This document summarizes trends in water, sanitation, and hygiene (WASH)-related mortality in sub-Saharan Africa from 1950 to 2050. It finds that childhood mortality rates have declined across many world regions, including in sub-Saharan Africa. However, WASH-related mortality rates and deaths still remain high in many sub-Saharan African countries and are projected to decline only moderately by 2050 without accelerated interventions and policy changes to improve access to water and sanitation. The document models and compares projections of WASH-related mortality rates and deaths across country groupings in sub-Saharan Africa.