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Prof Georgios Sianos, MD, PhD, FESC
Aristotle University
AHEPA University Hospital
Thessaloniki, Greece
A’ Cardiology Department
AHEPA University Hospital
Aristotle University
of Thessaloniki
MICROCATHETERS
NEW
DEVELOPMENTS
Finecross
Corsair
MICROCATHETERS
CORSAIR MICROCATHETER
CORSAIR PRO
TURNPIKE MICROCATHETER
OVERVIEW
OTW catheters with dual-layer coil + braid shaft design
for superior flexibility & torque for delivery over 0.014"
wires
6
Turnpike
superior tracking
in tortuous vessels
Turnpike Spiral
rotational assistance,
trackability
Turnpike Gold
metallic tip for
enhanced advancement
Turnpike LP
low profile & flexible
for extreme tortuosity
CARAVEL MICROCATHETER
FINECROSS MICROCATHETER
FINECROSS MG
0.7mm
0.7mm
MAMBA /MAMBA Flex 135/150
NHANCER PRO X MOSQUITO TIP
TELEPORT AND TELEPORT CONTROL MC
ORBUS NEICH
Straight/FT
Components
Stainless steel braid
enhances deliverability,
flexibility & kink resistance
PTFE inner layer
for superb guidewire
movement & delivery
Tapered distal O.D. = enhanced catheter delivery
through tortuous vessels
VASCULAR SOLUTIONS
TELEFLEX
TIP CONFIGURATIONS
SuperCross Angled Tips
• 130cm & 150cm lengths with 45°, 90° & 120° angles
• XT = extended tip lengthened from 0.65mm to 1.75mm to achieve
more secure cannulation – 130cm & 150cm lengths
TELEFLEX
TELEFLEX
CENTERCROSS AND MULTICROSS
MICRO 14
Jalal S et al, Novel CenterCross and MultiCross devices for the treatment of infrainguinal chronic
total occlusions: initial single-centre experience. EuroIntervention. 2016
HISTORY OF ASAHI CORONARY MICROCATHETERS
ASAHI Corsair Pro
• 2017
ASAHI Caravel
• 2016
ASAHI Corsair
• 2011
ASAHI Corsair Pro XS
• 2020
19
0.88~0.95mm
(2.6~2.9 Fr)
Tip portion (A) Proximal portion (C)Distal portion (B)
A B C
Thinner new SHINKA-Shaft – Cross section
0.38 mm
(0.015 inch)
0.38 ~0.48mm
(0.015~0.019 inch)
0.48mm
(0.018 inch)
0.44 mm
(1.3 Fr)
0.71~0.88mm
(2.1~2.6 Fr)
14 wires
braiding
20
ASAHI CORSAIR PRO XS - KEY FEATURES
Product Tip Entry profile Distal shaft OD Proximal shaft OD
ASAHI Corsair Pro 0.42mm (1.3Fr) 0.87mm (2.6 Fr) 0.93mm (2.8 Fr)
ASAHI Caravel 0.48mm (1.4Fr) 0.62mm (1.9 Fr) 0.85mm (2.6 Fr)
ASAHI Corsair Pro XS 0.44mm (1.3Fr) 0.71mm (2.1 Fr) 0.95mm (2.9 Fr)
Proximal shaft OD
O.D. 0.95 mm (2.9 Fr)
New SHINKA-Shaft
New SHINKA-Shaft
Innovative rotational shaft design increases
device performance in retrograde approach
Distal shaft OD
O.D. 0.71 mm (2.1 Fr)
21
Improved distal tip
• Lower profile and thin tip portion
• Shorter welding between the tip and shaft
• Distal portion with smooth taper
ASAHI Corsair Pro XS
Product Tip Length Tip OD
ASAHI Corsair Pro XS 6.5 mm 0.44mm (1.3 Fr)
High crossability within complex lesions due to the new design of the tip portion.
