SNolidoPPT
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Celecoxib, branded as Celebrex, is a prescription nonsteroidal anti-inflammatory drug approved in 1998 to treat osteoarthritis, rheumatoid arthritis, and acute pain. It works by reducing COX-2 enzymes to decrease inflammation-causing prostaglandins. Long term use may increase risks of heart attack, stroke, and kidney disease. Celebrex is legally prescribed but doctors warned of heart risks in 2005 and addiction requires treatment with a medical program combining medication with therapy and exercise.
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Steroids
Steroids are hormones that our bodies produce naturally or through medication. They are secreted by the adrenal glands and have important functions like regulating carbohydrates, minerals, and reproduction. There are two main types - corticosteroids which are catabolic and anabolic-androgenic steroids which are anabolic. Steroids work by binding to receptors in cells and tissues. While they have medical uses, long term use can also cause harmful side effects. They are available in various forms like pills, inhalers, injections, and creams.
Celecoxil
El documento describe el fármaco Celecoxib, un inhibidor selectivo de la enzima COX-2 que se usa para tratar la artritis reumatoide y osteoartritis. Celecoxib fue desarrollado por GD Searle & Company y aprobado por la FDA en 1998. Actúa reduciendo la inflamación y el dolor al inhibir la producción de prostaglandinas. Se presenta en cápsulas de 100mg y 200mg y su uso requiere precaución durante el embarazo y la lactancia.
Celecoxib
Celecoxib is a prescription-only selective COX-2 inhibitor developed by Pfizer to reduce inflammation and pain. It is available under the brand names Celebrex, Celebra, and Onsenal. Celecoxib is commonly prescribed at dosages of 100-200mg daily for conditions like osteoarthritis, rheumatoid arthritis, and acute pain. Potential side effects include digestive issues like nausea and upset stomach, as well as increased risk of heart disease with long-term use.
Celecoxib
El resumen describe las ventas de medicamentos en el Mercado Público chileno en los últimos 12 meses. Los principales compradores son Cenabast, hospitales y servicios de salud, que representan el 48%, 36% y 11% respectivamente. El mercado público ha emitido órdenes de compra de medicamentos por $407.2 mil millones, un aumento del 23.2% anual. El medicamento Celecoxib representa $8.2 mil millones en ventas, con Cenabast y hospitales como los principales compradores.
Corticosteroids (steroid tablets)
Corticosteroids are synthetic hormones that are commonly used to reduce inflammation and suppress the immune system. They can treat many musculoskeletal disorders. Possible short-term side effects include poor wound healing, headaches, mood changes and weight changes. Long-term side effects may include slowing of growth, diabetes, osteoporosis and organ damage. Corticosteroid injections are often used to treat conditions like arthritis but can cause pain, infection, weakness and cartilage damage at the injection site. Some patients report side effects like heart palpitations, redness and flu-like symptoms after corticosteroid injections.
Anti-inflammatory agents and nsaids
NSAIDs are a large group of drugs that have analgesic, anti-inflammatory, and antipyretic properties. They work by inhibiting the arachidonic acid pathway and prostaglandins, which reduces pain, fever, and inflammation. Common side effects include gastrointestinal issues like ulcers, as well as renal and cardiovascular problems. Nurses monitor patients taking NSAIDs for therapeutic effects and side effects.
Pharmacology of inflammatory disease
This document provides information on inflammation, its pathophysiology, and drugs used to treat inflammation. It begins by outlining the objectives and introduction. It then discusses the mechanism of chemical mediators of inflammation like prostaglandins and leukotrienes. It explains the mechanism of action of different classes of anti-inflammatory drugs like NSAIDs, corticosteroids, and antirheumatic drugs. It describes specific drugs, their indications, mechanisms, and side effects. The goal is to explain the pathophysiology of inflammation and various drugs used to treat conditions like pain, fever, and arthritis.
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Steroids
Steroids are hormones that our bodies produce naturally or through medication. They are secreted by the adrenal glands and have important functions like regulating carbohydrates, minerals, and reproduction. There are two main types - corticosteroids which are catabolic and anabolic-androgenic steroids which are anabolic. Steroids work by binding to receptors in cells and tissues. While they have medical uses, long term use can also cause harmful side effects. They are available in various forms like pills, inhalers, injections, and creams.
