This document provides guidance on writing proper titles and introductions for research papers. It recommends that titles be concise and informative, between 10-12 words, and avoid clutter words. Good titles adequately describe the paper's contents and capture readers' attention. The introduction should establish the broader topic in step one, indicate a knowledge gap in step two, and state the paper's purpose in step three. Examples of strong and weak titles are also discussed.
Navigating publishing process - from a big idea to a great scientific paper!Milka Kostic
In this presentation I share my advice on how to navigate the process scientists take from having a big idea to publishing their paper, and sharing the excitement about the new findings with the world. This presentation is closely related to the advice I gave in a series of blog posts:
http://crosstalk.cell.com/blog/getting-your-paper-published-with-as-little-frustration-as-possible-1
http://crosstalk.cell.com/blog/getting-your-paper-published-with-as-little-frustration-as-possible-2
http://crosstalk.cell.com/blog/getting-your-paper-published-with-as-little-frustration-as-possible-3
http://crosstalk.cell.com/blog/getting-your-paper-published-with-as-little-frustration-as-possible-4
http://crosstalk.cell.com/blog/getting-your-paper-published-with-as-little-frustration-as-possible-5
http://crosstalk.cell.com/blog/getting-your-paper-published-beyond-the-rule-of-five
IN THIS Presentation will see:
1- WHAT IS AN ABSTRACT
2- FOR WHAT PURPOSES
3- DIFFERENT TYPES OF ABSTRACT
4- WHAT TO INCLUDE
5- WHAT NOT TO INCLUDE
6- SOME EXAMPLES
ThesisProject Guidelines for Graduate Students Acknowle.docxchristalgrieg
Thesis/Project Guidelines
for Graduate Students
Acknowledgement: This guide is an abbreviated and heavily edited version of the MS Thesis Guidelines at the New Castle University in England.
1 Overview
These guidelines are intended to help you in the thesis/project process. Given that a thesis/project is an individual piece of work there is no intention unduly to restrict you in your approach. This document presents guidelines to support your work, therefore, and is not a set of absolute rules or procedures to which you must adhere. You will talk in more detail about your own project with your thesis/project supervisor.
In general, thesis/projects vary in style and approach according to your program of study. The following represent some core principles that differentiate a thesis from a practical project:
· Thesis: You undertake a thorough review of literature and of current knowledge and test the theoretical base for your work in some way in some practical situation. You typically present some hypothesis and test them for validity through some hands-on experiments, surveys or other instruments. The objective is to help the research community.
· Practical Project: You undertake a thorough investigation of a topic (e.g., use of mobile devices in healthcare) and develop deep understanding of the practical aspects and real life applications/implications of the field. You may develop prototypes or insightful reports that are of value to practitioners. The objective is to help the practitioner community.
The primary goal of the thesis/project is to allow you to enrich your knowledge and integrate your academic study with the analysis of related practical or theoretical work. The results produced should be publishable in a conference paper after minor additional work. This is not a requirement, just a desirable goal.
2 Assessment Criteria
2.1. The scope of assessment
Ideally, your thesis/project should reflect:
· A clear statement of the problem you have chosen to investigate
· A thorough reading of the relevant literature (practical or theoretical)
· Appropriate selection of a study approach
· An ability to synthesise various perspectives
· A good grasp of the theoretical and/or practical issues
· An ability to evaluate evidence, drawing appropriate conclusions and acknowledging ambiguity;
· Clarity of presentation
· A fluent style
2.2 How your work is Assessed
The thesis/project will be assessed by your advisor and other relevant experts as determined.
2.3 Presentation and format
Length: The Thesis/project should be between 10,000 to 12,000 words (it should not exceed 12,000 words), not including references and appendices.
You must submit an electronic copy of your work in PDF format.
There are no firm specific rules for content and presentation. However, thesis/projects will normally comprise:
· A Title Page (this is essential): including the title of the thesis/project, your name and degree course, ...
Any student in a high level institution will be usually required to write a variety of dissertations, papers and essays throughout the whole period of their studies.
These writing tasks and assignments will cover a myriad of goals, objectives and purposes.
Navigating publishing process - from a big idea to a great scientific paper!Milka Kostic
In this presentation I share my advice on how to navigate the process scientists take from having a big idea to publishing their paper, and sharing the excitement about the new findings with the world. This presentation is closely related to the advice I gave in a series of blog posts:
http://crosstalk.cell.com/blog/getting-your-paper-published-with-as-little-frustration-as-possible-1
http://crosstalk.cell.com/blog/getting-your-paper-published-with-as-little-frustration-as-possible-2
http://crosstalk.cell.com/blog/getting-your-paper-published-with-as-little-frustration-as-possible-3
http://crosstalk.cell.com/blog/getting-your-paper-published-with-as-little-frustration-as-possible-4
http://crosstalk.cell.com/blog/getting-your-paper-published-with-as-little-frustration-as-possible-5
http://crosstalk.cell.com/blog/getting-your-paper-published-beyond-the-rule-of-five
IN THIS Presentation will see:
1- WHAT IS AN ABSTRACT
2- FOR WHAT PURPOSES
3- DIFFERENT TYPES OF ABSTRACT
4- WHAT TO INCLUDE
5- WHAT NOT TO INCLUDE
6- SOME EXAMPLES
ThesisProject Guidelines for Graduate Students Acknowle.docxchristalgrieg
Thesis/Project Guidelines
for Graduate Students
Acknowledgement: This guide is an abbreviated and heavily edited version of the MS Thesis Guidelines at the New Castle University in England.
