The Institute for Industrial Research & Toxicology (IIRT) is a multi-disciplinary contract research organization established in 2007 that provides laboratory testing services for agrochemicals, pharmaceuticals, and other products. IIRT has specialized facilities for small animal research, analytical testing, and toxicology studies. It conducts a variety of tests, including acute toxicity, genotoxicity, ecotoxicity, and product quality tests, to evaluate potential health and environmental risks. IIRT aims to advance scientific research and public health through reliable and cost-effective testing services.

1. WELCOME TO IIRT
A Research & Innovation Group

2. INSTITUTE FOR INDUSTRIAL RESEARCH & TOXICOLOGY

3. ABOUT US
Institute for Industrial Research & Toxicology (IIRT) started in the year
2007.
An independent self sustaining, multi-disciplinary contract research
organization (CRO)
Providing exceptionally reliable and cost-effective Laboratory Testing
Services..
IIRT provides Chemical, Microbiological, Pharmacological, Toxicological &
Ecotoxicological testing of Agrochemicals, Microbial Products,
Pharmaceuticals and Medical devices, respectively.

4. BOARD OF DIRECTORS
NN MISHRA ABHISKEK MISHRA SHALINI MISHRA

5. 5
 This multidisciplinary research institute runs with the motto
of “Advancing Life through Novelty and Reliability” and to
provide services to Industry which addresses problems
critical to human health and environment.
 IIRT is committed to develop, innovate, analyze and apply
technology for products and processes.
OUR PROMISE

6. OURSERVICES
• REGULATORY TOXICOLOGY STUDIES
• ECOTOXICOLOGY STUDIES
• DRUG & PHARMA TESTS
• METHOD VALIDATION & CHEMICAL ANALYSIS
• MICROBIOLOGY TESTS

7. SMALL ANIMAL HOUSE FACILITY

8. SMALL ANIMAL HOUSE FACILITY
IIRT specialized animal house facility with controlled environment designed for the
housing, care, and study of laboratory animals like Rat, Mice, Rabbit, Hamster & Guinea
pig. These facilities play a critical role in scientific research across various disciplines,
including biology, medicine, pharmacology, toxicology, and genetics.
Strict hygiene and biosecurity measures are implemented to prevent the introduction and
spread of diseases among animals. Animals are often housed in isolation or specific
pathogen-free (SPF) conditions to ensure their health.
Ethical considerations and animal welfare regulations are followed to ensure the humane
treatment of animals. This includes providing proper housing, nutrition, veterinary care,
and enrichment to promote their well-being.

9. SMALL ANIMAL HOUSE FACILITY

10. INTRAVENOUS TOXICITY TEST

11. INTRAVENOUS TOXICITY TEST
Test Guideline: IP/BP/USP
Intravenous (IV) toxicity testing is a laboratory procedure
used to assess the toxic effects of a substance when it is
administered directly into the bloodstream through
intravenous injection. This type of testing is typically
conducted in animal models, such as rats or rabbits, to
evaluate the potential harm of chemicals,
pharmaceuticals, or other test materials when introduced
directly into the circulatory system.
The primary purpose of intravenous toxicity testing is to
evaluate the acute toxicity of a substance following direct
injection into the bloodstream. It helps assess the
substance's potential to cause systemic toxicity, organ
damage, and lethality.

12. PYROGENICITY/SYSTEMIC TOXICITY TEST IN RABBIT
Test Guideline: IP/BP/USP
Pyrogen toxicity refers to the potential harmful effects of
pyrogens when introduced into the body. Pyrogens are
substances, typically endotoxins or exotoxins, that can
induce fever or an immune response in organisms,
including humans. The term "pyrogen" is derived from the
Greek words "pyro," meaning fire, and "gen," meaning to
produce, reflecting the fever-inducing properties of these
substances.
•Pyrogen testing is crucial in industries that manufacture
or use medical devices, pharmaceuticals, and parenteral
drugs (those administered via injection or infusion). These
products must be free of pyrogens to prevent adverse
reactions in patients.

13. INTRAPERITONEAL TOXICITY TEST IN RAT/MICE
Test Guideline: OECD 420
The intraperitoneal (IP) toxicity test is a laboratory
procedure used to assess the toxic effects of a
substance when it is administered directly into the
peritoneal cavity of test animals, typically rodents like
rats or mice. This test provides information about the
substance's potential to cause toxicity, including
systemic effects, organ damage, and lethality.
The primary purpose of the intraperitoneal toxicity test
is to evaluate the acute toxicity of a substance following
direct injection into the peritoneal cavity. It is commonly
used in toxicological studies to assess the potential
harm posed by chemicals, pharmaceuticals, or other
test materials.

