Nanotechnology offers potential benefits but also raises ethical and social issues that must be addressed. It allows redesigning all materials at the nanoscale which could have unintended consequences. To support responsible development, nanotechnology stakeholders must educate others on its risks and benefits, and guide societies toward appropriate uses. They should also alert people to technological failures and develop personal and societal understanding of related issues. A 10-step risk management model is proposed to control hazards, including identifying nanoparticles and exposure risks, assessing severity of hazards, and reviewing procedures if work or materials change.