Shared Decision Making in health (Decisions Compartides) is a project of the Catalan Health Ministry of the Generalitat de Catalunya. Physicians and patients are involved in shared medical decisions. Both parties share information (evidence based information about treatment options, cons and pros, patient preferences and values) and an agreement is reached on the treatment to implement.
Essencial "Adding value to clinical practice" is an initiative which identifies low-value clinical practices and promotes recommendations on how to avoid them.
The Observatory of Innovation in Healthcare Management in Catalonia is the instrument used by the Catalan health system to catalogue the efforts made by organisations in innovating in several spheres of management. See more information at http://oigs.gencat.cat
April 18, 2018
Decision aids can be highly-effective tools to promote shared decision making and support patients in becoming engaged participants in their healthcare. Join us for the first-ever convening with leaders behind a Washington experiment in certifying decision aids, as state officials, health systems, and on-the-ground implementation experts share lessons learned and discuss policy recommendations for national or statewide approaches to decision aid certification.
For more information, visit our website at: http://petrieflom.law.harvard.edu/events/details/decision-aids-for-patients-with-serious-illness
Presentation in the framework of the International Conference "10th anniversary of the Spanish Network of Health Technology Assessment Agencies. Towads patient and public engagement in HTA" Zaragoza 27-28 April 2017
Presentation in the framework of the International Conference "10th anniversary of the Spanish Network of Health Technology Assessment Agencies. Towads patient and public engagement in HTA" Zaragoza 27-28 April 2017
Presentation in the framework of the International Conference "10th anniversary of the Spanish Network of Health Technology Assessment Agencies. Towads patient and public engagement in HTA" Zaragoza 27-28 April 2017
Closing the Loop: Strategies to Extend Care in the EDEngagingPatients
This HIMSS15 presentation discusses the challenges faced in hospital emergency departments and offers insights for implementing a process to follow up with discharged ED patients to enhance outcomes and satisfaction,while optimizing utilization and reducing risk.
Essencial "Adding value to clinical practice" is an initiative which identifies low-value clinical practices and promotes recommendations on how to avoid them.
The Observatory of Innovation in Healthcare Management in Catalonia is the instrument used by the Catalan health system to catalogue the efforts made by organisations in innovating in several spheres of management. See more information at http://oigs.gencat.cat
April 18, 2018
Decision aids can be highly-effective tools to promote shared decision making and support patients in becoming engaged participants in their healthcare. Join us for the first-ever convening with leaders behind a Washington experiment in certifying decision aids, as state officials, health systems, and on-the-ground implementation experts share lessons learned and discuss policy recommendations for national or statewide approaches to decision aid certification.
For more information, visit our website at: http://petrieflom.law.harvard.edu/events/details/decision-aids-for-patients-with-serious-illness
Presentation in the framework of the International Conference "10th anniversary of the Spanish Network of Health Technology Assessment Agencies. Towads patient and public engagement in HTA" Zaragoza 27-28 April 2017
Presentation in the framework of the International Conference "10th anniversary of the Spanish Network of Health Technology Assessment Agencies. Towads patient and public engagement in HTA" Zaragoza 27-28 April 2017
Presentation in the framework of the International Conference "10th anniversary of the Spanish Network of Health Technology Assessment Agencies. Towads patient and public engagement in HTA" Zaragoza 27-28 April 2017
Closing the Loop: Strategies to Extend Care in the EDEngagingPatients
This HIMSS15 presentation discusses the challenges faced in hospital emergency departments and offers insights for implementing a process to follow up with discharged ED patients to enhance outcomes and satisfaction,while optimizing utilization and reducing risk.
This workshop will look at patient care pathways and demonstrate how simulation can combine process flow across; services, clinical best practice and the progression of patients through disease states, to test the impact of improvement initiatives on patient care, outcomes, costs and resource utilization.
Using examples from recent projects on simulating care pathways within HIV services, and simulating future service needs for dementia care, we show the results of combining disease progression with service utilization.
In the workshop, we’ll consider what the ideal pathway model would look like and invite you to work with us to build a pathway using our latest technology.
Presented at the 2015 IHI International Forum byThe Royal Melbourne Hospital of Victoria,Australia, this poster,speaks to the power of Shadowing to engage patients and families in decisions of care, specifically the post-discharge planning process.
