Fallopian tube blockagIVFe is a condition where one or both of the fallopian tubes are obstructed, hindering the passage of eggs from the ovaries to the uterus.
Blocked Fallopian Tubes- When Is Laparoscopic Surgery the Answer.pptxFFragrant
Women with blocked fallopian tubes may need surgery when they have severe cndition. Women can sldo choose herbal medicine Fuyan Pill when they have mild condition.
Infertility treatment by a gynecologist involves a range of approaches to help couples conceive. This may include hormonal therapy to regulate ovulation, surgical procedures to address anatomical issues, or assisted reproductive technologies like in vitro fertilization (IVF). Gynecologists also provide counseling and support to navigate emotional and psychological aspects of infertility, guiding patients towards the most suitable treatment options.
Miracles IVF & Fertility Clinic is known for its ethical and international standard fertility treatment. With experienced fertility specialists, we have been able to maintain consistently high success rate and this made us the most preferred fertility clinic in Gurgaon for childless couples.
In vitro fertilization (IVF) is a form of assisted reproductive technology that can help couples overcome infertility and conceive a child. IVF involves combining an egg and sperm outside the body in a laboratory dish and then transferring the resulting embryo into the woman's uterus. IVF can be an effective treatment option for a variety of infertility issues. In this article, we'll explore some of the causes of infertility that IVF treatment in Dubai can treat.
Visit here for more: https://drmazenivf.com/ivf-treatment-in-dubai/
An MBBS, MD, D.A.G.E (Germany), Dr. Khanna was born and brought up in Delhi in a family of freedom fighters and doctors. An alumni of Delhi Public School, RK Puram, and Medical College Baroda, she was a topper throughout her school and college education. She served as Senior Consultant at Sri Balaji Action Medical Institute from Year 2002 to Year 2011. Besides this Dr. Manika is a recipient of the Delhi Ratan Award (2008) and a Lifetime Member of the American Society of Reproductive Medicine. Apart from being an acclaimed IVF specialist, Dr. Khanna is a philanthropist at heart, actively involved in several support programs for the underprivileged.
The document discusses infertility, including its definition, causes, risk factors, diagnostic evaluation, management, and prevention. Infertility is defined as the failure to conceive after one year of unprotected intercourse. It can be caused by issues with ovulation, fallopian tubes, or the uterus. Diagnostic evaluations include medical history, exams, and tests of hormones and reproductive organs. Treatments include fertility drugs, surgery, intrauterine insemination (IUI), in vitro fertilization (IVF), and other assisted reproductive technologies (ART). Prevention focuses on maintaining a healthy lifestyle and treating existing diseases early.
The document discusses the causes and treatment of female infertility. It outlines various causative factors including problems with the fallopian tubes, ovulation, endometriosis, cervical or uterine issues, and other behavioral and environmental factors. Diagnostic tests like hysterosalpingography and laparoscopy are used to identify issues. Treatments include fertility drugs to stimulate ovulation, surgery to repair damaged tubes, and IVF which involves retrieving eggs, fertilizing them with sperm in vitro, and transferring embryos into the uterus. Maintaining a healthy lifestyle, treating existing diseases, and not delaying parenthood can help prevent some cases of infertility.
Fallopian tube blockagIVFe is a condition where one or both of the fallopian tubes are obstructed, hindering the passage of eggs from the ovaries to the uterus.
Blocked Fallopian Tubes- When Is Laparoscopic Surgery the Answer.pptxFFragrant
Women with blocked fallopian tubes may need surgery when they have severe cndition. Women can sldo choose herbal medicine Fuyan Pill when they have mild condition.
Infertility treatment by a gynecologist involves a range of approaches to help couples conceive. This may include hormonal therapy to regulate ovulation, surgical procedures to address anatomical issues, or assisted reproductive technologies like in vitro fertilization (IVF). Gynecologists also provide counseling and support to navigate emotional and psychological aspects of infertility, guiding patients towards the most suitable treatment options.
