For my 400 level class to my undergraduate degree, we were separated into research groups and choose a topic. The topic we researched all semester was sexual dysfunction. This topic incorporated prostate cancer and menopause. The following slide show is the result and conclusions of several papers read by our group.
We were able to conclude with an exercise prescription to slow the progression of prostate cancer. including: mode, duration, frequency, and intensity. Through collaborative analysis of other studies, we were also able to conclude sexual recommendations to slow the disease and lower risk.
Enjoy.
Holly Thacker, Update on: Menopause, Hormone Therapy, Sex, Politics, and the ...Cleveland HeartLab, Inc.
This document provides an overview and summary of a presentation on menopause, hormone therapy, cardiovascular health, and women's health issues. It discusses the aftermath of the Women's Health Initiative study 12 years later, compares risks of hormone therapy to other medications, and examines risk/benefit ratios of hormone therapy for cardiovascular disease. It also addresses politics surrounding women's health issues and "war on women" narratives related to hormone therapy. The presentation aims to provide an updated perspective on these issues based on newer research findings.
This document provides information on menopause, including its definition, causes, symptoms, effects, diagnosis, and treatment options. It can be summarized as follows:
1. Menopause is defined as the permanent cessation of menstruation resulting from loss of ovarian follicles, with an average age of onset being 51 years. It can occur prematurely before age 45 due to various causes.
2. Short term symptoms include hot flashes, mood swings, sleep problems, and vaginal dryness. Long term risks include osteoporosis and increased risk of heart disease.
3. Diagnosis is based on cessation of periods for 12 months and elevated FSH levels. Treatment options include hormone
This document defines and discusses andropause (also known as male menopause), including its definition, symptoms, epidemiology, pathophysiology, effects of testosterone deficiency, monitoring and risks/benefits of testosterone replacement therapy. Some key points are: andropause is characterized by declining testosterone levels and affects quality of life; symptoms include reduced energy, libido and erectile dysfunction; prevalence increases with age, with 20% of men over 60 and 50% of men over 75 having low testosterone; testosterone replacement can improve symptoms in men with very low levels if administered carefully under medical supervision due to risks like prostate issues.
This document discusses menopause and the options for hormone replacement therapy (HRT). It covers the physiology of menopause, effects of declining estrogen levels, and risks like hot flashes, bone loss, and cardiovascular disease. It presents both benefits and risks of HRT, as well as non-hormonal options and lifestyle interventions like diet, exercise and supplements that can help manage menopause symptoms and health risks. The key decision is choosing treatments that improve quality of life based on each woman's individual symptoms, risk factors and medical history.
Tibolone is an effective treatment for managing menopause symptoms. It provides relief from vasomotor symptoms like hot flashes and night sweats comparable to conventional hormone therapy. It also improves urogenital symptoms and has benefits for bone and sexual health. Tibolone has a lower risk of side effects like vaginal bleeding and breast pain compared to estrogen plus progestin therapy. It does not increase the risk of endometrial hyperplasia or breast cancer. Tibolone is a good alternative to conventional hormone therapy for managing menopause symptoms with fewer side effects.
This document discusses menopause and andropause (the male equivalent). It defines menopause as when a woman's monthly menstrual cycle ends permanently, usually occurring around age 50. Andropause is a slow decline in testosterone production in men with age. Both result in lower sex hormone levels and can cause symptoms. The document reviews hormone production and roles, common symptoms, and natural treatment options focused on supporting the body's own hormone balance rather than external replacement.
This document discusses menopause and hormone replacement therapy. It begins by defining menopause as the permanent stoppage of menstruation due to declining ovarian function. It then discusses the stages of menopause including perimenopause and the changes in hormones like FSH and estrogen that occur. The document notes that menopause is a natural process but can cause both short term symptoms and long term health issues if estrogen is not replaced. It evaluates the risks and benefits of different treatment options for menopause including lifestyle changes, alternative therapies, medical treatments, and hormone replacement therapy.
Menopause is defined as the absence of menstrual periods for at least 12 months. It typically occurs between ages 45-55, though can happen as early as age 30. Menopause is caused by a loss of responsiveness of the ovaries to hormones like FSH and LH, causing lower estrogen and progesterone levels. Common symptoms include irregular periods, hot flashes, mood changes, and increased risk for osteoporosis and heart disease. Treatment options include hormone replacement therapy, antidepressants, lifestyle changes, and lubricants to relieve vaginal dryness.
Holly Thacker, Update on: Menopause, Hormone Therapy, Sex, Politics, and the ...Cleveland HeartLab, Inc.
This document provides an overview and summary of a presentation on menopause, hormone therapy, cardiovascular health, and women's health issues. It discusses the aftermath of the Women's Health Initiative study 12 years later, compares risks of hormone therapy to other medications, and examines risk/benefit ratios of hormone therapy for cardiovascular disease. It also addresses politics surrounding women's health issues and "war on women" narratives related to hormone therapy. The presentation aims to provide an updated perspective on these issues based on newer research findings.
This document provides information on menopause, including its definition, causes, symptoms, effects, diagnosis, and treatment options. It can be summarized as follows:
1. Menopause is defined as the permanent cessation of menstruation resulting from loss of ovarian follicles, with an average age of onset being 51 years. It can occur prematurely before age 45 due to various causes.
2. Short term symptoms include hot flashes, mood swings, sleep problems, and vaginal dryness. Long term risks include osteoporosis and increased risk of heart disease.
3. Diagnosis is based on cessation of periods for 12 months and elevated FSH levels. Treatment options include hormone
This document defines and discusses andropause (also known as male menopause), including its definition, symptoms, epidemiology, pathophysiology, effects of testosterone deficiency, monitoring and risks/benefits of testosterone replacement therapy. Some key points are: andropause is characterized by declining testosterone levels and affects quality of life; symptoms include reduced energy, libido and erectile dysfunction; prevalence increases with age, with 20% of men over 60 and 50% of men over 75 having low testosterone; testosterone replacement can improve symptoms in men with very low levels if administered carefully under medical supervision due to risks like prostate issues.