This resource summarizes the eight recommendations outlined in the Institute of Medicine's a new consensus study entitled, Improving Diagnosis in Health Care. The recommendations are aimed at making diagnoses more accurate, reliable, efficient, and safe. This work is a continuation of the IOM’s Quality Chasm series.
In first of two-part series, Pamela Greenhouse explores the differences and similarities of the Patient and Family Centered Care Methodology and Practice (PFCC M/P) and leean process improvement approachs, such as Lean, Six Sigma and Toyota. She believes that the PFCC M/P can be the unifying theme for health care, incorporating both process improvement and performance improvement.
Enhancing the patient experience in a new purpose-build MDT meeting room with...Cancer Institute NSW
St Vincent’s Head and Neck Clinic is a well-established, multidisciplinary clinic which has provided a co-ordinated team approach to the head and neck patient’s complex needs for over three decades. With the development of a new, purpose-built cancer facility, a clinical redesign project was undertaken, with the aim to further enhancing the patient experience and improving the quality of care for patients attending the weekly Multidisciplinary Head and Neck Clinic.
Director of Strategy and Development, Australian Commission on Safety and Quality in Healthcare.
Presentation given at "Health Literacy Network: Crossing Disciplines, Bridging Gaps", November 26, 2013. The University of Sydney.
PFCC INFOGRAPHIC: Six Steps to Patient EngagementEngagingPatients
The challenges of creating patient and family-centered care seem daunting. However, the PFCC Innovation Center of UPMC demonstrates it's easier than you think. In this infographic, you see it begins by engaging patients through a simple six step process.
The best of clinical pathway redesign - practical examples of delivering bene...NHS Improvement
The examples here showcase just some of the innovations that have enabled thousands of patients to enjoy better health and well-being thanks to practicalservice improvements implemented on various clinical pathways
April 18, 2018
Decision aids can be highly-effective tools to promote shared decision making and support patients in becoming engaged participants in their healthcare. Join us for the first-ever convening with leaders behind a Washington experiment in certifying decision aids, as state officials, health systems, and on-the-ground implementation experts share lessons learned and discuss policy recommendations for national or statewide approaches to decision aid certification.
For more information, visit our website at: http://petrieflom.law.harvard.edu/events/details/decision-aids-for-patients-with-serious-illness
Please share this slideshow with anyone who may be interested!
Watch all our webinars: https://www.youtube.com/playlist?list=PL4dDQscmFYu_ezxuxnAE61hx4JlqAKXpR
In this webinar:
● Discussion of the CADTH Symposium
● Recommendations for HTA improvements in Canada
● Audience Q&A
View the video: https://youtu.be/AJCOemf2r6Y
Follow our social media accounts:
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This workshop will look at patient care pathways and demonstrate how simulation can combine process flow across; services, clinical best practice and the progression of patients through disease states, to test the impact of improvement initiatives on patient care, outcomes, costs and resource utilization.
Using examples from recent projects on simulating care pathways within HIV services, and simulating future service needs for dementia care, we show the results of combining disease progression with service utilization.
In the workshop, we’ll consider what the ideal pathway model would look like and invite you to work with us to build a pathway using our latest technology.
Presented at the 2015 IHI International Forum byThe Royal Melbourne Hospital of Victoria,Australia, this poster,speaks to the power of Shadowing to engage patients and families in decisions of care, specifically the post-discharge planning process.
This resource summarizes the eight recommendations outlined in the Institute of Medicine's a new consensus study entitled, Improving Diagnosis in Health Care. The recommendations are aimed at making diagnoses more accurate, reliable, efficient, and safe. This work is a continuation of the IOM’s Quality Chasm series.
In first of two-part series, Pamela Greenhouse explores the differences and similarities of the Patient and Family Centered Care Methodology and Practice (PFCC M/P) and leean process improvement approachs, such as Lean, Six Sigma and Toyota. She believes that the PFCC M/P can be the unifying theme for health care, incorporating both process improvement and performance improvement.
Enhancing the patient experience in a new purpose-build MDT meeting room with...Cancer Institute NSW
St Vincent’s Head and Neck Clinic is a well-established, multidisciplinary clinic which has provided a co-ordinated team approach to the head and neck patient’s complex needs for over three decades. With the development of a new, purpose-built cancer facility, a clinical redesign project was undertaken, with the aim to further enhancing the patient experience and improving the quality of care for patients attending the weekly Multidisciplinary Head and Neck Clinic.
