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WHOLE GENOMIC SEQUENCING
A VISION FROM URUGUAY
Dra. Ana María Maquieira
amaqui@latu.org.uy
LATU –URUGUAY
• Surface: 175.016 km2
• Population: 3,286,314
URUGUAY - GENERAL INFORMATION
Economy is based
on Agricultural
production :
LATU - TECHNOLOGICAL LABORATORY OF URUGUAY
LATU - TECHNOLOGICAL LABORATORY OF URUGUAY
HOW DOES FOOD SAFETY MANAGMENT
WORK IN URUGUAY?
FOOD SAFETY MANAGMENT -DIFFERENT ACTORS :
PUBLIC HEALTH
MINISTERY (MSP)
Epidemiology
Sanitary police
MINISTERY OF
LIVESTOCK,AGRICULTURE
AND FISH (MGAP)
INAC
REGIONAL
GOVERNMENT
(RG)
LATU
MSP LAB
School of
Medicine (UDELAR)
- Hygiene Institute
DILAVE
(MGAP LAB)
Authorized
laboratories
RG Food LAB
Normas Nacionales: MSP, MGAP, INAC, Intendencias, LATU.
Leyes :
Ley Orgánica 9202 del 12/01/1934: MSP policía higiénica de los alimentos
Ley 3606/13/04/1910 : MGAP Policía Sanitaria en Sanidad Animal
Decretos:
Decreto 315/994 – Reglamento Bromatológico Nacional
Decreto 338/82: LATU verificación conformidad de alimentos industrializados
importados (menos pesca y piensos)
Decreto 368/000: MGAP Autoridad Sanitaria Oficial de leche y productos lácteos
Decreto 360/003; 576/009 y Resolución 11ª/2010: MGAP Plan Nac. De Residuos
Biológicos.
Decreto 2/997; 20/998; 177/004 y 135/005: MGAP Condiciones de Higiene para
Tambos
TRAZABILIDAD - Ley 17.997 (2006)
Ordenanzas Municipales
Food Regulations - examples
National situation
Foodborne diseases
Distribution of the foodborne diseases outbreaks reported (1993-2014,
Graciela Naviliat MSP - 2014)
N
Distribution of outbreaks of ETA by etiological agent (2014) Sepi 45
(Graciela Naviliat MSP)
SWOT – FODA
WGS
STRENGTHSSmall country:
• Our longest distance is 665 kms
• “We know each other” on food safety.
• Possibility of sharing resources.
Knowledge:
• Training on this topic is actually developing (ex.
Masters in Bioinformatics- Science University)
• Research groups working on sequencing (Instituto
Pasteur and Clemente)
Regulations:
• There is a national code on diseases and health
reportable events
• Existence of an Integrated Health System.
Evento de
Notificación Obligatoria
Notification must be performed
within the first 24 h
( “A Group” of the Reportable
Mandatory Diseases Code, 2012)
to the Surveillance Department of
the Ministry of Public Health.
Tel: 2 409-12-00.
Fax: 2 408-58-38 o al e-mail:
vigilanciaepi@msp.gub.uy
on line system
www.msp.gub.uy
OPPORTUNITIES
• Knowledge of the sourranding flora’s
characteristics.
• Use of an advanced methodology.
• Possibility of deeper epidemiology studies .
• Improvements on chain production.
WEAKNESSESNetworks:
• Weakness in scientists institution´s networks
• Food Safety Authorities` networks need
strengthening.
Knowledge:
• No shared information, food safety data not easily
available .
• Fragmented information, it´s generated only in
especific areas, difficulty in traceabiliy.
• Therefore , information is poor at the moment of
decision making (regulations, risk assessment ,etc.)
Economic resources:
• Resources needed for equipment, training and
supplies.
• Training of teams in data processing.
WEAKNESSES
Epidemiology:
• Inmature epidemiology system in food area.
• Underreporting
• Poorly defined reportable diseases
Methodology
• Need for further development on WGS for use in
food testing (no need of strain isolation).
TREATHS• High cost.
• Need of training on the methodology
• Not all the authorities know about WGS
methodology.
• Low undersatnding of the usefullness of WGS.
• “NASA” methodology – “A Ferrari in a stone street”
• Confidence in the use of databases.
• Fear of trade barriers.
