Wojciech Sznapka presents key principles for achieving wise architecture with Symfony2:
1. Follow SOLID principles - each component should have a single responsibility and dependencies should be injected through interfaces.
2. Prioritize maintainability - thoroughly test code and implement logging.
3. Design for scalability - avoid dependencies on local storage, scale the database, and optimize for horizontal scaling.
Wise architecture is achieved by following best practices, leveraging existing bundles, and ensuring the application can be easily maintained and scaled over time.