The thoracic duct is the largest lymphatic vessel in the body. It begins in the abdomen at the lower border of the T12 vertebrae and extends upwards through the posterior and superior mediastinum to the neck. At the C7 vertebral level, it arches laterally and drains into the junction of the left internal jugular and subclavian veins. It drains lymph from the entire body below the diaphragm and left side of the body above the diaphragm, receiving tributaries from lymph nodes and vessels along its course. Injuries or obstructions to the thin-walled thoracic duct can lead to fluid accumulation in the thorax or abdomen.
The thyroid gland is a butterfly-shaped endocrine gland located in the front of the neck. It weighs around 25 grams and is composed of two lateral lobes connected by a narrow isthmus. The gland is situated anterior to the larynx and trachea. It receives blood supply from the superior, inferior, and sometimes thyroid ima arteries, and drains into the superior, middle, and inferior thyroid veins. Lymphatic drainage occurs into the prelaryngeal, pretracheal, paratracheal, deep cervical, and brachiocephalic lymph nodes. The thyroid gland regulates metabolism in the body.
The document summarizes key anatomical details about the thyroid gland and parathyroid glands. It describes the location, blood supply, drainage, and normal sizes of these glands. It also provides an overview of thyroid physiology including hormone synthesis and regulation via the hypothalamic-pituitary-thyroid axis. The metabolic effects of thyroid hormones are outlined as well.
The carotid triangle is a vascular area in the neck bounded by the omohyoid muscle, digastric muscle, and sternocleidomastoid muscle. It contains the common carotid artery and its branches, internal jugular vein, vagus and other cranial nerves. The common carotid artery divides at the upper border of the thyroid cartilage into the internal and external carotid arteries. The posterior belly of the digastric muscle crosses superficial to the internal jugular vein and carotid vessels in the triangle.
The thyroid gland is a butterfly-shaped endocrine gland located in the front of the neck. It consists of two lobes connected by an isthmus. The lobes extend from the oblique line of the thyroid cartilage to the 6th tracheal ring and lie against the C5-T1 vertebrae. The thyroid gland contains follicular cells that secrete the hormones T3 and T4 and parafollicular C cells that secrete calcitonin. Blood supply comes from the superior and inferior thyroid arteries and lymphatic drainage is to the deep cervical lymph nodes.
The document summarizes the anatomy of the mediastinum. It defines the sternal angle as the joint between the manubrium and sternum. The mediastinum is divided into superior, middle, and posterior sections. The middle mediastinum contains the heart enclosed by the pericardium as well as the great vessels attached to it like the aorta and pulmonary trunk. The document lists the structures found in each section of the mediastinum.
The document provides an anatomical overview of the leg and dorsum of the foot. It describes the bones, muscles, blood vessels, and nerves of the leg and foot. Key points include that the leg contains the tibia and fibula bones, and is divided into anterior, lateral, and posterior compartments by fascia. The main nerves of the leg include the saphenous, superficial peroneal, and lateral cutaneous nerves of the calf. The main artery is the anterior tibial artery. The foot has dorsal and plantar surfaces, and contains bones, muscles like the extensor digitorum brevis, vessels like the dorsalis pedis artery, and nerves.
The thoracic duct is the largest lymphatic vessel in the body. It begins in the abdomen at the lower border of the T12 vertebrae and extends upwards through the posterior and superior mediastinum to the neck. At the C7 vertebral level, it arches laterally and drains into the junction of the left internal jugular and subclavian veins. It drains lymph from the entire body below the diaphragm and left side of the body above the diaphragm, receiving tributaries from lymph nodes and vessels along its course. Injuries or obstructions to the thin-walled thoracic duct can lead to fluid accumulation in the thorax or abdomen.
The thyroid gland is a butterfly-shaped endocrine gland located in the front of the neck. It weighs around 25 grams and is composed of two lateral lobes connected by a narrow isthmus. The gland is situated anterior to the larynx and trachea. It receives blood supply from the superior, inferior, and sometimes thyroid ima arteries, and drains into the superior, middle, and inferior thyroid veins. Lymphatic drainage occurs into the prelaryngeal, pretracheal, paratracheal, deep cervical, and brachiocephalic lymph nodes. The thyroid gland regulates metabolism in the body.
The document summarizes key anatomical details about the thyroid gland and parathyroid glands. It describes the location, blood supply, drainage, and normal sizes of these glands. It also provides an overview of thyroid physiology including hormone synthesis and regulation via the hypothalamic-pituitary-thyroid axis. The metabolic effects of thyroid hormones are outlined as well.
The carotid triangle is a vascular area in the neck bounded by the omohyoid muscle, digastric muscle, and sternocleidomastoid muscle. It contains the common carotid artery and its branches, internal jugular vein, vagus and other cranial nerves. The common carotid artery divides at the upper border of the thyroid cartilage into the internal and external carotid arteries. The posterior belly of the digastric muscle crosses superficial to the internal jugular vein and carotid vessels in the triangle.
The thyroid gland is a butterfly-shaped endocrine gland located in the front of the neck. It consists of two lobes connected by an isthmus. The lobes extend from the oblique line of the thyroid cartilage to the 6th tracheal ring and lie against the C5-T1 vertebrae. The thyroid gland contains follicular cells that secrete the hormones T3 and T4 and parafollicular C cells that secrete calcitonin. Blood supply comes from the superior and inferior thyroid arteries and lymphatic drainage is to the deep cervical lymph nodes.