THANK YOU/MUCHAS GRACIAS

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Whole Genome Sequencing (WGS) for food safety management: A vision from Uruguay

  • 1. WHOLE GENOMIC SEQUENCING A VISION FROM URUGUAY Dra. Ana María Maquieira amaqui@latu.org.uy LATU –URUGUAY
  • 2. • Surface: 175.016 km2 • Population: 3,286,314 URUGUAY - GENERAL INFORMATION
  • 3. Economy is based on Agricultural production :
  • 4. LATU - TECHNOLOGICAL LABORATORY OF URUGUAY
  • 5. LATU - TECHNOLOGICAL LABORATORY OF URUGUAY
  • 6. HOW DOES FOOD SAFETY MANAGMENT WORK IN URUGUAY?
  • 7. FOOD SAFETY MANAGMENT -DIFFERENT ACTORS : PUBLIC HEALTH MINISTERY (MSP) Epidemiology Sanitary police MINISTERY OF LIVESTOCK,AGRICULTURE AND FISH (MGAP) INAC REGIONAL GOVERNMENT (RG) LATU MSP LAB School of Medicine (UDELAR) - Hygiene Institute DILAVE (MGAP LAB) Authorized laboratories RG Food LAB
  • 8. Normas Nacionales: MSP, MGAP, INAC, Intendencias, LATU. Leyes : Ley Orgánica 9202 del 12/01/1934: MSP policía higiénica de los alimentos Ley 3606/13/04/1910 : MGAP Policía Sanitaria en Sanidad Animal Decretos: Decreto 315/994 – Reglamento Bromatológico Nacional Decreto 338/82: LATU verificación conformidad de alimentos industrializados importados (menos pesca y piensos) Decreto 368/000: MGAP Autoridad Sanitaria Oficial de leche y productos lácteos Decreto 360/003; 576/009 y Resolución 11ª/2010: MGAP Plan Nac. De Residuos Biológicos. Decreto 2/997; 20/998; 177/004 y 135/005: MGAP Condiciones de Higiene para Tambos TRAZABILIDAD - Ley 17.997 (2006) Ordenanzas Municipales Food Regulations - examples
  • 10. Distribution of the foodborne diseases outbreaks reported (1993-2014, Graciela Naviliat MSP - 2014) N
  • 11. Distribution of outbreaks of ETA by etiological agent (2014) Sepi 45 (Graciela Naviliat MSP)
  • 13. STRENGTHSSmall country: • Our longest distance is 665 kms • “We know each other” on food safety. • Possibility of sharing resources. Knowledge: • Training on this topic is actually developing (ex. Masters in Bioinformatics- Science University) • Research groups working on sequencing (Instituto Pasteur and Clemente) Regulations: • There is a national code on diseases and health reportable events • Existence of an Integrated Health System.
  • 14. Evento de Notificación Obligatoria Notification must be performed within the first 24 h ( “A Group” of the Reportable Mandatory Diseases Code, 2012) to the Surveillance Department of the Ministry of Public Health. Tel: 2 409-12-00. Fax: 2 408-58-38 o al e-mail: vigilanciaepi@msp.gub.uy on line system www.msp.gub.uy
  • 15. OPPORTUNITIES • Knowledge of the sourranding flora’s characteristics. • Use of an advanced methodology. • Possibility of deeper epidemiology studies . • Improvements on chain production.
  • 16. WEAKNESSESNetworks: • Weakness in scientists institution´s networks • Food Safety Authorities` networks need strengthening. Knowledge: • No shared information, food safety data not easily available . • Fragmented information, it´s generated only in especific areas, difficulty in traceabiliy. • Therefore , information is poor at the moment of decision making (regulations, risk assessment ,etc.) Economic resources: • Resources needed for equipment, training and supplies. • Training of teams in data processing.
  • 17. WEAKNESSES Epidemiology: • Inmature epidemiology system in food area. • Underreporting • Poorly defined reportable diseases Methodology • Need for further development on WGS for use in food testing (no need of strain isolation).
  • 18. TREATHS• High cost. • Need of training on the methodology • Not all the authorities know about WGS methodology. • Low undersatnding of the usefullness of WGS. • “NASA” methodology – “A Ferrari in a stone street” • Confidence in the use of databases. • Fear of trade barriers.