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TYPHOID
MARY
Dilip Kumar Jena
Mary Mallon
LIFE HYSTORY
Name
 Mary Mallon
Born
 September 23, 1869
Cookstown, County Tyrone, Ireland
Died
 November 11, 1938 (aged 69)
North Brother Island, East River, New York, U.S.
Residence
 United States
Occupation
 Cook
Known for
 Asymptomatic carrier of typhoid fever
Early life
 Mary Mallon was born in 1869 in Cookstown,
County Tyrone, Ireland. She emigrated from
Ireland to the United States in 1883 at the age
of 15. She lived with her aunt and uncle for a
time and later found work as a cook for affluent
families.
Career
 From 1900 to 1907 Mallon worked as a cook
in the New York City area for seven different
families. In 1900, she worked in Mamaroneck,
New York, where, within two weeks of her
employment, residents developed typhoid
fever. In 1901 she moved to Manhattan, where
members of the family for whom she worked
developed fevers and diarrhea, and the
laundress died. Mallon then went to work for a
lawyer; she left after seven of the eight people
in that household became ill.
Career
In 1906, she took a position in Oyster Bay,
Long Island, and within two weeks ten of
eleven family members were hospitalized
with typhoid. She changed jobs again, and
similar occurrences happened in three
more households. She worked as a cook
for the family of a wealthy New York banker,
Charles Henry Warren. When the Warrens
rented a house in Oyster Bay for the
summer of 1906, Mallon went along too.
From August 27 to September 3, six of the
eleven people in the family came down with
typhoid fever. The disease at that time was
"unusual" in Oyster Bay, according to three
medical doctors who practiced there.
Mallon was subsequently hired by other
families, and outbreaks followed her.
Investigation
 In late 1906, one family hired a typhoid researcher
named George Soper to investigate. Soper
published the results on June 15, 1907, in the
Journal of the American Medical Association. He
believed Mallon might be the source of the
outbreak.
 He wrote:-"It was found that the family changed
cooks on August 4. This was about three weeks
before the typhoid epidemic broke out. She
remained in the family only a short time, leaving
about three weeks after the outbreak occurred.
The cook was described as an Irish woman about
40 years of age, tall, heavy, single. She seemed
to be in perfect health."
Investigation
 Soper discovered that a female Irish cook, who
fit the physical description he was given, was
involved in all of the outbreaks. He was unable
to locate her because she generally left after
an outbreak began, without giving a forwarding
address. Soper learned of an active outbreak
in a penthouse on Park Avenue, and
discovered Mallon was the cook. Two of the
household's servants were hospitalized, and
the daughter of the family died of typhoid.
Investigation
 When Soper approached Mallon about her
possible role in spreading typhoid, she adamantly
rejected his request for urine and stool samples.
Since Mallon refused to give samples, he decided
to compile a five-year history of Mallon's
employment. Soper found that of the eight families
that hired Mallon as a cook, members of seven
claimed to have contracted typhoid fever. On his
next visit, he brought another doctor with him but
again was turned away. During a later encounter
when Mallon was herself hospitalized, he told her
he would write a book and give her all the
royalties. She angrily rejected his proposal and
locked herself in the bathroom until he left.
First quarantine (1907–10)
Mary Mallon in a hospital bed
during her first quarantine
The New York City Health
Department finally sent physician
Sara Josephine Baker to talk to
Mallon. Baker stated "by that time
she was convinced that the law
was only persecuting her when she
had done nothing wrong." A few
days later, Baker arrived at Mallon's
workplace with several police
officers, who took her into custody.
Mary attracted so much media
attention that in a 1908 issue of the
Journal of the American Medical
Association she was called
"typhoid Mary". Later, in a textbook
that defined typhoid fever, she was
called "Typhoid Mary“.
First quarantine (1907–10)
 Mallon admitted poor hygiene, saying she did not
understand the purpose of hand-washing because
she did not pose a risk. In prison, she was forced
to give stool and urine samples. Doctors found a
significant nidus of typhoid bacteria in her
gallbladder. Authorities suggested removing her
gallbladder, but she refused as she did not believe
she carried the disease. She was also unwilling to
cease working as a cook.
 The New York City Health Inspector determined
her to be a carrier. Under sections 1169 and 1170
of the Greater New York Charter, Mallon was held
in isolation for three years at a clinic located on
North Brother Island.
