Adolescent Suicide to School Psychologists
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2022 Undergraduate Research Symposium: Avery Bacheller My research abstract explains the importance of adolescent suicide by breaking down statistics, defining the discourse community, citing and explaining sources that help build a good argument for my thesis. All of these combined help me to spread awareness and information regarding adolescent suicide.
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Directions:
Each student is required to write an entry per reading assigned in the syllabus (i.e. an entry per chapter and/or
article that is assigned.
Definition:
Annotated bibliographies are a list of references followed by an annotation. Annotations provide a space to
reflect on the quality, validity and soundness of the argument or premise of the reference. Annotations also
include a critical analysis of how the reference relates to other similar research.
Annotated bibliographies are not summaries!
Writing Requirements:
-Each annotated entry should be between 150-200 words in length.
-APA or MLA Formatting Style
Annotated Bibliographic Entries:
Address the following:
What are the main arguments/points of the article/chapter?
What methodology was used?
How does this relate to other related readings?
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Cite strong or interesting quotes/evidence.
What lingering questions remain?
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Gándara, P. (1995). Over the ivy walls: The educational mobility of low-income Chicanos. New York:
State University of New York Press.
Gándara (1995) conducted 50 one-on-one interviews with Chicanas/os) who successfully navigated
the higher education system for purposes of upward mobility. In contrast to most research on Chicana/o
students (which student failure), the author conducted a study of successful Chicana/os who all obtained JD,
Ph.D. or MD degrees and attended competitive U.S. universities. Two-thirds of her sample was the first
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tactics Chicana/o parents utilized to instill achievement motivation were the same strategies the literature
reports that middle class parents employ. For example, she noted, “They, (especially the mothers) were very
supportive of their children’s educational goals, set high performance standards, modeled and encouraged
literacy, and helped with schoolwork” (p.111). Further, she argued that her sample’s parents were very
supportive, tended to encourage both sons and daughters equally, and mothers were especially strong
influences, as well as contributors to the family income (Gándara,1995). By moving away from a deficit
model framework, the author makes a great contribution to the literature on first and second-generation
college-attending Chicanas/os.
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Laosa (1984) notes that in every epoch over the past four centuries, specific
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Suicide is a serious issue on college campuses, with over 1,000 students committing suicide each year. It is the second leading cause of death among college students. Several best practices can help prevent suicide and contagion, including implementing a death response team after a suicide occurs and addressing the student body to dispel myths. Providing accessible mental health resources is also important, as poor mental health negatively impacts academics. Innovative outreach programs can help universities connect with at-risk students.
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Annotated Bibliography Guidelines Directions Each stud.docx
Annotated Bibliography Guidelines
Directions:
Each student is required to write an entry per reading assigned in the syllabus (i.e. an entry per chapter and/or
article that is assigned.
Definition:
Annotated bibliographies are a list of references followed by an annotation. Annotations provide a space to
reflect on the quality, validity and soundness of the argument or premise of the reference. Annotations also
include a critical analysis of how the reference relates to other similar research.
Annotated bibliographies are not summaries!
Writing Requirements:
-Each annotated entry should be between 150-200 words in length.
-APA or MLA Formatting Style
Annotated Bibliographic Entries:
Address the following:
What are the main arguments/points of the article/chapter?
What methodology was used?
How does this relate to other related readings?
Does the author provide sufficient evidence?
Cite strong or interesting quotes/evidence.
What lingering questions remain?
Sample Annotated Bibliographic Reference on First-generation Chicana/o College Students:
Gándara, P. (1995). Over the ivy walls: The educational mobility of low-income Chicanos. New York:
State University of New York Press.
Gándara (1995) conducted 50 one-on-one interviews with Chicanas/os) who successfully navigated
the higher education system for purposes of upward mobility. In contrast to most research on Chicana/o
students (which student failure), the author conducted a study of successful Chicana/os who all obtained JD,
Ph.D. or MD degrees and attended competitive U.S. universities. Two-thirds of her sample was the first
generation to be born in the U.S. Gándara found through her retrospective interviews that many of the
tactics Chicana/o parents utilized to instill achievement motivation were the same strategies the literature
reports that middle class parents employ. For example, she noted, “They, (especially the mothers) were very
supportive of their children’s educational goals, set high performance standards, modeled and encouraged
literacy, and helped with schoolwork” (p.111). Further, she argued that her sample’s parents were very
supportive, tended to encourage both sons and daughters equally, and mothers were especially strong
influences, as well as contributors to the family income (Gándara,1995). By moving away from a deficit
model framework, the author makes a great contribution to the literature on first and second-generation
college-attending Chicanas/os.
