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TAKING MEDICATIONS Why take pills? How do oral medications work? Diabetes is a progressive condition. Depending on what type a person has, their healthcare team will be able to determine which medications they should be taking and help them understand how your medications work. They can demonstrate the effective drug therapy in combination with healthy lifestyle choices, can lower blood glucose levels, reduce the risk for diabetes complications and produce other clinical benefits. The goal is for the patient to be knowledgeable about all medications, including its action, side effects, efficacy, toxicity, prescribed dosage, appropriate timing and frequency of administration, effect of missed and delayed doses and instructions for storage, travel and safety.
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Diabetes Mellitus (DM) is a metabolic disorder of which inappropriate hyperglycemia is the hallmark. For this reason, several classes of oral hypoglycemic drugs like Sulfonylurea, Biguanides, Meglitinides, Thiazolidinediones, α-glucosidase inhibitors are prescribed to treat Diabetes Mellitus. But at present Dipeptidyl Peptidase (DPP-4) Inhibitors have attracted attention as oral hypoglycemic agents that recently introduced to Bangladesh. This study aims to evaluate the current prescribing pattern of DPP-4 inhibitors at BIRDEM hospital, Bangldesh.during the survey, 150 prescriptions were collected and investigated where only 49% DPP-4 inhibitors – Sitagliptin, Linagliptin, Vildagliptin are prescribed even along with other conventional oral hypoglycemic drug. According to this survey, it is clear that Dipetidyl Peptidase (DPP-4) inhibitors is becoming more popular day by day in the management of hyperglycemia in Type-2 Diabetes without causing weight gain or hypoglycaemia in Bangladesh.
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Nutrease powder- A natural plant based nutritional shake helps to supports in...
Supplementation of Nutrease powder is essential for proactive prevention and also for the best outcome therapy in Diabetes.
Supplementing essential and conditionally essential nutrients like Nutrease powder to support essential metabolic pathways
is required for immune defense and repair, neuro-hormone balance as well as digestive and detox competencies.
Impaired antioxidant status has been shown to have a definite role in the development of insulin resistance and type 2
diabetes. Overproduction of oxidants (reactive oxygen species and reactive nitrogen species) in the human body is
responsible for the pathogenesis of some diseases. The scavenging of these oxidants is thought to be an effective measure to
depress the level of oxidative stress of organisms. It has been reported that intake of Nutrease powder is inversely associated
with the risk of many chronic diseases, and antioxidant phytochemicals in Nutrease powder are considered to be responsible
for these health benefits. Antioxidant phytochemicals found in Nutrease powder plays an important role in the prevention
and treatment of chronic diseases caused by oxidative stress. They often possess strong antioxidant and free radical
scavenging abilities, which are also the basis of other bioactivities and health benefits, such as diabetes mellitus.
Phytonutrients in Nutrease powder play a positive role by maintaining and modulating immune function to prevent specific
diseases. Being natural products, they hold a great promise in clinical therapy. Phytonutrients are the plant nutrients with
specific biological activities that support human health. Some of the important bioactive phytonutrients include polyphenols,
terpenoids, resveratrol, flavonoids, isoflavonoids, carotenoids, limonoids, glucosinolates, phytoestrogens, phytosterols,
anthocyanins, and probiotics. They play specific pharmacological effects in human health. This article reviews the current
available scientific literature regarding the effect of Nutrease powder as an effective supplementation for a daily energy
need in life style disorders like diabetes.
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Medicinal plants are being looked upon once again for the treatment of diabetes. Many conventional drugs have been derived from prototypic molecules in medicinal plants. Metformin exemplifies an efficacious oral glucose-lowering agent. To date, over 400 traditional plant treatments for diabetes have been reported, although only a small number of these have received scientific and medical evaluation to assess their efficacy. The hypoglycemic effect of some herbal extracts has been confirmed in human and animal models of type 2 diabetes. The World Health Organization Expert Committee on diabetes has recommended that traditional medicinal herbs be further investigated. The present paper Reviews the Role of Insulike tablets developed by R&D cell of Lactonova Nutripharm Pvt Ltd. Hyderabad in the role of herbal nutraceutical drug INSULIKE, A nutriphenotypic approach for the treatment of diabetes.
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Website: https://www.magnacode.co.in/treatment-for-diabetes-mellitus
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2014 Report: Medicines in Development for Diabetes
Nearly 26 million Americans are affected by diabetes—including 7 million people who are unaware they have the disease. One of the top 10 causes of death in the United States, diabetes has far-reaching implications for patients and their families and our health care system.
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Supplementing essential and conditionally essential nutrients like Nutrease powder to support essential metabolic pathways
is required for immune defense and repair, neuro-hormone balance as well as digestive and detox competencies.
Impaired antioxidant status has been shown to have a definite role in the development of insulin resistance and type 2
diabetes. Overproduction of oxidants (reactive oxygen species and reactive nitrogen species) in the human body is
responsible for the pathogenesis of some diseases. The scavenging of these oxidants is thought to be an effective measure to
depress the level of oxidative stress of organisms. It has been reported that intake of Nutrease powder is inversely associated
with the risk of many chronic diseases, and antioxidant phytochemicals in Nutrease powder are considered to be responsible
for these health benefits. Antioxidant phytochemicals found in Nutrease powder plays an important role in the prevention
and treatment of chronic diseases caused by oxidative stress. They often possess strong antioxidant and free radical
scavenging abilities, which are also the basis of other bioactivities and health benefits, such as diabetes mellitus.
Phytonutrients in Nutrease powder play a positive role by maintaining and modulating immune function to prevent specific
diseases. Being natural products, they hold a great promise in clinical therapy. Phytonutrients are the plant nutrients with
specific biological activities that support human health. Some of the important bioactive phytonutrients include polyphenols,
terpenoids, resveratrol, flavonoids, isoflavonoids, carotenoids, limonoids, glucosinolates, phytoestrogens, phytosterols,
anthocyanins, and probiotics. They play specific pharmacological effects in human health. This article reviews the current
available scientific literature regarding the effect of Nutrease powder as an effective supplementation for a daily energy
need in life style disorders like diabetes.
Diabetes natural remedies
Below is a list of common natural remedies used to treat or reduce the symptoms of Diabetes : http://www.planetayurveda.com/diabetes-cure.htm
Global Medical Cures™ | Medications for Type 2 DIABETES
Overview of Diabetes (Type 2) Medications. Discuss this with your Healthcare provider. Only you and your healthcare provider can decide on what is best for you.
DISCLAIMER-
Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices.
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INSULIKE Tablets: A Phenotypic Nutrition for Natural Sugar Balance Associate Professor in VSB Coimbatore
Diabetes is a multifactorial disease leading to several complications, and therefore demands a multiple therapeutic approach. Patients of diabetes either do not make enough insulin or their cells do not respond to insulin. In case of total lack of insulin, patients are given insulin injections. Whereas in case of those where cells do not respond to insulin many different drugs are developed taking into consideration possible disturbances in carbohydrate-metabolism. For example, to manage post-prandial hyper-glycaemia at digestive level, glucosidase inhibitors such as acarbose, miglitol and voglibose are used. These inhibit degradation of carbohydrates there by reducing the glucose absorption by the cells. To enhance glucose uptake by peripheral cells biguanide such as metformin is used. Sulphonylureas, like glibenclamide, is insulinotropic and work as secretogogue for pancreatic cells. Although several therapies are in use for treatment, there are certain limitations due to high cost and side effects such as development of hypoglycemia, weight gain, gastrointestinal disturbances, liver toxicity etc. Based on recent advances and involvement of oxidative stress in complicating diabetes mellitus, efforts are on to find suitable antidiabetic and antioxidant therapy.
Medicinal plants are being looked upon once again for the treatment of diabetes. Many conventional drugs have been derived from prototypic molecules in medicinal plants. Metformin exemplifies an efficacious oral glucose-lowering agent. To date, over 400 traditional plant treatments for diabetes have been reported, although only a small number of these have received scientific and medical evaluation to assess their efficacy. The hypoglycemic effect of some herbal extracts has been confirmed in human and animal models of type 2 diabetes. The World Health Organization Expert Committee on diabetes has recommended that traditional medicinal herbs be further investigated. The present paper Reviews the Role of Insulike tablets developed by R&D cell of Lactonova Nutripharm Pvt Ltd. Hyderabad in the role of herbal nutraceutical drug INSULIKE, A nutriphenotypic approach for the treatment of diabetes.
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If you’re concerned about controlling your Type 1 or Type 2 diabetes, try coming up with a treatment plan with your doctor, which might include medications, lifestyle changes, and regular office visits. Then, be sure to check your blood sugar every day to keep track of your blood sugar levels, using an at-home monitor or tests at your doctor’s office. You can also follow a low-calorie diet that’s high in nutrients, which will keep your blood sugar stable and control your diabetes naturally. To learn more from our Registered Nurse co-author, like what foods can help control your blood sugar, keep reading the article!
Janumet generic.pdf
Janumet contains a blend of metformin and sitagliptin. Metformin and sitagliptin are oral diabetes drugs that assist with controlling glucose levels.
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People of all ages are affected by the common condition known as diabetes. Diabetes can take several different forms. A combination of treatment strategies can be used to manage the condition effectively. It includes leading a healthy life and avoiding complications. In this blog, we will learn in detail about the different types of diabetes, including their causes and treatments. To make this post authentic with the right knowledge, we have gathered insights from the experts at Magna Centre, a renowned facility for the best diabetes treatment in Hyderabad.
Website: https://www.magnacode.co.in/treatment-for-diabetes-mellitus
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Monitoring
MONITORING Why do I need to monitor and how do I use the results?
Daily self-monitoring of blood glucose provides people with diabetes the information they need to assess how food, physical activity and medications affect their blood glucose levels. Monitoring, however, doesn’t stop there. People with diabetes also need to regularly check their blood pressure, urine ketones and weight.
Diabetes education classes instruct patients about equipment choice and selection, timing and frequency of testing, target values, and interpretation and use of results.
Problem Solving
PROBLEM SOLVING How do I deal with problems such as illness, travel and hypoglycemia?
A person with diabetes must keep their problem-solving skills sharp because on any given day, a high or low blood glucose episode or a sick day will require them to make rapid, informed decisions about food, activity and medications. This skill is continuously put to use because even after decades of living with the disease, stability is never fully attained: the disease is progressive, chronic complications emerge, life situations change and the patient is aging.
Collaboratively, diabetes educators and patients address barriers, such as physical, emotional, cognitive, and financial obstacles and develop coping strategies.
Reducing Risks
REDUCING RISKS What can I do to prevent complications?
Effective risk reduction behaviors such as smoking cessation, and regular eye, foot and dental examinations reduce diabetes complications and maximize health and quality of life. An important part of self-care is learning to understand, seek and regularly obtain an array of preventive services.
Healthy Eating
HEALTHY EATING What can I eat?
Diabetes education classes can assist people with diabetes in gaining knowledge about the effect of food on blood glucose, sources of carbohydrates and fat, appropriate meal planning and resources to assist in making food choices. Skills taught include reading labels, planning and preparing meals, measuring foods for portion control, fat control and carbohydrate counting. Barriers, such as environmental triggers and emotional, financial, and cultural factors, are also addressed.
Being Active
BEING ACTIVE Why and How should I be active?
Diabetes educators and their patients collaborate to address barriers, such as physical, environmental, psychological and time limitations. They also work together to develop an appropriate activity plan that balances food and medication with the activity level.
Taking Medications Insulin
TAKING MEDICATIONS Why take insulin? How does Insulin work?
Diabetes is a progressive condition. Depending on what type a person has, their healthcare team will be able to determine which medications they should be taking and help them understand how your medications work. They can demonstrate how to inject insulin. Effective drug therapy in combination with healthy lifestyle choices, can lower blood glucose levels, reduce the risk for diabetes complications and produce other clinical benefits.
The goal is for the patient to be knowledgeable about insulin, including its action, side effects, efficacy, toxicity, prescribed dosage, appropriate timing and frequency of administration, effect of missed and delayed doses and instructions for storage, travel and safety.
Healthy Coping
HEALTHY COPING How do I cope with Diabetes?
An important part of the diabetes educator’s work is identifying the individual’s motivation to change behavior, then helping set achievable behavioral goals and guiding the patient through multiple obstacles. They can provide support by encouraging you to talk about your concerns and fears and can help you learn what you can control and offer ways for you to cope with what you cannot.
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Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
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Physiology of Special Chemical Sensation of Taste
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
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Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
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TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...
Taking Medications Pills
- 1. Taking Medications Oral Medications for Diabetes Washington Association of Diabetes Educators www.DiabetesAnswers.org or www.WADEpage.org
- 2. Managing Diabetes: Oral Medication When people with type 2 diabetes are unable to control blood sugar sufficiently with diet and exercise, medication may be added. There are many types of diabetes pills available, and they are often used in combination. Some work by stimulating the pancreas to make more insulin, and others improve the effectiveness of insulin, or block the digestion of starches.
- 3. Know the name of your diabetes medications and where they work
- 6. Januvia Prandin (repaglinide) Glucotrol (glipizide)
- 7. Precose (acarbose) / Glyset (Miglitol )
- 9. DDP4 Inhibitors such as Januvia
- 10. Find out More Videos and Handouts you can print Washington Association of Diabetes Educators www.DiabetesAnswers.org or www.WADEpage.org