Psycho-sexual Disorders(Common Factors & Symptoms)CMC M
Psycho-sexual dysfunction may be defined as inability to become sexually aroused or achieve sexual satisfaction in the appropriate situations because of mental or emotional reasons.
Psycho-sexual Disorders(Common Factors & Symptoms)CMC M
Psycho-sexual dysfunction may be defined as inability to become sexually aroused or achieve sexual satisfaction in the appropriate situations because of mental or emotional reasons.
female sexual dysfunction
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female sexual dysfunction
For More Medicine Free PPT - http://playnever.blogspot.com/
For Health benefits and medicine videos Subscribe youtube channel - https://www.youtube.com/playlist?list=PLKg-H-sMh9G01zEg4YpndngXODW2bq92w
Erectile Dysfunction is larger health problems for men. It can be solved with some natural pills or other solutions. These pills are helps to recover from Erectile Dysfunction.
Dr. Aaron Spitz's presentation as Associate Professor at UCI Urology. This presentation covers how couples can work together to improve their sexual health.
Premature ejaculation (PE) is a common sexual health condition that affects many men. Herbal treatments offer a natural approach to managing this condition and improving overall sexual health.
In this mini book, we will explore various herbal remedies that have been used to treat PE. We will discuss the different herbs and their properties, including their effects on sexual function, recommended dosages, and potential side effects.
You will learn about the importance of proper preparation and dosage when using herbs for medicinal purposes, as well as how to safely incorporate herbal remedies into your daily routine. We will also discuss lifestyle changes that can help to manage PE, such as exercise, diet, and stress reduction techniques.
With the help of herbal treatments, men can improve their sexual function and enhance their overall quality of life. By taking a holistic approach to sexual health and incorporating herbal remedies into their routine, men can experience the many benefits of natural medicine and achieve optimal wellbeing.
remature ejaculation (PE) is a common sexual health condition that affects many men. Herbal treatments offer a natural approach to managing this condition and improving overall sexual health.
In this mini book, we will explore various herbal remedies that have been used to treat PE. We will discuss the different herbs and their properties, including their effects on sexual function, recommended dosages, and potential side effects.
You will learn about the importance of proper preparation and dosage when using herbs for medicinal purposes, as well as how to safely incorporate herbal remedies into your daily routine. We will also discuss lifestyle changes that can help to manage PE, such as exercise, diet, and stress reduction techniques.
With the help of herbal treatments, men can improve their sexual function and enhance their overall quality of life. By taking a holistic approach to sexual health and incorporating herbal remedies into their routine, men can experience the many benefits of natural medicine and achieve optimal wellbeing.
Premature ejaculation (PE) is a common sexual health condition that affects many men. Herbal treatments offer a natural approach to managing this condition and improving overall sexual health.
In this mini book, we will explore various herbal remedies that have been used to treat PE. We will discuss the different herbs and their properties, including their effects on sexual function, recommended dosages, and potential side effects.
You will learn about the importance of proper preparation and dosage when using herbs for medicinal purposes, as well as how to safely incorporate herbal remedies into your daily routine. We will also discuss lifestyle changes that can help to manage PE, such as exercise, diet, and stress reduction techniques.
With the help of herbal treatments, men can improve their sexual function and enhance their overall quality of life.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
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1. Dr Hosam Hassan
Egyptian Fellowship of Psychiatry
Senior Registrar Psychiatrist
Mental Health Hospital In Taif
2.
3. Why are we discussing Sexual Disorders ?
When to consider diagnosing a Sexual Disorder
?
How can we manage Sexual Disorders ?
