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TRANSRADIAL 
ENDOVASCULAR Iliac and 
Femoral INTERVENTIONS 
Chicago AIM R a d i a l 2014 
John Coppola 
NYU Langone Medical Center
Overview 
 1. Why TRA for Endovascular Iliac Interventions? 
 2. Anthropometric Measurements 
 Limitations and needs
Bleeding 
2004-2011 3,386,688 PCIs 
1.7% bleeding episodes 
Increased risk for mortality of 12.1% 
Chhatriwella JAMA 3/13/2013
Radial Artery-Ideal Access 
Site 
 Easily accessible even in subjects with severe PVD 
 Cannulation benefit for most arterial beds (natural blood flow) 
 Major advantage in terms of bleeding complications1,2 
 Improved quality of life3 
 Time-sparing hemostasis 
 Same-day discharge 
Kiemeneij F, et al. ACCESS Trial. JACC, 1997 
RIVAL Trial. Lancet 2011 
Cooper CJ, et al. Am Heart J, 1999
ACCUITY - Access 
Radial (798) Femoral (11988)
advantages 
 Absent or markedly decreased pulse 
 Difficult to crossover in calcified vessels 
 “ upside down “V” 
 Ostial disease on contralateral side 
 Low external iliac disease 
 Avoid closure device or compression distal to 
fresh stent
Most patients making radial 
first 
My practice
How 
 Use left radial saves crossing arch 
 Start with short introducer give cocktail 
 LIMA if wire does not go right into DA always 
follow passage of wire down to avoid damage 
to branch vessels of aorta 
 With exchange wire in DA exchange for long 
sheath Cook 110 or Terumo 90 cm 
 Self expanding 5Fr or 6Fr balloon expandable 
many need 7Fr of “free wire”
How 
 Use long wire for exchange 
 If 0.014” system viper wire from CSI 360cm 
can usually use 0.14 exchange wirers 
 Super core 0.035 300 cm wire
Anthropometric measurements 
Wrist - Subclavian = 50- 
65cm 
L Wrist - Renal A = 90cm 
L Wrist - Common Iliac = 105-115cm 
R Wrist - R Carotid = 55-65cm 
R Wrist - L Carotid (bovine arch) = 
55-65cm 
L Wrist - CFA = 125- 
135 cm 
L Wrist - Popliteal A= 155- 
170 cm 
L Wrist - Foot= 200-230 
cm
Left Radial Artery 
vs R-Radial 
 1. Gain about 5-8 cm 
 2. Avoid the innominate a. tortuosity 
 3. Avoid catheter manipulation in the aortic arch
TRANSRADIAL 
for Endovascular Interventions 
BASIC EQUIPMENT 
Introducer Sheaths: 5 and 6 Fr 90 cm (Terumo); 110 cm (Cook) 
Wires: 0.014 / 330 Viper (CSI); 0.035 / 300 Supracor (Abbott); 0.035 hydrophilic coating (Terumo; Cordis) 
Balloons: 
up to 5.0 mm diameter - 150 cm shaft (most balloons) 
5.5mm and up - longest shaft 135 (Abbott, EV3) 
Scoring Balloons: 
Angiosculpt - 5 Fr - up to 6.0 - 137-139cm shaft 
Cutting Ballons - 6 Fr - 137 cm 
Stents: 
the only 5 Fr platform - Zilver stent (Cook) -125cm 
6 Fr platform - longest shaft 135 (Abbott)
TRANSRADIAL 
for Endovascular 
Interventions ADVANCED EQUIPMENT 
 CTO Devices: 
 CROSSER (Bard) - 146 cm shaft - 6Fr (14S) 
 Wildcat (Avinger) 6Fr - 110 cm; 5Fr - 140 cm 
 Frontrunner (Cordis) - 140 cm 
 Reentry Devices: 
 Outback (Cordis) - 6 Fr - 120 cm 
 Pioneer (Medtronic) - 6 Fr - 120cm 
 Atherectomy: 
 DB 360 (CSI) - 146 cm shaft - all crowns fit in 6 Fr (except 2.25mm) 
 IVUS: 
 Volcano - 150 cm 
 Atlantis (Boston Scientific) - 135 cm
Iliac Artery Stenting 
 L radial is preferred (gain aprox 10 
cm) 
 5-6 Fr / 110 cm introducers 
 Any unilateral angioplasty and 
stenting can be performed either 
with 5Fr compatible self-expandable 
stents (Cook 
Medical), or balloon expandable 
stents
Iliac Artery Stenting 
6 Fr 110cm sheath 
Post Stenting 
330 cm 0.014” Viper wire
Transradial Iliac 
Stenting 
 80 iliac lesions treated via TRA (28%CTO) or TFA (9% CTO) 
Conclusions: 
1. Similar contrast use (238 vs 213 ml) 
