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1. Alex school of Medicine ( ASM team )
Chapter 8 ;
Vitamins

2. Alex school of Medicine ( ASM team )
Fat soluble vitamins

3. Alex school of Medicine ( ASM team )
1. Fat soluble vitamins include all of these except
A) A
B) D
C) E
D ) C
2. Fat soluble vitamins are
A) polar, hydrophobic
B) polar , hydrophilic
C) non polar, hydrophobic
D) non polar, hydrophilic
3. After lipid soluble vitamins absorption they are
transported to
A) Liver
B)Kidney
C)Stomach
4. Lipid soluble vitamins are stored in the liver in the
form of
A) A
B) D
C) K
D) All of the above
5. Lipid soluble vitamins are stored in adipose tissue
in the form of
A) E
B) A
C) C
D) none of the above
6. All of fat soluble vitamins are isoprene
derivatives
A. T
B. F
7. Lipid soluble vitamins are transported by lipo
proteins or specific binding proteins in the
blood
A) T
B) F
8. They are excreted in Urine
A ) T
B) F
9. Toxicity occurs by overdosage because of the
body’s ability to store Excess fat soluble
vitamins Especially E&C
A) T
B) F
Vitamin A
10. The active forms of vit A
A) Retinol
B) Retinal
C) Retionic acid

4. Alex school of Medicine ( ASM team )
D) All of the above
11. Retinol is a complex of 21 carbon arragned
as 7 membered carbocyclic and an 21 carbon
side chain
12. Vit A is derived form
A )isoprene cartones
B) hexose cartones
C) provitamin cartones
13. Retinal is synthesized from
alpha,beta,gama carotnes by Enzyme
A)dehydrase
B)dioxygenase
C)hydratase
14. Retinal is synthesized in
A) Liver
B) intestinal mucosa
C)all of the above
15. Vit A has an animal origin only
A) T
B) F
16. Vit A is absorbed in the lower parts of small
intestine
A) T
B) F
17. B Carotne is converted to vit A in the
liver by carotenase Enzyme
A) T
B) F
18. Vit A is stored in
A) liver
B) small intestine
C) stomach
19. Vit A has a role as an oxidant to reduce
the risk of cancers
A) T
B) F
20. Vit A stimulate the synthesis of specific
proteins by the ribsomes
A) T
B) F
21. Vit A isn’t used for health and the integrity
of the epithelial cells
A) T
B) F
22. Retinol also stimulate the synthesis and
deposition of keratin by epithelial cells
A) T
B) F
23. The Retinal rod cells are adapted for vision
in high night intensities
A) T
B) F
24. The synthetic process of Rhibopsin
proceeds during light
A) T
B) F
25. When rhodopsin is exposed to light , the
bound n_cis Retinal is transformed to all
trans Retinal ( non_enzymatic)

5. Alex school of Medicine ( ASM team )
A) T
B) F
26. The nerve impulse ‘ll transmit through the
optic nerve to the centre of hearing.
A) T
B) F
27. The isomerization of all trans retinal back
to 11 cis_retinal occurs in
A) Liver
B) Intestine
C)Stomach
28. Deficiency of vit A is characterized by
A) Night blindness
B) follicular hype keratosis
C)xerophthalmia
D) all of the above
29. Impaired vision in dim light is the last sign
of vit A deficiency
A) T
B) F
30. follicular hyperkeratosis means
rough,scaly and dry skin with
keratinization of hair
A) T
B) F
31. xerophthalmia means dry eye due to non
kertanization of the eptheliun of lacrimal
glands.
A) T
B) F
32. keratomalacia means
A) keratinization of of the eptheliun of
lacrimal glands
B)keratinization of the cornea
C)k eratinization of the retina
33. Our body requires from vit A
A) 1 mg/day
C) .1 mg/day

6. Alex school of Medicine ( ASM team )
Answers :
1) D
2) C
3) A
4) D
5) E
6) A
7) A
8) B
9) B
10) D
11) B
12) C
13) B
14) C
15) B
16) B
17) A
18) A
19) B
20) A
21) B
22) B
23) B
24) B
25) A
26) B
27) A
28) D
29) B
30) A
31) B
32) B
33) A