22
Compatibility
23
Recommended GW : 0.36mm (0.014”)
Minimum GC I.D. 1.05mm (0.041”)
 ASAHI Corsair Pro XS× 2 7Fr, 8Fr GC
 ASAHI Corsair Pro XS + IVUS 8Fr GC
 Trapping ASAHI Corsair Pro XS 6Fr GC
23
Torqueable
Wire support
Pushability and crossability
Torqueable
Flexibility and trackability
Low profile
ASAHI Microcatheters
24
Non torqueable
Low profile
Flexibility and trackability
Confidential to IMDS © IMDS 10/7/2020 NHancer Pro X
NHANCER PRO X UPDATE
SUMMARY
Embedded core wire
comparable to Blimp, ReCross
Double braiding
Tapered shaft design
Improved hydrophilic
coating
High penetration tapered tip
High pushability
1:1 torque response
Gradual increase in flexibility (proximal to
distal)
Lumen integrity
Small inner lumen distally only: trackability
Larger lumen: no resistance with guidewire
Very high lubricity
Small enough + high penetration for crossing
tight lesions, even retrograde
Overview of design Main results
Confidential to IMDS © IMDS 10/7/2020 NHancer Pro X
Pushability
Outer Profile
Flexibility
Inner Lumen Diameter
Push Transfer & 1:1 Torque Response
Double braiding
Embedded
core wire
Tapered shaft design
Improved lubricity
TAILORED DESIGN
Confidential to IMDS © IMDS 10/7/2020 NHancer Pro X
Unique hybrid guidewire-micro catheter capabilities with locked NHancer Pro X torquer
1. Enhanced guidewire penetration force
2. Enhanced catheter lesion crossing with “rotation-lock-cross” technique.
Hybrid shaft locking with the Pro X NX3 series provides superior performance in regard
to guidewire support and micro catheter lesion crossing.
PATENTED HYBRID SHAFT LOCKING
TORQUER “LOCKING” DEVICE
Confidential to IMDS © IMDS 10/7/2020 NHancer Pro X
Confidential to IMDS © IMDS 10/7/2020 NHancer Pro X
Push Transfer & 1:1 Torque Response
Crossability
Flexibility increase
Removable stylet
Core wire
White Tip lumen Ø 0.48mm
Braiding
Blue Stylet lumen Ø 0.48mm
Confidential to IMDS © IMDS 10/7/2020 NHancer Pro X
Versatile Design
Blue Stylet
lumen Ø
0.48mm
Exit port (#3):
White Tip
lumen
White Tip
lumen Ø
0.48mm
Exit port (#2):
Blue Stylet lumen
White Tip
lumen Ø
0.41mm
Tip (#1)
Removable
Stylet
Confidential to IMDS © IMDS 10/7/2020 NHancer Pro X
Versatility
PARALLEL WIRE
REENTRY
SUBINTIMAL LUMEN DECOMRESSION
SINGLE CATHETER – MANY OPTIONS
Confidential to IMDS © IMDS 10/7/2020 NHancer Pro X
Exit ports designed for
Subintimal Guidewire
Redirection
Subintimal Guidewire Redirection
True lumen
Sub-intimal
DUAL LUMEN MICROCATHETERS COMMERCIALLY AVAILABLE
GUIDEZILLA GUIDE EXTENSION
1x1 Braid provides extra back-up support without
over-straightening the vessel. Soft, flexible, and
atraumatic tip designed to minimize the risk of
complications to the vessel
• Coaxial alignment & backup support
• Distal device delivery
• Selective delivery of contrast
Available sizes:
• 5F, 5.5F, 6F, 7F & 8F
• 6F XL (40cm guide extension)
“Child” guide extension delivered through
“mother” guide with rapid exchange construction
Half-pipe to align devices through collar transition
TRAPLINER CATHETER
TELESCOPE GCE
GUIDION RAPID EXCHANGE GUIDE EXTENSION
Proximal shaft change
Current : Round shaft diameter 0.43 (mm)
New : Oval shaft 0.41 mm x 0.50 mm
Distal flex zone
Low density coiling at the distal zone
Transition improvement
Current : Some variation in the steepness of transition
between proximal and distal shaft
New : Completely perfect gradual controlled transition
Proximal end stop color change
Current : White proximal end stop
New : Yellow proximal end stop
IV Generation
TRAPPING DEVICES
© IMDS
Shaft stopper Trapper
Shaft stopper TrapIt
MICROCATHETER CLASSIFICATION
A B C D E
"Big" "Small" Angulated Dual Lumen Plaque modification
Vammou et al. Expert Rev Med Devices. 2019 Apr;16(4):267-273
CORSAIR PRO XS
NX3
CONCLUSION
There is a great evolution in microcatheter
technology both for antegrade and retrograde
approach greatly facilitating the efficacy and
safety of these techniques.