This document discusses menopause and the options for hormone replacement therapy (HRT). It covers the physiology of menopause, effects of declining estrogen levels, and risks like hot flashes, bone loss, and cardiovascular disease. It presents both benefits and risks of HRT, as well as non-hormonal options and lifestyle interventions like diet, exercise and supplements that can help manage menopause symptoms and health risks. The key decision is choosing treatments that improve quality of life based on each woman's individual symptoms, risk factors and medical history.
Tibolone is an effective treatment for managing menopause symptoms. It provides relief from vasomotor symptoms like hot flashes and night sweats comparable to conventional hormone therapy. It also improves urogenital symptoms and has benefits for bone and sexual health. Tibolone has a lower risk of side effects like vaginal bleeding and breast pain compared to estrogen plus progestin therapy. It does not increase the risk of endometrial hyperplasia or breast cancer. Tibolone is a good alternative to conventional hormone therapy for managing menopause symptoms with fewer side effects.
This document discusses menopause and andropause (the male equivalent). It defines menopause as when a woman's monthly menstrual cycle ends permanently, usually occurring around age 50. Andropause is a slow decline in testosterone production in men with age. Both result in lower sex hormone levels and can cause symptoms. The document reviews hormone production and roles, common symptoms, and natural treatment options focused on supporting the body's own hormone balance rather than external replacement.
This document discusses menopause and hormone replacement therapy. It begins by defining menopause as the permanent stoppage of menstruation due to declining ovarian function. It then discusses the stages of menopause including perimenopause and the changes in hormones like FSH and estrogen that occur. The document notes that menopause is a natural process but can cause both short term symptoms and long term health issues if estrogen is not replaced. It evaluates the risks and benefits of different treatment options for menopause including lifestyle changes, alternative therapies, medical treatments, and hormone replacement therapy.
Menopause is defined as the absence of menstrual periods for at least 12 months. It typically occurs between ages 45-55, though can happen as early as age 30. Menopause is caused by a loss of responsiveness of the ovaries to hormones like FSH and LH, causing lower estrogen and progesterone levels. Common symptoms include irregular periods, hot flashes, mood changes, and increased risk for osteoporosis and heart disease. Treatment options include hormone replacement therapy, antidepressants, lifestyle changes, and lubricants to relieve vaginal dryness.
Andropause, also known as male menopause, is the gradual decline in testosterone levels that occurs in men as they age. Unlike female menopause which is sudden, andropause is a slow process resulting in more subtle symptoms. Low testosterone can negatively impact many organ systems and quality of life. Treatment options include lifestyle changes as well as hormone replacement therapy administered through oral, injectable, or transdermal methods. However, testosterone therapy may increase risks for certain health conditions like sleep apnea and prostate issues.
Hormone replacement therapy outlines the definitions, physiological changes, symptoms, diagnosis, and treatment options associated with menopause. It discusses indications and contraindications for HRT and provides details on different HRT regimens. Side effects of estrogen and progestogen are listed. Large studies on HRT like the Heart and Estrogen/Progestin Replacement Study and the Women's Health Initiative Study are summarized, noting their findings on risks and benefits of HRT use.
This document discusses menopause and hormone therapy. It covers topics like the definition of menopause, common symptoms during menopause, medical intervention guidelines, and safety and benefits of hormone therapy. It provides information on different hormone therapy options, guidelines from medical societies on hormone therapy use, and the effects of hormone therapy on conditions like osteoporosis and cardiovascular disease.
2014 :Updated information on Hormone Replacement TherapyHesham Al-Inany
This document provides an overview of hormone replacement therapy (HRT) and discusses its risks and benefits. It summarizes that:
1) HRT remains the most effective therapy for relieving menopausal symptoms like hot flashes, but comes with some health risks.
2) The risks of HRT, like breast cancer and cardiovascular disease, depend on factors like a woman's age, time since menopause, and type of HRT regimen used. Younger postmenopausal women who use HRT have a reduced risk of cardiovascular disease.
3) Different progestogen components and routes of administration in HRT regimens can impact health risks like thromboembolism and stroke differently.
Mrs. A presented to the menopausal clinic distressed about her symptoms of menopause. She was experiencing hot flashes throughout the day and night, depression, irritability, and poor sleep. Her children had grown and left home, leaving her feeling lonely. The document then provides information on menopause, its stages and symptoms, and treatment options including hormone replacement therapy and lifestyle modifications.
This document summarizes options for treating menopause symptoms including hormone replacement therapy and bioidentical hormones. It discusses formulations, dosages, administration routes, side effects and risks of both approaches. Specifically, it notes that bioidentical hormones have an identical chemical structure to human hormones, while synthetic hormones only mimic some functions. Transdermal delivery and lower doses of bioidentical hormones may provide a more favorable risk-benefit profile.
Key points in prescription writing in menopause, Dr. Sharda Jain, Dr. Jyoti A...Lifecare Centre
1. Menopause is caused by the depletion of ovarian follicles leading to a decline in estrogen levels, and can also result from surgical removal of the ovaries and uterus.
2. Estrogen plays an important role in many bodily functions beyond reproduction, including brain and psychological health, temperature regulation, bone and heart health, and more.
3. Hormone replacement therapy is often used to treat discomforting menopause symptoms, but its use requires consideration of risks like increased chances of blood clots, stroke, and certain cancers. Alternative treatments include progesterone, gabapentin, SSRIs, and herbal remedies.
This document provides an overview of menopause, including definitions, physiological changes, diagnosis, and treatments. It discusses the average age of menopause and influential factors. It defines menopause, premature ovarian failure, and the menopausal transition period. It then covers changes to the hypothalamus-pituitary-ovarian axis, ovaries, endometrium, central thermoregulation, and other areas. It provides details on evaluating abnormal uterine bleeding and discusses treatment options like hormone replacement therapy, antidepressants, clonidine, gabapentin, and complementary therapies.