1 Overview
These guidelines are intended to help you in the thesis/project process. Given that a thesis/project is an individual piece of work there is no intention unduly to restrict you in your approach. This document presents guidelines to support your work, therefore, and is not a set of absolute rules or procedures to which you must adhere. You will talk in more detail about your own project with your thesis/project supervisor.
In general, thesis/projects vary in style and approach according to your program of study. The following represent some core principles that differentiate a thesis from a practical project:
· Thesis: You undertake a thorough review of literature and of current knowledge and test the theoretical base for your work in some way in some practical situation. You typically present some hypothesis and test them for validity through some hands-on experiments, surveys or other instruments. The objective is to help the research community.
· Practical Project: You undertake a thorough investigation of a topic (e.g., use of mobile devices in healthcare) and develop deep understanding of the practical aspects and real life applications/implications of the field. You may develop prototypes or insightful reports that are of value to practitioners. The objective is to help the practitioner community.
The primary goal of the thesis/project is to allow you to enrich your knowledge and integrate your academic study with the analysis of related practical or theoretical work. The results produced should be publishable in a conference paper after minor additional work. This is not a requirement, just a desirable goal.
2 Assessment Criteria
2.1. The scope of assessment
Ideally, your thesis/project should reflect:
· A clear statement of the problem you have chosen to investigate
· A thorough reading of the relevant literature (practical or theoretical)
· Appropriate selection of a study approach
· An ability to synthesise various perspectives
· A good grasp of the theoretical and/or practical issues
· An ability to evaluate evidence, drawing appropriate conclusions and acknowledging ambiguity;
· Clarity of presentation
· A fluent style
2.2 How your work is Assessed
The thesis/project will be assessed by your advisor and other relevant experts as determined.
2.3 Presentation and format
Length: The Thesis/project should be between 10,000 to 12,000 words (it should not exceed 12,000 words), not including references and appendices.
You must submit an electronic copy of your work in PDF format.
There are no firm specific rules for content and presentation. However, thesis/projects will normally comprise:
· A Title Page (this is essential): including the title of the thesis/project, your name and degree course, ...
Any student in a high level institution will be usually required to write a variety of dissertations, papers and essays throughout the whole period of their studies.
These writing tasks and assignments will cover a myriad of goals, objectives and purposes.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
This presentation explores a brief idea about the structural and functional attributes of nucleotides, the structure and function of genetic materials along with the impact of UV rays and pH upon them.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/
1. Writing Proper Title and
Introduction
Dr. Nermin Ahmed Osman
Assistant Lecturer of Medical Statistics
nerminahmed@alexu.edu.eg
UNSSC Intern – UNITAR
(Royal Statistical Association)
nerminosman@limun.org.uk
7. HOW TO PREPARE THE TITLE
First impressions are strong impressions; a title ought
therefore to be well studied, and to give, so far as its
limits permit, a definite and concise indication of what
is to come. —T. Clifford Allbutt
8.
9.
10. DEFINITION OF A GOODTITLE:
The fewest possible words that adequately describe the
contents of the research work.
•Condenses the paper’s content in a few words
•Captures the readers’ attention
•Differentiates the paper from other papers of the same
subject area
11. LENGTH OF THE TITLE
A good title for a research paper is typically around 10 to 12
words long. A lengthy title may seem unfocused and take
the readers’ attention away from an important point.
12. Do :
1- Keep it concise and informative
2-Write for your audience
3-Be attractive
4-Incorporate important keywords
5-Write in sentence case, try to include your
study design
13. REMOVE THE WASTE WORDS: (CLUTTER)
•"Studies on ''
• "Investigations on''
•"Observations on"
14. Do not:
1- Exaggerate (Do not use dramatic title)
2- Write your title as a question
You have to use an indicative
or conclusive title
Because you already got the answer of your research hypothesis
18. Drug XYZ has an reliving effect on muscular
spasm for athletics
Drug XYZ reduces muscular spasm for
athletics
19. COMMENT ON THE FOLLOWING TITLE:
"Action of Various Antifungal Antibiotics on Candida
albicans and Aspergillus fumigatus”
Not Specific
20. COMMENT ON THE FOLLOWING TITLE:
"Isolation of Antigens from Rats Using CF technique”
Jargon/Vague
21. CHOOSE THE BEST ONE :
•"Action of Streptomycin on Mycobacterium tuberculosis"
• "Inhibition of Growth of Mycobacterium tuberculosis by
Streptomycin."
31. STEP 1:ESTABLISHING A TERRITORY
nerminahmed@alexu.edu.eg
In this opening step, the author may do one or more of the following to
broadly sketch out where the subject of his/her essay falls—the “big picture”
• ·
•·
Or
Point out the main topic and its importance. Make
generalizations about the subject
Review items of previous research. (( Current Knowledge))
(( Literature Review)) ((
Background))
32. STEP 2:ESTABLISHING A NICHE
nerminahmed@alexu.edu.eg
(Niche = knowledge gap)
In this step, the author takes the reader to a particular area of the broader
subject that the essay will deal with. This can be done using one or more of the
following:
• · Make a counter-claim, i.e. assert something contrary to expectations
• · Indicate a gap in the existing research/thinking
• · Raise a question about existing research/thinking
• · Suggest the essay is continuing a tradition, i.e. it is following in the
footsteps of previous research/thinking
33. STEP 3:OCCUPYING THE NICHE
• In this step, the author Outlines the purpose of the essay, or state the
research that was pursued.
Aim of the work
nerminahmed@alexu.edu.eg