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THE SPINAL CORD
SALVADOR S. BRILLANTES MD
Spinal Cord Function
 The Spinal Cord is a long, thin
  bundle of nervous tissue and
  support cells connected to the
  brain and located along your
  back and neck
 The spinal cord receives and
  transmits electric signals
  throughout the entire body and
  then back to the brain
 The spinal cord is protected by
  the vertebrae, which are bones
  running down your back, and
  also by cerebral spinal fluid,
  which helps to cushion the
  nerve tissue
EmBRYOLOGY & ANATOMY
   Neural tube
        18th gestational day
   Organization
        Butterfly shaped area of gray matter with surrounding white matter
 WHITE MATTER
        Consist mainly of longitudinal nerve fibers
        Ascending and Descending tracts
 GRAY MATTER
        Groups of nuclei
Anatomy
 The spinal column is divided into
  four areas: Cervical, Thoracic,
  Lumbar, and Sacral
 Each section contains nerves
  that control certain muscles of
  your body
 Each nerve has its corresponding
  vertebrate, with the exception of
  C8 which is located between the
  C7 and the T1 vertebrates
Intervertebral Disc
 Intervertebral disc

• End plate
    – Cartilaginous layer
    – Bony layer
• Apophyseal ring
Intervertebral Disc
 Fibrocartilaginous joint of the
    motion segment
   Make up ¼ the length of the
    spinal column
   Present at levels C2-C3 to L5-S1
   Allows compressive, tensile,
    and rotational motion
   Largest avascular structures in
    the body
Intervertebral Disc
 Nucleus Pulposus            Nucleus
                              Pulposus
   –   Inner structure
   –   Gelatinous
   –   High water content
   –   Resists axial forces
BLOOD SUPPLY OF SPINAL CORD
 ANTERIOR SPINAL ARTERY
 POSTERIOR SPINAL ARTERY
     RADICULAR ARTERIES
 THE GREAT RADICULAR
  ARTERY OF ADAMKIEWICS
ARTERIAL SUPPLY: 3 LONGITUDINAL ARTERIES
1. One anterior spinal artery
    •   Supplies anterior 2/3’s of the cord
    •   Covers the length of the cord via the anterior
        median fissure
2. Two posterior spinal arteries
    •   Supplies posterior 1/3 of the cord
    •   Anastomoses frequently with each other and
        with anterior spinal artery
Note: these arteries are only enough to supply the
   cervical region of the cord; remaining segments
   get there blood supply from the radicular arteries
RADICULAR ARTERIES - BRANCHES FROM:
1. VERTEBRAL ARTERY
2. DEEP CERVICAL ARTERY
3. ASCENDING CERVICAL ARTERY
4. POSTERIOR INTERCOSTAL ARTERY
5. LUMBAR ARTERY
6. LATERAL SACRAL ARTERY



*ARTERY OF ADAMKIEWICZ
-   Supplies thoracolumbar region and the
    lumbosacral enlargement of the cord
-   Usually left sided
Segmental Arteries
                At each vertebral level from T4 to the sacrum, a pair
            of SEGMENTAL ARTERIES branches posteriorly from
            the aorta to supply blood to the vertebral body, posterior
            elements, spinal cord, and costal structures.

 Anterior spinal
 artery
                                                                    Spinal
                                                                    branch
Posterior
branch
                                                                  Intercostal
                                                                  artery
                                                                   Segmental
                                                                   arteries
Anastomoses
                                                                Aorta
Venous drainage:
1. Distribution similar to arteries
2. 3 anterior and 3 posterior
   spinal sinuses and veins
3. Internal vertebral plexus
     •   Thin walled and valveless
         and surrounds dura mater
4. Path of drainage
•   Anterior and posterior spinal
    veins  venous plexus 
    vertebral veins  ascending
    lumbar veins  azygous veins
SPINAL CORD
1. Extends from foramen magnum of the occipital bone

2. 42-45 cm long

3. Adults L1-L2 disc

4. Occupies only the superior 2/3 of the canal
FIVE DIVISIONS OF SPINAL
   CORD
   1.     CERVICAL
   2.     THORACIC
   3.     LUMBAR
   4.     SACRAL
   5.     COCCYGEAL