Celecoxil
El documento describe el fármaco Celecoxib, un inhibidor selectivo de la enzima COX-2 que se usa para tratar la artritis reumatoide y osteoartritis. Celecoxib fue desarrollado por GD Searle & Company y aprobado por la FDA en 1998. Actúa reduciendo la inflamación y el dolor al inhibir la producción de prostaglandinas. Se presenta en cápsulas de 100mg y 200mg y su uso requiere precaución durante el embarazo y la lactancia.
Celecoxib
Celecoxib is a prescription-only selective COX-2 inhibitor developed by Pfizer to reduce inflammation and pain. It is available under the brand names Celebrex, Celebra, and Onsenal. Celecoxib is commonly prescribed at dosages of 100-200mg daily for conditions like osteoarthritis, rheumatoid arthritis, and acute pain. Potential side effects include digestive issues like nausea and upset stomach, as well as increased risk of heart disease with long-term use.
Celecoxib
El resumen describe las ventas de medicamentos en el Mercado Público chileno en los últimos 12 meses. Los principales compradores son Cenabast, hospitales y servicios de salud, que representan el 48%, 36% y 11% respectivamente. El mercado público ha emitido órdenes de compra de medicamentos por $407.2 mil millones, un aumento del 23.2% anual. El medicamento Celecoxib representa $8.2 mil millones en ventas, con Cenabast y hospitales como los principales compradores.
Corticosteroids (steroid tablets)
Corticosteroids are synthetic hormones that are commonly used to reduce inflammation and suppress the immune system. They can treat many musculoskeletal disorders. Possible short-term side effects include poor wound healing, headaches, mood changes and weight changes. Long-term side effects may include slowing of growth, diabetes, osteoporosis and organ damage. Corticosteroid injections are often used to treat conditions like arthritis but can cause pain, infection, weakness and cartilage damage at the injection site. Some patients report side effects like heart palpitations, redness and flu-like symptoms after corticosteroid injections.
Anti-inflammatory agents and nsaids
NSAIDs are a large group of drugs that have analgesic, anti-inflammatory, and antipyretic properties. They work by inhibiting the arachidonic acid pathway and prostaglandins, which reduces pain, fever, and inflammation. Common side effects include gastrointestinal issues like ulcers, as well as renal and cardiovascular problems. Nurses monitor patients taking NSAIDs for therapeutic effects and side effects.
Pharmacology of inflammatory disease
This document provides information on inflammation, its pathophysiology, and drugs used to treat inflammation. It begins by outlining the objectives and introduction. It then discusses the mechanism of chemical mediators of inflammation like prostaglandins and leukotrienes. It explains the mechanism of action of different classes of anti-inflammatory drugs like NSAIDs, corticosteroids, and antirheumatic drugs. It describes specific drugs, their indications, mechanisms, and side effects. The goal is to explain the pathophysiology of inflammation and various drugs used to treat conditions like pain, fever, and arthritis.
Teach back steroids
Steroids are synthetic drugs that mimic natural hormones in the body. They decrease inflammation and reduce immune system activity. There are different types of steroids including anabolic steroids, which build muscle, and glucocorticosteroids, which are used to treat inflammatory conditions like arthritis. People use steroids to decrease inflammation and improve athletic performance, but they can have serious side effects like acne, high blood pressure, and tendon ruptures depending on the method of administration.
Care of bone and joint diases in old age
The document discusses care of bones and joints in old age. It focuses on osteoarthritis as the most common cause of joint pain and disability. Osteoarthritis is a progressive degenerative disease characterized by cartilage degeneration and bone changes. It affects a large portion of the elderly population. Risk factors include genetics, trauma, obesity, and overuse. Treatment aims to control pain and improve function through exercise, weight control, braces, medications like NSAIDs and diacerin, and surgery like knee replacement for advanced cases. Total knee replacement, including computer assisted techniques, can replace severely damaged knee joints and relieve patients' pain and mobility issues.
Iboprofen in Dentistry
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used to treat pain, fever, and inflammation. It works by inhibiting the cyclooxygenase enzymes. Common uses include headaches, toothaches, back pain, arthritis, and minor injuries. Ibuprofen has a low risk of adverse effects compared to other NSAIDs, but can cause nausea, dyspepsia, gastrointestinal bleeding, and hypertension. It interacts with drugs like ACE inhibitors, aspirin, diuretics, and warfarin. Ibuprofen is contraindicated for those with asthma, hypertension, heart conditions, ulcers, liver or kidney disease, or who are pregnant
Otezla
Otezla is a drug created by Celgene Corporation to treat moderate to severe plaque psoriasis and psoriatic arthritis. It works by inhibiting the phosphodiesterase 4 enzyme, which reduces inflammation. Clinical studies showed patients experienced a reduction in symptoms and improvement in their conditions. Common side effects include diarrhea, nausea, and headache. Otezla provides an oral treatment option for these autoimmune disorders.
