This document discusses outcomes research, which examines the results of implementing healthcare practices based on scientific evidence and patient preferences/values. Outcomes can be related to individuals, groups, organizations, patients, or performance. Outcomes research is important for evaluating scientific evidence effectiveness and informing patients. The Agency for Healthcare Research and Quality and Patient Centered Outcomes Research Institute conduct outcomes research. Benefits include improving practice and informing patients, while excessive funding/time on low-impact research is wasteful. Outcomes research helps ensure best practices and patient-informed decision making.