Domain-driven design (DDD) is a software development approach that focuses on the core domain and business logic. It proposes a ubiquitous language between business experts and developers. DDD is useful for complex domains with many business rules and an iterative development process. It aims to produce software that is flexible, extensible and has testable code agreed upon by domain experts and developers. Key aspects of DDD include modeling the domain using entities, value objects, aggregates and repositories. Other patterns like factories, services and commands can also be used. CQRS separates reads from writes for flexibility and performance. Frameworks like ORM, dependency injection and UUIDs can help implement DDD in PHP applications.