This training slide set about the National Flu vaccination programme 2017-2018 is intended for healthcare practitioners and includes detailed information on:
• the background of the programme
• vaccine handling, administration and constituents
• eligibility and resource
For additional guidance on delivering the programme please visit https://www.gov.uk/government/collections/annual-flu-programme
National Childhood Flu Immunisation Programme 2017-18 - training for healthca...Public Health England
This training slide set about the National Flu vaccination programme 2017-2018 is intended for healthcare practitioners and includes detailed information on:
• the background of the programme
• vaccine handling, administration and constituents
• eligibility and resource
For additional guidance on delivering the programme please visit https://www.gov.uk/government/collections/annual-flu-programme
This slide deck contains Information for healthcare practitioners about the introduction of the hexavalent vaccine into the routine infant immunisation programme. For more information visit: https://www.gov.uk/government/publications/hexavalent-combination-vaccine-programme-guidance
National Childhood Flu Immunisation Programme 2017-18 - training for healthca...Public Health England
This training slide set about the National Flu vaccination programme 2017-2018 is intended for healthcare practitioners and includes detailed information on:
• the background of the programme
• vaccine handling, administration and constituents
• eligibility and resource
For additional guidance on delivering the programme please visit https://www.gov.uk/government/collections/annual-flu-programme
This slide deck contains Information for healthcare practitioners about the introduction of the hexavalent vaccine into the routine infant immunisation programme. For more information visit: https://www.gov.uk/government/publications/hexavalent-combination-vaccine-programme-guidance
Universal Immunization Program is a vaccination program launched by the Government of India in 1985.
It became a part of Child Survival and Safe Motherhood Program in 1992 and is currently one of the key areas under National Rural Health Mission(NRHM) since 2005.
Program consists of vaccination for 12 diseases -
Tuberculosis
Diphtheria
Pertussis
Tetanus,
Poliomyelitis,
Measles,
Hepatitis B,
Diarrhea,
Japanese-Encephalitis,
Rubella,
Pneumonia
Pneumococcal diseases
This slides helps to know the history of Immunisation along with the present programs & conditions. This also consists of Immunisation Schedule of Nepal along with features of some vaccines.
At the four front of flu vaccination - Quadrivalent Flu Vaccination in India ...Gaurav Gupta
Is flu vaccination needed in India? Is there any benefits of Quadrivalent Flu vaccination over Trivalent Flu vaccination? Any safety & efficacy data about Vaxiflu 4 by Zydus Vaccines. All discussed in a Presentation in Panchkula, in September 2019
In order to ensure the control, eradication and elimination of diseases, routine immunization is extremely important. Since the Indian climatic condition is extremely disease-prone, one needs to embrace the latest advancements which have ushered into the vaccine and immunization arena. Vaccination initiatives can be made more effective through a routine immunization program in India.
via : https://www.itsu.org.in/
Influenza - History, Vaccination, and Public HealthLouise O' Flynn
A presentation exploring the history of Influenza, vaccination for influenza in Ireland, and the impact of Influenza on Public Health, public policy, and health promotion initiatives.
Authors: Tighearnan Corcoran, Stephanie Mulcair, Louise O' Flynn.
Universal Immunization Program is a vaccination program launched by the Government of India in 1985.
It became a part of Child Survival and Safe Motherhood Program in 1992 and is currently one of the key areas under National Rural Health Mission(NRHM) since 2005.
Program consists of vaccination for 12 diseases -
Tuberculosis
Diphtheria
Pertussis
Tetanus,
Poliomyelitis,
Measles,
Hepatitis B,
Diarrhea,
Japanese-Encephalitis,
Rubella,
Pneumonia
Pneumococcal diseases
This slides helps to know the history of Immunisation along with the present programs & conditions. This also consists of Immunisation Schedule of Nepal along with features of some vaccines.
At the four front of flu vaccination - Quadrivalent Flu Vaccination in India ...Gaurav Gupta
Is flu vaccination needed in India? Is there any benefits of Quadrivalent Flu vaccination over Trivalent Flu vaccination? Any safety & efficacy data about Vaxiflu 4 by Zydus Vaccines. All discussed in a Presentation in Panchkula, in September 2019
In order to ensure the control, eradication and elimination of diseases, routine immunization is extremely important. Since the Indian climatic condition is extremely disease-prone, one needs to embrace the latest advancements which have ushered into the vaccine and immunization arena. Vaccination initiatives can be made more effective through a routine immunization program in India.
via : https://www.itsu.org.in/
Influenza - History, Vaccination, and Public HealthLouise O' Flynn
A presentation exploring the history of Influenza, vaccination for influenza in Ireland, and the impact of Influenza on Public Health, public policy, and health promotion initiatives.
Authors: Tighearnan Corcoran, Stephanie Mulcair, Louise O' Flynn.
Influenza vaccines or flu shots protect against influenza. A new version of the vaccine is developed twice a year as the influenza virus rapidly changes. Their effectiveness varies from year to year, most provide modest to high protection against influenza.
The Autism local self-assessment is a periodic exercise in which local autism strategy groups are asked to review their progress in implementing the government’s Autism Strategy in partnership with local residents with autism and their family carers. The sets of PowerPoint slides in this package, one for each of the former Government Office Regions in England, display the responses of the local authorities within the region to the questions in the Self-Assessment.
PowerPoint slides, one for each of the former Government Office Regions in England, display the responses of the local authorities within the region to the questions in the Self-Assessment. They are intended primarily to support local discussions.
PowerPoint slides, one for each of the former Government Office Regions in England, display the responses of the local authorities within the region to the questions in the Self-Assessment. They are intended primarily to support local discussions.
PowerPoint slides, one for each of the former Government Office Regions in England, display the responses of the local authorities within the region to the questions in the Self-Assessment. They are intended primarily to support local discussions.
CHAPTER 1 SEMESTER V PREVENTIVE-PEDIATRICS.pdfSachin Sharma
This content provides an overview of preventive pediatrics. It defines preventive pediatrics as preventing disease and promoting children's physical, mental, and social well-being to achieve positive health. It discusses antenatal, postnatal, and social preventive pediatrics. It also covers various child health programs like immunization, breastfeeding, ICDS, and the roles of organizations like WHO, UNICEF, and nurses in preventive pediatrics.
CHAPTER 1 SEMESTER V - ROLE OF PEADIATRIC NURSE.pdfSachin Sharma
Pediatric nurses play a vital role in the health and well-being of children. Their responsibilities are wide-ranging, and their objectives can be categorized into several key areas:
1. Direct Patient Care:
Objective: Provide comprehensive and compassionate care to infants, children, and adolescents in various healthcare settings (hospitals, clinics, etc.).
This includes tasks like:
Monitoring vital signs and physical condition.
Administering medications and treatments.
Performing procedures as directed by doctors.
Assisting with daily living activities (bathing, feeding).
Providing emotional support and pain management.
2. Health Promotion and Education:
Objective: Promote healthy behaviors and educate children, families, and communities about preventive healthcare.
This includes tasks like:
Administering vaccinations.
Providing education on nutrition, hygiene, and development.
Offering breastfeeding and childbirth support.
Counseling families on safety and injury prevention.
3. Collaboration and Advocacy:
Objective: Collaborate effectively with doctors, social workers, therapists, and other healthcare professionals to ensure coordinated care for children.