The document summarizes the anatomy of the mediastinum. It defines the sternal angle as the joint between the manubrium and sternum. The mediastinum is divided into superior, middle, and posterior sections. The middle mediastinum contains the heart enclosed by the pericardium as well as the great vessels attached to it like the aorta and pulmonary trunk. The document lists the structures found in each section of the mediastinum.
The document provides an anatomical overview of the leg and dorsum of the foot. It describes the bones, muscles, blood vessels, and nerves of the leg and foot. Key points include that the leg contains the tibia and fibula bones, and is divided into anterior, lateral, and posterior compartments by fascia. The main nerves of the leg include the saphenous, superficial peroneal, and lateral cutaneous nerves of the calf. The main artery is the anterior tibial artery. The foot has dorsal and plantar surfaces, and contains bones, muscles like the extensor digitorum brevis, vessels like the dorsalis pedis artery, and nerves.
The thyroid gland is the largest endocrine gland located in the neck. It produces three important hormones. Historically, goiters were known since 2700 BC and the thyroid was depicted by Leonardo Da Vinci. Modern thyroid surgery began in the 19th century pioneered by Kocher and Billroth.
The thyroid anatomy includes two lobes connected by an isthmus. It has a true fibrous capsule and false fascial capsule. The recurrent laryngeal nerves pass close to the thyroid and must be identified during surgery to avoid injury. The parathyroid glands are usually found within 1 cm of the inferior thyroid arteries. Proper identification of the recurrent laryngeal nerves, parathyroid glands, and external
The thyroid gland is a butterfly-shaped endocrine gland located in the neck. It consists of two lobes connected by an isthmus. The thyroid derives its blood supply from the superior and inferior thyroid arteries. The recurrent laryngeal nerve passes behind the branches of the inferior thyroid artery, putting it at risk during thyroid surgery. The parathyroid glands are small endocrine glands located posterior to the thyroid that regulate calcium levels. During development, the thyroid begins as a diverticulum in the neck that descends to its final location.
The lower limb can be divided into four main regions: the gluteal region, thigh, leg, and foot. The thigh specifically contains the femur bone and is divided into three fascial compartments by intermuscular septa. The major veins of the lower limb include the superficial great and small saphenous veins and deep femoral and popliteal veins. Lymph from the lower limb drains to either superficial or deep inguinal lymph nodes located in the femoral region.
The diaphragm is a dome-shaped muscle that separates the thoracic and abdominal cavities. It has three openings - the aortic, esophageal, and caval openings. During inspiration, the diaphragm contracts and flattens, increasing the vertical space in the thoracic cavity and causing the lungs to expand and draw in air. During expiration, the diaphragm relaxes and returns to its dome shape, decreasing the vertical space in the thoracic cavity and causing the lungs and chest wall to recoil, pushing air out of the lungs.
The carotid sheath is located in the neck from the base of the skull to the root of the neck. It contains the internal carotid artery, internal jugular vein, vagus nerve, and branches of the sympathetic trunk. The common carotid artery bifurcates into the internal and external carotid arteries around the level of the thyroid cartilage between vertebrae C3 and C4. The structures within the carotid sheath have important relationships that provide pathways for infection spread.
The document provides instructions for marking the locations of major arteries, nerves, and veins on the surface of the upper and lower limbs as well as the thorax. Key structures marked include the brachial, radial, and ulnar arteries in the arm; the femoral, profunda femoris, popliteal, and anterior tibial arteries in the leg; and the axillary, brachial, median, radial, and ulnar nerves in the arm. Major thoracic structures marked are the pulmonary trunk, ascending aorta, aortic arch, and descending aorta.
The neck is the region between the head and chest that contains important structures. It functions to transport the esophagus, trachea, blood vessels, and nerves between the head and chest. The neck is divided into anterior and posterior triangles by the sternocleidomastoid muscle. The anterior triangle contains structures like the thyroid gland, carotid arteries, and jugular veins. It is further divided into the digastric, carotid, and submental triangles which contain additional nerves, muscles and vessels.
The document discusses the deep cervical fascia of the neck, which forms a collar around the neck. It has several layers and modifications, including the investing layer, pretracheal layer, prevertebral layer, carotid sheath, buccopharyngeal fascia, temporal fascia, and pharyngobasilar fascia. Each layer has specific attachments, contents, and clinical relevance. For example, the pretracheal fascia attaches the thyroid gland and allows its movement during swallowing, while the prevertebral fascia can allow spread of infection from the neck to the axilla.
The thoracic duct is the largest lymphatic vessel that drains lymph from most of the body into the venous system in the neck. It begins in the abdomen and ascends through the thorax and neck before terminating at the junction of the left internal jugular and subclavian veins. It receives tributaries along its course that drain lymph from various regions. Damage to the thoracic duct can cause leakage of chyle into body cavities.
The document summarizes the anatomy of the thorax. It contains:
- The thorax is bounded superiorly by the root of the neck and inferiorly by the diaphragm. It contains the heart, lungs, and major blood vessels.
