the apex of the left lobe of the lung • Less complications of pneumothorax • Most perform a venogram prior to accessing the vein for pacemaker lead implant • Majority of cardiac devices are implanted in the left pectoral region of chest
  • 11. Venogram using the antecubital or median basilic vein allows visualization of subclavian, axillary and innominate veins AxillaryAxillary AnatomyAnatomy
  • 12. Complications- chestComplications- chest accessaccess • Subclavian crush – – Lead positioned via the subclavian vein. – Subclavian vein lies between the clavicle and the 1st rib. – Deterioration of the insulation material and the wires leads to failure of the pacemaker/ICD leads.
  • 13. ComplicationsComplications • Post device implant swelling at the pectoral site may be as a result of – Generally “wet” site due to A/C status – Inadvertent arterial nick • Pressure at site may result in hemostasis – If extreme, re-open and cauterize – Often, device site pain relieved with elevation to 30 degrees and ice compress.
  • 14. ComplicationsComplications • Pneumothorax – Because the subclavian vein is situated between the clavicle and the first rib, often times the needle must be bent to access vein. – Lung extends above the clavicle approximately 1 inch – Angle of the needle to be at least 20-30º
  • 15. Cross section of theCross section of the Clavicle & 1Clavicle & 1stst RibRib
  • 16. Internal JugularInternal Jugular accessaccess • Was used for the coronary sinus wire insertion • Access of choice for T -Pacers
  • 17. IJ ComplicationsIJ Complications • Difficult puncture for many due to location of vein • Arterial puncture complication – Difficult to obtain hemostasis if A/C levels are high
  • 19. Femoral accessFemoral access • Most often used for all EP studies • As many as 4 sheaths in the veins at once (Can have 3 sheaths on one side) • Occasionally an arterial sheath is inserted during some studies • All venous lines must be connected to fluid and at KVO rate • Arterial lines must be connected to pressure during and after the case, until the line is D/C’d
  • 21. Femoral ArterialFemoral Arterial ComplicationsComplications • Hematoma is number one complication of arterial stick
  • 22. Vascular ComplicationsVascular Complications • Treatment – Hematoma – Manual pressure at site • DO NOT try to “squeeze out” blood • Goal is hemostasis – Pressure dressing – Needle aspiration – Surgical evacuation • May require surgical repair of artery/vein
  • 23. Femoral ComplicationsFemoral Complications • Arterial – Hematoma • May rapidly increase in size – Bleeding • Lack of hemostasis – Pseudoaneurysm • a.k.a. “false aneurysm” • Hematoma outside of and adjacent to artery • Communication with arterial lumen • Treat with compression or surgery
  • 24. Femoral ComplicationsFemoral Complications • Arterial complications (cont’d) AV fistula Inadvertent cannulation of artery thru the vein May require surgical repair Retroperitoneal bleed Damage to posterior artery – Blood collects in peritoneal cavity – Flank/lower back pain – Requires surgical repair – Usually emergent repair
  • 25. Femoral ComplicationsFemoral Complications • Venous – Hematoma • Collection of blood underneath skin • Manual compression to stop bleeding • DO NOT try to “squeeze out” • Mark the hematoma edges with sharpie pen and time the marking • Bleeding – Manual compression at site of bleeding
  • 26. Gross Cardiac A & PGross Cardiac A & P
  • 27. Location of the HeartLocation of the Heart • Lies roughly in the center of thoracic cavity • Attached to thorax via the great vessels
  • 28. Location of the HeartLocation of the Heart • Apex (bottom) – Formed by tip of left ventricle – Points anterior and inferior • Base (top) – Approximately 2nd intercostal space – Angle of Louis • Anterior surface – Primarily right ventricle • Inferior (diaphragmatic) surface – Right and left ventricles, predominantly left
  • 29. Size and Shape of theSize and Shape of the HeartHeart • Cone-shaped • Adult heart size: – ~5 inches (12 cm) long – ~3.5 inches (9 cm) wide – ~2.5 inches (6 cm) thick – About the size of a man’s fist
  • 30. Size and Shape of theSize and Shape of the HeartHeart
  • 31. Heart ChambersHeart Chambers • Four chambers • Two upper – Right atrium – Left atrium • Two lower – Right ventricle – Left ventricle
  • 33. VentriclesVentricles • Right ventricle – Pumps venous blood to lungs – Low pressure chamber • Left ventricle – Pumps arterial blood to body – High pressure chamber • Chambers separated by interventricular septum
  • 34. • The Fibrous Skeleton of the heart consists of: – AV Valves (semi-lunar) • Tricuspid valve separates the right atrium from the right ventricle • Mitral valve separates the left atrium from the left ventricle • Fibrous skeleton is electrically inert ValvesValves
  • 37. Accessory Pathway Locations based on Valve LandmarksAccessory Pathway Locations based on Valve Landmarks
  • 38. ValvesValves • Pulmonic Valve Prevents blood from flowing backwards into the right ventricle • Aortic Valve Prevents blood from flowing backwards into the left ventricle.