2. Similar fluoroscopy time (30 vs 27 min) 
1. Shorter time to discharge (14.4 vs 20.9 hrs) 
2. Lower access-site complications (0 vs 7.2%) 
Staniloae et al. Cath Cardiovasc interv 2009
CFA Interventions 
 No stent zone 
 Frequently - atherectomy + PTA 
 Most atherectomy devices require 7 Fr 
introducer sheaths 
 DB360 - CSI - the only atherectomy 
device 6 Fr compatible
CFA Interventions 
Left radial access 
Right CFA occlusion Left CFA occlusion
CFA Interventions 
Shuttle sheath, 6Fr/ 110cm/ 0.087” via left radial access 
CROSSER 14S 
Calcified CFA, SFA, PFA
CFA Interventions 
DB 360 - 2.0 SC 30 
PTA 6.0 mm balloon
CFA Interventions 
Post PTA 6.0 at 4 atm 
Residual Calcified 
Eccentric Stenosis 
Residual calcified plaque at the bifurcation
CFA Interventions 
Wire in PFA DB 360 SC 
Final result
New Frontiers 
SFA / Popliteal 
 Currently - severe limitations do to lack of 
adequate equipment 
 Proximal SFA: 
 PTA 
 Atherectomy with DB 360 - shaft length 146 cm 
 Occasionally - stenting (135 cm)
Proximal SFA 
5 Fr 110 cm sheath 
Edge restenosis post 
Viabahn stent 
Angioscupt 5.0/40
Limitations of TRA for 
Endovascular Interventions 
 Lack of adequate transradial training 
 Limited equipment 
 Paucity of clinical studies
Equipment Shortage 
There is a need for: 
1. Larger variety of introducer sheaths (90 / 100 / 110 / 125 cm) 
2. Ballon catheters with shaft lenghts up to 170-180 cm 
3. Longer Guidewires (360-380cm) 
4. Stents with shaft lenghts up to 170-180cm 
5. CTO / Reentry devices longer and lower profile
SFA 
 Same procedure as iliac 
 Devices limited to balloon 150 length but only 
up to 4mm 
 CSI diamond back has 137-143 working length 
 Unless working on Mickey and Minnie limited

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Coppola J - AIMRADIAL 2014 Endovascular - Iliac and femoral

  • 1. TRANSRADIAL ENDOVASCULAR Iliac and Femoral INTERVENTIONS Chicago AIM R a d i a l 2014 John Coppola NYU Langone Medical Center
  • 2. Overview  1. Why TRA for Endovascular Iliac Interventions?  2. Anthropometric Measurements  Limitations and needs
  • 3. Bleeding 2004-2011 3,386,688 PCIs 1.7% bleeding episodes Increased risk for mortality of 12.1% Chhatriwella JAMA 3/13/2013
  • 4. Radial Artery-Ideal Access Site  Easily accessible even in subjects with severe PVD  Cannulation benefit for most arterial beds (natural blood flow)  Major advantage in terms of bleeding complications1,2  Improved quality of life3  Time-sparing hemostasis  Same-day discharge Kiemeneij F, et al. ACCESS Trial. JACC, 1997 RIVAL Trial. Lancet 2011 Cooper CJ, et al. Am Heart J, 1999
  • 5. ACCUITY - Access Radial (798) Femoral (11988)
  • 6. advantages  Absent or markedly decreased pulse  Difficult to crossover in calcified vessels  “ upside down “V”  Ostial disease on contralateral side  Low external iliac disease  Avoid closure device or compression distal to fresh stent
  • 7. Most patients making radial first My practice
  • 8. How  Use left radial saves crossing arch  Start with short introducer give cocktail  LIMA if wire does not go right into DA always follow passage of wire down to avoid damage to branch vessels of aorta  With exchange wire in DA exchange for long sheath Cook 110 or Terumo 90 cm  Self expanding 5Fr or 6Fr balloon expandable many need 7Fr of “free wire”
  • 9. How  Use long wire for exchange  If 0.014” system viper wire from CSI 360cm can usually use 0.14 exchange wirers  Super core 0.035 300 cm wire