1.Enlargement over cervical area – C4-T1
        •Forms the brachial plexus and
        innervates upper extremit
2.Enlargement over lumbosacral area –
L2-S1
        •Forms the lumbar and sacral plexus
        and innervates the lower extremity
Spinal Nerve Structures
Spinal Cord                             Foramen
 Contained in epidural space           magnum
 Network of sensory and motor
  nerves
 Firm, cord-like structure


•   Extends from foramen magnum to L1


•   Terminates at the conus             Conus
    medularis                           medularis
•   The cauda equina begins             Cauda
    below L1                            equina
•   Filum terminale extends from
    conus medularis to the coccyx
INEQUALITY OF CORD VS
   CANAL:
1. Length and obliquity of
   the lower segments
   increase due to
   increased distance of
   cord segments and
   vertebral levels
2. Lumbosacral spinal
   nerves are the longest
3. Conus medullaris –
   tapers into the filum
   terminale
4. Cauda equina
Meninges
      Within the spinal canal, the spinal cord is surrounded by the
 EPIDURAL SPACE, filled with fatty tissue, veins, and arteries. The fatty
 tissue acts as a shock absorber.

     The spinal cord is covered by MENINGES which has three layers.




 Pia mater                                                      Subarachnoid
                                                                space: filled
                                                                with CSF

                                                              Subdural space
Arachnoid
layer
        Dura mater
Dura Mater
    •Outer most covering
    •Long tubular sheath
    •Forms dural root sleeve as nerve
    exits foramen
Arachnoid Mater
    •Avascular intermediate
    •Potential space separates it from the
    dura mater
Pia Mater
    •Innermost covering
    •Adheres to spinal cord
LAYERS:
1. Extra dural space – fat loose connective tissue; anterior
    and posterior plexus of vessels

2. Dura mater
3. Subdural space – only contains a potential space
4. Arachnoid mater
5. Subarachnoid space – CSF and vessels
6. Pia mater
Spinal Nerves
      Spinal                Epidural
       cord                  space
                               Dura mater and
                               Arachnoid layers
 Dorsal root
                               Subarachnoid
                               space
Dorsal root
ganglion




                  Ventral         Peripheral
                  root            nerve
SPINAL CORD DIVISIONS
Laminae of Rexed - groupings
   Laminae I – VI located in the posterior horn
   Lamina VII  located at the lateral horn
   Laminae VIII and IX  located at the anterior horn
   Lamina X  gray substance surrounding the central canal
-Malmon MD
Thank you!




