Target selection lead discovery medicinal drug discovery strategy style design 5 powerpoint presentation templates.

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The document outlines the multi-step drug discovery process, including cellular and genetic target identification, compound synthesis and isolation, library development, drug affinity and selectivity testing, animal disease modeling, and clinical trials. Key steps involve genomics, proteomics, high-throughput screening, medicinal chemistry, in vitro and in vivo studies to identify lead candidates and refine drug properties before progressing to clinical testing.

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The document outlines the key stages of the drug discovery process, including identifying genetic and cellular targets, synthesizing and isolating compounds through combinatorial chemistry and high-throughput screening, developing structure-activity relationships through in silico and in vitro studies, evaluating drug affinity and selectivity in cellular and disease models, testing lead candidates in animal models of disease states, and conducting clinical trials and therapeutics in humans.

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The document outlines the key stages in the drug discovery process, including target selection, lead discovery, drug development, preclinical testing, and clinical trials. Genetic and cellular targets are identified through genomics and proteomics. Combinatorial chemistry and high-throughput screening are used to develop compound libraries and identify potential drug candidates. Lead compounds are refined through medicinal chemistry and testing in cellular and animal disease models. Top candidates then progress to clinical trials in humans to test for safety and efficacy.

Traditional drug discovery process design 6 powerpoint ppt slides.

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The document describes two approaches to drug discovery: the traditional approach and the SWITCH drug re-profiling approach. The traditional approach involves lengthy timelines of 0.5-6 years across target identification, validation, lead identification, candidate optimization, pre-clinical trials, and clinical trials. The SWITCH approach aims to shorten timelines by mining existing drug data to identify new therapeutic uses for existing drugs and performing a clinical proof of concept trial within 0.5-1 year on a re-profiled drug.

Drug discovery process style 6 powerpoint presentation templates

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The document describes two approaches to drug discovery: traditional drug discovery and a SWITCH drug re-profiling approach. The traditional approach involves multiple sequential steps over 6-10 years, including target identification, validation, lead identification, candidate optimization, pre-clinical testing, and clinical trials. The SWITCH approach uses data mining to identify existing drugs that could be re-purposed for new indications, potentially shortening the process to just 0.5-1 years for target identification and proof-of-concept clinical trials on re-profiled drugs.

Drug discovery process style 5 powerpoint presentation templates

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The document describes the key stages in the drug discovery process, including cellular and genetic target identification, compound synthesis and isolation, high-throughput screening, lead optimization, preclinical testing in animal models and in vitro/in vivo studies, and clinical trials in humans. The flow diagram shows the iterative process moving from early research to identify biological targets through compound development and testing, culminating in clinical evaluation and potential approval of new therapeutics.

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The document outlines the key steps in the drug discovery process: 1. Identification of target molecules through genomic research and functional analysis of genes and enzymes. 2. Discovery of seed lead compounds through high-throughput screening and combinatorial chemistry. 3. Scrutiny of drug candidates including estimation of drug efficacy and safety evaluation. 4. Manufacturing development and clinical studies prior to new drug application and launch.

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Target selection lead discovery medicinal drug discovery strategy style design 5 powerpoint presentation templates.

1. Drug Discovery Process - Style 5 Cellular & Synthesis & Library Drug Affinity Animal Models Clinical Trials Genetic Targets Isolation Development & Selectivity of Disease States & Therapeutics Combinatorial Structure Activity Cellular Behavioural Genomics Disease Models Studies Chemistry Studies Assay In Silico Mechanism Functional Proteomics Development Screening of Action Imaging Bioinformatics High-throughput Chemical Lead Candidate Ex Vivo Screening Synthesis Refinement Studies Target Lead Medicinal In Vitro In Vivo Selection Discovery Chemistry Studies Studies www.slideteam.net Your logo

2. Drug Discovery Process - Style 5 Cellular & Synthesis & Library Drug Affinity Animal Models Clinical Trials Genetic Targets Isolation Development & Selectivity of Disease States & Therapeutics Combinatorial Structure Activity Cellular Behavioural Genomics Disease Models Studies Chemistry Studies Assay In Silico Mechanism Functional Proteomics Development Screening of Action Imaging Bioinformatics High-throughput Chemical Lead Candidate Ex Vivo Screening Synthesis Refinement Studies Target Lead Medicinal In Vitro In Vivo Selection Discovery Chemistry Studies Studies Text Here Text Here Text Here Text Here Text Here Text Here • Your Text • Your Text • Your Text • Your Text • Your Text • Your Text Goes here Goes here Goes here Goes here Goes here Goes here • Download • Download • Download • Download • Download • Download this this this this this this awesome awesome awesome awesome awesome awesome diagram diagram diagram diagram diagram diagram www.slideteam.net Your logo

3. Drug Discovery Process - Style 5 Cellular & Synthesis & Library Drug Affinity Animal Models Clinical Trials Genetic Targets Isolation Development & Selectivity of Disease States & Therapeutics Combinatorial Structure Activity Cellular Behavioural Genomics Disease Models Studies Chemistry Studies Assay In Silico Mechanism Functional Proteomics Development Screening of Action Imaging Bioinformatics High-throughput Chemical Lead Candidate Ex Vivo Screening Synthesis Refinement Studies Target Lead Medicinal In Vitro In Vivo Selection Discovery Chemistry Studies Studies Text Here Text Here Text Here Text Here Text Here Text Here • Your Text • Your Text • Your Text • Your Text • Your Text • Your Text Goes here Goes here Goes here Goes here Goes here Goes here • Download • Download • Download • Download • Download • Download this this this this this this awesome awesome awesome awesome awesome awesome diagram diagram diagram diagram diagram diagram www.slideteam.net Your logo