4
At-Risk Students or At-Risk Schools?
My goal in this chapter is to provide a comprehensive coverage of the social
construction of the “at-risk” term,1 a deficit thinking notion. I do so by
organizing this discussion around four sections.
Historical Origins of the At-Risk Notion
Laosa (1984) notes that in every epoch over the past four centuries, specific
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All Res Life staff members are going to encounter students suffering from anxiety disorders at some point.
This session helped train Resident Assistants on different types of disorders, how to recognize symptoms of anxiety, and how to be a resource for students who may have an anxiety disorder.
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Psychology is the scientific study of behavior and mental processes. There are several primary perspectives in modern psychology including psychoanalytic/psychodynamic, behaviorism, humanistic, cognitive, neuroscience/biopsychology, evolutionary psychology, and sociocultural approaches. Psychologists work in a variety of career specialties such as research, teaching, mental health services, and applied settings. Popular specialties include clinical, counseling, developmental, cognitive, social, industrial/organizational, gender/cultural, and experimental psychology.
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The document discusses various models of therapeutic education and mental illness. It describes the medical, psychodynamic, behavioral, social, and family therapy models of understanding psychiatric disorders. It also discusses models that explain illness dynamics, such as the bio-psycho-social model and preventive model. Additionally, it outlines the person-centered care model of therapeutic education, which addresses the person holistically rather than just their symptoms. Finally, it poses questions about how to effectively implement psychoeducation programs.
Emerging Schools of Thought in Psychology.pptx
This PPT is aims to provide knowledge and understanding about Emerging schools of thought in psychology and its Example.
CHHS Presentation 2
The document discusses the issue of depression among college students. It finds that stress is the number one cause of depression in college students. Suicide is the second leading cause of death on college campuses. The campus being discussed, CSUMB, currently has limited resources to help students with depression aside from the campus health center. Potential solutions proposed include establishing peer counseling centers, promoting stress management techniques, and providing more information through meetings and screening tests. The synthesis argues that educating students is key to preventing and treating depression, and that stress management can reduce the likelihood of developing depression.
Learning Styles: Concepts and Evidence. Harold Pashler, Mark McDaniel, Doug R...
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Educational psychology is the branch of psychology that studies how people learn in educational settings, both in and out of school. It aims to apply psychological insights and principles to understand and improve educational practice. Some key areas it covers are understanding learners, selecting learning experiences, teaching techniques to facilitate learning, and evaluating learning outcomes. It provides a scientific basis and practical guidance to help create effective learning environments and experiences for students.
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Amidst the ever-expanding cosmos of scientific literature, the quest for tools that can deftly extract and analyze data from publications has grown increasingly vital. Enter LoA (Librarian of Alexandria), a Linux-Python tool that harnesses the power of artificial intelligence to scour chemistry-related papers, meticulously extracting invaluable textual measurements and data into structured Excel files.
This approach engenders the formation of an expansive, high-quality dataset, poised to train predictive models in assessing the properties of chemicals, proteins, and other compounds, with a predominant emphasis on the field of chemistry. LoA's sophisticated AI algorithms artfully decipher and extract essential information from intricate scientific documents. Although the tool currently focuses on extracting text, plans for future iterations include deciphering images and delving into deeper analysis. LoA's potential transcends the realm of chemistry, with prospective applications in diverse scientific disciplines such as materials science, biology, and pharmacology, by tailoring the extraction process to the domain at hand.