PEShare.co.uk Shared Resource
Performance enhancing drugs like anabolic steroids, human growth hormone, erythropoietin, beta blockers, stimulants, and diuretics can provide advantages like increased muscle and strength, faster recovery, steady hands, and endurance, but often have serious health risks. Side effects range from acne and baldness to heart problems, stroke, seizures, and even death in rare cases. While some seek to gain a competitive edge, these substances are banned and dangerous.
Arthroclem
The document discusses how to maintain joint function through various treatment options for arthritis including COX-2 inhibitors, nutritional supplements like glucosamine, chondroitin, MSM, and collagen, as well as a product called Arthroclem which combines these supplements and has received positive reviews and testimonials for relieving arthritis symptoms.
Arthroclem Info
The document discusses how to maintain joint function through both medical therapies like COX-2 inhibitors and nutritional supplements including glucosamine, chondroitin, MSM, and others. It describes Arthroclem, a supplement formulated by Dr. Richard Clement that contains these ingredients, and provides testimonials from patients who found relief from joint pain using Arthroclem. The document promotes Arthroclem and Richard Clement Nutrition as a trusted source for joint health supplements developed by a medical doctor.
NSAIDS Non Steroidal Anti-inflammatory Drugs
NSAIDs work by inhibiting cyclooxygenase enzymes and reducing prostaglandin production, which decreases inflammation, pain, and fever. They are used to treat conditions like arthritis, postoperative pain, fever, and headaches. NSAIDs can be non-selective inhibitors of COX-1 and COX-2, preferential COX-2 inhibitors, or selective COX-2 inhibitors. Common NSAID drugs include aspirin, ibuprofen, naproxen, diclofenac, celecoxib, and etoricoxib.
Pain killer
The document discusses painkillers and anti-depressants. It provides an overview of common pain sites and medication types used to treat pain, including nerve blockers, muscle relaxants, NSAIDs, and corticosteroids. The document then lists specific painkillers and anti-depressants, and details potential side effects like dizziness, drowsiness, and risk of addiction from long-term use. It also examines the physiological mechanisms of various painkillers and interactions with food, caffeine, supplements, and alcohol.
Natural Injections for Pain Syndromes.pptx
Lumbar facet disease could run throughout the spine that causes lower back pain. Other conditions like Sciatica, Sacrollitis and Chronic Muscle Pain can give a tough time through back pain. Patients can seek accurate diagnosis with Dr. Todd Koppel and seek Lumbar Injection Therapy for best treatment. Using Lumbar Epidural Steroid Injection therapy has helped patients recover fully to their happy lives. Get in touch to schedule an appointment.
Renuva disc updated- Morocco
This document discusses spinal decompression as a non-surgical treatment for back and neck pain. It provides statistics showing increasing rates of back pain and high failure rates of surgeries and medications. Spinal decompression works by applying traction to decrease pressure in the discs and draw herniations back in. Research shows it can significantly reduce herniations and relieve pain in 71-90% of patients. The treatment involves 12-15 minute sessions 3 times per week for 2-4 weeks. It is a safe and effective alternative to surgery or long-term medication use for disc issues and related pain.
analgesics
This document discusses drugs used to treat pain and inflammation. It defines acute and chronic pain, as well as neuropathic and inflammatory pain. Nociceptors detect painful stimuli. NSAIDs like aspirin and ibuprofen work by inhibiting prostaglandin synthesis to reduce pain and inflammation. Steroidal anti-inflammatory drugs also reduce inflammation. NSAIDs can cause side effects like ulcers, bleeding, and kidney damage, so should be used carefully.
Pcp
PCP was originally developed in 1926 and patented in 1952 as an anesthetic with the scientific name piperidinocychlohexanecarbonitrile. It was tested on animals before being used on humans, and was classified as an anesthetic after the Parke-Davis company tested it on humans and brought it to the federal government. PCP has legal pharmaceutical uses but is also an illegal recreational drug known by nicknames like "Angel Dust" and "Embalming Fluid." Short term effects include changes in body awareness and hallucinations, while long term risks are addiction and craving. Treatment for PCP users often occurs in emergency rooms.
