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Archives of Clinical
Nephrology
Peertechz Journals
Research Article
Some Aspects of the Evaluation of Brush Border Enzymuria
Originating from Proximal Renal Tubules as Screening Test in
Patients with Psoriatic Arthritis
 Dejan Spasovski*
 *Corresponding author: Dejan Spasovski, University Clinic
of Rheumatology, “Ss Ciryl and Methodius” University,
Skopje, Republic of Macedonia, Tel: +389023147-668;
 Dates: Received: 12 October, 2016; Accepted: 25
October, 2016; Published: 26 October, 2016
 Citation: Spasovski D (2016) Some Aspects of the
Evaluation of Brush Border Enzymuria Originating from
Proximal Renal Tubules as Screening Test in Patients with
Psoriatic Arthritis. Arch Clin Nephrol 2(1): 038-043.
Abstract
 Aim: To compare diagnostic values and laboratory variables of alanine -
aminopeptidase (microsomale AAP), γ-glutamyl transferase (γ−GT),β2-
microglobuline (β2-M), C Reactive Protein (CRP) and index for disease
activity (PASI) in early diagnosis in previously untreated Psoriatic
arthritis (Psa). To determine the effect of untreated Psoriatic arthritis
on tubular function, sensitivity of the Brush Border region as well as
the diagnostic value of the enzymes originating from proximal renal
tubules. Methods: From the standard methods of the International
Federation for Clinical Chemistry (IFCC) we used the kinetic method
for determination of alanine - aminopeptidase (microsomal AAP), γ-
glutamyl transferase (γ−GT) and MEIA (Microparticles Enzyme
Immunoassay(Abbot Ax sym system) for determination of β2-
microglobuline in urine. We examined samples (serum and urine) from
70 participants (35 Psa untreated, 35 healthy control group). RF and
CRP are determined with Latex agglutination test in the same
participants.
Thank you
For more information Read Online Article…
http://www.peertechz.com/Clinical-Nephrology/pdf/ACN-1-113.pdf
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Full
Article
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some-aspects-of-the-evaluation-of-brush-border-enzymuria-originating-from-proximal-renal-tubules-as-screening-test-in-patients-with-psoriatic-arthritis-archives-of-clinical-nephrology-peertechz-journals

  • 2. Research Article Some Aspects of the Evaluation of Brush Border Enzymuria Originating from Proximal Renal Tubules as Screening Test in Patients with Psoriatic Arthritis  Dejan Spasovski*  *Corresponding author: Dejan Spasovski, University Clinic of Rheumatology, “Ss Ciryl and Methodius” University, Skopje, Republic of Macedonia, Tel: +389023147-668;  Dates: Received: 12 October, 2016; Accepted: 25 October, 2016; Published: 26 October, 2016  Citation: Spasovski D (2016) Some Aspects of the Evaluation of Brush Border Enzymuria Originating from Proximal Renal Tubules as Screening Test in Patients with Psoriatic Arthritis. Arch Clin Nephrol 2(1): 038-043.
  • 3. Abstract  Aim: To compare diagnostic values and laboratory variables of alanine - aminopeptidase (microsomale AAP), γ-glutamyl transferase (γ−GT),β2- microglobuline (β2-M), C Reactive Protein (CRP) and index for disease activity (PASI) in early diagnosis in previously untreated Psoriatic arthritis (Psa). To determine the effect of untreated Psoriatic arthritis on tubular function, sensitivity of the Brush Border region as well as the diagnostic value of the enzymes originating from proximal renal tubules. Methods: From the standard methods of the International Federation for Clinical Chemistry (IFCC) we used the kinetic method for determination of alanine - aminopeptidase (microsomal AAP), γ- glutamyl transferase (γ−GT) and MEIA (Microparticles Enzyme Immunoassay(Abbot Ax sym system) for determination of β2- microglobuline in urine. We examined samples (serum and urine) from 70 participants (35 Psa untreated, 35 healthy control group). RF and CRP are determined with Latex agglutination test in the same participants.
  • 4. Thank you For more information Read Online Article… http://www.peertechz.com/Clinical-Nephrology/pdf/ACN-1-113.pdf For Full Article PDF