I don't know anything about Hormone Replacement Therapy before I take this topic. As I know something, I like to share my idea in the way of powerpoint to all us.
This document summarizes the current research on hormone replacement therapy (HRT) for menopausal women. It finds that while HRT can help reduce osteoporosis and improve quality of life, it also increases risks of cancer, blood clots, and heart disease. Large clinical trials found no cardiovascular benefit to HRT and higher risks with combined estrogen-progestin therapy. More research is still needed but HRT should not be seen as an anti-aging treatment given lifestyle factors have a major influence on women's health outcomes. Non-estrogen therapies may be better options for osteoporosis prevention.
Hormone replacement therapy (HRT) involves administering hormones to supplement a lack of natural hormones or substitute other hormones. It is primarily used as a medical treatment for post-menopausal symptoms but can also treat hormone deficiencies in men. There are several types of HRT including testosterone replacement therapy, transgender hormone therapy, and menopausal hormone therapy. Menopausal HRT provides benefits like relieving vasomotor symptoms and protects bone and cardiovascular health but also carries risks like increased breast cancer risk.
This document summarizes an informational session on hormone therapy given by Dr. Ann Stanger. It discusses the symptoms of perimenopause and menopause. It reviews findings from the Women's Health Initiative study on hormone therapy and notes limitations. It also discusses testing and treating hormone imbalances using bioidentical hormones like estradiol, progesterone, and testosterone through various administration routes.
1. The document summarizes two patient cases involving menopause and hormone replacement therapy (HRT). The first case is a 52-year-old woman experiencing menopausal symptoms who is continuing HRT. The second case is a 51-year-old woman with Sheehan's syndrome who is being weaned off HRT.
2. The document then reviews recommendations and guidelines for HRT use, including that it remains the most effective treatment for vasomotor symptoms. It discusses the immediate effects of HRT on various systems and considerations for progestogen use.
3. Alternative treatments to HRT are also mentioned, including SSRIs, venlafaxine, and phytoestrog
The document discusses andropause, also known as late-onset hypogonadism, which is a common condition characterized by low testosterone levels and associated symptoms in aging men. It defines andropause and discusses the diagnosis of late-onset hypogonadism based on symptoms and low testosterone levels. Potential benefits of testosterone replacement therapy are also summarized, including improved body composition, increased muscle and bone mass, and enhanced sexual function. While testosterone therapy shows potential benefits, the document notes that further large clinical trials are still needed to fully evaluate risks and complex interactions with aging.
The document discusses the health effects of menopause and the potential benefits and risks of menopausal hormone replacement therapy (HRT). It summarizes several studies that have examined the link between HRT and various cancers. The risks of HRT include a small increased risk of breast cancer with long-term use (10+ years) and an increased risk of endometrial cancer, especially with long-term or high-dose use without progestogen. However, short-term HRT appears to have little to no increased cancer risk. The document concludes that the decision to use HRT requires weighing its potential benefits against the individual woman's health risks.
This document summarizes evidence-based guidelines on hormone replacement therapy. It discusses that HRT can effectively treat hot flashes and vaginal atrophy but may increase risks of breast cancer, heart disease, and blood clots if used long-term. Larger studies like the Women's Health Initiative found these health risks outweighed benefits for chronic disease prevention. Recommendations are that HRT only be used at lowest effective doses for shortest time to treat menopausal symptoms.
This document summarizes evidence-based guidelines on hormone replacement therapy. It discusses that HRT can effectively treat hot flashes and vaginal atrophy but may increase risks of breast cancer, heart disease, and blood clots if used long-term. Larger studies like the Women's Health Initiative found these health risks outweighed benefits for chronic disease prevention. Recommendations are that HRT only be used at lowest effective doses for shortest time to treat menopausal symptoms.
This document summarizes menopause and perimenopause, including common symptoms, hormone replacement therapy options, lifestyle changes, and alternative treatments. It defines menopause as when a woman's ovaries stop producing eggs and menstruation stops. Perimenopause is the transition period before menopause, when periods become irregular. Common symptoms include hot flashes, night sweats, sleep problems, and mood changes. Hormone replacement therapy can help relieve symptoms but also has risks if used long term or in large amounts. Lifestyle changes like diet, exercise, and stress reduction are recommended to help reduce symptoms without hormones.
- The document discusses an integrated approach to cancer prevention and treatment through lifestyle changes.
- It presents a model showing how lifestyle factors like nutrition, exercise, stress, and social support can affect cancer development over many years and influence whether cancer progresses or not.
- Evidence from studies on nutrition, exercise, stress management, and social support suggest that adopting a healthy lifestyle may reduce cancer risk and slow cancer progression. The Prostate Cancer Lifestyle Trial found significant benefits of lifestyle changes for men with early-stage prostate cancer.
Andropause, also known as male menopause, is the gradual decline in testosterone levels that occurs in men as they age. Unlike female menopause which is sudden, andropause is a slow process resulting in more subtle symptoms. Low testosterone can negatively impact many organ systems and quality of life. Treatment options include lifestyle changes as well as hormone replacement therapy administered through oral, injectable, or transdermal methods. However, testosterone therapy may increase risks for certain health conditions like sleep apnea and prostate issues.
Hormone replacement therapy outlines the definitions, physiological changes, symptoms, diagnosis, and treatment options associated with menopause. It discusses indications and contraindications for HRT and provides details on different HRT regimens. Side effects of estrogen and progestogen are listed. Large studies on HRT like the Heart and Estrogen/Progestin Replacement Study and the Women's Health Initiative Study are summarized, noting their findings on risks and benefits of HRT use.
This document discusses menopause and hormone therapy. It covers topics like the definition of menopause, common symptoms during menopause, medical intervention guidelines, and safety and benefits of hormone therapy. It provides information on different hormone therapy options, guidelines from medical societies on hormone therapy use, and the effects of hormone therapy on conditions like osteoporosis and cardiovascular disease.
