This study examined factors that influence job satisfaction among secondary school teachers in Sindh, Pakistan. A survey was administered to 305 teachers to assess the impact of work-life balance, administrative support, salary, and teacher input in decision making on job performance and satisfaction. The findings showed strong correlations between work-life balance and administrative support with job satisfaction, but not salary or teacher input. No significant differences were found between male and female teachers. The study recommends improving work-life balance support and involving teachers more in decision making to boost job satisfaction.