Like the ancient Library of Alexandria, LoA aspires to become a beacon of knowledge, a comprehensive instrument for navigating the vast ocean of human intellect. As it is presented at an undergraduate research symposium, this innovative tool embodies the potential for revolutionizing scientific research, opening doors to interdisciplinary applications, and illuminating the path to discoveries yet unimagined. Embracing the beauty of imperfection, LoA continues to evolve, a testament to the resilience and adaptability that characterizes the boundless realm of scientific inquiry.Economic Relief Provided by the OLLIF Surgical Technique
Economic Relief Provided by the OLLIF Surgical TechniqueWayne State University College of Liberal Arts and Sciences
2023 Undergraduate Research Symposium: Carly Ghanem
The standard treatment for lower back pain has been interbody fusion: Transforaminal Lumbar Interbody Fusion (TLIF). The invasive nature leads to muscle detachment and damaged nerves. To address these issues, minimally invasive (MI) TLIF techniques have been developed.
While MI TLIFs show decreased blood loss and complication rates relative to open TLIF, surgery times and long-term outcomes are reported to be similar. Oblique lateral lumbar interbody fusion (OLLIF) is a MI lumbar spinal fusion through a single 10-15 mm incision, with a faster surgery time and easier approach. Anesthesia, surgery times, and blood loss were recorded for all patients that entered into the EMR. Because no suction is used in OLLIF procedures, blood loss was measured by weighing sponges and subtracting dry weight.
To monetize the cost per minute for a hospital, a published reference was utilized and adjusted with the consumer price index. These values were reported in aggregate and stratified, based on spinal level(s) of surgery. Mann-Whitney U-tests were utilized to test the null hypothesis that the OLLIF and TLIF groups have the same or identical mean distributions for age, BMI, blood loss, and uncensored time duration variables. Data analyses were performed using IBM SPSS. A shorter length of stay than TLIF by 58.5% across all surgeries studied was found.
The trend of shorter lengths of stay remained consistent when surgeries were stratified based on the spinal level(s) involved. OLLIF also had a lower surgical admission cost than TLIF, with a difference of $6,701 versus $11,583. These findings suggest that OLLIF may be a more cost-effective and efficient alternative to TLIF for treating lower back pain, particularly for hospitals with limited resources.A Transposon Insertion Site Identifies Two Potential Genes That Regulate a De...
A Transposon Insertion Site Identifies Two Potential Genes That Regulate a De...Wayne State University College of Liberal Arts and Sciences
2023 Undergraduate Research Symposium: Kira Jonatzke
Under favorable environments, the worm C. elegans undergoes four different larval stages before becoming a fertile adult. However, when environments are harsh, such as under high temperatures or high population density and low food availability, C. elegans enters a different developmental program, known as dauer.
Dauers are developmentally arrested, highly resistant to stress and live long. Thus, when environments improve, dauers exit to the last larval stage and become fertile adults. Recently, we serendipitously discovered that the Mos1 transposon insertion site ttTi5605 produced more dauers at high temperatures, when compared to wild-type animals. This Mos1 insertion site is situated between two genes, the predicted glucose transporter FGT-2 and the F14E5.8 gene of unknown function.
Thus, the Mos1 transposon insertion might alter the expression of FGT-2 and/or F14E5.8, which potentially suggests a role for at least one of these proteins in regulating the switch to the dauer program.Mild Intermittent Hypoxia: A Prophylactic for Autonomic Dysfunction in Indivi...
Mild Intermittent Hypoxia: A Prophylactic for Autonomic Dysfunction in Indivi...Wayne State University College of Liberal Arts and Sciences
2023 Undergraduate Research Symposium: Lexi Soltesz
A central health issue for those with a chronic spinal cord injury (SCI) above the sixth thoracic vertebrae is autonomic dysfunction. Autonomic dysfunction results in significant increases and decreases in blood pressure and negatively affects health-related quality of life.
This uncontrolled blood pressure also negatively impacts cognitive function and adherence to rehabilitation programs. Additionally, the lesion itself impairs motor function thereby resulting in decreased physical activity and impaired mitochondrial function. Moreover, autonomic dysfunction can lead to an increased risk of stroke, and therefore increased mortality. Mild intermittent hypoxia (MIH), an experimental protocol in which participants experience lower oxygen, in a controlled and repetitive sequence, has been shown to improve blood pressure control in humans.