Miracles IVF & Fertility Clinic is known for its ethical and international standard fertility treatment. With experienced fertility specialists, we have been able to maintain consistently high success rate and this made us the most preferred fertility clinic in Gurgaon for childless couples.
In vitro fertilization (IVF) is a form of assisted reproductive technology that can help couples overcome infertility and conceive a child. IVF involves combining an egg and sperm outside the body in a laboratory dish and then transferring the resulting embryo into the woman's uterus. IVF can be an effective treatment option for a variety of infertility issues. In this article, we'll explore some of the causes of infertility that IVF treatment in Dubai can treat.
Visit here for more: https://drmazenivf.com/ivf-treatment-in-dubai/
An MBBS, MD, D.A.G.E (Germany), Dr. Khanna was born and brought up in Delhi in a family of freedom fighters and doctors. An alumni of Delhi Public School, RK Puram, and Medical College Baroda, she was a topper throughout her school and college education. She served as Senior Consultant at Sri Balaji Action Medical Institute from Year 2002 to Year 2011. Besides this Dr. Manika is a recipient of the Delhi Ratan Award (2008) and a Lifetime Member of the American Society of Reproductive Medicine. Apart from being an acclaimed IVF specialist, Dr. Khanna is a philanthropist at heart, actively involved in several support programs for the underprivileged.
The document discusses infertility, including its definition, causes, risk factors, diagnostic evaluation, management, and prevention. Infertility is defined as the failure to conceive after one year of unprotected intercourse. It can be caused by issues with ovulation, fallopian tubes, or the uterus. Diagnostic evaluations include medical history, exams, and tests of hormones and reproductive organs. Treatments include fertility drugs, surgery, intrauterine insemination (IUI), in vitro fertilization (IVF), and other assisted reproductive technologies (ART). Prevention focuses on maintaining a healthy lifestyle and treating existing diseases early.
The document discusses the causes and treatment of female infertility. It outlines various causative factors including problems with the fallopian tubes, ovulation, endometriosis, cervical or uterine issues, and other behavioral and environmental factors. Diagnostic tests like hysterosalpingography and laparoscopy are used to identify issues. Treatments include fertility drugs to stimulate ovulation, surgery to repair damaged tubes, and IVF which involves retrieving eggs, fertilizing them with sperm in vitro, and transferring embryos into the uterus. Maintaining a healthy lifestyle, treating existing diseases, and not delaying parenthood can help prevent some cases of infertility.
Although its original objective was to treat women with tubal disease, in-vitro fertilization (IVF) can assist couples get rid of different types of the inability to conceive. For some medical diagnoses or problems, such as tubal aspect, IVF might be the first-line therapy. In various other instances, IVF may be suggested only if easier treatment fails.
Raipur Fertility Research Center and ivf is a renowned ICSI treatment centre in India,icsi treatment in Raipur, ICSI success rate in Chhattisgarh , get low cost ICSI treatment with high success Rate in Raipur, Bhilai, Durg, Bilaspur, Bihar, Jharkhand, Jamshedpur, Ranchi, Patna, Orissa, India,Get more info from Raipur IVF
Can Women With Blocked Fallopian Tubes Leave Sequela after Surgical Treatment?FFragrant
The document discusses blocked fallopian tubes and surgical treatment options. It notes that blocked fallopian tubes are a major cause of infertility as they prevent eggs and sperm from meeting. Surgery is often needed to unblock tubes, but it can leave aftereffects depending on the patient and procedure. Potential aftereffects include pain, abdominal distension, infection, and disrupted tubal function. Traditional Chinese herbal medicine may help address aftereffects and prevent reblockage.
No Chance of Pregnancy If the Fallopian Tube Is Blocked? Absolutely NoFFragrant
Fallopian tube blockages can impact fertility but may not prevent pregnancy entirely. While a blockage in one tube reduces the chances of pregnancy, it is still possible if the other tube is not blocked. The level of blockage affects fertility - minor blockages can often be treated surgically while more severe cases are more difficult to treat. Traditional Chinese medicines may help increase fertility for some patients with fallopian tube problems. Overall, pregnancy may still be possible depending on the individual circumstances, so patients should seek medical evaluation and treatment before losing hope of conceiving.
