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Drugs used for respiratory system
- 6. Drugs for bronchial asthma
1. Bronchodilators
A. Selective β2 agonists Salbutamol, Terbutaline,
Formoterol, Bambuterol &
Salmeterol
B. Nonselective sympathomimetics Epinephrine,
Ephedrine
C. Methylxanthines Theophylline, Aminophylline
D. Anticholinergics Ipratropium br., Tiotropium br.
- 7. 2. Corticosteroids
A. Oral Prednisone, Prednisolone, Methylprednisolone
B. Parenteral Methylprednisolone, Hydrocortisone
C. Inhalational Beclomethasone, Budesonide, Fluticasone
3. Leukotriene (LT) modulators
A. Cysteinyl LT receptor antag. Montelukast, Zafirlukast
B. 5-Lipoxygenase inhibitor Zileuton
4. Mast cell stabilizers Sodium cromoglycate, Ketotifen
5. Monoclonal Anti-IgE antibody Omalizumab
6. Miscellaneous Nitric oxide donors
- 18. T/t of Status asthmaticus
1. Hydrocortisone hemisuccinate 100 mg i.v. stat
followed by 100-200 mg 4-8 hourly infusion
2. Nebulized Salbutamol (2.5-5 mg) + Ipratropium
bromide (0.5 mg) intermittent inhalations
3. High flow humidified oxygen inhalation
4. Salbutamol/Terbutaline 0.4 mg i.m/s.c.
5. Intubation & mechanical ventilation
6. Chest infection t/t with intensive a.b. therapy
7. Correction of dehydration & acidosis with saline +
Sodium bicarbonate/lactate infusion
- 19. Drugs for cough
1.Antitussives
a) Centrally acting Codeine, Pholcodeine, Noscapine,
Dextromethorphan, Pipazethate
b) Central & peripherally acting Benzonatate
c) Peripherally acting Prenoxdiazine
d) Miscellaneous
- 20. i) Antihistaminics Chlorpheniramine, Diphenhydramine
ii) Pharyngeal demulcents Lozenges, Cough drop
iii) Local anaesthetics Xylocaine, Bupivacaine
2.Expectorants
a) Mucokinetic e. Na/K citrate, KI, Guaiphenesin, NH4Cl
b) Mucolytic e. Bromhexine, Ambroxol, Acetylcysteine
3. Adjuvant antitussives Salbutamol, Terbutaline