  • 39. Valves cont’dValves cont’d Normal Valve Areas Critical Aortic 2.5 – 3.5 cm2 .7cm2 Pulmonic 4-6 cm2 Mitral 2.5-3.5 cm2 <1.0 cm2 Tricuspid 8-10 cm2
  • 40. Anatomy and PhysiologyAnatomy and Physiology • Coronary Blood Supply – RCA – Left Main • LAD • LCX
  • 42. Coronary Vasculature – Inferior viewCoronary Vasculature – Inferior view
  • 44. Right Coronary ArteryRight Coronary Artery • Originates from the right coronary cusp of the aorta • Passes along the atrioventricular sulcus between the right atria and ventricle • Marginal branch of the RCA supplies the RA and RV
  • 45. Right Coronary ArteryRight Coronary Artery • The coronary artery that gives rise to the posterior descending artery (PDA) is known as the “dominant” coronary artery and most often is the RCA • The PDA supplies blood to the posterior surface of both walls of the ventricles.
  • 46. • PDA supplies the posterior third of the interventricular septum. • In 50-60% a branch of the RCA supplies the SA node. • In 85-90% of hearts the RCA also branches into the AV nodal artery. RCA cont’d
  • 47. Left Coronary ArteryLeft Coronary Artery • Arises from the left coronary cusp of the aorta. • Consists of the left main coronary artery. • The left main artery bifurcates into the left circumflex artery (LCX) and the left anterior descending artery (LAD).
  • 48. Left Coronary SystemLeft Coronary System • LAD travels along anterior interventricular sulcus and supplies blood to the anterior surface of both ventricles. • LAD branches include the diagonal and septal arteries.
  • 49. Left Coronary SystemLeft Coronary System • LCX passes along the left atrioventricular sulcus between the left atria and ventricle. • Supplies the lateral wall of the LV • May also supply the inferior portion of the LV. • LCX artery supplies the SA node in 40- 60%. • LCX supplies the AV node in 10-15%.
  • 50. Blood SupplyBlood Supply • The SA and AV nodes are supplied by the RCA and LCX. • The bundle branches are supplied by the LAD. – Thus an occluded RCA may cause nodal dysfunction. – An occluded LAD may cause a BBB. – The possibility of reentrant arrhythmias is present with any infarct.
  • 51. CirculationCirculation • Blood in the atrium is ejected into the ventricles during atrial contraction. • Passive filling of the ventricles occurs. • Ventricles eject blood thru the pulmonary artery to the alveoli for oxygenation and thru the aorta for systemic oxygenation. • Coronary artery perfusion occurs during diastole.
  • 52. ReferencesReferences • Netter, F H (1987) The CIBA collection of medical Illustrations. Volume 5 The heart. Colorpress, New York NY • Mazgalev, T.N., Tchou, P.J. (2000) Atrial AV Nodal Electrophysiology; A view from the millennium. Futura, Armonk, NY • Podrid, P.J., Kowey, P.R. (2001) Cardiac Arrhythmia, Mechanisms, Diagnosis & Management, 2nd Ed. Lippincott, Williams & Wilkins. Philadelphia PA • Anderson, R.H. (2000) Electrical Anatomy of the Atrial Chambers. Medtronic USA • Anderson R.H., Ho, S.W. ( n.d.) The Anatomy of the Atrioventricular Node. Article review by Sechler, D.A., RN

Editor's Notes

  1. The heart is a hollow muscular organ that lies in the middle of the thoracic cavity (mediastinum) behind the sternum, between the lungs, and just above the diaphragm. It is surrounded by a protective sac (pericardium) and is attached to the thorax through the great vessels (pulmonary arteries and veins, aorta, superior and inferior vena cavae).