Objective: Advocate for the rights and best interests of their patients, especially when children cannot speak for themselves.
This includes tasks like:
Communicating effectively with healthcare teams.
Identifying and addressing potential risks to child welfare.
Educating families about their child's condition and treatment options.
4. Professional Development and Research:
Objective: Stay up-to-date on the latest advancements in pediatric healthcare through continuing education and research.
Objective: Contribute to improving the quality of care for children by participating in research initiatives.
This includes tasks like:
Attending workshops and conferences on pediatric nursing.
Participating in clinical trials related to child health.
Implementing evidence-based practices into their daily routines.
By fulfilling these objectives, pediatric nurses play a crucial role in ensuring the optimal health and well-being of children throughout all stages of their development.
Deep Leg Vein Thrombosis (DVT): Meaning, Causes, Symptoms, Treatment, and Mor...The Lifesciences Magazine
Deep Leg Vein Thrombosis occurs when a blood clot forms in one or more of the deep veins in the legs. These clots can impede blood flow, leading to severe complications.
CRISPR-Cas9, a revolutionary gene-editing tool, holds immense potential to reshape medicine, agriculture, and our understanding of life. But like any powerful tool, it comes with ethical considerations.
Unveiling CRISPR: This naturally occurring bacterial defense system (crRNA & Cas9 protein) fights viruses. Scientists repurposed it for precise gene editing (correction, deletion, insertion) by targeting specific DNA sequences.
The Promise: CRISPR offers exciting possibilities:
Gene Therapy: Correcting genetic diseases like cystic fibrosis.
Agriculture: Engineering crops resistant to pests and harsh environments.
Research: Studying gene function to unlock new knowledge.
The Peril: Ethical concerns demand attention:
Off-target Effects: Unintended DNA edits can have unforeseen consequences.
Eugenics: Misusing CRISPR for designer babies raises social and ethical questions.
Equity: High costs could limit access to this potentially life-saving technology.
The Path Forward: Responsible development is crucial:
International Collaboration: Clear guidelines are needed for research and human trials.
Public Education: Open discussions ensure informed decisions about CRISPR.
Prioritize Safety and Ethics: Safety and ethical principles must be paramount.
CRISPR offers a powerful tool for a better future, but responsible development and addressing ethical concerns are essential. By prioritizing safety, fostering open dialogue, and ensuring equitable access, we can harness CRISPR's power for the benefit of all. (2998 characters)
The dimensions of healthcare quality refer to various attributes or aspects that define the standard of healthcare services. These dimensions are used to evaluate, measure, and improve the quality of care provided to patients. A comprehensive understanding of these dimensions ensures that healthcare systems can address various aspects of patient care effectively and holistically. Dimensions of Healthcare Quality and Performance of care include the following; Appropriateness, Availability, Competence, Continuity, Effectiveness, Efficiency, Efficacy, Prevention, Respect and Care, Safety as well as Timeliness.
ICH Guidelines for Pharmacovigilance.pdfNEHA GUPTA
The "ICH Guidelines for Pharmacovigilance" PDF provides a comprehensive overview of the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) guidelines related to pharmacovigilance. These guidelines aim to ensure that drugs are safe and effective for patients by monitoring and assessing adverse effects, ensuring proper reporting systems, and improving risk management practices. The document is essential for professionals in the pharmaceutical industry, regulatory authorities, and healthcare providers, offering detailed procedures and standards for pharmacovigilance activities to enhance drug safety and protect public health.
Telehealth Psychology Building Trust with Clients.pptxThe Harvest Clinic
Telehealth psychology is a digital approach that offers psychological services and mental health care to clients remotely, using technologies like video conferencing, phone calls, text messaging, and mobile apps for communication.
Defecation
Normal defecation begins with movement in the left colon, moving stool toward the anus. When stool reaches the rectum, the distention causes relaxation of the internal sphincter and an awareness of the need to defecate. At the time of defecation, the external sphincter relaxes, and abdominal muscles contract, increasing intrarectal pressure and forcing the stool out
The Valsalva maneuver exerts pressure to expel faeces through a voluntary contraction of the abdominal muscles while maintaining forced expiration against a closed airway. Patients with cardiovascular disease, glaucoma, increased intracranial pressure, or a new surgical wound are at greater risk for cardiac dysrhythmias and elevated blood pressure with the Valsalva maneuver and need to avoid straining to pass the stool.
Normal defecation is painless, resulting in passage of soft, formed stool
CONSTIPATION
Constipation is a symptom, not a disease. Improper diet, reduced fluid intake, lack of exercise, and certain medications can cause constipation. For example, patients receiving opiates for pain after surgery often require a stool softener or laxative to prevent constipation. The signs of constipation include infrequent bowel movements (less than every 3 days), difficulty passing stools, excessive straining, inability to defecate at will, and hard feaces
IMPACTION
Fecal impaction results from unrelieved constipation. It is a collection of hardened feces wedged in the rectum that a person cannot expel. In cases of severe impaction the mass extends up into the sigmoid colon.
DIARRHEA
Diarrhea is an increase in the number of stools and the passage of liquid, unformed feces. It is associated with disorders affecting digestion, absorption, and secretion in the GI tract. Intestinal contents pass through the small and large intestine too quickly to allow for the usual absorption of fluid and nutrients. Irritation within the colon results in increased mucus secretion. As a result, feces become watery, and the patient is unable to control the urge to defecate. Normally an anal bag is safe and effective in long-term treatment of patients with fecal incontinence at home, in hospice, or in the hospital. Fecal incontinence is expensive and a potentially dangerous condition in terms of contamination and risk of skin ulceration
HEMORRHOIDS
Hemorrhoids are dilated, engorged veins in the lining of the rectum. They are either external or internal.
FLATULENCE
As gas accumulates in the lumen of the intestines, the bowel wall stretches and distends (flatulence). It is a common cause of abdominal fullness, pain, and cramping. Normally intestinal gas escapes through the mouth (belching) or the anus (passing of flatus)
FECAL INCONTINENCE
Fecal incontinence is the inability to control passage of feces and gas from the anus. Incontinence harms a patient’s body image
PREPARATION AND GIVING OF LAXATIVESACCORDING TO POTTER AND PERRY,
An enema is the instillation of a solution into the rectum and sig
Explore our infographic on 'Essential Metrics for Palliative Care Management' which highlights key performance indicators crucial for enhancing the quality and efficiency of palliative care services.
This visual guide breaks down important metrics across four categories: Patient-Centered Metrics, Care Efficiency Metrics, Quality of Life Metrics, and Staff Metrics. Each section is designed to help healthcare professionals monitor and improve care delivery for patients facing serious illnesses. Understand how to implement these metrics in your palliative care practices for better outcomes and higher satisfaction levels.