2014 :Updated information on Hormone Replacement TherapyHesham Al-Inany
This document provides an overview of hormone replacement therapy (HRT) and discusses its risks and benefits. It summarizes that:
1) HRT remains the most effective therapy for relieving menopausal symptoms like hot flashes, but comes with some health risks.
2) The risks of HRT, like breast cancer and cardiovascular disease, depend on factors like a woman's age, time since menopause, and type of HRT regimen used. Younger postmenopausal women who use HRT have a reduced risk of cardiovascular disease.
3) Different progestogen components and routes of administration in HRT regimens can impact health risks like thromboembolism and stroke differently.
Mrs. A presented to the menopausal clinic distressed about her symptoms of menopause. She was experiencing hot flashes throughout the day and night, depression, irritability, and poor sleep. Her children had grown and left home, leaving her feeling lonely. The document then provides information on menopause, its stages and symptoms, and treatment options including hormone replacement therapy and lifestyle modifications.
This document summarizes options for treating menopause symptoms including hormone replacement therapy and bioidentical hormones. It discusses formulations, dosages, administration routes, side effects and risks of both approaches. Specifically, it notes that bioidentical hormones have an identical chemical structure to human hormones, while synthetic hormones only mimic some functions. Transdermal delivery and lower doses of bioidentical hormones may provide a more favorable risk-benefit profile.
Key points in prescription writing in menopause, Dr. Sharda Jain, Dr. Jyoti A...Lifecare Centre
1. Menopause is caused by the depletion of ovarian follicles leading to a decline in estrogen levels, and can also result from surgical removal of the ovaries and uterus.
2. Estrogen plays an important role in many bodily functions beyond reproduction, including brain and psychological health, temperature regulation, bone and heart health, and more.
3. Hormone replacement therapy is often used to treat discomforting menopause symptoms, but its use requires consideration of risks like increased chances of blood clots, stroke, and certain cancers. Alternative treatments include progesterone, gabapentin, SSRIs, and herbal remedies.
This document provides an overview of menopause, including definitions, physiological changes, diagnosis, and treatments. It discusses the average age of menopause and influential factors. It defines menopause, premature ovarian failure, and the menopausal transition period. It then covers changes to the hypothalamus-pituitary-ovarian axis, ovaries, endometrium, central thermoregulation, and other areas. It provides details on evaluating abnormal uterine bleeding and discusses treatment options like hormone replacement therapy, antidepressants, clonidine, gabapentin, and complementary therapies.
I don't know anything about Hormone Replacement Therapy before I take this topic. As I know something, I like to share my idea in the way of powerpoint to all us.
This document summarizes the current research on hormone replacement therapy (HRT) for menopausal women. It finds that while HRT can help reduce osteoporosis and improve quality of life, it also increases risks of cancer, blood clots, and heart disease. Large clinical trials found no cardiovascular benefit to HRT and higher risks with combined estrogen-progestin therapy. More research is still needed but HRT should not be seen as an anti-aging treatment given lifestyle factors have a major influence on women's health outcomes. Non-estrogen therapies may be better options for osteoporosis prevention.
Hormone replacement therapy (HRT) involves administering hormones to supplement a lack of natural hormones or substitute other hormones. It is primarily used as a medical treatment for post-menopausal symptoms but can also treat hormone deficiencies in men. There are several types of HRT including testosterone replacement therapy, transgender hormone therapy, and menopausal hormone therapy. Menopausal HRT provides benefits like relieving vasomotor symptoms and protects bone and cardiovascular health but also carries risks like increased breast cancer risk.
This document summarizes an informational session on hormone therapy given by Dr. Ann Stanger. It discusses the symptoms of perimenopause and menopause. It reviews findings from the Women's Health Initiative study on hormone therapy and notes limitations. It also discusses testing and treating hormone imbalances using bioidentical hormones like estradiol, progesterone, and testosterone through various administration routes.
1. The document summarizes two patient cases involving menopause and hormone replacement therapy (HRT). The first case is a 52-year-old woman experiencing menopausal symptoms who is continuing HRT. The second case is a 51-year-old woman with Sheehan's syndrome who is being weaned off HRT.
2. The document then reviews recommendations and guidelines for HRT use, including that it remains the most effective treatment for vasomotor symptoms. It discusses the immediate effects of HRT on various systems and considerations for progestogen use.
3. Alternative treatments to HRT are also mentioned, including SSRIs, venlafaxine, and phytoestrog
The document discusses andropause, also known as late-onset hypogonadism, which is a common condition characterized by low testosterone levels and associated symptoms in aging men. It defines andropause and discusses the diagnosis of late-onset hypogonadism based on symptoms and low testosterone levels. Potential benefits of testosterone replacement therapy are also summarized, including improved body composition, increased muscle and bone mass, and enhanced sexual function. While testosterone therapy shows potential benefits, the document notes that further large clinical trials are still needed to fully evaluate risks and complex interactions with aging.
The document discusses the health effects of menopause and the potential benefits and risks of menopausal hormone replacement therapy (HRT). It summarizes several studies that have examined the link between HRT and various cancers. The risks of HRT include a small increased risk of breast cancer with long-term use (10+ years) and an increased risk of endometrial cancer, especially with long-term or high-dose use without progestogen. However, short-term HRT appears to have little to no increased cancer risk. The document concludes that the decision to use HRT requires weighing its potential benefits against the individual woman's health risks.
This document summarizes evidence-based guidelines on hormone replacement therapy. It discusses that HRT can effectively treat hot flashes and vaginal atrophy but may increase risks of breast cancer, heart disease, and blood clots if used long-term. Larger studies like the Women's Health Initiative found these health risks outweighed benefits for chronic disease prevention. Recommendations are that HRT only be used at lowest effective doses for shortest time to treat menopausal symptoms.
This document summarizes evidence-based guidelines on hormone replacement therapy. It discusses that HRT can effectively treat hot flashes and vaginal atrophy but may increase risks of breast cancer, heart disease, and blood clots if used long-term. Larger studies like the Women's Health Initiative found these health risks outweighed benefits for chronic disease prevention. Recommendations are that HRT only be used at lowest effective doses for shortest time to treat menopausal symptoms.