- The mediastinum is the thick soft tissue partition that separates the two pleural cavities and contains the heart and other structures.
- The lungs are enclosed in pleural cavities and separated from each other by the mediastinum.
The parotid gland is a major salivary gland in many animals. In humans, the two parotid glands are present on either side of the mouth and in front of both ears. They are the largest of the salivary glands.
The document discusses the mediastinum, which is the central compartment of the thoracic cavity located between the lungs. It is divided into superior, anterior, middle and posterior mediastinum. The superior mediastinum contains structures such as the thymus gland, great vessels like the superior vena cava and aorta, and nerves like the vagus nerve. The anterior mediastinum contains the thymus gland in children and structures related to the heart. The middle mediastinum contains the heart enclosed in the pericardium. The posterior mediastinum contains the esophagus and descending aorta along with nerves and lymph nodes. Mediastinitis is an infection of the mediastinum which can
The infratemporal fossa is located below the temporal fossa. It is bounded by the ramus of the mandible laterally, the maxilla anteriorly, and the lateral pterygoid plate medially. The infratemporal fossa contains the mandibular nerve, maxillary artery, pterygoid venous plexus, and the medial and lateral pterygoid muscles. The maxillary artery passes through the infratemporal fossa and gives off several branches including the middle meningeal artery, accessory meningeal artery, inferior alveolar artery, and infraorbital artery. It communicates with surrounding areas through gaps in bones and openings in the skull.
This document outlines learning objectives for understanding the thoracic cage and diaphragm. The key points are:
- Describe the boundaries of the thoracic cage, openings of the thorax, and components of the diaphragm including its origin, direction of fibers, blood supply and nerve supply.
- List the structures that pass through openings in the thorax and diaphragm.
- Explain the functions of the diaphragm in respiration and other acts.
- Enumerate conditions related to damage of the phrenic nerve including diaphragmatic paralysis and hernias.
This document discusses the anatomy and physiology of the lungs and pleura. It details the structures of the lungs including the lobes and surfaces. It describes the pleura including its parts and recesses. It discusses applied topics like pneumothorax and proper sites for kidney operations. It also covers the movements of respiration and types that occur at different stages of life.
The document provides information on the structure and components of the thorax. It discusses the bones that make up the thoracic cage including the ribs, sternum, and thoracic vertebrae. It describes the joints that connect these bones, including costovertebral, costotransverse, and sternocostal joints. The document also outlines the landmarks of the thorax, the shape of the thoracic cavity, and the openings at the superior and inferior aspects.
The superior mediastinum is the uppermost division of the mediastinum. It is located posterior to the sternum and anterior to the bodies of the first four thoracic vertebrae. Key structures in the superior mediastinum include the thymus gland, brachiocephalic veins, superior vena cava, arch of aorta and its branches, trachea, esophagus, phrenic nerves, vagus nerves, recurrent laryngeal nerve, thoracic duct, and other smaller structures. The mediastinum is further divided into the superior, inferior anterior, middle and posterior mediastinum.
This document summarizes the anatomy of the thyroid and parathyroid glands. It describes the location, shape, and extent of the thyroid gland. The thyroid has two lobes connected by an isthmus. Each lobe has an apex, base, and surfaces. The document outlines the relationships of the lobes, isthmus, and surfaces to surrounding structures. It also details the blood supply, venous drainage, and lymphatic drainage of the thyroid gland. The location and anatomy of the parathyroid glands are summarized as well.
Development of Thyroid Gland (Special Embryology)Dr. Sherif Fahmy
The thyroid gland develops from endodermal cells in the floor of the pharynx. It begins as a diverticulum on the dorsum of the tongue, which elongates to form the thyroglossal duct. The duct extends downward in front of the hyoid and thyroid cartilage, where it divides into two parts that form the thyroid lobes. The ultimobranchial body contributes parafollicular cells to the thyroid gland. The thyroglossal duct degenerates from the foramen cecum on the tongue down to the hyoid bone. Persistence of parts of the duct can lead to congenital anomalies like lingual thyroid or thyroglossal cysts.
The thyroid gland is a butterfly-shaped endocrine gland located in the neck. It produces thyroid hormones triiodothyronine (T3) and thyroxine (T4) through a process involving iodine uptake, oxidation, and coupling reactions within thyroid follicles. The hormones are stored bound to thyroglobulin and later released into circulation, where they regulate metabolism through negative feedback on the hypothalamus and pituitary gland. The thyroid is supplied by superior and inferior thyroid arteries and drained by superior, middle, and inferior thyroid veins.
The thyroid gland is located in the neck and produces thyroid hormones that regulate metabolism. It consists of two lobes connected by an isthmus. During development it arises from an endodermal diverticulum. The thyroid traps iodine from the blood and uses it along with the amino acid tyrosine to produce the hormones thyroxine (T4) and triiodothyronine (T3) via a series of coupling reactions within the thyroid follicles. T4 makes up 90% of secretion but T3 is the active hormone. Thyroid hormone production is regulated by TSH from the pituitary gland.
The thyroid gland is the largest endocrine gland located in the neck. It produces three important hormones. Historically, goiters were known since 2700 BC and the thyroid was depicted by Leonardo Da Vinci. Modern thyroid surgery began in the 19th century pioneered by Kocher and Billroth.
