The parasitic protist Trypanosoma brucei is the causative agent of Human African
Trypanosomiasis, also known as sleeping sickness. The parasite enters the blood via the bite of
the tsetse fly where it is wholly reliant on glycolysis for the production of ATP. The bloodstream
form of T. brucei has evolved to rely on the high ( 5 mM ) levels of glucose available in host
blood as fuel. In this stage of its life cycle, the parasite mitochondrion is highly compromised
and cannot carry out oxidative phosphorylation and T , brucel exclusively uses glycolysis as the
sole source of ATP production. T. brucei phosphofructokinase (TbPFK) is located in
peroxisome-related organelles called glycosomes and carries out the third step in the glycolytic
pathway, phosphorylating fructose 6-phosphate (F6P) to give fructose 1,6-bisphosphate (F16BP).
Low sequence identity of 20% with the three human isoforms (hPFK-M, hPFK-L and hPFK.P)
makes this enzyme a key drug larget. Answer the following questions. Remember that your
typed response must match the provided options to be scored correctly and receive credit. - What
type of microscopy was used to produce the image of Thpanosome brucei above? SEM / TEM /
Bright Field / Dark Field / Phase Contrast I Fluorescence. - Typanosome brucei would be
classitied as a prokaryote / eukaryote - 11. Thyanosoma brucei uses glyoolyais as the sole sourco
of ATP production, then you expect ATP to be produced by oxidative f photo / substrate-level
phosphorylation. - TopFK is an example of a(n) hydrolase I isomerase / Bgase I lyase I
oxidoreductase I tanaferase - The Mg 2 + in this reacton serves as a(n) apoenryme I holoenayme
/ cofactor / coenryme / product.
PPT presentation is on HMP Shunt and regulations of microbial metabolism.
The Hexose Monophosphate Pathway also called the Phosphogluconate Pathway and the Pentose Phosphate Pathway.
This pathway parallel to glycolysis.
This pathway is important for formation of NADPH and Pentose as well as ribose-5-phosphate.
PPT presentation is on HMP Shunt and regulations of microbial metabolism.
The Hexose Monophosphate Pathway also called the Phosphogluconate Pathway and the Pentose Phosphate Pathway.
This pathway parallel to glycolysis.
This pathway is important for formation of NADPH and Pentose as well as ribose-5-phosphate.
First aid for usmle step 1 with uworld and nbme notes sampleusmlematerialsnet
First Aid For USMLE Step 1 with Uworld and NBME Notes
Download Full book from > usmlematerials.net
Pages: 798
Series: First Aid for the USMLE Step 1
NBMEs and Uworld Notes are added to this file.
Protein is a macronutrient that is essential to building muscle mass. It is commonly found in animal products, though is also present in other sources, such as nuts and legumes. There are three macronutrients: protein, fats and carbohydrates. Macronutrients provide calories, or energy.
The shikimate pathway was discovered as the biosynthetic route to the aromatic amino acids phenylalanine, tyrosine, and tryptophan.
This pathway has been found only in microorganisms and plants. Phenylalanine and tryptophan are essential components of animal diets, and animals synthesize tyrosine in a single step from phenylalanine.
1. Sulphonation metabolism- introduction, types of sulphate transferases, reactions, summary
2. EMT pathways explaining metastasis in cancer and molecular pathways
3. Thank you
Malaria vaccines cum antimalaria drugs, by bdollarbernard bahaah
This presentation slides give an upto date information on antimalaria drugs and vaccines. It can be used for academic purpose or some other purpose. It highlights some of the successes and potentials of antimalaria drugs.
The results of Mendel's cross (breeding experiment) of two phenotypica.pdfRobertXhxWalkerv
The results of Mendel's cross (breeding experiment) of two phenotypically different plants of the
P generation established what important genetic principle (law)? Law of Dominance Law of
Independent Assortment Law of Mutation Law of Segregation What must be true of the F 1
generation that came from Mendel's cross (breeding experiment) of two phenotypically different
plants of the P generation? F1 plants are sterile F1 plants are heterozyogous F1 plants are
homozygous F1 plants are true-breeding The results of Mendel's dihybrid cross (breeding
experiment) of two plants of the F 1 generation established what important genetic principle
(law)? Law of Independent Assortment Law of Dominance Law of Mutation Law of Segregation.
The resting potential of neurons is negative because a- there is an ex.pdfRobertXhxWalkerv
The resting potential of neurons is negative because a. there is an excess of K + outside of the
cell at rest. b. at rest there is an excess of K + outside of the cell, and the membrane is permeable
chiefly to K + . c. at rest there is an excess of K + inside the cell, and the membrane is permeable
chiefly to K + . d. at rest there is an excess of K + inside the cell, but the membrane is permeable
to all ions. e. there is an excess of Cl - ions outside of the cell at rest..