Our study aims to investigate the impact of MIH on autonomic dysfunction during in-lab provocation and during in-home testing. Likewise, we will also investigate the impact of MIH on mitochondrial and microvascular function and motor function. Our preliminary data shows that MIH may improve autonomic dysfunction which may be explained by improvements in baroreceptor and/or mitochondrial and endothelial function. As evidenced by our preliminary data, MIH is a promising potential protocol for improving health-related quality of life in those with SCI.Utilization of In vivo Longitudinal PET Imaging to Assess Class IIa HDAC Acti...
Utilization of In vivo Longitudinal PET Imaging to Assess Class IIa HDAC Acti...Wayne State University College of Liberal Arts and Sciences
2023 Undergraduate Research Symposium: Mahmoud Teran
The development of memories, including those throughout extinction learning, require neuroplasticity for encoding and retrieval to occur. As environmental factors can affect gene expression, epigenetic changes can play a critical role in the development of memory formation and updating and ultimately manifesting in behavioral changes reflective of the learning.
The purpose of the current project is to show the utility of Positron Emission Tomography (PET), a functional, molecular imaging technique that employs radioactive substances to measure specific markers in the brain. As part of our efforts to understand the neurobiological mechanisms of fear learning and the role of epigenetic changes using PET, images of the brains were collected before and after extinction learning of acquired long-term fear (LTF) memories induced by shock tone pairings made every 30 seconds over 38 min.
PET images were collected by injecting the radiotracer [18F]TFAHA, a substrate for class IIa histone deacetylases (HDACs). The resulting accumulation of the breakdown product of [18F]TFAHA could be considered as a proxy for class IIa HDAC expression changes before and after LTF memory. HDAC activity is directly related to gene expression changes through deacetylation of histone lysine residues. This results in a closed chromatin conformation and prevents the binding of RNA polymerase II and ultimate gene transcription and protein synthesis.
This can then be manifested and seen as behavioral change. Our preliminary analysis of PET images results indicate a significant interaction effect between pre-to-post class IIa HDAC expression-activity, sex, and shock condition. Additional PET image analysis is anticipated to show the extent of HDAC activity in both the sexes following LTF.Developmental Defects in Adolescents as a Result of the Pandemic.pptx
Developmental Defects in Adolescents as a Result of the Pandemic.pptxWayne State University College of Liberal Arts and Sciences
2022 Undergraduate Research Symposium: Christina Kort
There are five developmental factors discussed throughout the review that are applicable to adolescents during the pandemic. This involves the incorporation of nutrition and exercise health, in which a lack of physical activity or appropriate eating habits may be hindering growth.
Learning experiences have been altered to a digital platform and have deeply affected students' motivation and cognitive engagement. Forming strong social connections with friends and members of the community is another way to help ensure that developing brains are progressing. In some cases, the home environment may be negatively impacting the ability to complete work or achieve personal space. Taking some time away or setting boundaries around family may be crucial for growth.
The last aspect necessary for adolescents to sustain positive development consists of a daily structure. Staying active in recreational activities is a good way to ensure structure and can greatly benefit the other factors related to forming new bonds and getting physical exercise.Investigating High Rates of Suicidal Ideation in Individuals Who Stutter
Investigating High Rates of Suicidal Ideation in Individuals Who StutterWayne State University College of Liberal Arts and Sciences
2022 Undergraduate Research Symposium: Mary Tooma
Graduate co-author: Emily Graham LeRose
This research was conducted to investigate the underlying etiological cause(s) and/or psychosocial contributions to suicidal ideation as highly self-reported among individuals with a developmental stutter.
A comprehensive literature review was completed to explore two of the hypothesized components thought to increase risk for suicidal ideation in this population; genetic heritability of suicidal ideation and the presence of co-morbid mental health disorders arising as a result of having a stutter (i.e., depression, anxiety, etc.). Additionally, an empirical review was completed for recommendations to improve overall outcomes in therapy for individuals who stutter.