14. ACUTE ORAL TOXICITY TEST IN RAT/MICE
Test Guideline: OECD 420, 423 & 425
Acute oral toxicity testing in rats is a standard
toxicological assessment conducted to evaluate the
potential adverse effects of a substance when it is
ingested orally by rats. This type of testing provides
important data for assessing the safety of chemicals,
pharmaceuticals, and other substances.
The primary objective of acute oral toxicity testing in
rats is to determine the median lethal dose (LD50) or
estimate the dose at which a substance is toxic
enough to cause mortality in 50% of the test animals
within a defined observation period.

15. BACTERIAL ENDOTOXIN TEST (BET)
The bacterial endotoxin test, also known as
the Limulus amebocyte lysate (LAL) test, is a
laboratory assay used to detect and quantify
the presence of bacterial endotoxins in
various substances, particularly
pharmaceuticals, medical devices, and
biological products. Bacterial endotoxins are
lipopolysaccharides (LPS) found in the cell
walls of Gram-negative bacteria. Detecting
and quantifying these endotoxins is essential
for ensuring the safety and quality of medical
and pharmaceutical products.

16. MICROBIAL LIMIT TEST (MLT)
The microbial limit test, also known as microbial
enumeration or microbial bioburden testing, is a
quality control test performed in various industries,
including pharmaceuticals, cosmetics, food, and
beverages. Its purpose is to determine the total
number of viable microorganisms present in a given
sample or product.
The primary goal of the microbial limit test is to assess
the microbial contamination of a product and
determine if it meets specified microbiological quality
standards. This is crucial for product safety, stability,
and shelf life.

17. STERILITY TEST (ST)
The sterility test is a crucial quality control procedure
used primarily in pharmaceutical, biotechnology, and
medical device manufacturing industries to ensure
that products are free from viable microorganisms
that could potentially harm patients or users. The test
aims to confirm that a product, such as a drug,
medical device, or sterile packaging, is sterile and
does not contain any living microorganisms.
The primary goal of the sterility test is to determine
whether a product is free from viable microorganisms
that could cause infections, illnesses, or other
adverse effects when administered to patients or
used in clinical settings.

18. ANALYTICAL TEST LABORATORY
Analytical testing refers to a set of laboratory techniques
and procedures used to determine the chemical
composition, physical properties, quality, and purity of
substances and materials. It plays a critical role in various
industries, including pharmaceuticals, food and
beverages, environmental monitoring, materials science,
and more. Analytical testing is essential for ensuring
product safety, compliance with regulatory standards,
and quality control.
Many industries, such as pharmaceuticals and food
production, are subject to regulatory requirements that
mandate specific analytical testing to ensure product
safety and quality. Compliance with these regulations is
crucial for market approval.

19. DRUG & PHARMA LABORATORY
Pharmaceutical laboratories perform a wide range
of quality control tests to verify the identity,
purity, potency, and safety of pharmaceutical
products. These tests include chemical, physical,
and microbiological analyses.
These laboratories utilize various analytical
techniques and instruments, including high-
performance liquid chromatography (HPLC), gas
chromatography (GC), mass spectrometry (MS),
nuclear magnetic resonance (NMR) spectroscopy,
ultraviolet-visible (UV-Vis) spectroscopy, and
more, to perform tests on drug substances and
pharmaceutical formulations.

20. DRUG & PHARMA LABORATORY
Raw materials used in pharmaceutical production,
such as active pharmaceutical ingredients (APIs),
excipients, and packaging materials, undergo
extensive testing to ensure their quality and suitability
for use.
Pharmaceutical laboratories perform a wide range of
quality control tests to verify the identity, purity,
potency, and safety of pharmaceutical products.
These tests include chemical, physical, and
microbiological analyses. Laboratories develop and
validate analytical methods specific to each drug or
pharmaceutical product. Method validation ensures
that the testing procedures are accurate, precise, and
reliable.

21. METHOD VALIDATION & 5-BATCH ANALYSIS
Method validation is a critical process in analytical
chemistry and laboratory testing. It involves a series
of experiments and procedures to demonstrate
that an analytical method is suitable for its intended
purpose, providing reliable and accurate results.
Method validation is essential to ensure the quality,
accuracy, and consistency of analytical data
generated by a specific method.
Batch analysis in chemistry refers to the process of
analyzing multiple samples or batches of
substances or products for quality control,
research, or testing purposes.