This document summarizes menopause and perimenopause, including common symptoms, hormone replacement therapy options, lifestyle changes, and alternative treatments. It defines menopause as when a woman's ovaries stop producing eggs and menstruation stops. Perimenopause is the transition period before menopause, when periods become irregular. Common symptoms include hot flashes, night sweats, sleep problems, and mood changes. Hormone replacement therapy can help relieve symptoms but also has risks if used long term or in large amounts. Lifestyle changes like diet, exercise, and stress reduction are recommended to help reduce symptoms without hormones.
- The document discusses an integrated approach to cancer prevention and treatment through lifestyle changes.
- It presents a model showing how lifestyle factors like nutrition, exercise, stress, and social support can affect cancer development over many years and influence whether cancer progresses or not.
- Evidence from studies on nutrition, exercise, stress management, and social support suggest that adopting a healthy lifestyle may reduce cancer risk and slow cancer progression. The Prostate Cancer Lifestyle Trial found significant benefits of lifestyle changes for men with early-stage prostate cancer.
This document summarizes information on prostate cancer, including risk factors, diagnosis, and treatment options. It also discusses the potential role of nutrition in prostate cancer. Key points include:
- Prostate cancer is the most common non-skin cancer in men and the second leading cause of cancer death. Risk increases with age and is higher in African-American men and those with a family history.
- Diagnosis involves a digital rectal exam, PSA test, biopsy. Treatment depends on cancer severity and includes surveillance, surgery, radiation, and hormone therapy.
- Nutritional factors like a low-fat, plant-based diet high in fiber and omega-3 fatty acids may reduce prostate cancer risk and slow progression by
Health and healing for body and mind - 25 July 2016BreaCan
Assoc. Prof. Craig Hassed is a GP, teacher and a leader in the field of mind-body medicine. He presents on the importance of lifestyle, mindfulness and integrating mind and body in the management of a cancer diagnosis and treatment. 25 July 2016 at BreaCan in Melbourne, Australia.
Exercise Is Medicine: How a Medical Fitness Center Differs from a Health ClubMercy Medical Center
During his presentation on 2/25/14, Eldon Jones, director of health & fitness at Mercy Medical Center in Canton, Ohio, explains how exercise often is as effective as medication in treating certain chronic serious health conditions, including heart disease, diabetes and more.
Eldon also covered how a medical fitness center differs from a tradition gym or health club.
Other topics covered in the presentaton:
* The importance of prescribing exercise
* US Physical Activity Guidelines
* Cardiac rehabilitation and how it works
* Components of ExRx for risk factor reduction
* FITT principle
* Stages of conditioning
* Strength training
The Women's Health Initiative (WHI) was a 15-year study from 1991-2010 that examined the effects of postmenopausal hormone therapy (HT) and lifestyle interventions on health outcomes in postmenopausal women. The WHI hormone therapy trials found that estrogen plus progestin therapy modestly increased risks of heart disease, stroke, blood clots and breast cancer. Estrogen-alone therapy increased risks of stroke and blood clots but did not change heart disease risk. Subsequent research has found that risks may depend on factors like age at start of therapy, duration of use, and type of progestin used. Current recommendations are to use the lowest effective dose of HT for the shortest time to treat
The Women's Health Initiative (WHI) was a 15-year study from 1991-2010 that examined the effects of postmenopausal hormone therapy (HT) and lifestyle interventions on health outcomes in postmenopausal women. The WHI hormone therapy trials found that estrogen plus progestin therapy increased risks of heart disease, stroke, blood clots and breast cancer. Estrogen-alone therapy increased risks of stroke and blood clots but did not change heart disease risk. Subsequent research has found that risks may depend on factors like age at start of therapy, duration of use, and type of progestin used. Current recommendations are to use the lowest effective dose of HT for the shortest time to treat menop
The Women's Health Initiative (WHI) was a 15-year study from 1991-2010 that examined the effects of postmenopausal hormone therapy (HT) and lifestyle interventions on health outcomes in postmenopausal women. The WHI hormone therapy trials found that estrogen plus progestin therapy modestly increased risks of heart disease, stroke, blood clots and breast cancer. Estrogen-alone therapy increased risks of stroke and blood clots but did not change heart disease risk. Subsequent research has found that risks may depend on factors like age at start of therapy, duration of use, and type of progestin used. Current recommendations are to use the lowest effective dose of HT for the shortest time to treat
The Women's Health Initiative (WHI) was a 15-year study from 1991-2010 that examined the effects of postmenopausal hormone therapy (HT) and lifestyle interventions on health outcomes in postmenopausal women. The WHI hormone therapy trials found that estrogen plus progestin therapy modestly increased risks of heart disease, stroke, blood clots and breast cancer. Estrogen-alone therapy increased risks of stroke and blood clots but did not change heart disease risk. Subsequent research has found that risks may depend on factors like age at start of therapy, duration of use, and type of progestin used. Current recommendations are to use the lowest effective dose of HT for the shortest time to treat
Myths and legacy of exercisemedicine in chronic diseasesAnn Gates
London Sports and Exercise Medicine Presentation.
December 2015.
Copyright Exercise Works Ltd. All rights reserved.
Contact ann@exercise-works.org for permissions.
Tips on how to preven prostate cancer(1)Aaron Saund
The document discusses the controversy around PSA tests for prostate cancer screening. It notes that a US government panel recommends against PSA tests for healthy men, as studies show PSA tests can lead to overdiagnosis and unnecessary treatments without clear benefits. The document then outlines several dietary and lifestyle changes that may help prevent prostate cancer or slow its progression, including eating fatty fish and tomatoes, cruciferous vegetables, following a Mediterranean diet, drinking green tea, taking selenium supplements, getting vitamin D from sun exposure, and staying physically active.
Benefits of Physical Activities (PA) in Cancer SurvivorsRajat Chauhan
On 4th March 2012, I had the privelege of talking at Asian Breast Cancer Conference. But I wasn't planning on going there and be a yes man.