Director of Strategy and Development, Australian Commission on Safety and Quality in Healthcare.
Presentation given at "Health Literacy Network: Crossing Disciplines, Bridging Gaps", November 26, 2013. The University of Sydney.
PFCC INFOGRAPHIC: Six Steps to Patient EngagementEngagingPatients
The challenges of creating patient and family-centered care seem daunting. However, the PFCC Innovation Center of UPMC demonstrates it's easier than you think. In this infographic, you see it begins by engaging patients through a simple six step process.
The best of clinical pathway redesign - practical examples of delivering bene...NHS Improvement
The examples here showcase just some of the innovations that have enabled thousands of patients to enjoy better health and well-being thanks to practicalservice improvements implemented on various clinical pathways
April 18, 2018
Decision aids can be highly-effective tools to promote shared decision making and support patients in becoming engaged participants in their healthcare. Join us for the first-ever convening with leaders behind a Washington experiment in certifying decision aids, as state officials, health systems, and on-the-ground implementation experts share lessons learned and discuss policy recommendations for national or statewide approaches to decision aid certification.
For more information, visit our website at: http://petrieflom.law.harvard.edu/events/details/decision-aids-for-patients-with-serious-illness
Please share this slideshow with anyone who may be interested!
Watch all our webinars: https://www.youtube.com/playlist?list=PL4dDQscmFYu_ezxuxnAE61hx4JlqAKXpR
In this webinar:
● Discussion of the CADTH Symposium
● Recommendations for HTA improvements in Canada
● Audience Q&A
View the video: https://youtu.be/AJCOemf2r6Y
Follow our social media accounts:
Twitter - https://twitter.com/survivornetca
Facebook - https://www.facebook.com/CanadianSurvivorNet
Pinterest - https://www.pinterest.com/survivornetwork
YouTube - https://www.youtube.com/user/Survivornetca
How to make care and support planning a two-way dynamic - presentation from webinar held on 1 October 2014
This relates to the first NHS IQ Long Term Conditions Improvement Programmes Wednesday Lunch & Learn Webinar Series. How to make care and support planning a 2 way dynamic hosted by Dr Alan Nye & Brook Howells from AQuA. This webinar discussed how to encourage patients, carers and the public to work alongside (in equal partnership) with clinicians and managers
Module 5 (week 9) - InterventionAs you continue to work on your .docxroushhsiu
Module 5 (week 9) - Intervention
As you continue to work on your assignment, you will be pulling in some information from your work throughout this course. For one part of this presentation, you will be identifying the current problem (or opportunity for change). This was part of your discussion in the week 2 assignment PowerPoint.
You will also propose an evidence-based intervention to address this particular problem. This intervention should be derived from the literature you have found and presented in your critical appraisal template.
As you have seen, these assignments have provided you the ability to identify a problem, develop a PCIOT question, search for evidence related to this PICOT, critically appraise the evidence for a solution to the problem, and now you will identify the solution and disseminate the results.
You are well on your way to becoming evidence-based practitioners!
Week 9!
Nice work on last week’s discussion. As you have discovered, decision aids can be very helpful when providing information for patients and families.
This week, you will continue to work on your assignment for this module. This will be an 8-9 slide PowerPoint presentation in which you will recommend an evidence-based practice change. Review the 4 articles you critiqued to determine what practice change is supported by the literature.
Some of the content for this assignment will be taken from your previous work and some will be new. This PowerPoint is a total of 8-9 slides.
Please review the full assignment details located under the learning resources for module 5.
Please let me know if you have questions
David
Provider perspectives on the utility of a colorectal
cancer screening decision aid for facilitating shared
decision making
Paul C. Schroy III MD MPH,* Shamini Mylvaganam MPH� and Peter Davidson MD�
*Director of Clinical Research, Section of Gastroenterology, Boston Medical Center, Boston, MA, �Study Coordinator, Section of
Gastroenterology, Boston Medical Center, Boston, MA and �Clinical Director, Section of General Internal Medicine, Boston
Medical Center, Boston, MA, USA
Correspondence
Paul C. Schroy III, MD MPH
Boston Medical Center
85 E. Concord Street
Suite 7715
Boston
MA 02118
USA
E-mail: [email protected]
Accepted for publication
8 August 2011
Keywords: decision aids, informed
decision making, shared decision
making
Abstract
Background Decision aids for colorectal cancer (CRC) screening
have been shown to enable patients to identify a preferred screening
option, but the extent to which such tools facilitate shared decision
making (SDM) from the perspective of the provider is less well
established.