Inhalants
Inhalants are breathable chemical vapors that are intentionally inhaled for their mind-altering effects. Short term effects include loss of self-control, violence, vomiting and death from suffocation. Long term effects involve weight loss, fatigue, organ damage and tolerance. Types of inhalants are volatile solvents, nitrites and anesthetics. While inhalant use is not explicitly illegal, it can cause serious health risks. Resources for information on inhalants are provided.
Inhalants
This document discusses inhalants, which are chemical vapors that are intentionally inhaled for their mind-altering effects. It describes the short-term effects like loss of control and long-term effects like damage to organs. It also covers different types of inhalants like volatile solvents, nitrites, and anesthetics. While some inhalants themselves may be legal, intentionally inhaling them to get high is considered illegal.
Meter.ppt
Heroin is an opiate narcotic derived from morphine that was first produced in 1898 and was considered a "wonder drug" until restrictions were put in place. It can be injected, smoked, or snorted and has many street names. Long term effects include lack of patience and tolerance while short term effects include flushing and drowsiness. Heroin is now illegal to possess without a license in many countries. Treatment options include quickly seeking help at a methadone clinic, behavioral therapy, and having a positive support system.
Meter
Heroin is an opiate narcotic derived from morphine that was first produced in 1898 and was considered a "wonder drug" until restrictions were put in place. It can be injected, smoked, or snorted and has many street names. Long term effects include lack of patience and tolerance while short term effects include flushing and drowsiness. Heroin is now illegal to possess without a license in many countries. Treatment options include going to a methadone clinic, behavioral therapy, and having a positive support system.
MBermejo.ppt
Phencyclidine (PCP) is a hallucinogenic drug known by names like angel dust and zombie weed. It causes schizophrenia-like symptoms such as hallucinations and delirium by affecting the brain. While there are no medications to treat PCP abuse, common treatments involve rehabilitation and behavioral therapies.
PTsangJSales
Caffeine has a long history of consumption dating back to 2700 BC in China. It originated from coffee beans in Africa in the 6th century AD and was used as currency. Caffeine is classified as a mild stimulant that raises blood pressure, heart rate, and alertness. While caffeine provides mild effects, long term overuse can lead to health issues like heart problems or nervous disorders. Common foods and drinks containing caffeine include coffee, tea, soft drinks, and chocolate.
C hearn's ppt
Tobacco is an agricultural product made from the leaves of plants in the genus Nicotiana. It has various uses such as an organic pesticide, in some medicines, and as a recreational drug and cash crop. The document then discusses the history and origins of tobacco, its various uses and forms of consumption, slang terms, health effects, and common treatments for quitting tobacco use.
Crystal meth
Crystal meth was first developed in 1893 from ephedrine and was turned into its crystallized form in 1919. By the 1960s, crystal meth was increasingly used illegally and San Diego became the North American capital. Crystal meth is a stimulant that goes by many names and its use can lead to serious health issues like infections, collapsed veins, pneumonia, liver and kidney disease, as well as violent and anxious behavior.
H rabipe ppt_jnhj
People have used marijuana and hemp for thousands of years, but in the 20th century a powerful individual made it illegal worldwide due to moral objections. Marijuana was recently reclassified under UK drug laws, and while it has nicknames like ganja and herb, it can negatively impact health by increasing heart rate and risk of cancer, panic attacks, and memory loss or coordination issues in both short and long term use. Treatments include rehabilitation programs and lifestyle changes.
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Teach back steroids
Steroids are synthetic drugs that mimic natural hormones in the body. They decrease inflammation and reduce immune system activity. There are different types of steroids including anabolic steroids, which build muscle, and glucocorticosteroids, which are used to treat inflammatory conditions like arthritis. People use steroids to decrease inflammation and improve athletic performance, but they can have serious side effects like acne, high blood pressure, and tendon ruptures depending on the method of administration.
Care of bone and joint diases in old age
The document discusses care of bones and joints in old age. It focuses on osteoarthritis as the most common cause of joint pain and disability. Osteoarthritis is a progressive degenerative disease characterized by cartilage degeneration and bone changes. It affects a large portion of the elderly population. Risk factors include genetics, trauma, obesity, and overuse. Treatment aims to control pain and improve function through exercise, weight control, braces, medications like NSAIDs and diacerin, and surgery like knee replacement for advanced cases. Total knee replacement, including computer assisted techniques, can replace severely damaged knee joints and relieve patients' pain and mobility issues.