Still microcatheter evolution lacks guidewire
evolution and needs further improvement.
CONCLUSION
There is a great evolution in microcatheter
technology both for antegrade and retrograde
approach greatly facilitating the efficacy and
safety of these techniques.
Still microcatheter evolution lacks guidewire
evolution and needs further improvement.

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Microcatheter Developments and Technologies

  • 1. Prof Georgios Sianos, MD, PhD, FESC Aristotle University AHEPA University Hospital Thessaloniki, Greece A’ Cardiology Department AHEPA University Hospital Aristotle University of Thessaloniki MICROCATHETERS NEW DEVELOPMENTS
  • 6. OVERVIEW OTW catheters with dual-layer coil + braid shaft design for superior flexibility & torque for delivery over 0.014" wires 6 Turnpike superior tracking in tortuous vessels Turnpike Spiral rotational assistance, trackability Turnpike Gold metallic tip for enhanced advancement Turnpike LP low profile & flexible for extreme tortuosity
  • 10. NHANCER PRO X MOSQUITO TIP
  • 11. TELEPORT AND TELEPORT CONTROL MC ORBUS NEICH
  • 12. Straight/FT Components Stainless steel braid enhances deliverability, flexibility & kink resistance PTFE inner layer for superb guidewire movement & delivery Tapered distal O.D. = enhanced catheter delivery through tortuous vessels VASCULAR SOLUTIONS TELEFLEX
  • 13. TIP CONFIGURATIONS SuperCross Angled Tips • 130cm & 150cm lengths with 45°, 90° & 120° angles • XT = extended tip lengthened from 0.65mm to 1.75mm to achieve more secure cannulation – 130cm & 150cm lengths TELEFLEX
  • 15. CENTERCROSS AND MULTICROSS MICRO 14 Jalal S et al, Novel CenterCross and MultiCross devices for the treatment of infrainguinal chronic total occlusions: initial single-centre experience. EuroIntervention. 2016
  • 16. HISTORY OF ASAHI CORONARY MICROCATHETERS ASAHI Corsair Pro • 2017 ASAHI Caravel • 2016 ASAHI Corsair • 2011 ASAHI Corsair Pro XS • 2020 19
  • 17. 0.88~0.95mm (2.6~2.9 Fr) Tip portion (A) Proximal portion (C)Distal portion (B) A B C Thinner new SHINKA-Shaft – Cross section 0.38 mm (0.015 inch) 0.38 ~0.48mm (0.015~0.019 inch) 0.48mm (0.018 inch) 0.44 mm (1.3 Fr) 0.71~0.88mm (2.1~2.6 Fr) 14 wires braiding 20
  • 18. ASAHI CORSAIR PRO XS - KEY FEATURES Product Tip Entry profile Distal shaft OD Proximal shaft OD ASAHI Corsair Pro 0.42mm (1.3Fr) 0.87mm (2.6 Fr) 0.93mm (2.8 Fr) ASAHI Caravel 0.48mm (1.4Fr) 0.62mm (1.9 Fr) 0.85mm (2.6 Fr) ASAHI Corsair Pro XS 0.44mm (1.3Fr) 0.71mm (2.1 Fr) 0.95mm (2.9 Fr) Proximal shaft OD O.D. 0.95 mm (2.9 Fr) New SHINKA-Shaft New SHINKA-Shaft Innovative rotational shaft design increases device performance in retrograde approach Distal shaft OD O.D. 0.71 mm (2.1 Fr) 21
  • 19. Improved distal tip • Lower profile and thin tip portion • Shorter welding between the tip and shaft • Distal portion with smooth taper ASAHI Corsair Pro XS Product Tip Length Tip OD ASAHI Corsair Pro XS 6.5 mm 0.44mm (1.3 Fr) High crossability within complex lesions due to the new design of the tip portion. 22