7. Alex school of Medicine ( ASM team )
water soluble
vitamins

8. Alex school of Medicine ( ASM team )
I. True or false:
1)all the water soluble vitamins are polar
a) True
b)False
2) The deficiency of water soluble vitamins is
rare
a) True
b)False
3)Cobalamin and Biotin are considered
haematopoietic vitamins
a) True
b)False
4)Dailyerquirements of Thiamine are 5 gm
a) True
b)False
5)Vitamin B1 is a pyrimidine containing
compound
a) True
b)False
6)conversion of Thiamin to its active form
occurs only in brain
a) True
b)False
7)Moderate deficiency of Thiamin by chronic
alcoholism is called “Wernike syndrome”
a) True
b)False
8)Wet beriberi is characterized by peripheral
neuropathy and muscles weakness
a) True
b)False
9)Flavinmononucleotideis formed by ADP-
dependent compound
a) True
b)False
MCQs
1-All of the following is one of the criteria of
an water soluble vitamins except;
a) polar
b)hydrophobic
c)members of B-complex
d)toxicities of them are rare
2)Which of the following is not a human
nutritionally essential B-Vitamin
a)Thiamin
b)Biotin
c)cobalamin
D)Vitamin D
3)Daily requirement of VitaminB1 is
…………. Mg/day

9. Alex school of Medicine ( ASM team )
a)1_3
b)1_2
c)2_4
d)1_4
4)TPP serves as a coenzyme in which of the
following reaction
a)oxidative decarboxylation of Alpha keto
acids
b)Tranketolase reaction
c)acetylcholine synthesis
d)all of above
5)Which of the following cause deficiency of
Thiamin
a)AntiThiamin factors
b)Alcoholism
c)malabsorptionor low intake
d)all of the above
6)Dry beriberi is characterized by all of the
following except
a)muscles atrophy
b)peripheral neuropathy
c)Oedema
D)non of the above
7)Animal sources of Thiamin are
a)liver
b)kidney
c)milk
d)all of the above

10. Alex school of Medicine ( ASM team )
ANSWERS:
True,false
1-a
2-b
3-b
4-b
5-a
6-b
7-a
8-a
9-b
MCQs
1-b
2-d
3-b
4-d
5-d
6-c
7-d

11. Alex school of Medicine ( ASM team )
1) Vitamin B6 consists of 3 pyridine
derivatives except
a) pyridoxine
b) pyridoxamine
c) biotin
d) pyridoxal
2) All forms of vitamin B6 are absorbed in the
a) stomach
b) intestine
c) liver
d) None of the above
3) The enzyme ………………. Catalyzes the
phosphorylation by ATB of all forms of
vitamin B6
a) Dehydrogenase
b) Mutase
c) pyridoxal kinase
d) All of the above
4) Which forms of vitamin B6 are active as
coenzyme
a) pyridoxal phosphate
b) pyridoxamine phosphate
c) pyridoxine phosphate
d)Both (a) and( b)
5) pyridoxine coenzymes are important
in……………… reactions of amino acids as
they are important for synthesis of
neurotransmitters
a) decarboxylation
b) threoninealdolase reaction
c) non oxidative deamination
d) all of the above

12. Alex school of Medicine ( ASM team )
6) pyridoxal phosphate is essential for energy
production as it is essential component of
…………. Enzyme
a) glycogenphosphorylase
b) kinase
c) decarboxylase
d) mutase
7) Vitamin B6 is essential for the synthesis of
some neurotransmitters , it’sdeficiencycauses
………..
a) anemia
b) Convulsions and peripheral neuropathy
c) Peripheral neuritis
d) All of the above
8) Biotin is a sulphurcontaining vitamin
consisting of fused two imidazole rings
a) True
b) False
9) Biotin is formed by an enzyme
called………………..
Which binds biotin to a ………..
a) Dehydrogenase lysine
b) Holocarboxylase CO2
c) Holocarboxylase lysine
d)kinase PO4
10)Acetyl CoA ………… converts acetyl CoA
to malonylCoA ,an important step in the
extramitochondrial biosynthetic pathway
for………..
a) Dehydrogenaseamino acid
b) Decarboxylase fatty acid
c) Thiokinaseamino acid
d) Carboxylasefatty acids
11) Deficiency can be induced in animals by
giving them parenteral antibacterial drugs.
a) True
b) False
12)Avidin cause biotin deficiency by forming
digestible form preventingit’sabsorbtion
a) True