The national flu immunisation programme 2017/18 - training for professionals
1. The national flu immunisation
programme 2017/18
Training for healthcare practitioners
2. Key messages
• flu immunisation is one of the most effective interventions we can provide to reduce
harm from flu and pressures on health and social care services during the winter
• it is important to increase flu vaccine uptake in clinical risk groups because of
increased risk of death and serious illness if people in these groups catch flu
• for a number of years, only around half of patients aged six months to under 65
years in clinical risk groups have been vaccinated
• influenza during pregnancy may be associated with perinatal mortality, prematurity,
smaller neonatal size, lower birth weight and increased risk of complications for
mother
• vaccination of health and social care workers protects them and reduces risk of
spreading flu to their patients, service users, colleagues and family members
• by preventing flu infection through vaccination, secondary bacterial infections such
as pneumonia are prevented. This reduces the need for antibiotics and helps
prevent antibiotic resistance
2 The national flu immunisation programme 2017/18
3. Aims of resource
The purpose of this training resource is to:
• develop the knowledge base of healthcare practitioners regarding the 2017/18
seasonal flu vaccination programme
• support healthcare practitioners involved in discussing flu vaccination with those
eligible by providing evidence based information
• promote high uptake of flu vaccination in those eligible by increasing the knowledge
of those involved in delivering the vaccination programme
• provide information on the administration of flu vaccines
3 The national flu immunisation programme 2017/18
4. Learning outcomes
On completion of this resource, healthcare practitioners will be able to:
• describe the cause of flu
• understand how flu is transmitted and the possible effects of flu
• understand the evidence base for the administration of flu vaccination to those aged 65
years and over and those in clinical risk groups
• explain which vaccines will be used and the precautions and contraindications to the
administration of flu vaccines
• explain the sequence of steps in flu vaccine administration
• explain the possible side effects from flu vaccines
• understand the importance of their role in promoting and providing evidence based
information about flu vaccination to patients
• identify sources of additional information
4 The national flu immunisation programme 2017/18
5. Flu overview
• flu is an acute viral infection of the respiratory tract (nose, mouth, throat,
bronchial tubes and lungs)
• it is a highly infectious illness which spreads rapidly in closed communities
• even people with mild or no symptoms can infect others
• most cases in the UK occur during an 8 to 10 week period during the winter
5
The national flu immunisation programme 2014/15
The national flu immunisation programme 2017/18
6. Influenza viruses
A viruses
• cause outbreaks most years and are the usual cause of epidemics
• live and multiply in wildfowl from where they can be transmitted to humans
• also carried by other mammals
B viruses
• tend to cause less severe disease and smaller outbreaks
• predominantly found in humans
• burden of disease mostly in children
6 The national flu immunisation programme 2017/18
7. FluAvirus
7
The role of haemagglutinin is to bind to the cells of the infected person
The role of neuraminidase is to release the virus from the cell surface
Two surface antigens:
• Haemagglutinin (H) (blue)
• Neuraminidase (N) (red)
Genetic material (RNA) in the centre
There are 18 different types of H and
11 different types of N
The national flu immunisation programme 2017/18
8. Genetic changes in the flu virus – what this means
Changes in the surface antigens (H and N) result in the flu virus constantly changing
• antigenic drift: minor changes (natural mutations) in the genes of flu viruses that
occur gradually over time
• antigenic shift: when two or more different strains combine. This abrupt major change
results in a new subtype. Immunity from previous flu infections/vaccinations may not
protect against the new subtype, potentially leading to a widespread epidemic or
pandemic
Because of the changing nature of flu viruses, WHO monitors their epidemiology
throughout the world. Each year WHO makes recommendations about the strains of
influenza A and B which are predicted to be circulating in the forthcoming winter.
These strains are then included in the flu vaccine developed each year
8 The national flu immunisation programme 2017/18
9. Flu vaccine effectiveness
• efficacy calculated at between 50-60% for adults aged 18 to 65 years
• lower efficacy in elderly although immunisation shown to reduce incidence of
severe disease including bronchopneumonia, hospital admissions and mortality
• in 2014/15 the flu vaccine only provided limited protection against infection as the
main A(H3N2) strain that circulated differed from the A(H3N2) strain selected for
the vaccine
• however, throughout the last decade, there has generally been a good match
between the strains of flu in the vaccine and those that subsequently circulated
9 The national flu immunisation programme 2017/18
10. Features of flu
• easily transmitted by large droplets, small-particle aerosols and by hand to
mouth/eye contamination from a contaminated surface or respiratory
secretions of infected person
• people with mild or no symptoms can still infect others
• incubation period 1-5 days (average 2-3 days) though may be longer
especially in people with immune deficiency
Common symptoms include:
• sudden onset of fever, chills, headache, muscle and joint pain and extreme
fatigue
• dry cough, sore throat and stuffy nose
• in young children gastrointestinal symptoms such as vomiting and diarrhoea
may be seen
10 The national flu immunisation programme 2017/18
11. Possible complications of flu
Common:
• bronchitis
• otitis media (children), sinusitis
• secondary bacterial pneumonia
Less common:
• meningitis, encephalitis, meningoencephalitis
• primary influenza pneumonia
Risk of most serious illness is higher in
• children under six months
• older people
• those with underlying health conditions such as respiratory disease, cardiac
disease, long-term neurological conditions or immunosuppression
• pregnant women (flu during pregnancy may be associated with perinatal mortality,
prematurity, smaller neonatal size and lower birth weight)
11 The national flu immunisation programme 2017/18
12. Flu epidemiology
12
Weekly all age GP influenza-like illness rates for 2016 to
2017 and past seasons, England (RCGP)
• flu activity usually between
September to March (weeks
37 and 15)
• impact of flu varies from
year to year
• moderate levels of influenza
activity seen in 2016/17
season
• biggest impact in older
adults, increased numbers
of care homes outbreaks
and excess mortality seen
particularly in the 65+ year
olds
• high number admissions to
hospital and ICU/HDU
admissions – although
lower than seen in the past
two seasons
The national flu immunisation programme 2017/18
13. UK flu vaccination programme
• Late 1960s: annual flu immunisation recommended to directly protect those in clinical
risk groups who are at a higher risk of influenza associated morbidity and mortality
• 2000: flu vaccine policy extended to include all people aged 65 years or over
• 2010: pregnancy added as a clinical risk category for routine flu immunisation
• 2013: phased introduction of an annual childhood flu vaccination programme for all
children aged 2-16y began with vaccine offered to all children aged 2 and 3 years and
seven geographical pilots in primary school aged children
• 2014: phased introduction of childhood flu vaccination programme continued with
vaccine offered to all children aged 2, 3 and 4 years and geographical pilots in primary
and secondary school aged children
• 2015: offer to all 2, 3 and 4 year old children and children of school years 1 and 2 age
• 2016: offer to all 2, 3 and 4 year old children and children of school years 1, 2 and 3 age
• 2017: offer to all 2 and 3 year old children and children of reception and school years 1,
2, 3 and 4 age (all children who are aged two to eight years old on 31 August 2017 )
13 The national childhood flu immunisation programme 2017/18
14. Flu vaccine eligibility: 2017/18 flu season
• all those aged two and three (but not four years or older) on 31 August 2017 (ie date of
birth on or after 1 September 2013 and on or before 31 August 2015)
• all children in reception class and school years 1, 2, 3 and 4
• all primary school-aged children in former primary school pilot areas
• people aged six months to under 65 years in clinical risk groups
• all pregnant women (including those who become pregnant during flu season)
• people aged 65 years and over (including those becoming 65 years by 31 March 2018)
• people living in long-stay residential care homes or other long-stay care facilities
• carers and household contacts of immunocompromised individuals
Frontline health and social care workers with direct patient/service user contact should be
provided with flu vaccination by their employer. This includes staff in all NHS trusts, general
practices, care homes, and domiciliary care
14 The national flu immunisation programme 2017/18
15. Morbidly obese patients
• JCVI has advised morbidly obese patients (BMI of 40 or above) could benefit from flu
vaccination
• those with morbid obesity (BMI>40) found to be at higher risk of hospitalisation and
death following pandemic influenza infection
• many in this patient group already eligible due to complications of obesity that place
them in another risk category
• in 2017/18, a key change to the flu programme is that vaccination of the morbidly
obese (defined as BMI of 40 and above) will now attract a payment under the
directed enhanced services (DES)
15 The national flu immunisation programme 2017/18
16. Clinical risk groups who should receive flu vaccine (1)
Clinical risk category Examples (this list is not exhaustive and decisions should be based on clinical
judgement)
Chronic respiratory disease Asthma that requires continuous or repeated use of inhaled or systemic steroids or with
previous exacerbations requiring hospital admission.