First quarantine (1907–10)
 Eventually, Eugene H. Porter, the New York State
Commissioner of Health, decided that disease
carriers should no longer be kept in isolation and
that Mallon could be freed if she agreed to stop
working as a cook and take reasonable steps to
prevent transmitting typhoid to others. On
February 19, 1910, Mallon agreed that she "[was]
prepared to change her occupation (that of a
cook), and would give assurance by affidavit that
she would upon her release take such hygienic
precautions as would protect those with whom
she came in contact, from infection". She was
released from quarantine and returned to the
mainland.
Release and second quarantine (1915–
38)
 Upon her release, Mallon was given a job as a
laundress, which paid less than cooking. She
soon changed her name to "Mary Brown", and
returned to her old occupation. For the next
five years, she worked in a number of
kitchens; wherever she worked, there were
outbreaks of typhoid. However, she changed
jobs frequently, and Soper was unable to find
her.
Release and second quarantine
(1915–38)
 In 1915, Mallon started another major outbreak, this
time at Sloane Hospital for Women in New York City.
Twenty-five people were infected and two died. She
again left, but the police were able to find and arrest
her when she brought food to a friend on Long Island.
After arresting her, public health authorities returned
her to quarantine on North Brother Island on March
27, 1915. She was still unwilling to have her
gallbladder removed. Mallon remained confined for
the remainder of her life. She became a minor
celebrity, and was occasionally interviewed by the
media. They were told not to accept even water from
her. Later, she was allowed to work as a technician in
the island's laboratory, washing bottles.
Death
Mallon spent the rest of her
life in quarantine at the
Riverside Hospital. Six years
before her death, she was
paralyzed by a stroke. On
November 11, 1938, she died
of pneumonia at age 69. An
autopsy found evidence of
live typhoid bacteria in her
gallbladder. Mallon's body
was cremated, and her ashes
were buried at Saint
Raymond's Cemetery in the
Bronx
Learning points
 In August 2013, researchers at the Stanford University
School of Medicine announced they were making
breakthroughs in understanding the exact science
behind asymptomatic carriers such as Mallon. The
bacteria that cause typhoid may hide in macrophages, a
type of immune cell.
 Individuals can develop typhoid fever after ingesting
food or water contaminated during handling by a human
carrier. The human carrier may be a healthy person who
has survived a previous episode of typhoid fever yet
who continues to shed the associated bacteria,
Salmonella typhi, in feces and urine. Washing hands
with soap before touching or preparing food, washing
dishes and utensils with soap and water, and only eating
cooked food are all ways to reduce the risk of typhoid
infection.
THANK YOU
 IS THIS RIGHT TIME TO THINK
ABOUT FOOD SAFETY ?
 THE ANSWER IS YES.

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Typhid mary

  • 3. LIFE HYSTORY Name  Mary Mallon Born  September 23, 1869 Cookstown, County Tyrone, Ireland Died  November 11, 1938 (aged 69) North Brother Island, East River, New York, U.S. Residence  United States Occupation  Cook Known for  Asymptomatic carrier of typhoid fever
  • 4. Early life  Mary Mallon was born in 1869 in Cookstown, County Tyrone, Ireland. She emigrated from Ireland to the United States in 1883 at the age of 15. She lived with her aunt and uncle for a time and later found work as a cook for affluent families.
  • 5. Career  From 1900 to 1907 Mallon worked as a cook in the New York City area for seven different families. In 1900, she worked in Mamaroneck, New York, where, within two weeks of her employment, residents developed typhoid fever. In 1901 she moved to Manhattan, where members of the family for whom she worked developed fevers and diarrhea, and the laundress died. Mallon then went to work for a lawyer; she left after seven of the eight people in that household became ill.
  • 6. Career In 1906, she took a position in Oyster Bay, Long Island, and within two weeks ten of eleven family members were hospitalized with typhoid. She changed jobs again, and similar occurrences happened in three more households. She worked as a cook for the family of a wealthy New York banker, Charles Henry Warren. When the Warrens rented a house in Oyster Bay for the summer of 1906, Mallon went along too. From August 27 to September 3, six of the eleven people in the family came down with typhoid fever. The disease at that time was "unusual" in Oyster Bay, according to three medical doctors who practiced there. Mallon was subsequently hired by other families, and outbreaks followed her.
  • 7. Investigation  In late 1906, one family hired a typhoid researcher named George Soper to investigate. Soper published the results on June 15, 1907, in the Journal of the American Medical Association. He believed Mallon might be the source of the outbreak.  He wrote:-"It was found that the family changed cooks on August 4. This was about three weeks before the typhoid epidemic broke out. She remained in the family only a short time, leaving about three weeks after the outbreak occurred. The cook was described as an Irish woman about 40 years of age, tall, heavy, single. She seemed to be in perfect health."