The thyroid anatomy includes two lobes connected by an isthmus. It has a true fibrous capsule and false fascial capsule. The recurrent laryngeal nerves pass close to the thyroid and must be identified during surgery to avoid injury. The parathyroid glands are usually found within 1 cm of the inferior thyroid arteries. Proper identification of the recurrent laryngeal nerves, parathyroid glands, and external
The thyroid gland is a butterfly-shaped endocrine gland located in the neck. It consists of two lobes connected by an isthmus. The thyroid derives its blood supply from the superior and inferior thyroid arteries. The recurrent laryngeal nerve passes behind the branches of the inferior thyroid artery, putting it at risk during thyroid surgery. The parathyroid glands are small endocrine glands located posterior to the thyroid that regulate calcium levels. During development, the thyroid begins as a diverticulum in the neck that descends to its final location.
The lower limb can be divided into four main regions: the gluteal region, thigh, leg, and foot. The thigh specifically contains the femur bone and is divided into three fascial compartments by intermuscular septa. The major veins of the lower limb include the superficial great and small saphenous veins and deep femoral and popliteal veins. Lymph from the lower limb drains to either superficial or deep inguinal lymph nodes located in the femoral region.
The diaphragm is a dome-shaped muscle that separates the thoracic and abdominal cavities. It has three openings - the aortic, esophageal, and caval openings. During inspiration, the diaphragm contracts and flattens, increasing the vertical space in the thoracic cavity and causing the lungs to expand and draw in air. During expiration, the diaphragm relaxes and returns to its dome shape, decreasing the vertical space in the thoracic cavity and causing the lungs and chest wall to recoil, pushing air out of the lungs.
The carotid sheath is located in the neck from the base of the skull to the root of the neck. It contains the internal carotid artery, internal jugular vein, vagus nerve, and branches of the sympathetic trunk. The common carotid artery bifurcates into the internal and external carotid arteries around the level of the thyroid cartilage between vertebrae C3 and C4. The structures within the carotid sheath have important relationships that provide pathways for infection spread.
The document provides instructions for marking the locations of major arteries, nerves, and veins on the surface of the upper and lower limbs as well as the thorax. Key structures marked include the brachial, radial, and ulnar arteries in the arm; the femoral, profunda femoris, popliteal, and anterior tibial arteries in the leg; and the axillary, brachial, median, radial, and ulnar nerves in the arm. Major thoracic structures marked are the pulmonary trunk, ascending aorta, aortic arch, and descending aorta.
The neck is the region between the head and chest that contains important structures. It functions to transport the esophagus, trachea, blood vessels, and nerves between the head and chest. The neck is divided into anterior and posterior triangles by the sternocleidomastoid muscle. The anterior triangle contains structures like the thyroid gland, carotid arteries, and jugular veins. It is further divided into the digastric, carotid, and submental triangles which contain additional nerves, muscles and vessels.
The document discusses the deep cervical fascia of the neck, which forms a collar around the neck. It has several layers and modifications, including the investing layer, pretracheal layer, prevertebral layer, carotid sheath, buccopharyngeal fascia, temporal fascia, and pharyngobasilar fascia. Each layer has specific attachments, contents, and clinical relevance. For example, the pretracheal fascia attaches the thyroid gland and allows its movement during swallowing, while the prevertebral fascia can allow spread of infection from the neck to the axilla.
The thoracic duct is the largest lymphatic vessel that drains lymph from most of the body into the venous system in the neck. It begins in the abdomen and ascends through the thorax and neck before terminating at the junction of the left internal jugular and subclavian veins. It receives tributaries along its course that drain lymph from various regions. Damage to the thoracic duct can cause leakage of chyle into body cavities.
The document summarizes the anatomy of the thorax. It contains:
- The thorax is bounded superiorly by the root of the neck and inferiorly by the diaphragm. It contains the heart, lungs, and major blood vessels.
- The mediastinum is the thick soft tissue partition that separates the two pleural cavities and contains the heart and other structures.
- The lungs are enclosed in pleural cavities and separated from each other by the mediastinum.
The parotid gland is a major salivary gland in many animals. In humans, the two parotid glands are present on either side of the mouth and in front of both ears. They are the largest of the salivary glands.
The document discusses the mediastinum, which is the central compartment of the thoracic cavity located between the lungs. It is divided into superior, anterior, middle and posterior mediastinum. The superior mediastinum contains structures such as the thymus gland, great vessels like the superior vena cava and aorta, and nerves like the vagus nerve. The anterior mediastinum contains the thymus gland in children and structures related to the heart. The middle mediastinum contains the heart enclosed in the pericardium. The posterior mediastinum contains the esophagus and descending aorta along with nerves and lymph nodes. Mediastinitis is an infection of the mediastinum which can
The infratemporal fossa is located below the temporal fossa. It is bounded by the ramus of the mandible laterally, the maxilla anteriorly, and the lateral pterygoid plate medially. The infratemporal fossa contains the mandibular nerve, maxillary artery, pterygoid venous plexus, and the medial and lateral pterygoid muscles. The maxillary artery passes through the infratemporal fossa and gives off several branches including the middle meningeal artery, accessory meningeal artery, inferior alveolar artery, and infraorbital artery. It communicates with surrounding areas through gaps in bones and openings in the skull.