Results from this investigation of the literature found the most empirical support for a connection between high rates of co-morbid mental health disorders and suicidal ideation in individuals who stutter. Additionally, a therapeutic approach titled "Attachment-Based Family Therapy" has been shown to be highly effective in treating individuals, particularly adolescents, who experience suicidal ideation and depression.Iridium (III) Complexes as Sensors for Cytochrome P450 Enzymes
Iridium (III) Complexes as Sensors for Cytochrome P450 EnzymesWayne State University College of Liberal Arts and Sciences
2022 Undergraduate Research Symposium: Justin Ahrens
Graduate co-author: Maddy Denison
The main goal of this project is to use IrIII complexes to monitor cytochrome P450 (CYP) activity. CYP P450 metabolism determines how quickly drugs are excreted from the body and what kind of dose is required for pharmaceuticals to be effective.
Existing probes for CYPs are non-fluorescent, but when CYPs metabolize them, they are “turned on” and fluoresce. Even though these probes are able to monitor metabolism, once they are metabolized and “turned on” they cannot be reversed or turned off. Therefore, this is no current way to monitor dynamic changes in CYP activity continuously over time.
The Kodanko laboratory is addressing this unmet need by developing IrIII complexes that are reversible sensors of CYP enzymes. A chiral resolution strategy with enantioenriched ligands was used to prepare four analogs of IrIII complexes with different stereochemistry. These complexes were evaluated as emissive sensors in human liver hepatocytes to establish which IrIII complex is the lead compound for sensing CYP in living cells. Results from this multi-disciplinary study will be reported.Mental Health and Incarceration
2022 Undergraduate Research Symposium: Bahea Nasser
My research is overall in the issue of the mass incarceration rate of people with serious mental illness. My research goes into detail about the factors and causes of this problem, re-offending, deinstitutionalization, other important information, and how people with serious mental illness in the criminal justice system receive inadequate treatment.
Accounting Evolution
2022 Undergraduate Research Symposium: Tareq Murshed
Accounting has had major developments and throughout the years it has went from pen and paper to paperless.
Misuse of Analgesics and How They Contribute to the Opioid Epidemic
Misuse of Analgesics and How They Contribute to the Opioid EpidemicWayne State University College of Liberal Arts and Sciences
2022 Undergraduate Research Symposium: Hanna Alfasih
This research is about the misuse of analgesics and how they have contributed to the opioid epidemic.How Can CRNAs Better Help/Understand Their Patients?
How Can CRNAs Better Help/Understand Their Patients?Wayne State University College of Liberal Arts and Sciences
This document summarizes a presentation on how CRNAs can better help and understand their patients. It discusses several ways for CRNAs to improve patient care and understanding, such as understanding how the healthcare system works to help patients with affordable treatment options, staying updated on new technologies, learning to communicate collaboratively with anesthesiologists, and understanding patients' financial stresses. The presentation also reviews 6 articles on related topics and identifies some limitations in finding relevant sources. It concludes that sharing this information could help medical staff better understand and care for patients to reduce their emotional and physical stress.The Male and Female Gaze in Film Theory
2022 Undergraduate Research Symposium: Ma'ldah Sheikh
The male gaze is a point of view in literary and digital media. It is from the viewing pleasure and perspective of heterosexual men. This form of content is predominantly characterized by the objectification and sexualization of women and other minority groups. The female gaze is meant to oppose the male gaze in cinema, but there are many controversies pertaining to this within the film discourse community.
Many theorists debate that there is no such thing as the female gaze, while others argue that even with the existence of the female gaze, the male gaze can never truly be reversed.
WSU CAPS Resource: Mental Health Screening Utilization
WSU CAPS Resource: Mental Health Screening UtilizationWayne State University College of Liberal Arts and Sciences
2022 Undergraduate Research Symposium: Vivian Truong
Young adults (18-25) have the highest prevalence (29.4%) of any mental illness and the lowest rate of receiving mental health services (38.9%; NIMH). WSU CAPS provides Wayne State students with an online mental health screening opportunity. The numbers of screenings were of interest for this project.
COVID-19 has been shown to negatively impact students’ social and academic engagement, as a result, screening usage during the pandemic was expected to increase. Additionally, the literature on gender and racial/ethnic disparities in mental health service utilization suggest that screening tools may be used less by men and underrepresented minorities. We also expected gender and racial disparities in use, despite the anonymity provided by online screening.