  • 10. Anthropometric measurements Wrist - Subclavian = 50- 65cm L Wrist - Renal A = 90cm L Wrist - Common Iliac = 105-115cm R Wrist - R Carotid = 55-65cm R Wrist - L Carotid (bovine arch) = 55-65cm L Wrist - CFA = 125- 135 cm L Wrist - Popliteal A= 155- 170 cm L Wrist - Foot= 200-230 cm
  • 11. Left Radial Artery vs R-Radial  1. Gain about 5-8 cm  2. Avoid the innominate a. tortuosity  3. Avoid catheter manipulation in the aortic arch
  • 12. TRANSRADIAL for Endovascular Interventions BASIC EQUIPMENT Introducer Sheaths: 5 and 6 Fr 90 cm (Terumo); 110 cm (Cook) Wires: 0.014 / 330 Viper (CSI); 0.035 / 300 Supracor (Abbott); 0.035 hydrophilic coating (Terumo; Cordis) Balloons: up to 5.0 mm diameter - 150 cm shaft (most balloons) 5.5mm and up - longest shaft 135 (Abbott, EV3) Scoring Balloons: Angiosculpt - 5 Fr - up to 6.0 - 137-139cm shaft Cutting Ballons - 6 Fr - 137 cm Stents: the only 5 Fr platform - Zilver stent (Cook) -125cm 6 Fr platform - longest shaft 135 (Abbott)
  • 13. TRANSRADIAL for Endovascular Interventions ADVANCED EQUIPMENT  CTO Devices:  CROSSER (Bard) - 146 cm shaft - 6Fr (14S)  Wildcat (Avinger) 6Fr - 110 cm; 5Fr - 140 cm  Frontrunner (Cordis) - 140 cm  Reentry Devices:  Outback (Cordis) - 6 Fr - 120 cm  Pioneer (Medtronic) - 6 Fr - 120cm  Atherectomy:  DB 360 (CSI) - 146 cm shaft - all crowns fit in 6 Fr (except 2.25mm)  IVUS:  Volcano - 150 cm  Atlantis (Boston Scientific) - 135 cm
  • 14. Iliac Artery Stenting  L radial is preferred (gain aprox 10 cm)  5-6 Fr / 110 cm introducers  Any unilateral angioplasty and stenting can be performed either with 5Fr compatible self-expandable stents (Cook Medical), or balloon expandable stents
  • 15. Iliac Artery Stenting 6 Fr 110cm sheath Post Stenting 330 cm 0.014” Viper wire
  • 16. Transradial Iliac Stenting  80 iliac lesions treated via TRA (28%CTO) or TFA (9% CTO) Conclusions: 1. Similar contrast use (238 vs 213 ml) 2. Similar fluoroscopy time (30 vs 27 min) 1. Shorter time to discharge (14.4 vs 20.9 hrs) 2. Lower access-site complications (0 vs 7.2%) Staniloae et al. Cath Cardiovasc interv 2009
  • 17. CFA Interventions  No stent zone  Frequently - atherectomy + PTA  Most atherectomy devices require 7 Fr introducer sheaths  DB360 - CSI - the only atherectomy device 6 Fr compatible
  • 18. CFA Interventions Left radial access Right CFA occlusion Left CFA occlusion
  • 19. CFA Interventions Shuttle sheath, 6Fr/ 110cm/ 0.087” via left radial access CROSSER 14S Calcified CFA, SFA, PFA
  • 20. CFA Interventions DB 360 - 2.0 SC 30 PTA 6.0 mm balloon
  • 21. CFA Interventions Post PTA 6.0 at 4 atm Residual Calcified Eccentric Stenosis Residual calcified plaque at the bifurcation
  • 22. CFA Interventions Wire in PFA DB 360 SC Final result
  • 23. New Frontiers SFA / Popliteal  Currently - severe limitations do to lack of adequate equipment  Proximal SFA:  PTA  Atherectomy with DB 360 - shaft length 146 cm  Occasionally - stenting (135 cm)
  • 24. Proximal SFA 5 Fr 110 cm sheath Edge restenosis post Viabahn stent Angioscupt 5.0/40
  • 25. Limitations of TRA for Endovascular Interventions  Lack of adequate transradial training  Limited equipment  Paucity of clinical studies
  • 26. Equipment Shortage There is a need for: 1. Larger variety of introducer sheaths (90 / 100 / 110 / 125 cm) 2. Ballon catheters with shaft lenghts up to 170-180 cm 3. Longer Guidewires (360-380cm) 4. Stents with shaft lenghts up to 170-180cm 5. CTO / Reentry devices longer and lower profile
  • 27. SFA  Same procedure as iliac  Devices limited to balloon 150 length but only up to 4mm  CSI diamond back has 137-143 working length  Unless working on Mickey and Minnie limited