4. Drug Discovery Process - Style 5 Cellular & Synthesis & Library Drug Affinity Animal Models Clinical Trials Genetic Targets Isolation Development & Selectivity of Disease States & Therapeutics Combinatorial Structure Activity Cellular Behavioural Genomics Disease Models Studies Chemistry Studies Assay In Silico Mechanism Functional Proteomics Development Screening of Action Imaging Bioinformatics High-throughput Chemical Lead Candidate Ex Vivo Screening Synthesis Refinement Studies Target Lead Medicinal In Vitro In Vivo Selection Discovery Chemistry Studies Studies Text Here Text Here Text Here Text Here Text Here Text Here • Your Text • Your Text • Your Text • Your Text • Your Text • Your Text Goes here Goes here Goes here Goes here Goes here Goes here • Download • Download • Download • Download • Download • Download this this this this this this awesome awesome awesome awesome awesome awesome diagram diagram diagram diagram diagram diagram www.slideteam.net Your logo

5. Drug Discovery Process - Style 5 Cellular & Synthesis & Library Drug Affinity Animal Models Clinical Trials Genetic Targets Isolation Development & Selectivity of Disease States & Therapeutics Combinatorial Structure Activity Cellular Behavioural Genomics Disease Models Studies Chemistry Studies Assay In Silico Mechanism Functional Proteomics Development Screening of Action Imaging Bioinformatics High-throughput Chemical Lead Candidate Ex Vivo Screening Synthesis Refinement Studies Target Lead Medicinal In Vitro In Vivo Selection Discovery Chemistry Studies Studies Text Here Text Here Text Here Text Here Text Here Text Here • Your Text • Your Text • Your Text • Your Text • Your Text • Your Text Goes here Goes here Goes here Goes here Goes here Goes here • Download • Download • Download • Download • Download • Download this this this this this this awesome awesome awesome awesome awesome awesome diagram diagram diagram diagram diagram diagram www.slideteam.net Your logo

6. Drug Discovery Process - Style 5 Cellular & Synthesis & Library Drug Affinity Animal Models Clinical Trials Genetic Targets Isolation Development & Selectivity of Disease States & Therapeutics Combinatorial Structure Activity Cellular Behavioural Genomics Disease Models Studies Chemistry Studies Assay In Silico Mechanism Functional Proteomics Development Screening of Action Imaging Bioinformatics High-throughput Chemical Lead Candidate Ex Vivo Screening Synthesis Refinement Studies Target Lead Medicinal In Vitro In Vivo Selection Discovery Chemistry Studies Studies Text Here Text Here Text Here Text Here Text Here Text Here • Your Text • Your Text • Your Text • Your Text • Your Text • Your Text Goes here Goes here Goes here Goes here Goes here Goes here • Download • Download • Download • Download • Download • Download this this this this this this awesome awesome awesome awesome awesome awesome diagram diagram diagram diagram diagram diagram www.slideteam.net Your logo

7. Drug Discovery Process - Style 5 Cellular & Synthesis & Library Drug Affinity Animal Models Clinical Trials Genetic Targets Isolation Development & Selectivity of Disease States & Therapeutics Combinatorial Structure Activity Cellular Behavioural Genomics Disease Models Studies Chemistry Studies Assay In Silico Mechanism Functional Proteomics Development Screening of Action Imaging Bioinformatics High-throughput Chemical Lead Candidate Ex Vivo Screening Synthesis Refinement Studies Target Lead Medicinal In Vitro In Vivo Selection Discovery Chemistry Studies Studies Text Here Text Here Text Here Text Here Text Here Text Here • Your Text • Your Text • Your Text • Your Text • Your Text • Your Text Goes here Goes here Goes here Goes here Goes here Goes here • Download • Download • Download • Download • Download • Download this this this this this this awesome awesome awesome awesome awesome awesome diagram diagram diagram diagram diagram diagram www.slideteam.net Your logo

8. Drug Discovery Process - Style 5 Cellular & Synthesis & Library Drug Affinity Animal Models Clinical Trials Genetic Targets Isolation Development & Selectivity of Disease States & Therapeutics Combinatorial Structure Activity Cellular Behavioural Genomics Disease Models Studies Chemistry Studies Assay In Silico Mechanism Functional Proteomics Development Screening of Action Imaging Bioinformatics High-throughput Chemical Lead Candidate Ex Vivo Screening Synthesis Refinement Studies Target Lead Medicinal In Vitro In Vivo Selection Discovery Chemistry Studies Studies Text Here Text Here Text Here Text Here Text Here Text Here • Your Text • Your Text • Your Text • Your Text • Your Text • Your Text Goes here Goes here Goes here Goes here Goes here Goes here • Download • Download • Download • Download • Download • Download this this this this this this awesome awesome awesome awesome awesome awesome diagram diagram diagram diagram diagram diagram www.slideteam.net Your logo

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