We examined screening use during the pandemic from 3/15/2020 to 6/15/2021 in comparison with pre-pandemic use from 3/15/2018 to 6/15/2019. It is found that the rate of screening is slightly elevated during the pandemic. Secondly, the rate of screening use among different demographic groups, specifically racial/ethnic groups, and gender groups during the fall of 2020 was explored. Of the 897 screenings that were completed, White completed more than 50% of them. Black students were less likely to be screened (12.2% versus 14.8%, p < .01), as were Hispanic students (3.3% versus 5%, p < .001).
Surprisingly, Asian students were more likely to complete the screening (16% versus 10.2%, p < .001). Students who identified as male were highly underrepresented among those who completed the screenings (17.5% versus 40.7% of students).Are Health Awareness Months Dedicated to Urological Diseases Effective at Inc...
Are Health Awareness Months Dedicated to Urological Diseases Effective at Inc...Wayne State University College of Liberal Arts and Sciences
2022 Undergraduate Research Symposium: Shane Tinsley
Introduction: Disease-specific health awareness (HA) campaigns have rapidly developed as an important avenue to improve patient education and ideally outcomes. Our study objective was to understand the impact of urological HA months on engaging public search interests in the United States.
Methods: We utilized Google Trends to examine public health interest in urologic conditions during monthly awareness campaigns over a 17-year period (2004-2021). Relative Search Volume (RSV) during the annual HA campaign months relative to non-health awareness (NHA) campaign months was calculated. Differences between HA-RSV and NHA-RSV months were compared using t-test.
Results: Although small increases in public interest were noted for certain diseases (prostate cancer in November, testicular cancer in April and erectile dysfunction), there was interestingly a comparative decrease in RSV for other diseases (bladder cancer, prostate cancer in September, testicular cancer in November, kidney cancer, benign prostate hyperplasia and male infertility) in their respective HA months; however, none of these differences were statistically significant (p > 0.05).
Conclusion: Our study did not find a significant difference in public interest of any urological diseases during their respective HA campaign months. This highlights the critical need for further research to investigate potential improvements in campaign methodology during dedicated HA months to better achieve their goals of increased public health engagement.The Importance of Rural Family Physicians
The Importance of Rural Family PhysiciansWayne State University College of Liberal Arts and Sciences
2022 Undergraduate Research Symposium: Taha Kader
Family physicians are crucial to providing appropriate medical care in rural areas. Family physicians tackle various roles such as maternity and emergency care in these areas. However, there aren't nearly enough family physicians in these areas, and something needs to be done.Quality Matters: A Procedure for Valid and Reliable Hippocampal Subfield Segm...
Quality Matters: A Procedure for Valid and Reliable Hippocampal Subfield Segm...Wayne State University College of Liberal Arts and Sciences
2022 Undergraduate Research Symposium: Samaah Saifullah
Graduate co-author: Kelsey L. Canada
Automated hippocampal subfield segmentation methods have led to exponential growth in the literature. Although automated segmentation is perfectly reliable, deviations from anatomical definitions are common and weaken their validity.
To address the lack of guidance for quality control (QC) of automated segmentation methods, we developed a taxonomy of errors and two-step protocol for 1) identification and 2) manual correction. Raters examined segmentations from a customized atlas to identify errors in six categories with severity ratings; only major severity errors are manually corrected in order to minimize introducing human error.
The QC procedure was developed and cross-validated with an independent sample on two MRI scanners. Raters had excellent agreement in QC decisions between- and within-raters on all regions, manual corrections introduced less than 3% error and were unrelated to participant demographic.
The feasible and reliable QC procedure allows confident interpretation of hippocampal subfield segmentations, and potential applications to other brain regions.Identification of Novel Inhibitors Targeting KRAS-SOS1 Interactions by Struct...
Identification of Novel Inhibitors Targeting KRAS-SOS1 Interactions by Struct...Wayne State University College of Liberal Arts and Sciences
2022 Undergraduate Research Symposium: Neel Patel and Mariana Sierra
The Kristen Rat Sarcoma (KRAS) protein, encoded by the KRAS gene, is a signal transducer that plays a crucial role in regulating cell proliferation. KRAS mutations have been known to cause lung, colorectal, and pancreatic cancers. Previously, KRAS was considered an “undruggable” target. However, with better understanding of the protein’s biology paired with advanced new technologies, the FDA approved the first KRAS inhibitor (sotorasib) for lung cancer patients with the KRASG12C mutation in 2021, expressing the recent interest of targeted drugs for KRAS.