This document outlines learning objectives for understanding the thoracic cage and diaphragm. The key points are:
- Describe the boundaries of the thoracic cage, openings of the thorax, and components of the diaphragm including its origin, direction of fibers, blood supply and nerve supply.
- List the structures that pass through openings in the thorax and diaphragm.
- Explain the functions of the diaphragm in respiration and other acts.
- Enumerate conditions related to damage of the phrenic nerve including diaphragmatic paralysis and hernias.
This document discusses the anatomy and physiology of the lungs and pleura. It details the structures of the lungs including the lobes and surfaces. It describes the pleura including its parts and recesses. It discusses applied topics like pneumothorax and proper sites for kidney operations. It also covers the movements of respiration and types that occur at different stages of life.
The document provides information on the structure and components of the thorax. It discusses the bones that make up the thoracic cage including the ribs, sternum, and thoracic vertebrae. It describes the joints that connect these bones, including costovertebral, costotransverse, and sternocostal joints. The document also outlines the landmarks of the thorax, the shape of the thoracic cavity, and the openings at the superior and inferior aspects.
The superior mediastinum is the uppermost division of the mediastinum. It is located posterior to the sternum and anterior to the bodies of the first four thoracic vertebrae. Key structures in the superior mediastinum include the thymus gland, brachiocephalic veins, superior vena cava, arch of aorta and its branches, trachea, esophagus, phrenic nerves, vagus nerves, recurrent laryngeal nerve, thoracic duct, and other smaller structures. The mediastinum is further divided into the superior, inferior anterior, middle and posterior mediastinum.
This document summarizes the anatomy of the thyroid and parathyroid glands. It describes the location, shape, and extent of the thyroid gland. The thyroid has two lobes connected by an isthmus. Each lobe has an apex, base, and surfaces. The document outlines the relationships of the lobes, isthmus, and surfaces to surrounding structures. It also details the blood supply, venous drainage, and lymphatic drainage of the thyroid gland. The location and anatomy of the parathyroid glands are summarized as well.
Development of Thyroid Gland (Special Embryology)Dr. Sherif Fahmy
The thyroid gland develops from endodermal cells in the floor of the pharynx. It begins as a diverticulum on the dorsum of the tongue, which elongates to form the thyroglossal duct. The duct extends downward in front of the hyoid and thyroid cartilage, where it divides into two parts that form the thyroid lobes. The ultimobranchial body contributes parafollicular cells to the thyroid gland. The thyroglossal duct degenerates from the foramen cecum on the tongue down to the hyoid bone. Persistence of parts of the duct can lead to congenital anomalies like lingual thyroid or thyroglossal cysts.
The thyroid gland is a butterfly-shaped endocrine gland located in the neck. It produces thyroid hormones triiodothyronine (T3) and thyroxine (T4) through a process involving iodine uptake, oxidation, and coupling reactions within thyroid follicles. The hormones are stored bound to thyroglobulin and later released into circulation, where they regulate metabolism through negative feedback on the hypothalamus and pituitary gland. The thyroid is supplied by superior and inferior thyroid arteries and drained by superior, middle, and inferior thyroid veins.
The thyroid gland is located in the neck and produces thyroid hormones that regulate metabolism. It consists of two lobes connected by an isthmus. During development it arises from an endodermal diverticulum. The thyroid traps iodine from the blood and uses it along with the amino acid tyrosine to produce the hormones thyroxine (T4) and triiodothyronine (T3) via a series of coupling reactions within the thyroid follicles. T4 makes up 90% of secretion but T3 is the active hormone. Thyroid hormone production is regulated by TSH from the pituitary gland.
- The thyroid gland develops from an endodermal diverticulum in the floor of the pharynx that migrates to its final position in the neck.
- It is located in the anterior neck, below the larynx and trachea, and consists of two lobes connected by an isthmus.
- The thyroid gland is highly vascular and receives its blood supply from the superior and inferior thyroid arteries. Its veins drain into the internal jugular and brachiocephalic veins.
This document describes the anatomy of the neck region. It outlines the boundaries, landmarks, triangles, skin, fascia, muscles, vessels and nerves found in the neck. Key structures mentioned include the thyroid gland, larynx, trachea, esophagus, sternocleidomastoid muscle, occipital and supraclavicular triangles, carotid sheath, brachial plexus and spinal accessory nerve.
The document summarizes the surgical anatomy of the thyroid gland. It describes the gland's embryological development from endodermal epithelial cells in the pharynx. It details the thyroid's location in the neck, consisting of two lobes connected by an isthmus. The gland typically weighs 15-25g and produces important hormones. The summary outlines the gland's blood supply from the superior, inferior, and thyroid ima arteries and venous drainage routes. It also notes the gland's relations to surrounding structures like the larynx, trachea and nerves, and that knowledge of its anatomy is important for thyroid surgeries.
This document provides an overview of the anatomy of the thyroid gland, including its development, gross anatomy, blood supply, nerve supply, lymphatic drainage, histology, and applied anatomy. It begins with an introduction to the thyroid gland and its hormone functions. It then discusses the gland's development from an endodermal thickening in the pharynx. The document provides detailed descriptions of the gland's location, shape, size, relations to surrounding structures, capsules, arterial supply, venous drainage, innervation, and histology. It concludes with examples of clinical applications regarding thyroid disorders.
