Pathology of Pneumonia

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Pathology of Pneumonia:
Broncho- pneumonia,
Lobar Pneumonia,
Lung Abscess,
Lung Fungal Absces,
Normal Lung

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Pathology of Pneumonia

  1. 1. The best way to make your dreams come true is to wake up... — Paul Valery
  2. 2. Pathology of Pneumonia Dr. Venkatesh M. Shashidhar Senior Lecturer in Pathology Fiji School of Medicine
  3. 3. Introduction: <ul><li>Daily 10,000 liters of air - filtered..! </li></ul><ul><li>Pneumonia : Inflammation of lung. </li></ul><ul><li>Respiratory tract infections – commonest in medical practice. </li></ul><ul><li>Enormous morbidity & mortality. </li></ul>
  4. 4. Etiology: <ul><li>Decreased resistance - General/immune </li></ul><ul><li>Virulent infection - Lobar pneumonia </li></ul><ul><li>Clearing mechanism </li></ul><ul><ul><li>Cough Reflex </li></ul></ul><ul><ul><li>Mucosal Injury </li></ul></ul><ul><ul><li>Low Alveolar defense </li></ul></ul><ul><ul><li>Pulmonary edema </li></ul></ul><ul><ul><li>Obstructions </li></ul></ul>
  5. 5. Types: <ul><li>Viral </li></ul><ul><li>Bacterial </li></ul><ul><li>Mycoplasmal </li></ul><ul><li>Fungal </li></ul>
  6. 6. Patterns of Pulmonary infections: <ul><li>Airway - Bronchitis, Bronchiectasis </li></ul><ul><li>Parenchyma </li></ul><ul><ul><li>Pneumonia </li></ul></ul><ul><ul><ul><li>Bronchopneumonia </li></ul></ul></ul><ul><ul><ul><li>Lobar pneumonia </li></ul></ul></ul><ul><ul><li>Lung abscess </li></ul></ul><ul><ul><li>Tuberculosis </li></ul></ul>
  7. 7. Bronchopneumonia <ul><li>Staph, Strep, Pneumo & H. influenza </li></ul><ul><li>Patchy consolidation – not limited to lobes. </li></ul><ul><li>Suppurative inflammation </li></ul><ul><li>Usually bilateral </li></ul><ul><li>Lower lobes common </li></ul><ul><li>Complications: </li></ul><ul><ul><li>Abscess </li></ul></ul><ul><ul><li>Empyema </li></ul></ul><ul><ul><li>Dissemination </li></ul></ul>
  8. 8. Broncho-pneumonia
  9. 9. Broncho-pneumonia
  10. 10. Broncho-pneumonia
  11. 11. Bronchopneumonia - Abscess formation
  12. 12. Bronchopneumonia:
  13. 13. Bronchopneumonia:
  14. 14. Bronchopneumonia - Abscess formation
  15. 15. Lung RSV Pneumonia:
  16. 16. Bronchopneumonia - CT
  17. 17. Bronchopneumonia - CT
  18. 18. Lobar Pneumonia: <ul><li>Fibrinosuppurative consolidation – whole lobe </li></ul><ul><li>Rare due to antibiotic treatment. </li></ul><ul><li>~95% - Strep pneumoniae types 1,3,7& 2. </li></ul><ul><li>Four stages: </li></ul><ul><ul><li>Congestion. </li></ul></ul><ul><ul><li>Red Hepatization. </li></ul></ul><ul><ul><li>Gray Hepatizaiton. </li></ul></ul><ul><ul><li>Resolution. </li></ul></ul>
  19. 19. Lobar Pneumonia:
  20. 20. Lobar Pneumonia – Gray hep…
  21. 21. Lung Abscess: <ul><li>Focal suppuration with necrosis of lung tissue </li></ul><ul><li>Strep, Staph & Gram negative & anaerobes </li></ul><ul><li>Mechanism: </li></ul><ul><ul><li>Aspiration </li></ul></ul><ul><ul><li>Post pneumonic </li></ul></ul><ul><ul><li>Septic embolism </li></ul></ul><ul><ul><li>Neoplasms </li></ul></ul><ul><li>Productive Cough, fever. </li></ul><ul><li>Clubbing </li></ul><ul><li>Complications: Systemic spread, septicemia. </li></ul>
  22. 22. Lung Abscess:
  23. 23. Lung Abscess:
  24. 24. Lung Abscess - Chronic:
  25. 25. Lung Fungal Abscess: Candida
  26. 26. Normal Lung
  27. 27. Normal Lung
  28. 28. The only place where success comes before work is in a dictionary…! Vidal Sassoon

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