4. Sexual
Disorder
Non Adherence
Low Self Esteem
DepressionAnxiety
Dissatisfaction
Low Quality of
Life
Relapse
Interpersonal
Troubles
Substance Abuse
Mental
Illness
Medications
5. 31 %
43 %
Sexual Dysfunction
in
18-59 years old males
Sexual Dysfunction
in
18-59 years old females
Up to 60%
Sexual Dysfunction
in
Patients taking
Antipsychotics
Up to 80%
Sexual Dysfunction
in
Patients taking
Antidepressants
20. Cautious
Contraindicated
BP
Precautions Before Prescribing PDE-5
Heart Diseases
Nitrates
α- Adrenergic
Blockers
Isosorbide dinitrate
Isosorbide mononitrate
Nitroglycerin
Trazodone
Mirtazapine
Yohimbine
Prazosin
MI
Sudden Death
Post Coital
21. Duration of ActionOnset of Action
Dosage
& Administration
Drug
About 4 Hours
(8-12hrs if Mild ED)
1 hr50 mg (up to 100 mg / dose)
(25mg if side effects are present)
On empty stomach
Sildenafil
(Viagra)
About 4 Hours
(8-12hrs if Mild ED)
1 hr
ODT form 30 min
10 – 20 mg
On empty Stomach
Vardanafil
(Levitra)
Up to 36 hrs1 hr10 – 20 mg
2.5 – 5 mg / day (on daily basis ) if
complete ED
Tadalafil
(Cialis)
About 4 Hours
(8-12hrs if Mild ED)
30 min onset
15 min onset
50 – 100 mg
100 – 200 mg
Avanafil
(Spedra)
Side Effects BlueVision 3%
Flushing 12%
Headache 11%
Dyspepsia 5%
Hearing Loss
Optic Neuropathy
22. Management of Female Sexual Dysfunction
•Gynecologist
•Psychiatrist
•Cardiologist
•Sex / CoupleTherapist
•Pelvic PhysicalTherapist
• Non-Pharmacological
• Hormonal
• Other Pharmacological
•Desire / Arousal
•Pelvic Pain
•Orgasm
• Social / Partner
• Psychological
• Physical
Multi
Factorial
Multi
Faceted
Team
Approach
Treatment
plan
24. PharmacologicalTherapies
Flibanserin
(Addyi)
Centrally Acting Serotonin Modulator
1st & currently the only FDA approved
medication for females sexual dysfunction
(Approved on August 2015)
Modest increase in Sexually Satisfying Events & Sexual Desire
Dose &
Administration
100 mg / daily
Bed time
1 month
onset of efficacy
Side Effects
Somnolence
Dizziness
Fatigue
Headache
precautions
Safety in Pregnancy ??
Drug Interaction ??
Syncope ??
25. PDE-5
inhibitors
Effective in SSRIs Related
Sexual Dysfunction
In Premenopausal women
Herbal supplements
Bupropion
150 – 300 mg SR / day
Effective in premenopausal females
With arousal/interest dysfunction
without underlying depression
Buspirone
Effective in SSRIs Related
Sexual Dysfunction
In Premenopausal women
precautions
Safety & Efficacy Unproven
Minimal Regulatory Oversight
Usually Costly
Considerations
Predicted 30% Placebo Response
Few reported side effects
Alvimil
Supplement
Zestra
Massage Oil
Examples
26. HormonalTherapy
Androgen Estrogen Ospemifen Tibolone
OtherTherapies
Clitoral SuctionVacuum Device
Not available now
High Cost yet as effective as over-the-counter devices
Hirsutism ,Acne
(mild, transient )
Not Effective in SDs 1st FDA approved for
Dyspareunia
(Vulvovaginal Atrophy)
Not FDA approved
Risk Outweigh Benefit
27. Sexual dysfunction in the United States: prevalence and
predictors (1999)
Laumann EO, Paik A, Rosen RC
Treatment-emergent sexual dysfunction related to
antidepressants: a meta-analysis (2009)
Serretti A, Chiesa A
Overview of male sexual dysfunction, UpToDate (2015)
Glenn R Cunningham, Rosen RC
. Evaluation of Flibanserin: Science and Advocacy at the
FDA (2015)
GelladWF, Flynn KE, Alexander GC