I took the oncology fraternity to task. If they have known for a long time that exercise and physical activity reduces cancer risk by 25-50% and side effects in survivors from inactivity is as bad as disease itself, then why don't they talk and promote more about it. Only a quarter bring up exercise to their patients. I was looking to get a reaction, whether it be a shoe thrown at me or saying, wow... Let's work together on this... But the audience was very sedated... courtesy the pharmaceutical industry that sponsors conferences like these. There was no response. I finished my talk by saying "my role model is Lance Armstrong, a man who did amazing things in world of sports after he was diagnosed, treated and then survived cancer."
Enjoy the presentation.
Screening for prostate cancer remains controversial due to the high risk of overdiagnosis and overtreatment. While screening can find early-stage cancers, most prostate cancers grow slowly and will not cause harm. Screening often leads to unnecessary biopsies, treatments and side effects like impotence and incontinence without clear benefits. Younger, low-risk men are unlikely to benefit from PSA screening, while older men or those at higher risk may benefit if screening finds aggressive cancers early. Active surveillance is often preferred over immediate treatment for low-risk prostate cancers found by screening. Overall, more research is still needed to determine which men would benefit most from prostate cancer screening.
Dr Anna Campbell's keynote speech 'The Importance of Staying Active after a Cancer Diagnosis' at the SCPN's 'Be Active Against Cancer' conference, Tuesday 4th February 2014.
This document discusses prostate cancer and provides information on screening and treatment. It begins by defining the prostate gland and prostate cancer. It then notes that prostate cancer is very common in Nigeria, being the most common cancer in men, and usually presents at a late stage. Screening involves PSA testing and digital rectal exams starting at age 40. If cancer is detected, treatment options depend on the stage and include surgery, radiation, hormone therapy and chemotherapy. Adopting a healthy lifestyle through diet and exercise may help prevent prostate cancer.
The document discusses the long-term side effects of androgen deprivation therapy (ADT) for prostate cancer, including increased risks of osteoporosis, cardiovascular events, sarcopenic obesity, and bone loss. It provides evidence that ADT increases standard cardiovascular risk factors and cardiovascular events. While the effect on cardiovascular mortality is disputed, age and pre-existing conditions are the main risk factors. Exercise and drugs like SERMs may help mitigate side effects, but do not reduce cardiovascular events. Careful management of known risk factors is important when treating with ADT.
Physical Activity and Cancer, a review of innovative current research. Dr. Ni...Irish Cancer Society
Physical activity guidelines exist in many EU countries to reduce cancer risk, though only a minority meet them. Research shows physical activity lowers breast, colon, and endometrial cancer risk by 25-30%, and likely other cancers, through mechanisms like reduced body fat and inflammation. Randomized trials show exercise improves outcomes for breast cancer survivors. More research is needed on optimal dose and type of activity. Ongoing studies examine biological mechanisms and effects on recurrence, survival, and quality of life.
The document discusses testosterone replacement therapy (TRT) and prostate cancer. It notes that while traditional views held that high testosterone led to rapid cancer growth, recent evidence challenges this. Studies found no association between endogenous hormone levels and cancer risk. The saturation model suggests maximal cancer growth occurs at relatively low testosterone levels. Accumulating evidence also links low testosterone with higher-risk cancer features. TRT studies up to 3 years found similar cancer detection rates to screening. While long-term safety data is still needed, available evidence suggests TRT may be considered for selected prostate cancer patients with symptoms of hypogonadism after obtaining informed consent.
Adhd Medication Shortage Uk - trinexpharmacy.comreignlana06
The UK is currently facing a Adhd Medication Shortage Uk, which has left many patients and their families grappling with uncertainty and frustration. ADHD, or Attention Deficit Hyperactivity Disorder, is a chronic condition that requires consistent medication to manage effectively. This shortage has highlighted the critical role these medications play in the daily lives of those affected by ADHD. Contact : +1 (747) 209 – 3649 E-mail : sales@trinexpharmacy.com
Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
Histololgy of Female Reproductive System.pptxAyeshaZaid1
Dive into an in-depth exploration of the histological structure of female reproductive system with this comprehensive lecture. Presented by Dr. Ayesha Irfan, Assistant Professor of Anatomy, this presentation covers the Gross anatomy and functional histology of the female reproductive organs. Ideal for students, educators, and anyone interested in medical science, this lecture provides clear explanations, detailed diagrams, and valuable insights into female reproductive system. Enhance your knowledge and understanding of this essential aspect of human biology.
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NVBDCP.pptx Nation vector borne disease control programSapna Thakur
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ABDOMINAL TRAUMA in pediatrics part one.drhasanrajab
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8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptxHolistified Wellness
We’re talking about Vedic Meditation, a form of meditation that has been around for at least 5,000 years. Back then, the people who lived in the Indus Valley, now known as India and Pakistan, practised meditation as a fundamental part of daily life. This knowledge that has given us yoga and Ayurveda, was known as Veda, hence the name Vedic. And though there are some written records, the practice has been passed down verbally from generation to generation.
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
1. **click on the titles of the studies to be directed to the link
Sexual Dysfunctions
Rielly Moore, Becca Nygaard, Vanessa Hawkes, Natalie
Hughes, Natalie Wehrhahn
2. Prostate Cancer (PCa)
● One in seven men will be diagnosed with Prostate Cancer
● CANCER RANKS SECOND only to heart disease as the leading cause of
death in North America
● Healthy prostate is the size of a walnut
● Black people are at increased risk
● 20-29 Low/High Risk, 30-49 Medium Risk, 50-69 High Risk
● Higher risk if father or brother is diagnosed (2,5 times)
3. Introduction to
Recommendations
❏ Introductions
❏ Physical Activity
-Exercise
-Frequency
-Duration
-Intensity
-Mode
-Sexual Activity
-Frequency
-Treatment
-Prevention
-Hormones
-Correlation with Women and Menopause
❏ Recommendations
❏ Conclusion
4.