Assisted reproductive technology (ART) refers to various medical techniques used to help with fertility and conception, including in vitro fertilization (IVF), artificial insemination (AI), and surrogacy. Infertility, which affects up to 15% of couples, can be caused by factors in either partner such as sexually transmitted diseases, obesity, genetic defects, or damage to the reproductive organs. IVF involves fertilizing an egg outside the body in a laboratory and then transferring the embryo to the uterus, while AI involves inserting sperm directly into the uterus or fallopian tubes. Surrogacy involves a contracted woman carrying and delivering a baby for an infertile couple. Though ART has enabled successful pregnancies for many, there are
Can Normal Ovulation Indicate Your Fallopian Tubes Are Unobstructed?FFragrant
Women can have normal ovulation whether they have blocked fallopian tubes or not. And herbal medicine Fuyan Pill can treat blocked fallopian tubes and help pregnancy.
This document discusses infertility, including its definition, causes, diagnostic evaluation, and management. It notes that infertility is defined as the inability to conceive after one year of unprotected intercourse. The causes of infertility can be male factors related to sperm production or transport, female factors related to ovulation or egg/hormone problems, or combined factors in both partners. Diagnostic evaluation involves medical histories, physical exams, sperm analysis, hormone testing, imaging of reproductive organs, and other tests to identify treatable causes. Management depends on the underlying causes and may include lifestyle changes, surgery, assisted reproductive technologies like IVF, or alternatives to childbirth like adoption.
Conceiving with a Single Fallopian Tube- Challenges and Strategies for Succes...FFragrant
The document discusses the impact of having a single fallopian tube on fertility. It notes that while fertility is reduced, pregnancy is still possible with one tube. Specifically:
- Having one fallopian tube reduces the chances of conception by about 50% compared to two tubes, as only one tube can capture eggs from the ovaries.
- It's important to ensure the remaining tube is healthy, through tests to check for blockages or other issues that could impact fertility or risk another ectopic pregnancy.
- With strategies like confirming the remaining tube is functional, understanding ovulation patterns, adopting a healthy lifestyle, and managing stress, women with one fallopian tube can still aim for successful pregnancy.
Female infertility is a common issue where a woman is incapable of conceiving and bearing a successful pregnancy. Infertility is a condition that impairs or restricts a person's capacity to get pregnant and give birth to a newborn.
IVF refers to a procedure where the woman's eggs are far away from her ovaries and fertilized with the man's spermatozoon during a laboratory. The embryos fashioned area unit then surrogate into the womb to realize a physiological condition.
Are Fallopian Tubes Open to Women Without Pregnancy?LeoPearson
Whether the fallopian tube is open usually has nothing to do with pregnancy. Once your falloapin tubes are blocked, seek herbal medicine Fuyan Pill for treatment.
IVF involves fertilizing eggs with sperm in a lab and then transferring the embryos into the uterus. It is the most common form of assisted reproductive technology. The IVF process typically involves ovarian stimulation with fertility drugs, egg retrieval, fertilization, embryo culture, and embryo transfer. Success rates vary depending on factors like the age of the woman but on average are around 40% for women under 35. IVF can enable pregnancy for issues like blocked tubes, low egg quality, or male factor infertility but it is a costly and time-intensive process.
IVF involves fertilizing eggs with sperm in a lab and then transferring the embryos into the uterus. It is the most common form of assisted reproductive technology. The IVF process typically involves ovarian stimulation with fertility drugs, egg retrieval, fertilization, embryo culture, and embryo transfer. Success rates vary depending on factors like the woman's age but are around 40% for women aged 34 and under. IVF can cost $12,400 on average per cycle in the US.
This document discusses various medically assisted reproductive technologies used to treat infertility, including intrauterine insemination (IUI), in vitro fertilization (IVF), gamete intrafallopian transfer (GIFT), zygote intrafallopian transfer (ZIFT), tubal embryo stage transfer (TET), and intracytoplasmic sperm injection (ICSI). It provides details on the general protocols and advantages and disadvantages of each technique. Causes of infertility and negative aspects of assisted reproductive technologies are also addressed.