Chronicobstructivepulmonarydisease(COPD) including chronic bronchitis and
emphysema; bronchiectasis, cystic fibrosis, interstitial lung fibrosis, pneumoconiosis and
bronchopulmonary dysplasia (BPD).
Children who have previously been admitted to hospital for lower respiratory tract
disease.
see precautions section on live attenuated influenza vaccine
Chronic heart disease Congenital heart disease, hypertension with cardiac complications, chronic heart failure,
individuals requiring regular medication and/or follow-up for ischaemic heart disease.
Chronic kidney disease Chronic kidney disease at stage 3, 4 or 5, chronic kidney failure, nephrotic syndrome,
kidney transplantation.
Chronic liver disease Cirrhosis, biliary atresia, chronic hepatitis
Chronic neurological disease
(included in the DES directions for
Wales)
Stroke, transient ischaemic attack (TIA). Conditions in which respiratory function may be
compromised due to neurological disease (eg polio syndrome sufferers).
Clinicians should offer immunisation, based on individual assessment, to clinically
vulnerable individuals including those with cerebral palsy, learning difficulties, multiple
sclerosis and related or similar conditions; or hereditary and degenerative disease of the
nervous system or muscles; or severe neurological disability
Diabetes Type 1 diabetes, type 2 diabetes requiring insulin or oral hypoglycaemic drugs, diet
controlled diabetes.
16 The national flu immunisation programme 2017/18
17. Clinical risk groups who should receive flu vaccine (2)
Clinical risk category Examples (this list is not exhaustive and decisions should be based on
clinical judgement)
Immunosuppression (see
contraindications and
precautions section on live
attenuated influenza
vaccine)
Immunosuppression due to disease or treatment, including patients
undergoing chemotherapy leading to immunosuppression, bone marrow
transplant, HIV infection at all stages, multiple myeloma or genetic
disorders affecting the immune system (eg IRAK-4, NEMO, complement
disorders)
Individuals treated with or likely to be treated with systemic steroids for
more than a month at a dose equivalent to prednisolone at 20mg or more
per day (any age), or for children under 20kg, a dose of 1mg or more per kg
per day.
It is difficult to define at what level of immunosuppression a patient could
be considered to be at a greater risk of the serious consequences of
influenza and should be offered influenza vaccination. This decision is best
made on an individual basis and left to the patient’s clinician.
Some immunocompromised patients may have a suboptimal immunological
response to the vaccine.
Asplenia or dysfunction of the
spleen
This also includes conditions such as homozygous sickle cell disease and
coeliac syndrome that may lead to splenic dysfunction.
Pregnant women Pregnantwomenat anystageofpregnancy(first,secondor third trimesters).
(see precautions section on live attenuated influenza vaccine)
17 The national flu immunisation programme 2017/18
18. Flu immunisation should also be offered to:
• those living in long-stay residential care homes or other long-stay care
facilities where rapid spread is likely to follow introduction of infection and
cause high morbidity and mortality (this does not include prisons, young
offender institutions, university halls of residence etc)
• those who are in receipt of a carer’s allowance, or those who are the main
carer of an elderly or disabled person whose welfare may be at risk if the carer
falls ill
• household contacts of immunocompromised individuals, specifically those
who expect to share living accommodation on most days over the winter and
therefore for whom continuing close contact is unavoidable
• health and social care staff in direct contact with patients/service users
should be vaccinated as part of an employer’s occupational health obligation
18 The national flu immunisation programme 2017/18
19. Other groups who should receive flu vaccine
• the list of clinical risk groups is not exhaustive
• healthcare practitioners should apply clinical judgement to take into account
the risk of flu exacerbating any underlying disease as well as the risk of
serious illness from flu itself
• flu vaccine should be offered to such patients even if the individual is not in
the clinical risk groups specified in the risk groups list
• child contacts of very severely immunocompromised individuals should be
given inactivated vaccine
19 The national flu immunisation programme 2017/18
20. Why vaccinate these risk groups?
Number of fatal flu cases
(%)
Mortality rate per 100,000
population
Age-adjusted relative risk
In a risk group 213 (59.8) 4.0 11.3 (9.1-14.0)
Not in any risk group 143 (40.2) 0.4 Baseline
Chronic renal disease 19 (5.3) 4.8 18.5
Chronic heart disease 32 (9.0) 3.7 10.7 (7.3-15.7)
Chronic respiratory disease 59 (16.6) 2.4 7.4 (5.5-10.0)
Chronic liver disease 32 (9.0) 15.8 48.2 (32.8-70.6)
Diabetes 26 (7.3) 2.2 5.8 (3.8-8.9)
Immunosuppression 71 (19.9) 20.0 47.3 (35.5-63.1)
Chronic neurological disease
(excluding stroke/transient
ischaemic attack)
42 (11.8) 14.7 40.4 (28.7-56.8)
Total 378 0.8
20
Influenza-related population mortality rates and relative risk of death among those aged six months to
under 65 years by clinical risk group in England, September 2010 – May 2011
The national flu immunisation programme 2017/18
21. Vaccination of clinical risk groups
• increasing flu vaccine uptake in clinical risk groups is important because of
increased risk of death and serious illness if people in these groups catch flu
• for a number of years only around half of patients aged six months to under 65 in
clinical risk groups have been vaccinated
• despite those with liver disease and chronic neurological disease having some of
the highest mortality rates, they have low flu vaccine uptake rate compared with
those in other clinical risk groups
• vaccine uptake for all those in clinical risk groups needs to improve - particularly in
those with chronic liver and neurological disease
21 The national flu immunisation programme 2017/18
22. Flu vaccine uptake by age and clinical risk group in
2016/17 (Patientsaged6monthstounder65years)
22 The national flu immunisation programme 2017/18
23. Flu vaccine uptake rates 2015/16 – 2016/17
23 The national flu immunisation programme 2017/18
2016/17 2015/16 Uptake ambition 2017/18
Patients aged 65 years or older 70.5% 71.0% 75%
Patients aged six months to
under 65 years in risk groups
(excluding pregnant women
without other risk factors)
48.6% 45.1%
55%
(maintain higher rates where
this has already been
achieved)
Pregnant women 44.9% 42.3%
55%
(maintain higher rates where
this has already been
achieved)
Health care workers 63.2% 50.6% 75%
Children aged two years old
(including those in risk groups)
38.9% 35.4%
40-65%
(eligible children aged 2 to 8
years)
Children aged three years old
(including those in risk groups)
41.5% 37.7%
Children aged four years old
(including those in risk groups)
33.9% 30.0%
24. Pregnant women
All pregnant women are recommended to receive the inactivated flu vaccine
irrespective of their stage of pregnancy
• pregnant women at increased risk from complications if they contract flu
• having flu during pregnancy may be associated with premature birth and smaller
birth size and weight
• flu vaccination during pregnancy provides passive immunity against flu to infants in
the first few months of life
• studies on safety of flu vaccine in pregnancy show that inactivated flu vaccine can
be safely and effectively administered during any trimester of pregnancy
• no study to date has demonstrated an increased risk of either maternal
complications or adverse fetal outcomes associated with inactivated flu vaccine
• women should be offered the vaccine every time they are pregnant
24 The national flu immunisation programme 2017/18
25. Rationale for vaccinating children against flu
Extension of the seasonal flu vaccination programme to all children aims to
appreciably lower the public health impact of flu by:
•providing direct protection thus preventing a large number of cases of flu
infection in children
•providing indirect protection by lowering flu transmission from children:
• to other children
• to adults
• to those in the clinical risk groups of any age
Reducing flu transmission in the community will avert many cases of severe flu and
flu-related deaths in older adults and people with clinical risk factors
Annual administration of flu vaccine to children is expected to substantially reduce
flu-related illness, GP consultations, hospital admissions and deaths
25 The national flu immunisation programme 2017/18
26. Health and social care workers
• frontline health and social care workers have a duty of care
to protect their patients and service users from infection
• vaccination of health and social care workers protects them
and reduces risk of spreading flu to their patients, service
users, colleagues and family members
• evidence vaccination significantly lowers rates of flu-like
illness, hospitalisation and mortality in the elderly in long-
term healthcare settings
• reduces transmission of flu to vulnerable patients, some of
whom may have impaired immunity and may not respond
well to immunisation
• vaccination of frontline workers also helps reduce sickness
absences and contributes to keeping the NHS and care
services running through winter pressures
26 The national flu immunisation programme 2017/18
27. Health and social care workers (cont)
• NHS and social care bodies have a responsibility to ensure, as far
as is reasonably practicable, that health and social care workers are
free of, and are protected from exposure to infections that can be
caught at work
(Health and Social Care Act 2008, Code of Practice on the prevention and
control of infections)
• responsibility for funding and administering seasonal flu vaccine to
staff lies with employers
• trusts/employers must ensure that health and social care staff
directly involved in delivering care are encouraged to be immunised
and that processes are in place to facilitate this
• overall level of flu vaccine uptake in health care workers is still
below the 75% aspiration
• see NHS Employers flu fighter campaign
www.nhsemployers.org/flu
27 The national flu immunisation programme 2017/18
28. Key messages to health and social care workers
• duty of care as professionals to patients or residents to do everything in your power to
protect them against infection, including being immunised against flu
• getting vaccinated against flu can help protect you, your patients and family
• everyone is susceptible to flu, even if you are in good health and eat well
• you can be infected with the virus and have no symptoms but can still pass flu virus to
others including patients or residents
• good infection control measures reduce spread of flu and other acute respiratory
infections in healthcare settings but are not sufficient alone to prevent them
• impact of flu on frail and vulnerable patients can be fatal and outbreaks can cause
severe disruption in communities, care homes and hospitals
• flu vaccine has a good safety record and will help protect you. It cannot give you flu.
Having the vaccination can encourage your colleagues to do likewise
• throughout the last ten years there has generally been a good to moderate match
between the strains of flu virus in the vaccine and those that subsequently circulated
• staff act as positive role models for patients aged 65 and over, those with long-term
health conditions and pregnant women to take up the offer too
28 The national flu immunisation programme 2017/18
29. When to vaccinate
• those eligible should be given flu vaccination as soon as vaccine is available so
that people are protected when flu begins to circulate in the community
• ideally most vaccination should be completed before the end of December
before flu circulation usually peaks
• flu can circulate considerably later than this however so clinical judgement
should be applied to assess needs of individual patients and whether it is
appropriate to continue to offer vaccination from January to March
• this decision should take into account level of flu-like illness in community and
fact that the immune response following flu vaccination takes about two weeks
to develop fully
• protection afforded by the vaccine thought to last at least one influenza season
• however, as antibody levels likely to reduce in subsequent seasons and there
may be changes to circulating strains from one season to next, annual
revaccination is important
29 The national flu immunisation programme 2017/18
30. 30
Which flu vaccine should
be used?
The national flu immunisation programme 2017/18
31. Types of flu vaccines
Two main types of vaccine available:
• inactivated – by injection
• live attenuated – by nasal application
None of the flu vaccines can cause clinical influenza in those that can be vaccinated
Trivalent: flu vaccines contain two subtypes of Influenza A and one type B virus
Quadrivalent vaccines contain two subtypes of Influenza A and both B virus types*
As quadrivalent vaccines contain both lineages of B viruses and therefore may provide
better protection against the circulating B strain(s) than trivalent flu vaccines, the live
intranasal vaccine offered to children aged 2 years and over is a quadrivalent
vaccine, as is the inactivated vaccine recommended for children aged 3 years and
above who cannot receive live attenuated vaccine
*Quadrivalent inactivated flu vaccine only authorised for children aged 3 years and older.
31 The national flu immunisation programme 2017/18
32. Live attenuated influenza vaccine (LAIV)
• a live attenuated intranasal spray is the recommended vaccine for the childhood flu
programme
• the live attenuated influenza vaccine (LAIV) has been shown to be more effective in
children compared with inactivated influenza vaccines
• it may offer some protection against strains not contained in the vaccine as well as to
those that are and has the potential to offer better protection against virus strains
that have undergone antigenic drift
• since this vaccine is comprised of weakened whole live virus, it replicates natural
infection which induces better immune memory (thereby offering better long-term
protection to children than from the inactivated vaccines)
• in addition to being attenuated (weakened), the live viruses in LAIV have been
adapted to cold so that they cannot replicate efficiently at body temperature
• LAIV has a good safety profile in children aged two years and older
32 The national flu immunisation programme 2017/18
33. Inactivated flu vaccines
• a number of different manufacturers produce flu
vaccines. Those available for 2017/18 season are
listed in ‘The national flu immunisation programme
2017/18’ letter available on PHE website
• most of the inactivated vaccines are administered
by intramuscular injection, although one vaccine
(Intanza®) is administered by the intradermal
route
• all currently available flu vaccines are prepared
from viruses grown in embryonated hens’ eggs –
details of ovalbumin content available in the
product SPC
• some flu vaccines are restricted for use in
particular age groups. The SPC for individual
products should always be referred to when
ordering vaccines for particular patients
33 The national flu immunisation programme 2017/18
34. Storage of flu vaccine
Efficacy, safety and quality may be adversely affected if vaccines are not
stored at the temperatures specified in the licence
Flu vaccines must be stored in accordance with manufacturer’s instructions:
• store between +2⁰C and +8⁰C
• do not freeze
• store in original packaging
• protect from light
Check expiry dates regularly:
• the LAIV has an expiry date 18 weeks after manufacture – this is much shorter
than inactivated flu vaccines
• it is important that the expiry date on the nasal spray applicator is checked
before use
34 The national flu immunisation programme 2017/18
35. Flu vaccines for patients in clinical risk groups
Age Which vaccine? How many doses?
