The document discusses coprocessing of pharmaceutical excipients. Coprocessing involves physically modifying existing excipients to create new multifunctional excipients. This can overcome limitations of individual excipients and replace the need for multiple excipients. The advantages are improved flowability, compressibility and tablet properties. However, the ratio of initial excipients is fixed, which may limit compatibility. Overall, coprocessing combines benefits of wet granulation and direct compression tablet manufacturing.