IVF, or in vitro fertilization, is a medical procedure
used to help individuals or couples with fertility issues
conceive a child. It is one of the most well-known and
widely used assisted reproductive technologies (ART).
Although its original objective was to treat women with tubal disease, in-vitro fertilization (IVF) can assist couples get rid of different types of the inability to conceive. For some medical diagnoses or problems, such as tubal aspect, IVF might be the first-line therapy. In various other instances, IVF may be suggested only if easier treatment fails.
Raipur Fertility Research Center and ivf is a renowned ICSI treatment centre in India,icsi treatment in Raipur, ICSI success rate in Chhattisgarh , get low cost ICSI treatment with high success Rate in Raipur, Bhilai, Durg, Bilaspur, Bihar, Jharkhand, Jamshedpur, Ranchi, Patna, Orissa, India,Get more info from Raipur IVF
Can Women With Blocked Fallopian Tubes Leave Sequela after Surgical Treatment?FFragrant
The document discusses blocked fallopian tubes and surgical treatment options. It notes that blocked fallopian tubes are a major cause of infertility as they prevent eggs and sperm from meeting. Surgery is often needed to unblock tubes, but it can leave aftereffects depending on the patient and procedure. Potential aftereffects include pain, abdominal distension, infection, and disrupted tubal function. Traditional Chinese herbal medicine may help address aftereffects and prevent reblockage.
No Chance of Pregnancy If the Fallopian Tube Is Blocked? Absolutely NoFFragrant
Fallopian tube blockages can impact fertility but may not prevent pregnancy entirely. While a blockage in one tube reduces the chances of pregnancy, it is still possible if the other tube is not blocked. The level of blockage affects fertility - minor blockages can often be treated surgically while more severe cases are more difficult to treat. Traditional Chinese medicines may help increase fertility for some patients with fallopian tube problems. Overall, pregnancy may still be possible depending on the individual circumstances, so patients should seek medical evaluation and treatment before losing hope of conceiving.
Assisted reproductive technology (ART) refers to various medical techniques used to help with fertility and conception, including in vitro fertilization (IVF), artificial insemination (AI), and surrogacy. Infertility, which affects up to 15% of couples, can be caused by factors in either partner such as sexually transmitted diseases, obesity, genetic defects, or damage to the reproductive organs. IVF involves fertilizing an egg outside the body in a laboratory and then transferring the embryo to the uterus, while AI involves inserting sperm directly into the uterus or fallopian tubes. Surrogacy involves a contracted woman carrying and delivering a baby for an infertile couple. Though ART has enabled successful pregnancies for many, there are
Can Normal Ovulation Indicate Your Fallopian Tubes Are Unobstructed?FFragrant
Women can have normal ovulation whether they have blocked fallopian tubes or not. And herbal medicine Fuyan Pill can treat blocked fallopian tubes and help pregnancy.
This document discusses infertility, including its definition, causes, diagnostic evaluation, and management. It notes that infertility is defined as the inability to conceive after one year of unprotected intercourse. The causes of infertility can be male factors related to sperm production or transport, female factors related to ovulation or egg/hormone problems, or combined factors in both partners. Diagnostic evaluation involves medical histories, physical exams, sperm analysis, hormone testing, imaging of reproductive organs, and other tests to identify treatable causes. Management depends on the underlying causes and may include lifestyle changes, surgery, assisted reproductive technologies like IVF, or alternatives to childbirth like adoption.
Conceiving with a Single Fallopian Tube- Challenges and Strategies for Succes...FFragrant
The document discusses the impact of having a single fallopian tube on fertility. It notes that while fertility is reduced, pregnancy is still possible with one tube. Specifically:
- Having one fallopian tube reduces the chances of conception by about 50% compared to two tubes, as only one tube can capture eggs from the ovaries.