 “Out of difficulties…grow miracles’ – malmon buddy

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Spinal cord

  • 1. THE SPINAL CORD SALVADOR S. BRILLANTES MD
  • 2. Spinal Cord Function  The Spinal Cord is a long, thin bundle of nervous tissue and support cells connected to the brain and located along your back and neck  The spinal cord receives and transmits electric signals throughout the entire body and then back to the brain  The spinal cord is protected by the vertebrae, which are bones running down your back, and also by cerebral spinal fluid, which helps to cushion the nerve tissue
  • 3. EmBRYOLOGY & ANATOMY  Neural tube  18th gestational day  Organization  Butterfly shaped area of gray matter with surrounding white matter  WHITE MATTER  Consist mainly of longitudinal nerve fibers  Ascending and Descending tracts  GRAY MATTER  Groups of nuclei
  • 4. Anatomy  The spinal column is divided into four areas: Cervical, Thoracic, Lumbar, and Sacral  Each section contains nerves that control certain muscles of your body  Each nerve has its corresponding vertebrate, with the exception of C8 which is located between the C7 and the T1 vertebrates
  • 5. Intervertebral Disc  Intervertebral disc • End plate – Cartilaginous layer – Bony layer • Apophyseal ring
  • 6. Intervertebral Disc  Fibrocartilaginous joint of the motion segment  Make up ¼ the length of the spinal column  Present at levels C2-C3 to L5-S1  Allows compressive, tensile, and rotational motion  Largest avascular structures in the body
  • 7. Intervertebral Disc  Nucleus Pulposus Nucleus Pulposus – Inner structure – Gelatinous – High water content – Resists axial forces
  • 8. BLOOD SUPPLY OF SPINAL CORD  ANTERIOR SPINAL ARTERY  POSTERIOR SPINAL ARTERY  RADICULAR ARTERIES  THE GREAT RADICULAR ARTERY OF ADAMKIEWICS
  • 9. ARTERIAL SUPPLY: 3 LONGITUDINAL ARTERIES 1. One anterior spinal artery • Supplies anterior 2/3’s of the cord • Covers the length of the cord via the anterior median fissure 2. Two posterior spinal arteries • Supplies posterior 1/3 of the cord • Anastomoses frequently with each other and with anterior spinal artery Note: these arteries are only enough to supply the cervical region of the cord; remaining segments get there blood supply from the radicular arteries
  • 10. RADICULAR ARTERIES - BRANCHES FROM: 1. VERTEBRAL ARTERY 2. DEEP CERVICAL ARTERY 3. ASCENDING CERVICAL ARTERY 4. POSTERIOR INTERCOSTAL ARTERY 5. LUMBAR ARTERY 6. LATERAL SACRAL ARTERY *ARTERY OF ADAMKIEWICZ - Supplies thoracolumbar region and the lumbosacral enlargement of the cord - Usually left sided
  • 11. Segmental Arteries At each vertebral level from T4 to the sacrum, a pair of SEGMENTAL ARTERIES branches posteriorly from the aorta to supply blood to the vertebral body, posterior elements, spinal cord, and costal structures. Anterior spinal artery Spinal branch Posterior branch Intercostal artery Segmental arteries Anastomoses Aorta
  • 12.
  • 13. Venous drainage: 1. Distribution similar to arteries 2. 3 anterior and 3 posterior spinal sinuses and veins 3. Internal vertebral plexus • Thin walled and valveless and surrounds dura mater 4. Path of drainage • Anterior and posterior spinal veins  venous plexus  vertebral veins  ascending lumbar veins  azygous veins
  • 14. SPINAL CORD 1. Extends from foramen magnum of the occipital bone 2. 42-45 cm long 3. Adults L1-L2 disc 4. Occupies only the superior 2/3 of the canal
  • 15. FIVE DIVISIONS OF SPINAL CORD 1. CERVICAL 2. THORACIC 3. LUMBAR 4. SACRAL 5. COCCYGEAL 1.Enlargement over cervical area – C4-T1 •Forms the brachial plexus and innervates upper extremit 2.Enlargement over lumbosacral area – L2-S1 •Forms the lumbar and sacral plexus and innervates the lower extremity
  • 16. Spinal Nerve Structures Spinal Cord Foramen  Contained in epidural space magnum  Network of sensory and motor nerves  Firm, cord-like structure • Extends from foramen magnum to L1 • Terminates at the conus Conus medularis medularis • The cauda equina begins Cauda below L1 equina • Filum terminale extends from conus medularis to the coccyx
  • 17. INEQUALITY OF CORD VS CANAL: 1. Length and obliquity of the lower segments increase due to increased distance of cord segments and vertebral levels 2. Lumbosacral spinal nerves are the longest 3. Conus medullaris – tapers into the filum terminale 4. Cauda equina
  • 18. Meninges Within the spinal canal, the spinal cord is surrounded by the EPIDURAL SPACE, filled with fatty tissue, veins, and arteries. The fatty tissue acts as a shock absorber. The spinal cord is covered by MENINGES which has three layers. Pia mater Subarachnoid space: filled with CSF Subdural space Arachnoid layer Dura mater
  • 19. Dura Mater •Outer most covering •Long tubular sheath •Forms dural root sleeve as nerve exits foramen Arachnoid Mater •Avascular intermediate •Potential space separates it from the dura mater Pia Mater •Innermost covering •Adheres to spinal cord
  • 20. LAYERS: 1. Extra dural space – fat loose connective tissue; anterior and posterior plexus of vessels 2. Dura mater 3. Subdural space – only contains a potential space 4. Arachnoid mater 5. Subarachnoid space – CSF and vessels 6. Pia mater
  • 21. Spinal Nerves Spinal Epidural cord space Dura mater and Arachnoid layers Dorsal root Subarachnoid space Dorsal root ganglion Ventral Peripheral root nerve
  • 23. Laminae of Rexed - groupings  Laminae I – VI located in the posterior horn  Lamina VII  located at the lateral horn  Laminae VIII and IX  located at the anterior horn  Lamina X  gray substance surrounding the central canal
  • 24.
  • 26. Thank you! “Out of difficulties…grow miracles’ – malmon buddy

Editor's Notes

  1. Rexed divides the cord into 10 laminae; each lamina extends of the cord, the most dorsal is lamina I, lamina IX is the most ventral, lamina II is also the substantia gelatinosa and is the area of synapse of the spinothalamic tract, lamina IX is the site of cell bodies for the anterior horn motor cells