Iboprofen in Dentistry
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used to treat pain, fever, and inflammation. It works by inhibiting the cyclooxygenase enzymes. Common uses include headaches, toothaches, back pain, arthritis, and minor injuries. Ibuprofen has a low risk of adverse effects compared to other NSAIDs, but can cause nausea, dyspepsia, gastrointestinal bleeding, and hypertension. It interacts with drugs like ACE inhibitors, aspirin, diuretics, and warfarin. Ibuprofen is contraindicated for those with asthma, hypertension, heart conditions, ulcers, liver or kidney disease, or who are pregnant
Otezla
Otezla is a drug created by Celgene Corporation to treat moderate to severe plaque psoriasis and psoriatic arthritis. It works by inhibiting the phosphodiesterase 4 enzyme, which reduces inflammation. Clinical studies showed patients experienced a reduction in symptoms and improvement in their conditions. Common side effects include diarrhea, nausea, and headache. Otezla provides an oral treatment option for these autoimmune disorders.
PEShare.co.uk Shared Resource
Performance enhancing drugs like anabolic steroids, human growth hormone, erythropoietin, beta blockers, stimulants, and diuretics can provide advantages like increased muscle and strength, faster recovery, steady hands, and endurance, but often have serious health risks. Side effects range from acne and baldness to heart problems, stroke, seizures, and even death in rare cases. While some seek to gain a competitive edge, these substances are banned and dangerous.
Arthroclem
The document discusses how to maintain joint function through various treatment options for arthritis including COX-2 inhibitors, nutritional supplements like glucosamine, chondroitin, MSM, and collagen, as well as a product called Arthroclem which combines these supplements and has received positive reviews and testimonials for relieving arthritis symptoms.
Arthroclem Info
The document discusses how to maintain joint function through both medical therapies like COX-2 inhibitors and nutritional supplements including glucosamine, chondroitin, MSM, and others. It describes Arthroclem, a supplement formulated by Dr. Richard Clement that contains these ingredients, and provides testimonials from patients who found relief from joint pain using Arthroclem. The document promotes Arthroclem and Richard Clement Nutrition as a trusted source for joint health supplements developed by a medical doctor.
NSAIDS Non Steroidal Anti-inflammatory Drugs
NSAIDs work by inhibiting cyclooxygenase enzymes and reducing prostaglandin production, which decreases inflammation, pain, and fever. They are used to treat conditions like arthritis, postoperative pain, fever, and headaches. NSAIDs can be non-selective inhibitors of COX-1 and COX-2, preferential COX-2 inhibitors, or selective COX-2 inhibitors. Common NSAID drugs include aspirin, ibuprofen, naproxen, diclofenac, celecoxib, and etoricoxib.
Pain killer
The document discusses painkillers and anti-depressants. It provides an overview of common pain sites and medication types used to treat pain, including nerve blockers, muscle relaxants, NSAIDs, and corticosteroids. The document then lists specific painkillers and anti-depressants, and details potential side effects like dizziness, drowsiness, and risk of addiction from long-term use. It also examines the physiological mechanisms of various painkillers and interactions with food, caffeine, supplements, and alcohol.
Natural Injections for Pain Syndromes.pptx
Lumbar facet disease could run throughout the spine that causes lower back pain. Other conditions like Sciatica, Sacrollitis and Chronic Muscle Pain can give a tough time through back pain. Patients can seek accurate diagnosis with Dr. Todd Koppel and seek Lumbar Injection Therapy for best treatment. Using Lumbar Epidural Steroid Injection therapy has helped patients recover fully to their happy lives. Get in touch to schedule an appointment.
Renuva disc updated- Morocco
This document discusses spinal decompression as a non-surgical treatment for back and neck pain. It provides statistics showing increasing rates of back pain and high failure rates of surgeries and medications. Spinal decompression works by applying traction to decrease pressure in the discs and draw herniations back in. Research shows it can significantly reduce herniations and relieve pain in 71-90% of patients. The treatment involves 12-15 minute sessions 3 times per week for 2-4 weeks. It is a safe and effective alternative to surgery or long-term medication use for disc issues and related pain.
