This document summarizes a research article that evaluated brush border enzymuria originating from proximal renal tubules as a screening test for psoriatic arthritis. The study compared diagnostic values and laboratory variables of alanine - aminopeptidase, γ-glutamyl transferase, β2-microglobuline, C Reactive Protein, and disease activity index in early diagnosis of previously untreated psoriatic arthritis patients. It examined samples from 70 participants, including 35 untreated psoriatic arthritis patients and 35 healthy controls, to determine the effect of untreated psoriatic arthritis on tubular function and sensitivity of the brush border region. The diagnostic value of enzymes originating from proximal renal tubules was also evaluated.