Children aged six
months to less than
two years of age in
clinical risk groups
These children should be offered inactivated trivalent
influenza vaccine
Those who have not received flu
vaccine before should receive a
second dose of vaccine at least four
weeks later
Children aged two to
less than 18 years of
age in clinical risk
groups
These children should be offered the live intranasal vaccine
unless it is medically contraindicated
For those children for whom the live vaccine is medically
contraindicated, a suitable inactivated flu vaccine should be
offered
The quadrivalent inactivated influenza vaccine (Fluarix™
Tetra) is authorised for children from the age of three years
and is preferred because of the additional protection
offered. The quadrivalent vaccine has both lineages of
influenza B and may therefore provide better protection
against the circulating B strain(s) than trivalent inactivated
influenza vaccines
Children aged two years should be given an inactivated
trivalent vaccine
Those aged two to less than nine
years who have not received flu
vaccine before should receive a
second dose of vaccine at least four
weeks later
Over 18 years Any of the inactivated vaccines (except Intanza®15μg
which is for those age 60 years and over)
A single dose
35 The national flu immunisation programme 2017/18
36. Which vaccine and how many doses?
Vaccine type Authorised age indication Dose
Live attenuated intranasal
vaccine
Children aged two to under 18
years (if no contraindications)
Singleapplicationineach nostril of 0.1ml
Children NOT in clinical risk groups only
require one dose of this vaccine.
Childrenin clinicalrisk groups aged two to
under nine years who have not received
influenza vaccine before should receive a
second dose of vaccine at least four weeks
later.
N.B Follow Green Book not SPC
Inactivated intramuscular
vaccine (number of different
brands)
Children aged six months and
older and adults
(N.B some of the vaccines are
not authorised for young
children)
Single injection of 0.5ml
Children aged six months to under nine
years who have not received influenza
vaccine before should receive a second
dose of vaccine at least four weeks later.
Inactivated intradermal
vaccine - Intanza® 15µg
Adults aged 60 years and older Single injection of 0.1ml
36 The national flu immunisation programme 2017/18
37. Trivalent vaccines will contain the following three viruses:
• an A/Michigan/45/2015 (H1N1)pdm09-like virus
• an A/Hong Kong/4801/2014 (H3N2)-like virus
• a B/Brisbane/60/2008-like virus
In addition to the above, the quadrivalent vaccine will also contain:
B/Phuket/3073/2013-like virus
None of the influenza vaccines for the 2017/18 season contain thiomersal as an
added preservative
More detailed information on the characteristics of the available vaccines, including
age indications can be found in the Influenza chapter of the Green Book
(Immunisation against infectious disease) and the product SPCs
37
Flu vaccine composition 2017/18
The national flu immunisation programme 2017/18
38. Flu vaccine presentation and dosage
38
• inactivated flu vaccines for intramuscular (IM) administration supplied as
suspensions in pre-filled syringes containing a 0.5ml dose
• if SPC for IM inactivated flu vaccine states young children can be given
either a 0.25ml or a 0.5ml dose, give 0.5ml dose
• Intanza®, the intradermal vaccine, is supplied in a micro-needle injection
system (but not available in 2017/18 flu season)
• the live intranasal flu vaccine is supplied as a nasal spray suspension in a
special single use, pre-filled, nasal applicator. No reconstitution or dilution
required. Each applicator contains 0.2ml (administered as 0.1 ml per
nostril)
The national flu immunisation programme 2017/18
39. Vaccine administration (inactivated vaccines)
Intramuscular flu vaccines should be given into the upper arm (or anterolateral thigh in
infants under one year of age)
Individuals with a bleeding disorder should be given vaccine by deep subcutaneous injection
to reduce the risk of bleeding
Intradermal: Intanza® is supplied in a micro-needle injection system that should be held at
right-angles to the skin. The device allows intradermal vaccination to be performed without
the need for additional training
• both inactivated and live flu vaccines can be given at the same time as, or at any
interval before or after, other live and inactivated vaccines
• different vaccines should be given at separate sites, preferably in a different limb. If
given in the same limb, they should be given at least 2.5cm apart
39 The national flu immunisation programme 2017/18
40. Administration of LiveAttenuated Influenza
vaccine (LAIV)
• LAIV is different from other flu vaccines – it is a live attenuated nasal
vaccine and must not be injected
• do not attempt to attach a needle
• LAIV can be administered at the same time as, or at any interval from
other vaccines including live vaccines
• patient should breathe normally – no need to actively inhale or sniff
• the vaccine is rapidly absorbed so no need to repeat either half of dose if
patient sneezes, blows their nose or their nose drips following
administration
40 The national flu immunisation programme 2017/18
41. 41
Supply and administration of flu vaccines
A range of mechanisms can be used for the supply and administration of vaccines,
including:
• patient specific prescription written manually or electronically by a registered
medical practitioner or other authorised prescriber
• Patient Specific Direction (PSD)
• Patient Group Direction (PGD)
PGD templates for the administration of the live and inactivated flu vaccines are
available on the PHE website:
https://www.gov.uk/government/collections/immunisation-patient-group-direction-pgd
Those using national immunisation PGDs developed by PHE must ensure that each
PGD is organisationally authorised and signed in section 2 by an appropriate authorising
person, in accordance with Human Medicines Regulations 2012 (HMR2012)
Without such authorisation, the PGD is not legal or valid
The national flu immunisation programme 2017/18
42. There are very few individuals who cannot receive any flu vaccine
Where there is doubt, expert advice should be sought promptly so that the period the
individual is left unvaccinated is minimised
For children aged 2 years up to their 18th birthday, where live flu vaccine cannot be
given, it is likely that inactivated vaccine could be given instead
None of the influenza vaccines should be given to those who have had:
• confirmed anaphylactic reaction to a previous dose of the vaccine
• confirmed anaphylactic reaction to any component of the vaccine
42 The national flu immunisation programme 2017/18
Contraindications
43. The live attenuated flu vaccine should not be given to children who are:
• clinically severely immunodeficient due to conditions or immunosuppressive therapy:
acute and chronic leukaemias
lymphoma
HIV infection not on highly active antiretroviral therapy
cellular immune deficiencies
high dose corticosteroids
• receiving salicylate therapy
• known to be pregnant
• have severe asthma or active wheezing
• children currently taking a high dose inhaled steroid should only be given live flu vaccine
on the advice of their specialist
The national flu immunisation programme 2014/15
Contraindications to flu vaccines (cont)
43 The national flu immunisation programme 2017/18
44. Acutely unwell:
• defer until recovered
Heavy nasal congestion:
• defer live intranasal vaccine until resolved or, if the child is in a risk group,
consider inactivated flu vaccine to provide protection without delay
Use with antiviral agents against flu:
• live flu vaccine (LAIV) should not be administered at the same time or within 48
hours of cessation of treatment with flu antiviral agents
• administration of flu antiviral agents within two weeks of administration of LAIV
may adversely affect the effectiveness of the vaccine