13. Alex school of Medicine ( ASM team )
b) False
13) The oxidized form of Lipoic acid has a
linear disulfide while the redused form with
open chain.
a) True
b)False
14)Lipoic acid is important as coenzyme in the
…………..
Of pyruvate and other ketoacids.
a) Oxidative carboxylation
b) phosphorylation
c) Oxidative decarboxylation
d) None of the above
15) Deficiency of Lipoic acid cause
neurological inflammation .
a)True
b) False
Answers:
1)c
2)B
3) C
4)d
5)a
6)a
7)b
8)b
9)c
10)d
11)b
12)b
13)b
14)c
15)a

14. Alex school of Medicine ( ASM team )
1- Water soluble vitamins are
a) Hydrophilic molecules .
b) Members of B-complex and
vitamin c .
c) Non polar .
d) A & b
2- Human nutritionally essential B-
vitamins involve :
a) Tocopherols .
b) Biotin .
c) Vitamin A .
d) Non of the above
3- Conversion of thiamin to thiamin
diphosphate occurs in :
a) Kidney .
b) Liver .
c) Muscles .
d) Spleen .
4- Antithiamine factors cause cleavage of
thiamin producing :
a) Niacin .
b) Burine .
c) Pyrimidine .
d) All of the above .
5- All of the following are functions of
Flavoprotein enzymes except :
a) Oxidative decarboylation of
alpha-ketoacids .
b) Dehydrogenation of succinic acid .
c) Oxidative degradation of fatty
acids .
d) Synthesis of amino levulinicacid .
6- Nicotinic acid is a bicarboxylic acid
derivative of pyridine :
a) True .
b) False .
7- Dermatitis , Diarrhea and Dementia
are symptoms of :
a) Pellagra .
b) HartnupDisease .
c) WernikeKorsacoffSyndrome .
d) Beriberi .
8- Folatereductase is one of :
a) Dehydrogenase enzymes that
utilize NAD+ .

15. Alex school of Medicine ( ASM team )
b) Dehydrogenase that utilize
pyridine coenzymes .
c) Dehydrogenase linked to NADP+ .
d) All of the above .
9- Coenzyme A consists :
a) Riboflavin .
b) Active thiamin .
c) Active pantothenic .
d) Vitamin B6 .
10-Vitamin B6 consists of :
a) Pyridoxine .
b) Pyridoxal .
c) Pyridoxamine .
d) All of the above .
11-Vitamin B6 is absorbed from :
a) Liver .
b) Intestine .
c) Portal vien .
d) Stomach .
12-Synthesis of some neurotransmitters
requires :
a) Biotin .
b) Lipoicacid .
c) Pyridoxine .
d) Niacin .
13-Non oxidative deamination of serine is
catalyzed by :
a) Dehydratase .
b) Dehydrogenase .
c) Mutase .
d) Lyase .
14-The deficiency of vitamin B6 causes
anemia :
a) True .
b) False .
15-The formation of biocytin is done by :
a) Pyruvate carboxylase .
b) Acetyl COA carboxylase .
c) Holocarboxylasesynthase .
d) None of the above .
16-Acetyl COA carboxylase converts
pyruvate to oxaloacetate :
a) True .
b) False .
17-Avidin prevent the absorption of :
a) Niasin .
b) Vitamin B6 .
c) Vitamin C .
d) None of the above .
18-Lipoic acid is all of the following
except :
a) Polar .
b) Non sulphur containing vitamin .
c) Water soluble vitamin .
d) 6,8dithiooctanic acid .

16. Alex school of Medicine ( ASM team )
19-Peripheral Neuritis is caused by :
a) Vitamin B6 deficiency .
b) Vitamin C deficiency .
c) Lipoic acid deficiency .
d) Biotic acid deficiency .
20-Dyhydroascorbate is found in :
a) Body fluids .
b) Intestine .
c) Liver .
d) All of the above .
21-Vitamin C can be synthesized from :
a) Galactose .
b) Fructose .
c) Maltose .
d) Glucose .
22-D ascorbic acid is the biologically
active form of Vitamin C :
a) True .
b) False .
23-Absorption of iron by reducing it to
ferrous occurs In :
a) Intestine .
b) Body fluids .
c) Liver .
d) Stomach .
24-Scurvy is characterized by all of the
following except :
a) Gingivitis .
b) Anemia .
c) Photophobia .
d) Defect in bone formation .
Answers :
1. D
2. B
3. B
4. C
5. D
6. B
7. A
8. C
9. C
10. D
11. B
12. C