This document describes the boundaries, contents, and structures of the anterior triangle of the neck. It is divided into four triangles based on boundaries: muscular, carotid, digastric, and submental. The carotid triangle contains the common carotid artery and its branches, the internal and external carotid arteries. It also contains the internal jugular vein and nerves like the vagus nerve. The main arteries discussed are the common, internal, and external carotid arteries and their branches. Veins and nerves of the region are also outlined.
This document discusses the anatomy of the thyroid gland. It begins with embryology and covers topics like macroscopic anatomy, blood supply, lymphatics and nerve supply. The thyroid has two lobes joined by an isthmus. It is located in the lower anterior neck and is the largest endocrine gland. The document also describes the microscopic anatomy of thyroid follicles and parafollicular C cells. It notes developmental variations that can occur and provides details on the location and development of the parathyroid glands.
The document summarizes key information about the thyroid and suprarenal glands. It describes the location, structure, blood supply, development, and functions of the thyroid gland. It also discusses common pathologies of the thyroid gland like goiter and hyperthyroidism/hypothyroidism. For the suprarenal glands, it outlines their location in the abdomen, histological structure consisting of the cortex and medulla, hormone production, blood supply and applied clinical implications like Cushing's syndrome and Conn's syndrome.
This document provides an overview of the surgical anatomy of the neck. It describes the boundaries and landmarks of the neck, including the upper and lower borders. It details the structures found in the root of the neck, as well as the mandible, hyoid bone, thyroid cartilage, cricoid cartilage, trachea, and thyroid gland. It discusses the superficial muscles of the neck, including the platysma and sternocleidomastoid muscles. It provides an in-depth description of the fascia of the neck, including the superficial and deep cervical fascia. It outlines the contents and boundaries of the anterior, posterior, and lateral triangles of the neck. Finally, it briefly discusses the cervical lymph nodes.
Cervical Viscera lecture delivered by Saad DattiSadiq787794
The document summarizes the anatomy of the cervical viscera, including the thyroid gland, parathyroid glands, larynx, and trachea. It notes that the cervical viscera are arranged in three layers - endocrine, respiratory, and alimentary. The endocrine layer includes the thyroid and parathyroid glands. The respiratory layer contains the larynx and trachea. The alimentary layer comprises the pharynx and esophagus. It then provides detailed descriptions of the anatomy, blood supply, nerve supply, and functions of the thyroid gland and larynx.
1. The document discusses various deep neck spaces including the retropharyngeal space, danger space, prevertebral space, carotid sheath space, parapharyngeal space, submandibular space, and parotid space.
2. It describes the anatomy, potential sources of infection, clinical presentations, investigations, and management of infections in each space.
3. Key deep neck space infections discussed include retropharyngeal abscess, Ludwig's angina (submandibular space infection), and parotid space infection.
The document provides an in-depth overview of the anatomy of the deep neck spaces. It discusses:
- The 4 compartments that provide longitudinal organization in the neck - visceral, vertebral, and 2 vascular.
- The 3 layers of deep cervical fascia - superficial, middle, and deep layer. Each layer forms boundaries for various spaces.
- The classifications and boundaries of major deep neck spaces - retropharyngeal, danger, prevertebral, and others.
- Potential spaces that can allow spread of infection between layers if compromised.
- Numbered spaces system of Grodinsky and Holyoke which further subdivides the neck spaces.
The thyroid gland is the largest endocrine gland located in the neck. It regulates metabolism, stimulates growth, and plays an important role in calcium homeostasis. The thyroid has two lobes connected by an isthmus and may also have a pyramidal lobe. It is located at the C5-T1 vertebral levels and receives blood supply from the superior and inferior thyroid arteries. The thyroid secretes thyroid hormones T3 and T4 which regulate metabolic rate and calcium levels.
Role Of Surgery In Management of Neck Nodes 2 - Copy.pptxcheshtasharma22
This document provides an overview of the role of surgery in managing neck nodes. It begins with the anatomy of the neck, including layers, spaces, muscles and important nerves. It then discusses the classification of neck lymph nodes into levels. It notes that the most commonly involved nodes are levels II and III. The incidence of occult neck node metastases varies by primary site, being highest for hypopharynx and larynx. The history of neck node management is reviewed, from early radical procedures to more selective approaches developed in the 20th century. In summary, the document outlines neck anatomy and discusses the evaluation and surgical management of neck nodes in head and neck cancer.
1) The external carotid artery arises from the third aortic arch and supplies structures in the head and neck. It bifurcates into the maxillary and superficial temporal arteries.
2) It gives off several branches including the superior thyroid, lingual, facial, occipital, and posterior auricular arteries. The lingual artery supplies the tongue while the facial artery supplies structures in the face.
3) The external carotid artery can be ligated in the carotid triangle below the mandible or in the retromandibular fossa behind the mandible to control bleeding from the head and neck region.