22. GCMS ANALYSIS OF CHEMICAL PRODUCTS
GC-MS, which stands for Gas
Chromatography-Mass Spectrometry, is
a powerful analytical technique used for
the qualitative and quantitative analysis
of a wide range of compounds in various
samples. It combines two separate
analytical methods, gas chromatography
(GC) and mass spectrometry (MS), to
provide detailed information about the
chemical composition of a sample.

23. ACUTE & CHRONIC TOXICITY TEST IN EARTHWORM
Test Guideline: OECD 207 & 222
Earthworm acute toxicity tests are scientific studies designed to assess the
toxic effects of substances or environmental conditions on earthworms
(often Eisenia fetida) over a short exposure period. Earthworms play a vital
role in soil ecosystems and are sensitive indicators of soil quality. These tests
are conducted to evaluate the potential risks of various contaminants,
pesticides, and chemicals to soil ecosystems.
Earthworm reproduction toxicity tests are laboratory experiments designed
to assess the impact of substances or environmental conditions on the
reproductive capabilities of earthworms.
Data from earthworm acute and reproduction toxicity tests may be used in
regulatory evaluations, especially for assessing the safety of pesticides,
chemicals, or soil amendments that could affect soil ecosystems. Regulatory
decisions may be based on these test results.
Eisenia fetida

24. ACUTE CONTACT/ORAL TOXICITY TEST IN HONEYBEE
Test Guideline: OECD 213 & 214
Honey bee oral and contact tests are laboratory-based
experiments designed to evaluate the toxicity of substances
(e.g., pesticides, chemicals) to honey bees (Apis mellifera).
These tests help assess the potential risks of these substances
to honey bee populations and can be crucial for regulatory
approval and environmental protection.
In the contact toxicity test, honey bees are exposed to the test
substance through direct contact with treated surfaces or
materials.
In the oral toxicity test, honey bees are exposed to the test
substance through their food source, often a sugar syrup or
pollen supplement.

25. ACUTE TOXICITY TEST IN FRESHWATER ALGAE
Test Guideline: OECD 201
Algae tests are scientific studies designed to assess the
effects of various factors, including pollutants,
environmental conditions, and treatments, on algal
populations. Algae are essential components of aquatic
ecosystems, and studying their responses can provide
insights into water quality, ecological health, and potential
environmental stressors. Data from algae tests are often
used in regulatory contexts, such as assessing water
quality standards or the environmental impact of industrial
discharges. Regulatory agencies may rely on these tests to
establish guidelines and regulations for pollutant levels in
water bodies
Algae Culture

26. ACUTE TOXICITY TEST IN FISH
Test Guideline: OECD 203
Acute toxicity tests on fish are conducted to assess
the short-term toxic effects of chemicals, pollutants,
or environmental stressors on fish species. These tests
are crucial for evaluating the potential risks that
substances pose to aquatic ecosystems and fisheries.
The data is used to establish the concentration-
response relationship and to calculate key
parameters, such as the median lethal concentration
(LC50) or median effective concentration (EC50) for
the test substance.
Zebra fish

27. ACUTE TOXICITY TEST IN Daphnia magna
Test Guideline: OECD 202
This test is a commonly used bioassay in
ecotoxicology to assess the toxicity of
substances to aquatic organisms, particularly
Daphnia magna, a small freshwater crustacean
commonly known as the water flea. This test is
used to determine the potential harmful
effects of chemicals and pollutants on aquatic
ecosystems.
Daphnia magna

28. Daphnia magna REPRODUCTIVE TOXICITY TEST
Test Guideline: OECD 211
Daphnia magna is commonly used in toxicity
testing to evaluate the effects of chemicals
and pollutants on aquatic life. Their short
reproductive cycle allows for rapid
assessment of potential hazards. Research
involving Daphnia can help identify harmful
substances and assess the ecological risks
associated with various pollutants.

29. AVIAN TOXICITY TEST
Test Guideline: OECD 223
Avian toxicity tests are a type of scientific study designed
to assess the toxic effects of substances or chemicals on
birds. These tests are essential for understanding the
potential risks of environmental contaminants, pesticides,
industrial chemicals, and other substances to avian species
and their ecosystems. Birds can be exposed to the
substance through various methods, such as ingestion
(oral exposure), inhalation (airborne exposure), or dermal
contact (skin exposure). The exposure duration may vary
from acute (short-term) to chronic (long-term) exposure.

30. OUR ACCREDIATION & CERTIFICATION

31. OUR CLIENTS

32. OUR CLIENTS

33. CONTACT US AT