Objective Our goal was to elicit provider feedback regarding the
impact of a CRC screening decision aid on SDM in the primary care
setting.
Methods Cross-sectional survey.
Participants Primary care providers participating in a clinical trial
evaluating the impact of a novel CRC screening d ...
Needs Analysis of Primary Care Physicians and Other Providers in Terms of Obe...Clinical Tools, Inc
Tanner, B. Needs Analysis of Primary Care Physicians and
Other Providers in Terms of Obesity Training. Poster
presented Overcoming Obesity: Diagnose. Personalize.
Treat. Conference of the American Society of Bariatric
Physicians, September 12, 2014 Austin Texas.
Angela Coulter: Getting the best value for patientsThe King's Fund
Dr Angela Coulter, Director of Global Initiatives, Foundation for Informed Medical Decision Making, spoke at The King's Fund's 'Reducing unwarranted variations in health care' conference, giving her expert opinion on how to give the best value for patients: with the right intervention, in the right place, at the right time with the right level of involvement.
Isn't this about me? The role of patients and the public in implementing evid...NEQOS
Master Class, led by Professor Richard Thomson- focusing on the role of patients and public in implementing evidence-based healthcare- including shared decision making
Rob Reid: Redesigning primary care: the Group Health journeyThe King's Fund
Rob Reid, Senior Investigator at Group Health Research Institute, explains the journey taken by Group Health in support of integrated primary care. A case study in how primary care can be delivered effectively and efficiently to a population, Rob laid out the challenges facing general practice in the States, and how Group Health worked to improve the situation for both patients and the workforce.
Similar to Shared Decision Making in Health in Catalonia (20)
Poster presented at the ISPOR (The Professional Society for Health Economics and Outcomes Research) in Barcelona 10-14 November 2018 under the legend "New Perspectives for Improving 21st Century Health Systems"
Análisis de 2 invervenciones innovadores proyecto europeo SUSTAIN-COPE H2020. SUSTAIN es un proyecto de investigación a escala europea, cuyas siglas en inglés significan Atención Integrada, Adaptada y Sostenible para Personas Mayores de Europa www.sustain-eu.org/es/
Millora de l’atenció social i sanitària per a persones de 65+ anys de Sabadell Nord, mitjançant l’elaboració conjunta d’un Pla Individualitzat d’Atenció Integrada Social i Salut. Iniciativa en el marc del projecte SUSTAIN és un projecte de recerca a escala europea que, a partir de les seves sigles en anglès, vol dir Atenció Integrada, Adaptada i Sostenible per a la Gent Gran d’Europa http://www.sustain-eu.org/ca/
Recomanació del projecte Essencial per a pacients sobre intervencions sanitàries de poc valor que indica: "No s’han de prendre de forma rutinària medicaments sedants per al tractament d’aquest tipus de vertigen". +info http://essencialsalut.gencat.cat
La melatonina (N-acetil-5-metoxitriptamina) és una neurohormona endògena produïda principalment, però no exclusivament, per la glàndula pineal. Actua mitjançant els receptors MT1, MT2 i MT3 del nucli supraquiasmàtic de l’hipotàlem anterior que és l’autèntic rellotge biològic. La melatonina es pot obtenir de fonts naturals, però la majoria és d’origen sintètic. Amb l’edat es redueix la seva secreció natural.