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Protein is a macronutrient that is essential to building muscle mass. It is commonly found in animal products, though is also present in other sources, such as nuts and legumes. There are three macronutrients: protein, fats and carbohydrates. Macronutrients provide calories, or energy.
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hospital. This has important implicatices when estimating just how disruptive Omicron will be in
termes of deaths. bospitalizations and work and school interruptions. To assess the future burden
of a variant like Oanicron, epidemiologists tike myself often turn to mathematical modeling and
projection. The idea is to use a cuenpoter-based representation of bow the virus spreads to
simulate potential future outcomes. It is important for modelers to explore the unisnowns around
Covid. For instance, evidence indicates that Omicron is more. for the past two years, there are
clear indications this wave will differ substantially froms previous ones. The recond number of
cases in the United States and globally is largely because Omicron is more contagous than other
variant: and las a greater ahality to evade immanity to iafection. At the same time, early evidence
indicates that it's less common for people infected with Omicron to experience severe disezse
and end up in the bospital. This has important implications when estimating just bow disruptive
Omicron wilt be in terms of deaths. hospitalizations and work and school interruptions. To assess
the future burten of a variant lake Omicron, epidemsologists like myself often turn to
mathematical modeling and projection. The idea is to use a computer based representation of
how the virus spreads to simulate potential future cutcomes. It is important for modelers to
explore the unknowns around Covid. For instance, evidence indicates that Omicron is more
transmissible than the Delta variant, but by bow much? Ey incorporating uncertainties into our
models, we damt merely project a single outcoene. Instead, we creale a distribution of autcomes,
mach like the cone af uncertainty ased fine a hurricane landfall forecast. Projecting the Covi-19
burden is also more difticutt bow because of the December holidays. Repo.
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The Bionomial is a more complex calculation used when you have multiple events AND
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S! T!
BTW= s + t = n and p+q = 1
Here are problems that use this rule:
5. John and Mary each have sisters with cystic fibrosis. They would like to marry and have
children, but are concerned that they too may have a child with cystic fibrosis. Cystic fibrosis is
an autosomal recessive disease located on chromosome 7. If John and Mary are each
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A. Having 2 normal children and 2 affected children in any order?
B. Having 3 normal children and 2 affected children in any order?.
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This is a genetic question:
4. John and Mary each have sisters with cystic fibrosis. They would like to marry and have
children, but are concerned that they too may have a child with cystic fibrosis. Cystic fibrosis is
an autosomal recessive disease located on chromosome 7. If John and Mary are each
heterozygous for cystic fibrosis what is the probability of:
A. Having a child with cystic fibrosis?
B. Having two children that are affected?
C. Having 4 children with normal phenotypes?.
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organisms are animals, except for the bacteria. In this food web, the relationship between the
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the figure) and a heteromorphic pair ( 1 in the figure)? a) The author was the first to demonstrate
that chromosomes move to the spindle poles during meiosis. This was the first time that a
microscope was used to observe chromosomes in the cells that form gametes. The author used
these chromosomes with different shapes to arrive at the terms "centromere" and "telomere",
since the unpaired chromosome is in the center of the figure and the heteromorphic pair are at
one end. The author observed that the unpaired chromosome always segregated with the same
non-identical chromosomes. This was cytological evidence that chromosomes do not assort
independently in the first meiotic division. The author saw that the unpaired chromosome
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This was early cytological evidence that chromosomes assort independently in the first meiotic
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Thirty-nine percent of U.S. adults have very litle confidence in newspapers. You randomly select
nithe U.S. adults. Find the probability that the number who have very litile confidence in
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There are
9
streets to be named after
9
tree types.
Ash, Birch, Cedar, Elm, Maple, Oak, Pine, Spruce, and Willow.
A city planner randomly selects the street names from the list of
9
tree types.
Compute the probability of each of the following events.
Event A: The first four streets are Pine, Willow, Elm, and Maple, without regard to order.
Event B: The first street is Pine, followed by Cedar then Willow, and then Oak.
Write your answers as fractions in simplest form.
PA
=
PB
=
PA =
PB =
.
A workshop hosted by the South African Journal of Science aimed at postgraduate students and early career researchers with little or no experience in writing and publishing journal articles.