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This document discusses drugs used to treat pain and inflammation. It defines acute and chronic pain, as well as neuropathic and inflammatory pain. Nociceptors detect painful stimuli. NSAIDs like aspirin and ibuprofen work by inhibiting prostaglandin synthesis to reduce pain and inflammation. Steroidal anti-inflammatory drugs also reduce inflammation. NSAIDs can cause side effects like ulcers, bleeding, and kidney damage, so should be used carefully.
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PCP was originally developed in 1926 and patented in 1952 as an anesthetic with the scientific name piperidinocychlohexanecarbonitrile. It was tested on animals before being used on humans, and was classified as an anesthetic after the Parke-Davis company tested it on humans and brought it to the federal government. PCP has legal pharmaceutical uses but is also an illegal recreational drug known by nicknames like "Angel Dust" and "Embalming Fluid." Short term effects include changes in body awareness and hallucinations, while long term risks are addiction and craving. Treatment for PCP users often occurs in emergency rooms.
Inhalants
Inhalants are breathable chemical vapors that are intentionally inhaled for their mind-altering effects. Short term effects include loss of self-control, violence, vomiting and death from suffocation. Long term effects involve weight loss, fatigue, organ damage and tolerance. Types of inhalants are volatile solvents, nitrites and anesthetics. While inhalant use is not explicitly illegal, it can cause serious health risks. Resources for information on inhalants are provided.
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Heroin is an opiate narcotic derived from morphine that was first produced in 1898 and was considered a "wonder drug" until restrictions were put in place. It can be injected, smoked, or snorted and has many street names. Long term effects include lack of patience and tolerance while short term effects include flushing and drowsiness. Heroin is now illegal to possess without a license in many countries. Treatment options include going to a methadone clinic, behavioral therapy, and having a positive support system.
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Crystal meth was first developed in 1893 from ephedrine and was turned into its crystallized form in 1919. By the 1960s, crystal meth was increasingly used illegally and San Diego became the North American capital. Crystal meth is a stimulant that goes by many names and its use can lead to serious health issues like infections, collapsed veins, pneumonia, liver and kidney disease, as well as violent and anxious behavior.
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The Electrocardiogram - Physiologic Principles
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
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- 1. By: Shelnika Nolido and Priyana Patel
- 2. History • Brand name for a drug compound: Celecoxib • Approved on December 31, 1998 by United States Food and Drug Administration (FDA) • Developed by G.D. Searle and Company • Involved in disputes about the chemicals in the drug • 2005- Accused by doctors that the drug would increase risk for heart attacks
- 3. Classification • Pain Reliever • An NSAID (Non-Steroidal Anti-Inflammatory Drug) • Relieves symptoms of: • Osteoarthritis: Breakdown of cartilage in the joints, causes pain, stiffness and swelling • Rheumatoid arthritis: A chronic disease of swelling of joints • Pain following dental or surgical procedures
- 4. Nicknames • Celebrex is the brand name for Celecoxib
- 5. How the Drug affects the Body • COX-2 enzymes makes the body produce Prostaglandins which triggers inflammation. • It triggers the inflammation in the arthritic spots. • When taken, Celebrex reduces COX-2 enzymes which reduce the production of Prostaglandins, which reduces inflammation.
- 6. Legal/Illegal • Celebrex is a legal prescription drug used as treatment for signs and symptoms of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and for the management of acute pain in adults.
- 7. Possible Dangers of Celebrex Usage • Short-term effects ▫ Constipation ▫ Diarrhea ▫ Dizziness ▫ Gas ▫ Headache ▫ Heartburn ▫ Nausea ▫ Sore throat ▫ Stomach upset ▫ Stuffy nose ▫ Allergic reaction: hives, difficulty breathing • Long-term effects ▫ Increases your risk for heart attack ▫ Increases your risk for stroke ▫ Kidney disease ▫ Death
- 8. Treatment for Celebrex Addiction • Working with your Doctor - Right prescription drug addiction Program • Sometimes combined with exercise, physical therapy, and therapy for depression
- 9. Resources Used • http://osteoarthritis.about.com/od/osteoarthritismedications/a/celebrex.htm • http://www.celebrex.com/default.aspx • http://www.drugs.com/sfx/celebrex-side-effects.html • http://www.ehow.com/about_5031481_history-celebrex.html • http://health.kosmix.com/topic/Non_steroidal_anti_inflammatory_drug • http://www.medicinenet.com/script/main/art.asp?articlekey=50318 • http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001050 • http://www.themedicine.net/drugs/celebrex.html • www.dictionary.com
- 10. The End