ANATOMY OF LARYNX, VOCAL CORD PALSIES ,.pptxzaaprotta
Anatomy of the Larynx
Cartilaginous Framework and Ligaments:
The larynx consists of several cartilages, both unpaired and paired:
Unpaired Cartilages:
Thyroid Cartilage: The largest laryngeal cartilage, it forms the anterior and lateral portions of the larynx. The prominent anterior projection is commonly known as the “Adam’s apple.”
Cricoid Cartilage: Located below the thyroid cartilage, it forms a complete ring.
Epiglottis: A leaf-shaped cartilage that covers the larynx during swallowing to prevent food aspiration.
Paired Cartilages:
Arytenoid Cartilages: These play a crucial role in vocal fold movement.
Corniculate Cartilages: Sit atop the arytenoids.
Cuneiform Cartilages: Found within the aryepiglottic folds.
the division of abdominal cavities in to different compartments and quadrants by using vertical and horizontal lines, such as supra colic and infra colic compartments , four quadrants, nine quadrants. and the organs present in each compartments respectively.
PERITONEUM AND THE COMPONENTS OF PERITONEUM.pptxDr. sana yaseen
anatomy of peritoneum and the peritoneal cavity. the modification of peritoneum and the structures associated with peritoneum such as, omentum, mesentry mesocolon, epiploic foramen, pouches, peritoneal ligaments, and folds and recesses.
anatomy of larynx, including the spaces associated with larynx the muscles and the paired unpaired cartilages, the attachment of the muscles and the associated functions . true and false vocal cords and the clinical pathology associated with larynx . the blood supply, nerve supply and the lymphatic drainage of the larynx
anterior and posterior triangles of the neck. the boundaries and contents of anterior and posterior triangle. divisions of anterior triangle as carotid triangle, muscular triangle, submental triangle, digastric triangle. division of posterior triangle as occipital triangle, subclavian triangle
dural venous sinus, their location, position and contents passing through important sinuses. their tributaries and drainage. paired unpaired sinuses. and there clinical correlation.
The document provides an overview of the midbrain, including its:
1. Anatomy, with descriptions of its major parts like the cerebral peduncles, substantia nigra, and corpora quadrigemina.
2. Internal structures seen on transverse sections at different levels, such as the cerebral aqueduct, oculomotor and trochlear nerve nuclei.
3. Connections of structures like the superior colliculus and red nucleus.
4. Functions including roles in visual, auditory, and motor pathways through the brainstem.
Anatomy of urinary bladder. surfaces, border of urinary bladder its relation , ligament support, peritoneal relation in male and females, pouches, blood supply of bladder, nerve supply of bladder, true and false ligament of urinary bladder,
gross Anatomy of kidney, description of external and internal structure of kidney, the relation of right and left kidney. difference between right and left kidney, and some clinical abnormalities relate to kidney,
anatomy of suboccipital triangle, bounaries roof and floor of the suboccipital triangle, contents of the triangle, cervical plexus, muscular andd sensory branches of cervical plexus
anatomy of hard palate an soft palate. boundaries of hard and soft palate, blood supply, nerve supply .
osteology of hard palate, muscles of soft palate. origin, insertion of muscles of soft palate, action of muscles of soft palate, pasavants ridge
This document discusses neural tube defects (NTDs), which occur early in pregnancy when the neural tubes fail to close properly. It describes different types of NTDs including spina bifida, anencephaly, and exencephaly. Spina bifida can be occulta, cystica, or myelomeningocele depending on whether the spinal cord or meninges protrude out. Anencephaly and exencephaly involve failure of the cranial neural tube to close. Risk factors include genetics and lack of folic acid. Prenatal screening can detect some NTDs but early fetal surgery is also being studied. Taking folic acid before and during pregnancy can help prevent NTDs.
Breast cancer: Post menopausal endocrine therapyDr. Sumit KUMAR
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
DECLARATION OF HELSINKI - History and principlesanaghabharat01
This SlideShare presentation provides a comprehensive overview of the Declaration of Helsinki, a foundational document outlining ethical guidelines for conducting medical research involving human subjects.
Histololgy of Female Reproductive System.pptxAyeshaZaid1
Dive into an in-depth exploration of the histological structure of female reproductive system with this comprehensive lecture. Presented by Dr. Ayesha Irfan, Assistant Professor of Anatomy, this presentation covers the Gross anatomy and functional histology of the female reproductive organs. Ideal for students, educators, and anyone interested in medical science, this lecture provides clear explanations, detailed diagrams, and valuable insights into female reproductive system. Enhance your knowledge and understanding of this essential aspect of human biology.
5-hydroxytryptamine or 5-HT or Serotonin is a neurotransmitter that serves a range of roles in the human body. It is sometimes referred to as the happy chemical since it promotes overall well-being and happiness.
It is mostly found in the brain, intestines, and blood platelets.
5-HT is utilised to transport messages between nerve cells, is known to be involved in smooth muscle contraction, and adds to overall well-being and pleasure, among other benefits. 5-HT regulates the body's sleep-wake cycles and internal clock by acting as a precursor to melatonin.
It is hypothesised to regulate hunger, emotions, motor, cognitive, and autonomic processes.
How to Control Your Asthma Tips by gokuldas hospital.Gokuldas Hospital
Respiratory issues like asthma are the most sensitive issue that is affecting millions worldwide. It hampers the daily activities leaving the body tired and breathless.