- It's important to ensure the remaining tube is healthy, through tests to check for blockages or other issues that could impact fertility or risk another ectopic pregnancy.
- With strategies like confirming the remaining tube is functional, understanding ovulation patterns, adopting a healthy lifestyle, and managing stress, women with one fallopian tube can still aim for successful pregnancy.
Female infertility is a common issue where a woman is incapable of conceiving and bearing a successful pregnancy. Infertility is a condition that impairs or restricts a person's capacity to get pregnant and give birth to a newborn.
IVF refers to a procedure where the woman's eggs are far away from her ovaries and fertilized with the man's spermatozoon during a laboratory. The embryos fashioned area unit then surrogate into the womb to realize a physiological condition.
Are Fallopian Tubes Open to Women Without Pregnancy?LeoPearson
Whether the fallopian tube is open usually has nothing to do with pregnancy. Once your falloapin tubes are blocked, seek herbal medicine Fuyan Pill for treatment.
IVF involves fertilizing eggs with sperm in a lab and then transferring the embryos into the uterus. It is the most common form of assisted reproductive technology. The IVF process typically involves ovarian stimulation with fertility drugs, egg retrieval, fertilization, embryo culture, and embryo transfer. Success rates vary depending on factors like the age of the woman but on average are around 40% for women under 35. IVF can enable pregnancy for issues like blocked tubes, low egg quality, or male factor infertility but it is a costly and time-intensive process.
IVF involves fertilizing eggs with sperm in a lab and then transferring the embryos into the uterus. It is the most common form of assisted reproductive technology. The IVF process typically involves ovarian stimulation with fertility drugs, egg retrieval, fertilization, embryo culture, and embryo transfer. Success rates vary depending on factors like the woman's age but are around 40% for women aged 34 and under. IVF can cost $12,400 on average per cycle in the US.
This document discusses various medically assisted reproductive technologies used to treat infertility, including intrauterine insemination (IUI), in vitro fertilization (IVF), gamete intrafallopian transfer (GIFT), zygote intrafallopian transfer (ZIFT), tubal embryo stage transfer (TET), and intracytoplasmic sperm injection (ICSI). It provides details on the general protocols and advantages and disadvantages of each technique. Causes of infertility and negative aspects of assisted reproductive technologies are also addressed.
IVF, or in vitro fertilization, is a medical procedure
used to help individuals or couples with fertility issues
conceive a child. It is one of the most well-known and
widely used assisted reproductive technologies (ART).
Similar to Why Many Women Choose IVF for Blocked Fallopian Tubes.pptx (20)
Understanding the Relationship- Endometriosis and Ovarian Cancer.pptxFFragrant
Endometriosis rarely cause ovarian cancer. However, it can bring many harms to women. Generally, women can seek herbal medicine Fuyan Pill to get a cure.
Managing Adenomyosis- Optimal Duration for Short-Acting Contraceptive Pills.pptxFFragrant
Adenomyosis needs lonig-time managment. And herbal medicine Fuyan Pill should be more effective than short-acting contraceptive pills due to its fewer side effects.
Adenomyosis Beast- When Short-Acting Contraceptives Become Your Ally.pptxFFragrant
Patients with adenomyosis can take short-acting contraceptives to relieve symptoms. And they can select herbal medicine Fuyan Pill without side effects.
Preparing for Pregnancy? Beware of These 3 Factors Linked to Blocked Fallopia...FFragrant
Women should notice 3 factors linked to blocked fallopian tubes when preparing for pregnancy. And they can choose herbal medicine Fuyan Pill to achieve positive results.
10 Benefits an EPCR Software should Bring to EMS Organizations Traumasoft LLC
The benefits of an ePCR solution should extend to the whole EMS organization, not just certain groups of people or certain departments. It should provide more than just a form for entering and a database for storing information. It should also include a workflow of how information is communicated, used and stored across the entire organization.