  2. The apex (bottom) of the heart is formed by the tip of the left ventricle. It is positioned just above the diaphragm to the left in an anterior position, at the 5th intercostal space, midclavicular line. The base (top) of the heart is approximately at the level of the 2nd intercostal space. The anterior surface of the heart consists primarily of the right ventricle. The inferior (diaphragmatic) surface is formed by the right and left ventricles (predominantly the left). Contraction of the left ventricle normally produces a visible and palpable impulse at the apex of the heart (apical impulse). This occurs because as the left ventricle contracts, it rotates forward, causing the apex of the left ventricle to hit the chest wall. The apical impulse is also called the point of maximal impulse (PMI) and is the site where the heartbeat is most strongly felt. The apical pulse is normally the same as the radial pulse but may be different in some situations, such as a tachydysrhythmia. A difference between the radial and apical pulse is called a pulse deficit.
  3. The heart is cone-shaped and the adult heart is approximately 5 inches (12 cm) long, 3.5 inches (9 cm) wide, and 2.5 inches (6 cm) thick. The adult heart typically weighs between 250 and 350 g (approximately 11 oz) and is about the size of a man’s fist (Figure 1-3). Heart size and weight are influenced by age, body weight and build, frequency of physical exercise, and heart disease.
  4. The heart is divided into four cavities or chambers but functions as a two-sided pump. The two upper chambers are the right and left atria, and the two lower chambers are the right and left ventricles.
  5. Terminology Atrium = singular; atria = plural Example: right atrium, right and left atria The right atrial wall is approximately 2 mm thick; the left atrial wall approximately 3 to 5 mm thick. The atria are thin-walled, low-pressure chambers that receive blood. An internal wall of connective tissue called the interatrial septum separates the right and left atria. Externally, the coronary sulcus (groove) encircles the heart and separates the atria from the ventricles. It contains the coronary blood vessels and epicardial fat. Think of the atria as “holding tanks” or “reservoirs” for blood. The right atrium receives deoxygenated blood from the superior vena cava (which carries blood from the head and upper extremities), the inferior vena cava (which carries blood from the lower body), and the coronary sinus (which receives blood from the intracardiac circulation). The left atrium receives oxygenated blood from the lungs via the right and left pulmonary veins. In utero, an opening exists in the interatrial septum called the foramen ovale which allows blood to pass from the right to left atrium. This opening normally closes shortly after birth. There is normally a continuous flow of blood from the superior and inferior vena cavae into the atria. Approximately 70% of this blood flows directly through the atria and into the ventricles before the atria contract. With atrial contraction, an additional 30% is added to filling of the ventricles. This additional contribution of blood because of atrial contraction is called atrial kick.
  6. The ventricles pump blood to the lungs and systemic circulation. An internal wall of connective tissue called the interventricular septum separates the right and left ventricles. Externally, the interventricular sulcus is anatomically divided into the anterior interventricular sulcus and the posterior interventricular sulcus. These grooves indicate the position of the interventricular septum (separating the right and left ventricles) and are perpendicular to the coronary sulcus. The ventricles are larger and have thicker walls than the atria. The left ventricle is a high-pressure chamber that is approximately three times thicker than the right ventricle. To pump blood out of the left ventricle to the systemic circulation, the left ventricle must contract forcefully and overcome arterial pressure and resistance. Each ventricle holds about 150 mL when full and normally ejects only about half this volume (70 to 80 mL) with each contraction.
  7. Left slide… Position of valves in AP Right &amp; left fibrous trigones Right slide…
  8. Schematic of positions around AV groove to describe locations of pathways for WPW &amp; CBT
  9. (L) Arteries… (L) main, LAD, LCx (L) Veins…anterior, ant-lat (R) Arteries…RCA (R) Veins…SCV anterior cardiac… direct to RA
  10. INFERIOR VIEW (DIAPHRAGM ASPECT) (L) Arteries… LCx (L) Veins…CS, posterior, marshall, GCV (R) Arteries…RCA, PDA (R) Veins…SCV, MCV Also note SA node, in this view… posterolateral, others describe more lateral, some say anterolateral
  11. SAN artery, AVN artery Usually branches off RCA…more later