44 The national flu immunisation programme 2017/18
Precautions to flu vaccines
45. Severe asthma or active wheezing
• live flu vaccine is not recommended for children and adolescents with
severe asthma or active wheezing eg those who are currently taking or have
been prescribed oral steroids for respiratory disease in the last 14 days
• children currently taking a high dose inhaled steroid - Budesonide
>800mcg/day or equivalent (eg Fluticasone > 500mcg/day) should only be
given live flu vaccine on the advice of their specialist
As these children are in a defined flu risk group, those who cannot receive
LAIV should receive an inactivated flu vaccine
• vaccination with LAIV should be deferred in children with a history of active
wheezing in the past 72 hours or those who have increased use of
bronchodilators in the previous 72 hours. If condition not improved after a
further 72 hours then inactivated flu vaccine should be offered to avoid
delaying protection in this high-risk group
45 The national flu immunisation programme 2017/18
46. Egg allergy – adults
• most flu vaccines are prepared from flu viruses grown in embryonated
hens’ eggs – the final vaccine products contains varying amounts of egg
(as ovalbumin)
• adults with egg allergy can be immunised in any setting using an
inactivated flu vaccine with an ovalbumin content less than 0.12
µg/ml (equivalent to <0.06µg for 0.5ml dose)
• adults with severe anaphylaxis to egg that has previously required
intensive care should be referred to specialists for immunisation in
hospital
• there is no ovalbumin-free vaccine available for the 2017/18 flu season
• see July 2017 edition ‘Vaccine Update’ or individual vaccine SPCs for
ovalbumin content
46 The national flu immunisation programme 2017/18
47. Egg allergy – children
• children with an egg allergy can be safely vaccinated with the LAIV in any
setting (including primary care and schools)
• those with both egg allergy and clinical risk factors that contraindicate LAIV
(eg immunosuppression) should be offered an* inactivated flu vaccine with
a very low ovalbumin content (less than 0.12μg/ml)
• children with a history of severe anaphylaxis to egg that has previously
required intensive care, should be referred to specialists for immunisation
in hospital
• LAIV is not otherwise contraindicated in children with egg allergy. Egg-
allergic children with asthma can receive LAIV if their asthma is well-
controlled (see previous slide on severe asthma)
*Children in a clinical risk group and aged under nine years who have not been previously
vaccinated against influenza will require a second dose whether given LAIV or inactivated
vaccine
47 The national flu immunisation programme 2017/18
48. Flu vaccines with low ovalbumin content
The following vaccines, available for the 2017/18 flu season, have a very low ovalbumin
content (<0.12μg/ml – equivalent to <0.06μg for a 0.5ml dose) and may be used safely in
individuals with egg allergy
LAIV (Fluenz Tetra®), which has ovalbumin content of ≤0.12 (≤0.024/0.2ml dose)has also been shown to
be safe for use in most egg allergic children
48 The national flu immunisation programme 2017/18
Supplier Name of product Vaccine type Age
indication
Ovalbumin content
per dose ( μg/dose)
AstraZeneca
UK Ltd
Fluenz Tetra Live attenuated, nasal
(quadrivalent)
From 24
months to
less than 18
years of age
≤0.12
(≤0.024/0.2ml dose)
GSK Fluarix Tetra Split virion inactivated virus From three
years
≤0.1 (≤0.05/0.5ml dose)
MASTA Inactivated Influenza
Vaccine (Split Virion)
BP
Split virion inactivated virus From six
months
≤0.1 (≤0.05/0.5ml dose)
MASTA
Quadrivalent Influenza
Vaccine (Split Virion,
inactivated)
Split virion inactivated virus
From three
years ≤0.1 (≤0.05/0.5ml dose)
Sanofi
Pasteur
Vaccines
Inactivated influenza
vaccine (split virion) BP
Split virion inactivated virus From six
months
≤0.1 (≤0.05/0.5ml dose)
Sanofi
Pasteur
Vaccines
Quadrivalent Influenza
Vaccine (Split Virion,
inactivated)
Split virion inactivated virus From 3 years ≤0.1 (≤0.05/0.5ml dose)
See Vaccine Update July 2017 for list of all flu vaccines and their ovalbumin content
49. • theoretical potential for transmission of live attenuated virus to
immunocompromised contacts
• risk is for one to two weeks following vaccination
• extensive use of the live attenuated influenza vaccine in US – no reported
instances of illness or infections from the vaccine virus among
immunocompromised patients inadvertently exposed to vaccinated children
• however, where close contact with very severely immunocompromised
patients (eg bone marrow transplant patients requiring isolation) is likely or
unavoidable (eg household members) consider an appropriate inactivated
flu vaccine instead
49 The national flu immunisation programme 2017/18
Risk of transmission of live vaccine virus
50. Exposure of healthcare workers to live attenuated
influenza vaccine viruses
• theoretically there may be some low level exposure to the vaccine viruses for those
administering LAIV and/or from recently vaccinated patients
• in the US, where there has been extensive use of LAIV, no reported instances of illness
or infections from the vaccine virus among healthcare workers inadvertently exposed
• risk of acquiring vaccine viruses from the environment is unknown but probably low
• the vaccine viruses are cold-adapted and attenuated and therefore unlikely to cause
symptomatic influenza
• as a precaution, very severely immunosuppressed individuals should not
administer LAIV
• other healthcare workers who have less severe immunosuppression or are pregnant,
should follow normal clinical practice to avoid inhaling the vaccine and ensure that they
themselves are appropriately vaccinated
50 The national flu immunisation programme 2017/18
51. Inadvertent administration of LAIV
• if an immunocompromised individual receives LAIV, the degree of
immunosuppression should be assessed
• if patient is severely immunocompromised, antiviral prophylaxis should be considered
• otherwise they should be advised to seek medical advice if they develop flu-like
symptoms in the four days following administration of the vaccine
• if antivirals are used for prophylaxis or treatment, patient should also be offered
inactivated flu vaccine in order to maximise their protection in the forthcoming flu
season (this can be given straight away)
51 The national flu immunisation programme 2017/18
52. Commonly reported adverse reactions
Following inactivated flu vaccine:
• pain, swelling or redness at the injection site, low grade fever, malaise, shivering,
fatigue, headache, myalgia and arthralgia
• a small painless nodule may also form at the injection site
• these symptoms usually disappear within one to two days without treatment
Following live attenuated flu vaccine:
• nasal congestion/rhinorrhoea, reduced appetite, weakness and headache
Rarely, after live or inactivated vaccine, immediate reactions such as urticaria, angio-
oedema, bronchospasm and anaphylaxis can occur
52 The national flu immunisation programme 2017/18
53. 53 The national flu immunisation programme 2017/18
Reporting suspected adverse reactions
All serious suspected reactions following flu
vaccination should be reported to the Medicines
and Healthcare products Regulatory Agency
using the Yellow Card scheme at
http://yellowcard.mhra.gov.uk/
All of the quadrivalent flu vaccines carry a black
triangle symbol (▼) (as do all vaccines during
the earlier stages of their introduction)
This is to encourage reporting of all suspected
adverse reactions
54. Vaccine ordering
• all flu vaccines for children (both live and inactivated) are purchased centrally by
PHE for:
• all children aged 2 and 3 years and children in reception class and school
years 1 to 4
• all children in clinical risk groups aged 6 months to less than 18 years
• PHE will supply LAIV for those children who can receive it and inactivated flu vaccine
for those children for whom LAIV is contraindicated.
