Treatment as Prevention is not a magic bullet on its own. It requires a combination approach that addresses clinical, community, and structural factors. For Treatment as Prevention to work, the "Gardner cascade" needs to change - more testing, linking people to care, keeping them in care, and improving adherence to treatment. Health reform creates opportunities to rethink siloed HIV programs and integrate services through coordinated agencies. This may involve AIDS service organizations transitioning to community health organizations that address social determinants of health with HIV community health workers.