D’ençà del seu descobriment el 1958, la melatonina ha estat subjecte a una gran quantitat creixent d’estudis, descobrint-se múltiples accions fisiològiques que fa que quasi adquireixi la qualitat de “molècula miraculosa” per la seva ubiqüitat i nombre d’activitats en les quals participa (antioxidant, neuroprotectora, anticàncer, immunomoduladora, etc.). +info http://aquas.gencat.cat
Recomanació del projecte Essencial per a pacients sobre intervencions sanitàries de poc valor que indica: "Els nens i les nenes amb rinosinusitis no haurien de prendre antibiòtics de forma rutinària". +info http://essencialsalut.gencat.cat
Recomanació del projecte Essencial per a pacients sobre intervencions sanitàries de poc valor que indica: "El metge valorarà el seu risc de patir alguna malaltia cardiovascular i en el cas de que sigui baix no caldrà prendre medicaments". +info http://essencialsalut.gencat.cat
Recomanació del projecte Essencial per a pacients sobre intervencions sanitàries de poc valor que indica: "En nens i nenes no cal fer de forma rutinària radiografies de tòrax per diagnosticar la bronquiolitis". +info http://essencialsalut.gencat.cat
Recomanació del projecte Essencial per a pacients sobre intervencions sanitàries de poc valor que indica: "No s'haurien d'alternar medicaments per al tractament de la febre en infants". +info http://essencialsalut.gencat.cat
Díptico informativo para pacientes y profesionales de la salud donde se explica qué son las decisiones compartidas como herramienta de diálogo y consenso para tomar las mejores decisiones respecto a las alternativas diagnósticas, terapéuticas y rehabilitadoras.
Fullet per a pacients i professionals de la salut on s'explica què són les decisions compartides com a eina de diàleg i consens a l'hora de prendre les millor alternatives diagnòstiques, terapèutiques i rehabilitadores.
"Les persones amb malalties del cor, renals o malalties del fetge no haurien de prendre de manera rutinària antiinflamatoris no esteroïdals (tipus aspirina, ibuprofèn o naproxèn)". RECOMANACIÓ ESSENCIAL per a pacients. Essencial és una iniciativa de l’Agència de Qualitat i Avaluació Sanitàries (AQuAS) del Departament de Salut de la Generalitat de Catalunya que identifica pràctiques clíniques de poc valor i promou recomanacions per tal d’evitar-ne la realització. Aquestes recomanacions són consensuades i avalades per les societats científiques, els professionals sanitaris, els pacients i l’AQuAS.
"Les persones que pateixen depressions lleus no haurien de prendre de manera rutinària antidepressius, excepte si tenen antecedents o factors de risc associats". RECOMANACIÓ ESSENCIAL per a pacients. Essencial és una iniciativa de l’Agència de Qualitat i Avaluació Sanitàries (AQuAS) del Departament de Salut de la Generalitat de Catalunya que identifica pràctiques clíniques de poc valor i promou recomanacions per tal d’evitar-ne la realització. Aquestes recomanacions són consensuades i avalades per les societats científiques, els professionals sanitaris, els pacients i l’AQuAS.
"La bronquiolitis en lactants no s'hauria de tractar de forma rutinària amb broncodilatadors (tipus salbutamol)". RECOMANACIÓ ESSENCIAL per a pacients. Essencial és una iniciativa de l’Agència de Qualitat i Avaluació Sanitàries (AQuAS) del Departament de Salut de la Generalitat de Catalunya que identifica pràctiques clíniques de poc valor i promou recomanacions per tal d’evitar-ne la realització. Aquestes recomanacions són consensuades i avalades per les societats científiques, els professionals sanitaris, els pacients i l’AQuAS.
"No és recomanable l’ús de faixes o suports lumbars per tractar o prevenir la lumbàlgia". RECOMANACIÓ ESSENCIAL per a pacients. Essencial és una iniciativa de l’Agència de Qualitat i Avaluació Sanitàries (AQuAS) del Departament de Salut de la Generalitat de Catalunya que identifica pràctiques clíniques de poc valor i promou recomanacions per tal d’evitar-ne la realització. Aquestes recomanacions són consensuades i avalades per les societats científiques, els professionals sanitaris, els pacients i l’AQuAS.
"Les persones grans no cal que prenguin de forma rutinària vitamina D per reduir el risc de caigudes". RECOMANACIÓ ESSENCIAL per a pacients. Essencial és una iniciativa de l’Agència de Qualitat i Avaluació Sanitàries (AQuAS) del Departament de Salut de la Generalitat de Catalunya que identifica pràctiques clíniques de poc valor i promou recomanacions per tal d’evitar-ne la realització. Aquestes recomanacions són consensuades i avalades per les societats científiques, els professionals sanitaris, els pacients i l’AQuAS.