In clinical trials, sotorasib proved ineffective for pancreatic and colorectal cancers with the G12C mutation. Irrespective of mutant identity, oncogenic KRAS requires activation by the guanine nucleotide exchange factor (GEF) Son of Sevenless 1 (SOS1), highlighting an exploitable vulnerability with broad therapeutic applicability. The goal of this study is to develop novel pan-KRAS inhibitors by targeting the KRAS-SOS1 interactions through computational modeling. To start, we applied Gaussian accelerated molecular dynamics (GaMD) simulation, an advanced conformational sampling method, to collect the nature of the KRAS protein motion in solution. Then, the clustering analysis method was used to assemble KRAS conformational structures into ten groups for later virtual screening and docking simulations.
We aim to address 20 to 30 compounds to later be experimentally assessed for their (1) ability to disrupt the KRAS-SOS1 interactions and (2) cytotoxicity in KRAS mutation-bearing cell lines. The work will provide insights in the drug efficacy of KRAS inhibitors and give rise to a novel set of KRAS candidates to be used in clinical oncogenic treatments.More from Wayne State University College of Liberal Arts and Sciences (20)
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- 1. ADOLESCENT SUICIDE IS THE MOST IMPORTANT TOPIC FOR SCHOOL PSYCHOLOGISTS Avery Bacheller
- 2. SUMMARY OF PRESENTATION • Synthesis Map -Connects the research • Common themes in research -Helps to narrow down an answer to my research question • Research Sources and question -Credible sources that fit the research question
- 3. RESEARCH QUESTION • What is the most important topic for School Psychologists?
- 5. COMMON THEMES IN SYNTHESIS MAP • -Adolescent Suicide • -Suicide prevention programs • -Stressors on young children • -Suicide Stigma • -Obligations of School Psychologists
- 6. SOURCES • Source #1 Miller, D. N. (2013). Lessons in suicide prevention from the golden gate bridge: Means restriction, public health, and the school psychologist. Contemporary School Psychology, 17(1), 71-79. Retrieved from https://proxy.lib.wayne.edu/login?url=https://www.proquest.com/schola rly-journals/lessons-suicide-prevention-golden-gate- bridge/docview/2001011767/se-2?accountid=14925 • Important themes: Youth Suicide, Suicide prevention, Mental Health crisis. • It has been suggested that suicide may be the most stigmatized form of human behavior (Joiner, 2005). Stigma, which "combines fear with disgust, contempt, and lack of compassion, all of which flow from ignorance" (Joiner, 2010, p. 272)
- 7. SOURCES • Source #2: Erps, Kristen Herner, "School Psychologists and Suicide Risk Assessment: Role Perception and Competency" (2018). Masters Theses & Specialist Projects. Paper 3062. https://digitalcommons.wku.edu/theses/3062 • Important Themes: Youth suicide, Depression, Suicide Prevention • Statistics on suicide
- 8. SOURCES • Source #3: Baker, D. A. (2020). Etd.ohiolink.edu. SCHOOL PSYCHOLOGISTS’ SUICIDE PREVENTION AND INTERVENTION PREPAREDNESS. Retrieved February 21, 2022, from https://etd.ohiolink.edu/apexprod/rws_etd/send_file/send?accession=mi ami1155143421&disposition=inline • Important topics: Suicide postvention, glamorization of suicide, career obligation
- 9. SOURCES • Source #4: Eckert, T. L., Miller, D. N., DuPaul, G. J., & Riley-Tillman, T. C. (2003). Adolescent suicide prevention: school psychologists' acceptability of school-based programs. (General Articles). School Psychology Review, 32(1), 57+. https://link.gale.com/apps/doc/A101614310/AONE?u=googlescholar&si d=bookmark-AONE&xid=46cece26 • Important topics: Suicide prevention programs, acting-out behavior, adolescent suicide.
- 10. CONCLUSION • Adolescent suicide is the most important topic for school psychologists