5. Exercise for PCa:
A Prospective Study of Physical Activity and Incident and Fatal Prostate
Cancer:
-This study concluded that men >65 years old with vigorous exercise had a
70% reduction in developing Advanced Prostate Cancer, and slowing the
progression of PCa with 30 MET hours/week (25 min/day).
Recreational physical activity and risk of prostate cancer: A prospective
population-based study in Norway
-This study concluded that recreational physical activity was not associated
with overall prostate cancer. It does reduce the risk of advanced prostate
cancer, and can protect against prostate cancer death. Men who reported 1
weekly bout of exercise had a 30% lower risk of being diagnosed with
metastatic prostate cancer compared to men who reported no activity.
6. Exercise and PCa
Overall, any kind of exercise, even once a week, will help
with the reduction in developing Advanced PCa, and
slowing the progression of PCa
7. This graph shows how many of the studies read showed significance
in slowing the progression of Prostate Cancer (PCa).
8. Frequency:
A Prospective Study of Physical Activity and Incident and
Fatal Prostate Cancer
**refer to previous slide
Men, ages 65 and older, who participated in 30 MET hours per week would have a 70%
reduction in advanced prostate cancer.
30 MET hours per week equivalent to 3 hours of physical activity.
Men 65 and older should exercise 3 days a week to decrease the risk of being diagnosed
with high-grade, advanced, or fatal PCa
*physically active men may be at lower risk, but it is moderate and not statistically significant
all the time and sometimes only evident in older groups 65 and older and with high levels of
physical activity (vigorous)
9. Frequency cont.
Recreational physical activity and risk of prostate cancer. A
prospective population-based study in Norway (the HUNT
study).
Men who reported working out at least once a week had a 30% lower risk of
metastatic PCa than those men who did not exercise at all [27].
10. Frequency cont.
Exercise Prevents Fatigue and Improves Quality of Life in
Prostate Cancer Patients Under Radiotherapy
randomized study to show fatigue prevention and quality of life improvements from cardiovascular exercise
during radiotherapy; fatigue is the initial manifestation of cancer
21 subjects - ages 68-70
10 control: radiotherapy and no exercise
11 intervention radiotherapy and aerobic exercise 3x a week 8 weeks
*showed statistical improvements in these areas:
❏ Cardiac fitness (P=0.006)
❏ Strength (P=0.000)
❏ Flexibility (P<0.01)
❏ Fatigue (P= 0.001)
❏ Physical well-being (P< .001)
❏ Social well-being (P=.002)
❏ Functional well-being (P=.04)
**statistical significance pvalue of .05 or less
11. Exercise group:
7 of the 12 showed statistical significance (METS, stand-and-sit
test, flexibility, PFS, physical well-being, social well-being, FACT-P)
4 of the 5 other variables had changes in the direction of improvement
(BDI, relationship with the physician, emotional well-being, functional well-being)
Control group: showed significantly worse post-radiotherapy scores
8 out of the 10 (without statistically significant changes)
changed in the direction of poorer performance (METS, stand-and-
sit test, flexibility, BDI, physical well-being, social well-being, relationship with the physician,
functional well-being)
Conclusion:
There is evidence that physical activity influences other
aspects of the cancer experience: decreased fatigue,
improved recovery rate, improved quality of life, and
increasing survival after cancer diagnosis.
12. Frequency Recommendations
3 days a week - decreasing risk and improving symptoms in PCa
patients.
Any type of physical activity no matter the frequency will improve lifestyle for individuals
13. Duration
Physical Activity after Diagnosis and Risk of Prostate Cancer Progression: Data from the Cancer of
the Prostate Strategic Urologic Research Endeavor
physical activity was rated from none - 11h/wk
Main focus was PCa progression defined as death from PCa, bone metastases, biochemical
treatment, or secondary treatment.
It was found the those men who walked 30 MET h/wk or more at a brisk pace had a 57% reduction in
cancer progression when compared with those who did less than 30 MET h/wk. [P=0.03]
Independent of duration
Those who did 30 MET h/wk or more of vigorous exercise had a 37% reduction in cancer progression
when compared to those who didn’t. [Ptrend=0.17]
15. Intensity
A Prospective Study of Physical Activity and Incident and Fatal Prostate
Cancer
The main findings within this study was the significant results in the age group of 65 or older. It was
found the those 65 or older who worked out vigorously saw decreased risk for both non-advanced
and advanced prostate cancer. respective values of P=0.009 and P=0.003.
vigorous define as running, jogging, biking, swimming, tennis, racquetball/squash,
rowing/calisthenics, heavy outdoor work, and weight training
Non-vigorous defined as flights of stairs climbed and walking.
16.
17. Mode
-Aerobic (prolonged and steady) training proved to be beneficial in treatment
of PCa when combining all the studies that mentioned mode of exercise
-Resistance training raises testosterone levels in the body, which was
theorized to lower the risk of PCa. It also reduces fatigue and improves
muscular fitness
-Both have shown significant results
-Many of the studies that we read used the following activities for exercises:
❏ Running
❏ Jogging
❏ Biking
❏ Swimming
❏ Tennis
❏ Racquetball/squash
❏ Rowing/calisthenics
❏ Heavy outdoor work
❏ Weight training
18. Mode
*All studies below showed significance in slowing progression for PCa
19. Treatment and Prevention
Treatment
● Exercise
o Fatigue
o Body Mass
o Bone Density
Prevention
● Exercise
o Hormone levels
● Sexual Activity
o Ejaculation Frequency
o Prostate Cells
o Carcinogens
o STD’s
20. Current treatment available
PCa:
Hormone (androgen deprivation) therapy
reduces the levels of male hormones before they reach cancer cell
testosterone and dihydrotestosterone (DHT)
does not cure and eventually stops working
Surgery - radical prostatectomy, Castration
Radiation therapy
Menopause:
Hormone therapy
Increase Testosterone and Androgens
21. Sexual Activity & Ejaculation
Recommendations
*Recommendations given based off
year lifetime average
**limitation: questionnaires (not completely accurate or
honest)
We can confidently recommend to aim for
over 21 ejaculations per month
22. Sexual Behavior, STDs and Risks for
Prostate Cancer
Risk increase with Gonorrhea and Syphilis 1.6 x higher first time, 3.3 x higher if 3 times
Not using a condom and interactions with prostitutes increases risk
Family History 2 fold increase in risk with father being diagnosed, 5 fold increase in risk if
brother is diagnosed.
