The document discusses topics related to medical education at the Rawalpindi Medical University. It covers the university's vision of imparting research-oriented medical education while providing quality patient care. It also discusses laboratory experiments for detecting aromatic amino acids and tyrosine, integrating concepts across disciplines, maintaining ethics in the laboratory, and accessing the digital library for research articles.
The development of Ecohealth and One Health training programs in VietnamILRI
Presentation by Phuc Pham Duc, Tran Thi Tuyet Hanh, Hung Nguyen-Viet, Luu Quoc Toan, Dinh Xuan Tung, Le Vu Anh at the 5th biennial conference of the International Association for Ecology and Health (EcoHealth 2014), Montreal, Canada, 11−15 August 2014.
16_Program Elective course - I (Good lab practies).pdfVamsi kumar
This course "Good Laboratory Practices" will guide the students through the basics of good lab practices, ensuring safety and risk management, delve deeper into quality control and assurance, and finally explore the implementation of these practices in specialized areas like clinical, diagnostic, and research labs. The syllabus will provide a deep understanding of laboratory standard operating procedures, quality improvement cycles, the role of proficiency testing, and the ethical considerations involved in lab practices. Through a series of case studies, students will also be exposed to practical, real-world scenarios where they can apply their theoretical knowledge.
Created by: Mr. Attuluri Vamsi Kumar, Assistant Professor, Department of MLT, UIAHS, Chandigarh University, Mohali, Punjab. For more details website: https://www.mltmaster.com
Harmonization of Approaches for Food Ingredients and Constituents: Is It Poss...Burdock Group Consultants
Presented by Dr. Ray Matulka at IFT15 on Sunday, July 12 at 1:15 PM.
The basic principles of safety can apply to all constituents in foods and beverages whether they are present purposefully or not. However, numerous factors can influence the approaches utilized for hazard characterization and risk assessment for various food and beverage constituents. These factors can include; the regulatory and legal framework being followed, what is and what is not known scientifically about the safety of a constituent, what the substance is and its function in a food or beverage, and consumer perception of the substance in the food or beverage. Simply segregating the safety assessment of compounds found in foods and beverages based how they came to be present in foods and beverages can be problematic for all stakeholders charged with ensuring the safety of foods and beverages. Additionally, food safety organizations around the world have adopted a variety of different approaches for addressing the safety of constituents in foods and beverages, which complicates, rather than simplifies the risk assessment process. The ability to adopt and adapt various scientifically valid approaches for evaluating safety becomes important for ensuring the safety and continuity of supply of foods and beverages. Another important factor that must be considered while evaluating the safety of constituents in food and beverages is communication with the consumer and crafting appropriate messaging demonstrating the rigor of the evaluation with a goal of preserving and promoting trust in the safety of the food and beverage supply.
A presentation delivered by Derick Mitchell, IPPOSI CEO at the event to celebrate International Clinical Trials Day on May 10th, 2018 in the Mansion House, Dublin, organised by HRB-CRCI.
Young pharmaceutical scientists are and can get involved in all aspects of new drug discovery and development. They have to be appropriately qualified, trained and experienced though,
The development of Ecohealth and One Health training programs in VietnamILRI
Presentation by Phuc Pham Duc, Tran Thi Tuyet Hanh, Hung Nguyen-Viet, Luu Quoc Toan, Dinh Xuan Tung, Le Vu Anh at the 5th biennial conference of the International Association for Ecology and Health (EcoHealth 2014), Montreal, Canada, 11−15 August 2014.
16_Program Elective course - I (Good lab practies).pdfVamsi kumar
This course "Good Laboratory Practices" will guide the students through the basics of good lab practices, ensuring safety and risk management, delve deeper into quality control and assurance, and finally explore the implementation of these practices in specialized areas like clinical, diagnostic, and research labs. The syllabus will provide a deep understanding of laboratory standard operating procedures, quality improvement cycles, the role of proficiency testing, and the ethical considerations involved in lab practices. Through a series of case studies, students will also be exposed to practical, real-world scenarios where they can apply their theoretical knowledge.