The key to a good grip on asthma is proper knowledge and management strategies. Understanding the patient-specific symptoms and carving out an effective treatment likewise is the best way to keep asthma under control.
Promoting Wellbeing - Applied Social Psychology - Psychology SuperNotesPsychoTech Services
A proprietary approach developed by bringing together the best of learning theories from Psychology, design principles from the world of visualization, and pedagogical methods from over a decade of training experience, that enables you to: Learn better, faster!
Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
Osteoporosis - Definition , Evaluation and Management .pdfJim Jacob Roy
Osteoporosis is an increasing cause of morbidity among the elderly.
In this document , a brief outline of osteoporosis is given , including the risk factors of osteoporosis fractures , the indications for testing bone mineral density and the management of osteoporosis
These lecture slides, by Dr Sidra Arshad, offer a simplified look into the mechanisms involved in the regulation of respiration:
Learning objectives:
1. Describe the organisation of respiratory center
2. Describe the nervous control of inspiration and respiratory rhythm
3. Describe the functions of the dorsal and respiratory groups of neurons
4. Describe the influences of the Pneumotaxic and Apneustic centers
5. Explain the role of Hering-Breur inflation reflex in regulation of inspiration
6. Explain the role of central chemoreceptors in regulation of respiration
7. Explain the role of peripheral chemoreceptors in regulation of respiration
8. Explain the regulation of respiration during exercise
9. Integrate the respiratory regulatory mechanisms
10. Describe the Cheyne-Stokes breathing
Study Resources:
1. Chapter 42, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 36, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 13, Human Physiology by Lauralee Sherwood, 9th edition
Co-Chairs, Val J. Lowe, MD, and Cyrus A. Raji, MD, PhD, prepared useful Practice Aids pertaining to Alzheimer’s disease for this CME/AAPA activity titled “Alzheimer’s Disease Case Conference: Gearing Up for the Expanding Role of Neuroradiology in Diagnosis and Treatment.” For the full presentation, downloadable Practice Aids, and complete CME/AAPA information, and to apply for credit, please visit us at https://bit.ly/3PvVY25. CME/AAPA credit will be available until June 28, 2025.
Kosmoderma Academy, a leading institution in the field of dermatology and aesthetics, offers comprehensive courses in cosmetology and trichology. Our specialized courses on PRP (Hair), DR+Growth Factor, GFC, and Qr678 are designed to equip practitioners with advanced skills and knowledge to excel in hair restoration and growth treatments.
2. • Endocrine gland
• Endodermal in origin
• Location: front of lower part of larynx and upper part of
trachea (anterior to the junction of the thyroid and cricoid
cartilages ).
• Weigh: 25gm
6. Parts
• Composed of
– 2 lobes joined together by isthmus.
• In some people, the gland has an additional lobe, called
the pyramidal lobe, that ascends from the left side of
the isthmus.
• The pyramidal lobe is an embryological remnant of the
path of descent of the thyroid primordium from its origin
in the forming tongue by way of the thyroglossal duct.
– 2 capsules (true and false)
• Each lobes are composed of :
– 3surfaces
– 2borders
– Apex
– Base
7. TRUE CAPSULE: is peripheral condensation of
connective tissue surrounding gland. Throwing into
septa and lobules.
FALSE CAPSULE: derived from pretracheal layer
of deep fascia.
• Moves during deglutition and speech.
• It is thick on inner surface of gland where it
forms suspensory ligament of berry, connects
lobe of thyroid to cricoid cartilage.
8.
9.
10.
11. SURFACES
Lateral:
Is lateral and forward
Covered by: skin, fascia, sternothyroid, sternohyoid,
omohyoid, sternocleidomastoid muscle
Medial:
Lies over thyroid & cricoid cartilage, trachea and
esophagus.
Inferior constrictor of pharynx, recurrent laryngeal nerve
and external laryngeal nerve.
Posterior:
• Carotid sheath and its contents
12.
13. BORDERS
Anterior:
between lateral and medial surface.
Relation: branch of superior thyroid artery.
Posterior:
between posterior and medial surface
Relation: inferior thyroid artery
Parathyroid gland
Thoracic duct
14. • APEX: upper end extends up to oblique line of
thyroid cartilage
• Base: lower end extends up to 5-6 tracheal ring
or T1 vertebrae.
15.
16. ISTHMUS
• lies in front of 2-4 tracheal ring
• Anteriorly related to: skin, fascia, sternohyoid,
sternothyroid muscles.
• Upper border: finger like projection (pyramidal
lobe) attach to hyoid bone by levator of thyroid
gland
17.
18. ARTERIAL SUPPLY
• Superior thyroid artery: branch of ECA-
upper border of gland and isthmus
• Inferior thyroid artery: branch of
thyrocervical trunk- lower pole of gland
22. FUNCTIONS OF THYROID GLAND
• Brain maturation
• Bone growth
• Beta adrenergic effects
• Increase rate of Basal metabolism
• Another hormone, calcitonin, aids in
decreasing blood calcium levels and
facilitates the storage of calcium in bones
23. • GOITER: is increase in the size of thyroid
gland.
• Hyperthyroidism:
• Hypothyroidism: