Europe has the most open access policies and mandates in the world, with over 350 of each. The Horizon 2020 program in the EU mandates open access for peer-reviewed publications while allowing funding for open access journal fees. It recommends that EU member states develop consistent open access policies and coordinate reporting and stakeholder discussions at the national and EU levels to further align open access conditions across countries. Challenges in developing open access policies at the national level include a lack of awareness, understanding and engagement among policymakers as well as some resistance to the concept of openness.