Created by: Mr. Attuluri Vamsi Kumar, Assistant Professor, Department of MLT, UIAHS, Chandigarh University, Mohali, Punjab. For more details website: https://www.mltmaster.com
Harmonization of Approaches for Food Ingredients and Constituents: Is It Poss...Burdock Group Consultants
Presented by Dr. Ray Matulka at IFT15 on Sunday, July 12 at 1:15 PM.
The basic principles of safety can apply to all constituents in foods and beverages whether they are present purposefully or not. However, numerous factors can influence the approaches utilized for hazard characterization and risk assessment for various food and beverage constituents. These factors can include; the regulatory and legal framework being followed, what is and what is not known scientifically about the safety of a constituent, what the substance is and its function in a food or beverage, and consumer perception of the substance in the food or beverage. Simply segregating the safety assessment of compounds found in foods and beverages based how they came to be present in foods and beverages can be problematic for all stakeholders charged with ensuring the safety of foods and beverages. Additionally, food safety organizations around the world have adopted a variety of different approaches for addressing the safety of constituents in foods and beverages, which complicates, rather than simplifies the risk assessment process. The ability to adopt and adapt various scientifically valid approaches for evaluating safety becomes important for ensuring the safety and continuity of supply of foods and beverages. Another important factor that must be considered while evaluating the safety of constituents in food and beverages is communication with the consumer and crafting appropriate messaging demonstrating the rigor of the evaluation with a goal of preserving and promoting trust in the safety of the food and beverage supply.
A presentation delivered by Derick Mitchell, IPPOSI CEO at the event to celebrate International Clinical Trials Day on May 10th, 2018 in the Mansion House, Dublin, organised by HRB-CRCI.
Young pharmaceutical scientists are and can get involved in all aspects of new drug discovery and development. They have to be appropriately qualified, trained and experienced though,
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- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
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Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
CDSCO and Phamacovigilance {Regulatory body in India}NEHA GUPTA
The Central Drugs Standard Control Organization (CDSCO) is India's national regulatory body for pharmaceuticals and medical devices. Operating under the Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India, the CDSCO is responsible for approving new drugs, conducting clinical trials, setting standards for drugs, controlling the quality of imported drugs, and coordinating the activities of State Drug Control Organizations by providing expert advice.
Pharmacovigilance, on the other hand, is the science and activities related to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems. The primary aim of pharmacovigilance is to ensure the safety and efficacy of medicines, thereby protecting public health.
In India, pharmacovigilance activities are monitored by the Pharmacovigilance Programme of India (PvPI), which works closely with CDSCO to collect, analyze, and act upon data regarding adverse drug reactions (ADRs). Together, they play a critical role in ensuring that the benefits of drugs outweigh their risks, maintaining high standards of patient safety, and promoting the rational use of medicines.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
2. The Rawalpindi Medical University
Motto Vision; The Dream/Tomorrow
• To impart evidence based
research oriented medical
education
• To provide best possible
patient care
• To inculcate the values of
mutual respect and ethical
practice of medicine
3. The Rawalpindi Medical University
MSK-II Module
Skill Lab
Xanthoproteic Test
Millon Nasse’s Test
Biochemistry Dept
4. The Rawalpindi Medical University
Learning Objectives
At the end of this session students will be able to learn
• Purpose and chemical reagents of xanthoproetic and millon
nasses’s test
• To perform chemical test to detect the presence of aromatic
amino acids and tyrosine
• Interpret the findings obtained
5. The Rawalpindi Medical University
ProfessorUmarModel of Integrated Lecture
5
60%
CORE SUBJECT
20%
HORIZONTAL
INTEGRATION
Physiology
biochemistry
8%
VERTICAL
INTEGRATION
Pathology
pharmacology
7%
VERTICAL
INTEGRATION
Clinical
integration
5%
VERTICAL
INTEGRATION
Research,
professionalism
Ethics
Digital library
8. The Rawalpindi Medical University
EXPERIMENT
2ml original solution (egg white)
+ 1ml concentrated HNO3 +mix
till white ppt are formed + heat
for 1min till ppt turn yellow +
cool + add 1ml strong ammonia
solution
OBSERVATION
Deep yellow color will appear in
upper alkaline part
INFERENCE
Aromatic amine acid is detected
Xanthoproteic Test
Core Concept
9. The Rawalpindi Medical University
EXPERIMENT
Take 2ml original solution (
egg white ) + 2 drops conc.