• flu vaccines for children can be ordered through the ImmForm website as for other
centrally purchased vaccines (www.immform.dh.gov.uk)
• providers are responsible for ordering sufficient flu vaccine for all other eligible
patients aged 18 years and older directly from manufacturers
• ordering from more than one supplier is recommended in case of supplier delays or
difficulties in the manufacture or delivery of the vaccine
54 The national flu immunisation programme 2017/18
55. Inactivated influenza vaccine for children
contraindicated to receive LAIV
• children for whom LAIV is contraindicated should be offered a suitable alternative
inactivated flu vaccine
• some inactivated flu vaccines have been associated with high rates of febrile convulsions
in children
• some inactivated flu vaccines contain too much ovalbumin for egg allergic children
• check SPC for vaccine suitability before administration
Guidance on which vaccines to use for those children who cannot receive LAIV can be
found in the Green Book Influenza chapter
• Fluarix Tetra® is the preferred vaccine for children aged ≥ 3years who cannot receive
Fluenz Tetra®
• children 6m to <3years should be given inactivated influenza vaccine (Split Virion) BP®
55 The national flu immunisation programme 2017/18
56. Beware of product confusion!
Fluenz Tetra® is the live attenuated influenza vaccine given as a nasal spray to
children aged 2 years to less than 18 years
Fluarix® Tetra is an inactivated vaccine licensed from three years of age that
can be given to children who cannot receive the live intranasal flu vaccine, the
65year olds and overs, the under 65 year oldss at risk, pregnant women and
healthcare workers
Care must be taken not to confuse the two ‘Tetra’ brands.
One way of remembering which vaccine is which is:
• Fluenz is the nazal flu vaccine
• Fluarix is the arm injected vaccine
56 The national flu immunisation programme 2017/18
57. Recording of flu vaccine given
As a wide variety of influenza vaccines are on the UK market each year, it is especially
important that the following information be recorded:
• vaccine name, product name, batch number and expiry date
• dose administered
• date immunisation given
• route/site used
• name and signature of vaccinator
This information should be recorded in:
• patient's GP record (or other patient record, depending on location)
• personal Child Health Record (the ‘Red Book’) if a child
• practice computer system
• Child Health Information System if a child
57 The national flu immunisation programme 2017/18
58. Data collection
• flu vaccine uptake data is collected via the web-based ImmForm system
(www.immform.dh.gov.uk) where it is managed and published by PHE
• over 90% GP practices are able to make automated data returns where the
number of their patients vaccinated is directly extracted from their IT system
and put into ImmForm
• for data to be accurate and complete, it is critical that vaccines given outside
the surgery, eg in antenatal clinics or pharmacies, are reported to the
patient’s GP
• uptake data for Reception class, school years 1 to 4 and pilot areas will be
manually submitted by providers onto ImmForm
• uptake data for HCWs is manually submitted by trusts and area teams via
ImmForm
• data is collected and published monthly on all the groups for whom flu
vaccine is indicated at national level and local NHS England team level to
enable performance to be reviewed and time to take action if needed
58 The national flu immunisation programme 2017/18
59. Achieving high uptake (GP Practice checklist)
In order to obtain high vaccine uptake, it is recommended that GP practices:
1. Identify a named lead individual within the practice who is responsible for the
flu vaccination programme and liaises regularly with all staff involved in the
programme
2. Hold a register that can identify all pregnant women and patients in the under
65 years at risk groups, those aged 65 years and over, and those aged two to
three years
3. Update the patient register throughout the flu season, paying particular
attention to the inclusion of women who become pregnant and patients who
enter at-risk groups during the flu season
4. Submit accurate data on the number of its patients eligible to receive flu
vaccine and the flu vaccinations given to its patients on ImmForm
(www.immform.dh.gov.uk), ideally using the automated function. Submit data
on uptake among healthcare workers in primary care using the ImmForm data
collection tool
59 The national flu immunisation programme 2017/18
60. Achieving high uptake (GPPractice checklist cont’d)
5. Order sufficient flu vaccine taking into account past and planned improved
performance, expected demographic increase, and to ensure that everyone at
risk is offered the flu vaccine. It is recommended that vaccine is ordered from
more than one supplier and in respect of children, from PHE central supplies
through the ImmForm website
6. Invite patients recommended to receive the flu vaccine to a flu vaccination
clinic or to make an appointment (eg by letter, email, phone call, text). This is a
requirement of the enhanced service specification
7. Follow-up patients, especially those in at risk groups, who do not respond or
fail to attend scheduled clinics or appointments
8. Start flu vaccination as soon as practicable after receipt of the vaccine. This will
help ensure the maximum number of patients are vaccinated as early as
possible and protected before flu starts to circulate. Aim to complete
immunisation of all eligible patients before flu starts to circulate and ideally by
end of December
60 The national flu immunisation programme 2017/18
61. Achieving high uptake (GPPractice checklist cont’d )
9. Collaborate with maternity services to offer and provide flu vaccination to pregnant
women and to identify, offer and provide to newly pregnant women as the flu season
progresses
10. Offer flu vaccination in clinics and opportunistically
11. Where the patient has indicated they wish to receive the vaccination but is physically
unable to attend the practice (eg is housebound) the practice must make all reasonable
effort to ensure the patient is vaccinated. The GP practice and/or CCG will collaborate
with other providers such as community pharmacies and community or health and social
care trusts to identify and offer flu vaccination to residents in care homes, nursing
homes and house-bound patients, and to ensure that mechanisms are in place to
update the patient record when flu vaccinations are given by other providers
The GP practice checklist highlights good practice
• it is based upon the findings from a study examining the factors associated with higher
vaccine uptake in general practice
• GP practices are encouraged to review their systems in the light of the checklist
Most recommendations will apply to other settings where flu vaccine is given
61 The national flu immunisation programme 2017/18
63. Key messages
• flu immunisation is one of the most effective interventions we can provide to
reduce harm from flu and pressures on health and social care services during
the winter
• it is important to increase flu vaccine uptake in clinical risk groups because of
increased risk of death and serious illness if people in these groups catch flu
• for a number of years, only around half of patients aged six months to under 65
years in clinical risk groups have been vaccinated
• influenza during pregnancy may be associated with perinatal mortality,
prematurity, smaller neonatal size, lower birth weight and increased risk of
complications for mother
• vaccination of health and social care workers protects them and reduces risk of
spreading flu to their patients, service users, colleagues and family members
• by preventing flu infection through vaccination, secondary bacterial infections
such as pneumonia are prevented. This reduces the need for antibiotics and
helps prevent antibiotic resistance
63 The national flu immunisation programme 2017/18
64. 64 The national flu immunisation programme 2017/18
Resources
• Flu Plan and Letter detailing 2017/18 flu programme
Department of Health, Public Health England, NHS England. Published 20 March 2017 Available at:
https://www.gov.uk/government/publications/national-flu-immunisation-programme-plan
• Green Book Influenza chapter Available at:
https://www.gov.uk/government/collections/immunisation-against-infectious-disease-the-green-book
• Leaflets, posters, information materials and other resources to support the annual flu
programme Available at: https://www.gov.uk/government/collections/annual-flu-programme
• PGD templates for flu vaccines https://www.gov.uk/government/collections/immunisation-patient-
group-direction-pgd
• A video for health professionals on how to administer the LAIV vaccine produced by NHS
Education for Scotland is available at http://www.nes.scot.nhs.uk/education-and-training/by-
theme-initiative/public-health/health-protection/seasonal-flu/childhood-seasonal-flu-
vaccination-programme-resources-for-registered-practitioners.aspx
• Summary of Product Characteristics (SPC) for flu vaccines are available at
http://www.medicines.org.uk/emc/
• Find out more about antibiotic resistance, other ways to reduce its rise and how you can help
through www.antibioticguardian.com