Synthetic Fiber Construction in lab .pptxPavel ( NSTU)
Synthetic fiber production is a fascinating and complex field that blends chemistry, engineering, and environmental science. By understanding these aspects, students can gain a comprehensive view of synthetic fiber production, its impact on society and the environment, and the potential for future innovations. Synthetic fibers play a crucial role in modern society, impacting various aspects of daily life, industry, and the environment. ynthetic fibers are integral to modern life, offering a range of benefits from cost-effectiveness and versatility to innovative applications and performance characteristics. While they pose environmental challenges, ongoing research and development aim to create more sustainable and eco-friendly alternatives. Understanding the importance of synthetic fibers helps in appreciating their role in the economy, industry, and daily life, while also emphasizing the need for sustainable practices and innovation.
Safalta Digital marketing institute in Noida, provide complete applications that encompass a huge range of virtual advertising and marketing additives, which includes search engine optimization, virtual communication advertising, pay-per-click on marketing, content material advertising, internet analytics, and greater. These university courses are designed for students who possess a comprehensive understanding of virtual marketing strategies and attributes.Safalta Digital Marketing Institute in Noida is a first choice for young individuals or students who are looking to start their careers in the field of digital advertising. The institute gives specialized courses designed and certification.
for beginners, providing thorough training in areas such as SEO, digital communication marketing, and PPC training in Noida. After finishing the program, students receive the certifications recognised by top different universitie, setting a strong foundation for a successful career in digital marketing.
2024.06.01 Introducing a competency framework for languag learning materials ...Sandy Millin
http://sandymillin.wordpress.com/iateflwebinar2024
Published classroom materials form the basis of syllabuses, drive teacher professional development, and have a potentially huge influence on learners, teachers and education systems. All teachers also create their own materials, whether a few sentences on a blackboard, a highly-structured fully-realised online course, or anything in between. Despite this, the knowledge and skills needed to create effective language learning materials are rarely part of teacher training, and are mostly learnt by trial and error.
Knowledge and skills frameworks, generally called competency frameworks, for ELT teachers, trainers and managers have existed for a few years now. However, until I created one for my MA dissertation, there wasn’t one drawing together what we need to know and do to be able to effectively produce language learning materials.
This webinar will introduce you to my framework, highlighting the key competencies I identified from my research. It will also show how anybody involved in language teaching (any language, not just English!), teacher training, managing schools or developing language learning materials can benefit from using the framework.
Exploiting Artificial Intelligence for Empowering Researchers and Faculty, In...Dr. Vinod Kumar Kanvaria
Exploiting Artificial Intelligence for Empowering Researchers and Faculty,
International FDP on Fundamentals of Research in Social Sciences
at Integral University, Lucknow, 06.06.2024
By Dr. Vinod Kumar Kanvaria
A Strategic Approach: GenAI in EducationPeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
Macroeconomics- Movie Location
This will be used as part of your Personal Professional Portfolio once graded.
Objective:
Prepare a presentation or a paper using research, basic comparative analysis, data organization and application of economic information. You will make an informed assessment of an economic climate outside of the United States to accomplish an entertainment industry objective.
The parasitic protist Trypanosoma brucei is the causative agent of Hum.pdf
1. The parasitic protist Trypanosoma brucei is the causative agent of Human African
Trypanosomiasis, also known as sleeping sickness. The parasite enters the blood via the bite of
the tsetse fly where it is wholly reliant on glycolysis for the production of ATP. The bloodstream
form of T. brucei has evolved to rely on the high ( 5 mM ) levels of glucose available in host
blood as fuel. In this stage of its life cycle, the parasite mitochondrion is highly compromised
and cannot carry out oxidative phosphorylation and T , brucel exclusively uses glycolysis as the
sole source of ATP production. T. brucei phosphofructokinase (TbPFK) is located in
peroxisome-related organelles called glycosomes and carries out the third step in the glycolytic
pathway, phosphorylating fructose 6-phosphate (F6P) to give fructose 1,6-bisphosphate (F16BP).
Low sequence identity of 20% with the three human isoforms (hPFK-M, hPFK-L and hPFK.P)
makes this enzyme a key drug larget. Answer the following questions. Remember that your
typed response must match the provided options to be scored correctly and receive credit. - What
type of microscopy was used to produce the image of Thpanosome brucei above? SEM / TEM /
Bright Field / Dark Field / Phase Contrast I Fluorescence. - Typanosome brucei would be
classitied as a prokaryote / eukaryote - 11. Thyanosoma brucei uses glyoolyais as the sole sourco
of ATP production, then you expect ATP to be produced by oxidative f photo / substrate-level
phosphorylation. - TopFK is an example of a(n) hydrolase I isomerase / Bgase I lyase I
oxidoreductase I tanaferase - The Mg 2 + in this reacton serves as a(n) apoenryme I holoenayme
/ cofactor / coenryme / product
