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- Harrison's Principles of Internal Medicine is considered the most reliable textbook in medicine. The 18th edition has been extensively modified and expanded by leading doctors. - It covers more aspects of global medicine than any other textbook, including new sections on systems biology, the human microbiome, biology of aging, and neuropsychiatric disorders in war veterans. - In addition to comprehensive coverage of disease systems and management, it includes a multimedia DVD with over 2,000 images and videos demonstrating clinical procedures, as well as PowerPoint presentations for classroom lectures.
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![-2029206-963168<br />Harrison's Principles of Internal Medicine: Volumes 1 and 2, 18th Edition [Hardcover]<br />Harrison's Principles of Internal Medicine Review<br />Probably the most reliable textbook in medicine -- featuring the acclaimed Harrison's DVD with 57 additional sections and exclusive video and lessons<br />Now presented in 2 VOLUMES<br />Extensively modified and broadened through the world’s leading doctors, Harrison’s Principles of Internal Medicine, 18e is constantly on the elevated the bar because the pinnacle of current medical understanding and exercise, providing the definitive overview of disease systems and management.<br />CURRENT<br />All sections appear to have been up-to-date to mirror the most recent understanding and evidence, and important new sections happen to be added, including: quot;
Systems Biology in Health insurance and Disease,quot;
quot;
A Persons Microbiome,quot;
quot;
The Biology of Aging,quot;
and quot;
Neuropsychiatric Ailments in War Veterans.quot;
<br />CONNECTED<br />Harrison's covers more global facets of medicine than every other textbook, and features such sections as quot;
Global Issues in Medicine,quot;
by Jim Yong Kim, Paul Player, and Frederick Rhatigan, and a new comer to the 18th edition, quot;
Primary Care in Low and Middle Earnings Nations.quot;
<br />COMPREHENSIVE<br />Not one other resource provides coverage of disease systems and management like Harrison's, including world-famous sections on Aids/Helps, STEMI and non-STEMI myorcardial infarction, cancer biology, ms, and diabetes.<br />The Harrison’s Multi-Media DVD- Fantastic!<br />The Harrison’s DVD continues to be broadened to incorporate a comprehensive video illustration showing the nerve physical examination, and video lessons regarding how to perform essential clinical methods, including:<br /> Thoracentesis<br /> Abdominal Paracentesis<br /> Endotracheal Intubation<br /> Central Venous Catheter Positioning<br />57 additional sections and most 2,000 images result in the companion DVD an important a part of every physician's education, practice, and long term learning.The DVD also features Ms powerpoint presentations from fifty sections to facilitate class lectures, along with a free trial offer subscription to AccessMedicine.com (including Harrison's Online).<br />Harrison’s 18e is proud to provide a tribute to longtime editor, Eugene Braunwald, MD for his outstanding and ongoing contributions to medical understanding and exercise.<br />>>GET IT NOW<<<br />](https://image.slidesharecdn.com/titanic-booksdocx4240/85/titanic-books-docx-1-320.jpg)
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Giloy, also known as Guduchi or Amrita in classical Ayurvedic texts, is a revered herb renowned for its myriad health benefits. It is categorized as a Rasayana, meaning it has rejuvenating properties that enhance vitality and longevity. Giloy is celebrated for its ability to boost the immune system, detoxify the body, and promote overall wellness. Its anti-inflammatory, antipyretic, and antioxidant properties make it a staple in managing conditions like fever, diabetes, and stress. The versatility and efficacy of Giloy in supporting health naturally highlight its importance in Ayurveda. At Planet Ayurveda, we provide a comprehensive range of health services and 100% herbal supplements that harness the power of natural ingredients like Giloy. Our products are globally available and affordable, ensuring that everyone can benefit from the ancient wisdom of Ayurveda. If you or your loved ones are dealing with health issues, contact Planet Ayurveda at 01725214040 to book an online video consultation with our professional doctors. Let us help you achieve optimal health and wellness naturally.
Travel Clinic Cardiff: Health Advice for International Travelers
Travel Clinic Cardiff offers comprehensive travel health services, including vaccinations, travel advice, and preventive care for international travelers. Our expert team ensures you are well-prepared and protected for your journey, providing personalized consultations tailored to your destination. Conveniently located in Cardiff, we help you travel with confidence and peace of mind. Visit us: www.nxhealthcare.co.uk
June 2024 Oncology Cartoons By Dr Kanhu Charan Patro
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Patellar Instability: Diagnosis Management
Pictorial and detailed description of patellar instability with sign and symptoms and how to diagnose , what investigations you should go with and how to approach with treatment options . I have presented this slide in my 2nd year junior residency in orthopedics at LLRM medical college Meerut and got good reviews for it
After getting it read you will definitely understand the topic.
Breast cancer: Post menopausal endocrine therapy
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
STUDIES IN SUPPORT OF SPECIAL POPULATIONS: GERIATRICS E7
Unit 4: MRA 103T Regulatory affairs
This guideline is directed principally toward new Molecular Entities that are
likely to have significant use in the elderly, either because the disease intended
to be treated is characteristically a disease of aging ( e.g., Alzheimer's disease) or
because the population to be treated is known to include substantial numbers of
geriatric patients (e.g., hypertension).
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- 1. -2029206-963168<br />Harrison's Principles of Internal Medicine: Volumes 1 and 2, 18th Edition [Hardcover]<br />Harrison's Principles of Internal Medicine Review<br />Probably the most reliable textbook in medicine -- featuring the acclaimed Harrison's DVD with 57 additional sections and exclusive video and lessons<br />Now presented in 2 VOLUMES<br />Extensively modified and broadened through the world’s leading doctors, Harrison’s Principles of Internal Medicine, 18e is constantly on the elevated the bar because the pinnacle of current medical understanding and exercise, providing the definitive overview of disease systems and management.<br />CURRENT<br />All sections appear to have been up-to-date to mirror the most recent understanding and evidence, and important new sections happen to be added, including: quot; Systems Biology in Health insurance and Disease,quot; quot; A Persons Microbiome,quot; quot; The Biology of Aging,quot; and quot; Neuropsychiatric Ailments in War Veterans.quot; <br />CONNECTED<br />Harrison's covers more global facets of medicine than every other textbook, and features such sections as quot; Global Issues in Medicine,quot; by Jim Yong Kim, Paul Player, and Frederick Rhatigan, and a new comer to the 18th edition, quot; Primary Care in Low and Middle Earnings Nations.quot; <br />COMPREHENSIVE<br />Not one other resource provides coverage of disease systems and management like Harrison's, including world-famous sections on Aids/Helps, STEMI and non-STEMI myorcardial infarction, cancer biology, ms, and diabetes.<br />The Harrison’s Multi-Media DVD- Fantastic!<br />The Harrison’s DVD continues to be broadened to incorporate a comprehensive video illustration showing the nerve physical examination, and video lessons regarding how to perform essential clinical methods, including:<br /> Thoracentesis<br /> Abdominal Paracentesis<br /> Endotracheal Intubation<br /> Central Venous Catheter Positioning<br />57 additional sections and most 2,000 images result in the companion DVD an important a part of every physician's education, practice, and long term learning.The DVD also features Ms powerpoint presentations from fifty sections to facilitate class lectures, along with a free trial offer subscription to AccessMedicine.com (including Harrison's Online).<br />Harrison’s 18e is proud to provide a tribute to longtime editor, Eugene Braunwald, MD for his outstanding and ongoing contributions to medical understanding and exercise.<br />>>GET IT NOW<<<br />