23. Ejaculation frequency and subsequent
risk of prostate cancer
Average Lifetime Ejaculation and correlation with risk >21,
decreased risk of developing prostate cancer
From each increase of 3 times a month showed 15% decreased risk in overall
PCa
Organ Confined showed 19% decreased risk with each increase of 3
Advanced cancers 40-49yrs old 4-7
24. Hormones and Prostate
Cancer
❏ Oxford University released a collaborative study in which they analyzed
18 papers discussing Hormones and PCa.
❏ There was no associations found between the risk of PCa and serum
concentrations of:
❏ Testosterone
❏ Calculated free testosterone
❏ Dihydrotestosterone
❏ Dehydroepiandrosterone sulfate
❏ Androstenedione
❏ Androstanediol glucuronide
❏ Estradiol,
❏ Calculated free estradiol
❏ ONE paper out of the 18 DID show a modest inverse relationship
between the serum concentration of sex hormone–binding globulin
(SHBG) and PCa risk (Ptrend = .01)
25. The One SHBG Study:
❏ What they did: Initially a study on Aspirin, blood kits were sent to all
participants with instructions to have their blood drawn and sent back
under proper conditions.
❏ Blood results were as following: estradol, 6.8%; testosterone, 8.7%;
DHT, 5.3%; SHBG, 8.9%; prolactin, 4.4%; and AAG, 7.6%.
❏ By March of 1992, 520 cases of prostate cancer were confirmed among
participants. Only 222 had plasma samples sufficient for analysis.
❏ High levels of plasma testosterone compared with low levels (within the
normal endogenous range were associated with an approximately 2.5-
fold increase in the risk of developing prostate cancer after adjustment
for plasma SHBG and estradiol.
❏ Men with the highest levels of SHBG (Increased levels of SHBG odd
ratios by quartile =1.00, .93, .6, and .46) <P trend.01> had about 50%
lower risk than men with lowest SHBG levels.
26. Increasing Sex Hormone Binding Globulin
through Exercise
Researchers had participants exercise (specifics detailed in study) and were measured at baseline,
3, and 12 months.
Results:
Exercise increased levels of the hormones DHT(dihydrotestosterone) and SHBG, but it had no
effect on the other hormones for men.. Exercisers had significantly increased DHT and SHBG
levels at 3 and 12 months after randomization when compared with participants who did not
exercise.
SHBG increased 14.3% in exercisers versus 5.7% in controls at 3 months (P=0.04); at 12 months,
it remained 8.9% above baseline in exercisers versus 4.0% in controls (P=13).
27. Menopause
● Menopause is what occurs 12 months after a woman’s last menstrual
period which marks the end of their menstrual cycle.
○ 3 phases (pre, peri, post)
● Typically occurs in 45 to 55 age range
● Common symptoms
○ Menstrual irregularity
○ Hot flashes
○ Sleep problems
○ Mood changes
○ Vaginal and bladder problems
○ Changes in sexual function (desire)
○ Loss of bone
28. Physical Activity and Sexuality in
Perimenopausal Women
- This study concluded that there was a significant correlation between
sexual dysfunctions and the general level of physical activity. Best results
were seen at high levels of physical activity. This study measured the
amount of physical activity by looking at;
● Job related physical Activity
● Transportation related physical activity
● Housework related physical activity
● Leisure related physical activity
High Levels of physical activity was defined as:
– vigorous activity on at least three days resulting in at least 25 MET-hours/
week (MET-Metabolic Equivalent of Work),
or
– seven days per week with any combination of walking, moderate-intensity
or vigorous activities representing at least 50 MET-hours/
week;
29. Results
● Because of the lack of research on physical activity and Menopause we
can not confidently recommend a certain amount of physical activity.
The research that was found shows improvements with physical activity
at vigorous levels. But common treatment is Hormone therapy.
30. Correlation: This chart shows the age range and risk level of
prostate cancer which is shown in blue and then in red it shows the
age at which women are going through menopause. Typically women
are going through menopause at the same time that men are at
highest risk for prostate cancer.
Fun Fact: The average age difference between couples is between two to three years
31. Recommendations
● Menopause Treatment
o Moderate to Vigorous
o Hormone Therapy
● PCa Prevention: Sexual Activity
o Ejaculation: >21 times/month
Lifetime avg.
o Older first time sexual
intercourse
o Less number of sexual
partners
● Treatment
● For men older than 65
o Frequency: 3 days/week
o Duration: >29 MET hrs/week
o Intensity: Vigorous
o Mode: Aerobic and
Resistance exercises
● For men <65yrs old
o Frequency: 3 days/week
o Duration: 6 MET hrs/day (60
min/day)
o Intensity: Light to vigorous
o Mode Aerobic and
Resistance Exercise
32. Conclusions
-More ejaculations, when younger (30 and older) decrease risk of developing PCa.
- STD’s and increased number of sexual partners increases risk.
-Males > 65 years old with vigorous exercise have a 70% reduction in developing
Advanced PCa, and slowing the progression of PCa
- Exercise after diagnosis improves quality of life, decreases fatigue, and slows
progression of PCa.
-From all of our studies we can hypothesize that women going through menopause
occurs during a crucial time for men in prevention of prostate cancer, which can be
an increased risk for men
33. Resources
*every title to a study in the powerpoint is a hyperlink to the actual study
mentioned
**link to the excel document with all our references used in this project:
https://docs.google.com/spreadsheets/d/1SIrJ4EfhvD7L74Ltx_g3MvRBqHP3
4JVGDwYy7dYt52I/edit?usp=sharing