introductiion, classification of antiulcer

1. Ulcer is erosion in the
lining of stomch or the
first part of the small
intestine called
duodenum

2.  Reduction of gastric acid secretion
(a) H2 antihistamine
Example :- cimetidine,rantidine etc
(b)PPIs (proton pump inhibitor):-
Example:-omeprazole,rabeprazole,pentoprazole
etc
(c)Anticholinergic:-
Example:- pirenzepine,propanthaline etc
(d)Prostaglandin analogue:-
Example:- misoprostol,enprostil etc

3.  Systemic :-
Example:-sodium bicarbonate,sodium citrate
 Non systemic (local ):-
Example :-Mg hydroxide,Mg trisilicate ,Al
hydroxide,gel,calcium carbonate
Ulcer protective:-
Example:-CBS(colloidal bismuth
subcitrate),sucralfate

4. Example :-cabenoxolone sodium
Anti.H.pyloric drugs:-
Example :-amoxicillin metronidazole
tinidazole