Travel vaccination in Manchester offers comprehensive immunization services for individuals planning international trips. Expert healthcare providers administer vaccines tailored to your destination, ensuring you stay protected against various diseases. Conveniently located clinics and flexible appointment options make it easy to get the necessary shots before your journey. Stay healthy and travel with confidence by getting vaccinated in Manchester. Visit us: www.nxhealthcare.co.uk
Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
Promoting Wellbeing - Applied Social Psychology - Psychology SuperNotesPsychoTech Services
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Osteoporosis - Definition , Evaluation and Management .pdfJim Jacob Roy
Osteoporosis is an increasing cause of morbidity among the elderly.
In this document , a brief outline of osteoporosis is given , including the risk factors of osteoporosis fractures , the indications for testing bone mineral density and the management of osteoporosis
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Mercurius is named after the roman god mercurius, the god of trade and science. The planet mercurius is named after the same god. Mercurius is sometimes called hydrargyrum, means ‘watery silver’. Its shine and colour are very similar to silver, but mercury is a fluid at room temperatures. The name quick silver is a translation of hydrargyrum, where the word quick describes its tendency to scatter away in all directions.
The droplets have a tendency to conglomerate to one big mass, but on being shaken they fall apart into countless little droplets again. It is used to ignite explosives, like mercury fulminate, the explosive character is one of its general themes.
2. Blocked fallopian tubes are a common cause of
infertility, preventing the egg from reaching the
uterus and hindering fertilization. This condition
can arise from infections, injuries, inflammation, or
pelvic adhesions, leading to partial or complete
blockages.
3. In Vitro Fertilization (IVF) is an advanced
reproductive technology that offers hope to those
unable to conceive naturally due to fallopian tube
issues. When the fallopian tubes are blocked, eggs
and sperm cannot meet, resulting in reduced
chances of natural conception or infertility.
4. IVF circumvents this problem by combining sperm
and eggs outside the body and implanting the
fertilized embryo directly into the woman's uterus.
IVF is not only a solution for fallopian tube
blockages but also addresses other infertility issues,
such as poor sperm quality in men and abnormal
ovulation in women.
5. 1. Tubal Inflammation: Inflammation can narrow the fallopian
tube lumen, cause adhesions, or disrupt normal peristalsis,
hindering the transportation of eggs.
2. Congenital Tubal Hypoplasia: Congenital defects, such as
slim distortions or dysfunctions, can cause blockages.
3. Endometriosis: This condition can alter the pelvic
environment, leading to chronic inflammation, tubal
adhesions, or blockages.
6. While IVF is a common solution, surgical treatments may also be
viable depending on the blockage's cause:
- Inflammation-Based Blockage: Patients might consider
treatments like the Fuyan Pill, effective for gynecological
diseases caused by inflammation.
- External Tissue Damage: Fallopian tube reconstruction surgery
can repair damaged tubes and restore connectivity.
7. IVF bypasses the fallopian tubes entirely, ensuring
eggs reach the uterus. Surgical treatments can
remove inflammatory tissue, blood clots, or stents
blocking the tubes. Procedures like
hysterosalpingography, fallopian tube guidewire,
and hysteroscopy can also aid in achieving
pregnancy.
8. Patients diagnosed with blocked fallopian tubes often
need laparoscopic or hysteroscopy examinations.
Treatment varies based on blockage severity,
including proximal or distal obstructions or
hydrosalpinx (fluid accumulation in the tube).
9. Hydrosalpinx requires special attention, as
accumulated fluid can impact embryo
implantation and reduce IVF success rates. In such
cases, ligating the fallopian tubes or removing the
hydrosalpinx may be necessary before proceeding
with IVF.
10. IVF is a powerful option for those facing infertility due to
blocked fallopian tubes. It offers a way to bypass the physical
barriers preventing natural conception, providing a viable path to
parenthood. However, other treatments and surgical options may
also be considered based on individual diagnoses and conditions.
Consulting with a fertility specialist can help determine the best
approach to overcoming infertility and achieving the dream of
parenthood.
11. If you have questions about your condition
and treatment, contact our experts. Most
questions are answered in 24 hours.
wuhandrli@gmail.com
herbalistlee@yahoo.com
wuhandrlee@hotmail.com