H2SO4 + 2ml of acidic
mercuric sulphate + mix + boil
for 1 min + cool + 1ml NaNO2
+ Heat again
OBSERVATION
Red ppt will appear
INFERENCE
Tyrosine is detected
Millon Nasse’s Test
Core Concept
13. The Rawalpindi Medical University
• Always wear white coat in
lab
• Handle the glassware gently
• Wait for your turn while
working in groups
• Use gloves while handling
chemicals
• Do not waste reagents or
other lab supplies
Lab Ethics
13
14. The Rawalpindi Medical University
• Respect and work in harmony with other
students and members of lab
• Control and prevent contamination in Lab
• Getting to know your lab mates results in
overall healthier relationship, with more
intellectual and emotional support.
• There should be time management and
multitasking
• Maintain Lab etiquettes
Communication Skill
14
15. The Rawalpindi Medical University
Professionalism
• Always wear lab coat
along with Id card
• Never take anything
from your lab that does
not belong to you
• Follow safety
procedures
• Do not eat or drink
during lab working
hours
16. The Rawalpindi Medical University
The principle of beneficence is the obligation of physician
to act for the benefit of the patient and supports a number
of moral rules to protect and defend the right of others,
prevent harm, remove conditions that will cause harm,
help persons with disabilities, and rescue persons in
danger.
It is worth emphasizing that, the language here is one of
positive requirements. The principle calls for not just
avoiding harm, but also to benefit patients and to promote
their welfare.
TAKE HOME
MESSAGE
Vertical
integration
Beneficence
18. The Rawalpindi Medical University
Related Research Article
• https://r.search.yahoo.com/_ylt=AwrijCh7SShk9CgeLIRXNyoA;
_ylu=Y29sbwNiZjEEcG9zAzUEdnRpZANMT0NVSTA5MF8xBHNlY
wNzcg--
/RV=2/RE=1680390651/RO=10/RU=https%3a%2f%2fwww.nat
ure.com%2fsubjects%2fprotein-
analysis%2fsrep/RK=2/RS=9zMx.UbK.1jNkr8pg3VBTN8IaLQ-
19. The Rawalpindi Medical University
Skill Lab Assessment
1. Which of the following factors is not responsible for the
denaturation of proteins?
(a) Heat
(b) Charge
(c) pH change
(d) Organic solvents
2. Which of the following is responsible for specifying the 3D
shape of a protein?
(a) The peptide bond
(b) The amino acid sequence
(c) Interaction with other polypeptides
(d) Interaction with molecular chaperons
20. The Rawalpindi Medical University
3. ________is not a classified form of conjugated proteins.
(a) Lipoproteins
(b) Glycoproteins
(c) Metalloproteins
(d) Complete proteins
4. What is the average molecular weight of an amino acid
residue in a protein?
(a) 120
(b) 110
(c) 130
(d) 140
Skill Lab Assessment
21. The Rawalpindi Medical University
5. Which of the following statements is true about proteins?
(a) Proteins are made up of amino acids.
(b) Proteins are essential for the development of skin, teeth
and bones.
(c) Protein is the only nutrient that can build, repair and
maintain body tissues.
(d) All of the above
Skill Lab Assessment
23. The Rawalpindi Medical University
• Steps to Access HEC Digital Library
1. Go to the website of HEC National Digital Library.
2. On Home Page, click on the INSTITUTES.
3. A page will appear showing the universities from Public
and Private Sector and other Institutes which have access
to HEC National Digital Library HNDL.
4. Select your desired Institute.
5. A page will appear showing the resources of the
institution
6. Journals and Researches will appear
7. You can find a Journal by clicking on JOURNALS AND
DATABASE and enter a keyword to search for your desired
journal.
How To Access Digital Library
24. The Rawalpindi Medical University
Learning Resources
• Journal of Practical Vol-1
• Google images