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SCIENCE ARTICLE 
ENDOSULFAN 
Endosulfan is a DDT-era insecticide that persists in the environment and in our 
bodies. EPA data show that all of us are routinely exposed to small amounts of 
endosulfan in the food we eat, with young children receiving the largest doses. Studies 
of popluations exposed to endosulfan have been published suggesting that endosulfan 
can increase the risk of autism, delay puberty in boys, and cause birth defects of the 
male reproductive system. 
Human Health Harms 
Endosulfan attacks the central nervous system, causing overstimulation and a range of 
health harms. Acute exposure to endosulfan causes headaches, nausea and vomiting, 
seizures, and in extreme cases, unconsciousness and death. The EPA classifies 
endosulfan in its most extreme toxicity category (highly acutely toxic) because 
relatively small doses prove lethal in labratory studies. 
Endosulfan related deaths and debilitation are common is the developing world, where 
endosulfan is cheap but personal protective equipment is expensive or even 
impossible to obtain. Examples include thirty-seven farmers dying in Benin, two boys 
dead in South Africa, flower workers poisoned in Colombia, and villagers in 
Philippines and India poisoned by the toxic pesticide. 
Endosulfan and cancer 
Endosulfan is not listed as known, probable, or possible carcinogen by the EPA, 
IARC, or other agencies. No epidemiological studies link exposure to endosulfan 
specifically to cancer in humans, but in vitro assays have shown that endosulfan can 
promote proliferation of human breast cancer cells.[50] Evidence of carcinogenicity in 
animals is mixed.[16]
Endosulfan - sreekkutty sb

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Endosulfan - sreekkutty sb

  • 1. SCIENCE ARTICLE ENDOSULFAN Endosulfan is a DDT-era insecticide that persists in the environment and in our bodies. EPA data show that all of us are routinely exposed to small amounts of endosulfan in the food we eat, with young children receiving the largest doses. Studies of popluations exposed to endosulfan have been published suggesting that endosulfan can increase the risk of autism, delay puberty in boys, and cause birth defects of the male reproductive system. Human Health Harms Endosulfan attacks the central nervous system, causing overstimulation and a range of health harms. Acute exposure to endosulfan causes headaches, nausea and vomiting, seizures, and in extreme cases, unconsciousness and death. The EPA classifies endosulfan in its most extreme toxicity category (highly acutely toxic) because relatively small doses prove lethal in labratory studies. Endosulfan related deaths and debilitation are common is the developing world, where endosulfan is cheap but personal protective equipment is expensive or even impossible to obtain. Examples include thirty-seven farmers dying in Benin, two boys dead in South Africa, flower workers poisoned in Colombia, and villagers in Philippines and India poisoned by the toxic pesticide. Endosulfan and cancer Endosulfan is not listed as known, probable, or possible carcinogen by the EPA, IARC, or other agencies. No epidemiological studies link exposure to endosulfan specifically to cancer in humans, but in vitro assays have shown that endosulfan can promote proliferation of human breast cancer cells.[50] Evidence of carcinogenicity in animals is mixed.[16]