  • 8. Investigation  Soper discovered that a female Irish cook, who fit the physical description he was given, was involved in all of the outbreaks. He was unable to locate her because she generally left after an outbreak began, without giving a forwarding address. Soper learned of an active outbreak in a penthouse on Park Avenue, and discovered Mallon was the cook. Two of the household's servants were hospitalized, and the daughter of the family died of typhoid.
  • 9. Investigation  When Soper approached Mallon about her possible role in spreading typhoid, she adamantly rejected his request for urine and stool samples. Since Mallon refused to give samples, he decided to compile a five-year history of Mallon's employment. Soper found that of the eight families that hired Mallon as a cook, members of seven claimed to have contracted typhoid fever. On his next visit, he brought another doctor with him but again was turned away. During a later encounter when Mallon was herself hospitalized, he told her he would write a book and give her all the royalties. She angrily rejected his proposal and locked herself in the bathroom until he left.
  • 10. First quarantine (1907–10) Mary Mallon in a hospital bed during her first quarantine The New York City Health Department finally sent physician Sara Josephine Baker to talk to Mallon. Baker stated "by that time she was convinced that the law was only persecuting her when she had done nothing wrong." A few days later, Baker arrived at Mallon's workplace with several police officers, who took her into custody. Mary attracted so much media attention that in a 1908 issue of the Journal of the American Medical Association she was called "typhoid Mary". Later, in a textbook that defined typhoid fever, she was called "Typhoid Mary“.
  • 11. First quarantine (1907–10)  Mallon admitted poor hygiene, saying she did not understand the purpose of hand-washing because she did not pose a risk. In prison, she was forced to give stool and urine samples. Doctors found a significant nidus of typhoid bacteria in her gallbladder. Authorities suggested removing her gallbladder, but she refused as she did not believe she carried the disease. She was also unwilling to cease working as a cook.  The New York City Health Inspector determined her to be a carrier. Under sections 1169 and 1170 of the Greater New York Charter, Mallon was held in isolation for three years at a clinic located on North Brother Island.
  • 12. First quarantine (1907–10)  Eventually, Eugene H. Porter, the New York State Commissioner of Health, decided that disease carriers should no longer be kept in isolation and that Mallon could be freed if she agreed to stop working as a cook and take reasonable steps to prevent transmitting typhoid to others. On February 19, 1910, Mallon agreed that she "[was] prepared to change her occupation (that of a cook), and would give assurance by affidavit that she would upon her release take such hygienic precautions as would protect those with whom she came in contact, from infection". She was released from quarantine and returned to the mainland.
  • 13. Release and second quarantine (1915– 38)  Upon her release, Mallon was given a job as a laundress, which paid less than cooking. She soon changed her name to "Mary Brown", and returned to her old occupation. For the next five years, she worked in a number of kitchens; wherever she worked, there were outbreaks of typhoid. However, she changed jobs frequently, and Soper was unable to find her.
  • 14. Release and second quarantine (1915–38)  In 1915, Mallon started another major outbreak, this time at Sloane Hospital for Women in New York City. Twenty-five people were infected and two died. She again left, but the police were able to find and arrest her when she brought food to a friend on Long Island. After arresting her, public health authorities returned her to quarantine on North Brother Island on March 27, 1915. She was still unwilling to have her gallbladder removed. Mallon remained confined for the remainder of her life. She became a minor celebrity, and was occasionally interviewed by the media. They were told not to accept even water from her. Later, she was allowed to work as a technician in the island's laboratory, washing bottles.
  • 15. Death Mallon spent the rest of her life in quarantine at the Riverside Hospital. Six years before her death, she was paralyzed by a stroke. On November 11, 1938, she died of pneumonia at age 69. An autopsy found evidence of live typhoid bacteria in her gallbladder. Mallon's body was cremated, and her ashes were buried at Saint Raymond's Cemetery in the Bronx
  • 16. Learning points  In August 2013, researchers at the Stanford University School of Medicine announced they were making breakthroughs in understanding the exact science behind asymptomatic carriers such as Mallon. The bacteria that cause typhoid may hide in macrophages, a type of immune cell.  Individuals can develop typhoid fever after ingesting food or water contaminated during handling by a human carrier. The human carrier may be a healthy person who has survived a previous episode of typhoid fever yet who continues to shed the associated bacteria, Salmonella typhi, in feces and urine. Washing hands with soap before touching or preparing food, washing dishes and utensils with soap and water, and only eating cooked food are all ways to reduce the risk of typhoid infection.
  • 17. THANK YOU  IS THIS RIGHT TIME TO THINK ABOUT FOOD SAFETY ?  THE ANSWER IS YES.