"Els nens i nenes amb faringitis no haurien de prendre antibiòtics en infeccions que no estiguin causades per bacteri". RECOMANACIÓ ESSENCIAL per a pacients. Essencial és una iniciativa de l’Agència de Qualitat i Avaluació Sanitàries (AQuAS) del Departament de Salut de la Generalitat de Catalunya que identifica pràctiques clíniques de poc valor i promou recomanacions per tal d’evitar-ne la realització. Aquestes recomanacions són consensuades i avalades per les societats científiques, els professionals
sanitaris, els pacients i l’AQuAS.
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Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
HOT NEW PRODUCT! BIG SALES FAST SHIPPING NOW FROM CHINA!! EU KU DB BK substit...GL Anaacs
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Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
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Shared Decision Making in Health in Catalonia
1. Moharra M1; Pons JMV; Bañeres J2; Fontcuberta JM2; Costa N3
1.Agency for Healthcare Quality and Assessment of Catalonia; 2. Fundació Avedis Donabedian; 3.Catalan
Patient Advisory Council
Shared Decision Making in Catalonia:
a new step forward in improving decision making process
2. 2
Shared Decision Making
At least two participants: physicians and patients are involved
Both parties share information
(evidence based information about treatment options, cons and pros,
patient preferences and values.)
An agreement is reached on the treatment to implement
3. 3
Background
Cultural change
(physician-patient relationship)
Internet use and new ICT
(ensure quality of information)
Patients’ right and patient autonomy
Improving health literacy and numeracy
4. 4
Patient Decision Aids (DA)
Provide information about the available options on diagnosis
(screening) or treatment, benefit/risk, uncertainty.
Background
5. 5
Main Decision Aid Developers
Organisation Country
Ottawa Hospital Research Institute (OHRI)
Patient Decision Aids
Canada
Informed Medical Decisions Foundation
Shared Decision Making Program
USA
Agency for Healthcare Research and Quality
Effective Healthcare Program
USA
Mayo Clinic
Shared Decision Making National Resource Center
USA
The Health Foundation
Person-centred care resource center
UK
Servicio Canario de Salud
Participa y decide sobre tu salud
Spain
Background
6. 6
Development process criteria (reports readability levels,
reports update, acceptable to users)
Content criteria (list of options, benefits/advantages,
compares probabilities)
Effectiveness criteria (evidence that it helps people know
about different options…)
Background
7. 7
Agency for Healthcare Quality and Assessment of Catalonia
Catalan Patient Advisory Council
Collaboration:
• Patient and family associations
• Scientific Societies
Objective
7
• To provide patients with the best scientific evidence through
information (health condition, appropriate treatment options,
test on patients’ values) for discussing with their doctors
reasonable treatment and decision options.
8. 8
Results
8
• Treatment options
• Pros and cons of each
option
• Life style conditions
• Patient Preference test
• FAQ
Advanced Chronic
kidney disease
Surgery Radiation
BraquitherapyActive surveillance
Peritoneal dyalisis Hemodyalisis
Localized prostate cancer
Transplantation
9. 9
Discussion
9
•To improve communication between healthcare
professionals and patients
• To make patients less passive in decision making
process
•To reduce overuse
•To improve adherence to the treatment.
Patient Decision Aids may help...
Stacey D et al; Decision aids for people facing health treatment or screening decisions (Review) 2014 The
Cochrane Collaboration.
10. 10
Discussion
10
• Lack of knowledge about supporting patients
making health decisions
•Time constraints
•Lack of resources
•Training of healthcare professionals
Challenges for the future...
11. 11
Conclusions
11
Both Decision Aids will help to ensure that patients start being
involved in the treatment decision making with their doctors and
this might have an impact in the future in decreasing overuse or
increasing patient empowerment and satisfaction.
These DAs not only emphasize the availability of multiple
treatment options and the role of the patient in this process but
the added value is that they take into account patients’
preferences, values and opinions.
12. 12
Conclusions
12
There are however still some challenges to cope with in the
future such as the evaluation of this new DAs and the main
barriers and facilitators to overcome for its successful
implementation in the decision making process.
13. 13
Next steps
Healthcare professionals
Scientific societies
Research groups
2015
• Breast cancer
• Carpal tunnel
• Knee replacement surgery
• Diabetes
• C-section
• Hip replacement surgery
• Decisions at the end of life
2016
13