  • 20. Compatibility 23 Recommended GW : 0.36mm (0.014”) Minimum GC I.D. 1.05mm (0.041”)  ASAHI Corsair Pro XS× 2 7Fr, 8Fr GC  ASAHI Corsair Pro XS + IVUS 8Fr GC  Trapping ASAHI Corsair Pro XS 6Fr GC 23
  • 21. Torqueable Wire support Pushability and crossability Torqueable Flexibility and trackability Low profile ASAHI Microcatheters 24 Non torqueable Low profile Flexibility and trackability
  • 22. Confidential to IMDS © IMDS 10/7/2020 NHancer Pro X NHANCER PRO X UPDATE SUMMARY Embedded core wire comparable to Blimp, ReCross Double braiding Tapered shaft design Improved hydrophilic coating High penetration tapered tip High pushability 1:1 torque response Gradual increase in flexibility (proximal to distal) Lumen integrity Small inner lumen distally only: trackability Larger lumen: no resistance with guidewire Very high lubricity Small enough + high penetration for crossing tight lesions, even retrograde Overview of design Main results
  • 23. Confidential to IMDS © IMDS 10/7/2020 NHancer Pro X Pushability Outer Profile Flexibility Inner Lumen Diameter Push Transfer & 1:1 Torque Response Double braiding Embedded core wire Tapered shaft design Improved lubricity TAILORED DESIGN
  • 24. Confidential to IMDS © IMDS 10/7/2020 NHancer Pro X Unique hybrid guidewire-micro catheter capabilities with locked NHancer Pro X torquer 1. Enhanced guidewire penetration force 2. Enhanced catheter lesion crossing with “rotation-lock-cross” technique. Hybrid shaft locking with the Pro X NX3 series provides superior performance in regard to guidewire support and micro catheter lesion crossing. PATENTED HYBRID SHAFT LOCKING TORQUER “LOCKING” DEVICE
  • 25. Confidential to IMDS © IMDS 10/7/2020 NHancer Pro X
  • 26. Confidential to IMDS © IMDS 10/7/2020 NHancer Pro X Push Transfer & 1:1 Torque Response Crossability Flexibility increase Removable stylet Core wire White Tip lumen Ø 0.48mm Braiding Blue Stylet lumen Ø 0.48mm
  • 27. Confidential to IMDS © IMDS 10/7/2020 NHancer Pro X Versatile Design Blue Stylet lumen Ø 0.48mm Exit port (#3): White Tip lumen White Tip lumen Ø 0.48mm Exit port (#2): Blue Stylet lumen White Tip lumen Ø 0.41mm Tip (#1) Removable Stylet
  • 28. Confidential to IMDS © IMDS 10/7/2020 NHancer Pro X Versatility
  • 29. PARALLEL WIRE REENTRY SUBINTIMAL LUMEN DECOMRESSION SINGLE CATHETER – MANY OPTIONS
  • 30. Confidential to IMDS © IMDS 10/7/2020 NHancer Pro X Exit ports designed for Subintimal Guidewire Redirection Subintimal Guidewire Redirection True lumen Sub-intimal
  • 31. DUAL LUMEN MICROCATHETERS COMMERCIALLY AVAILABLE
  • 32. GUIDEZILLA GUIDE EXTENSION 1x1 Braid provides extra back-up support without over-straightening the vessel. Soft, flexible, and atraumatic tip designed to minimize the risk of complications to the vessel
  • 33. • Coaxial alignment & backup support • Distal device delivery • Selective delivery of contrast Available sizes: • 5F, 5.5F, 6F, 7F & 8F • 6F XL (40cm guide extension) “Child” guide extension delivered through “mother” guide with rapid exchange construction Half-pipe to align devices through collar transition
  • 36. GUIDION RAPID EXCHANGE GUIDE EXTENSION
  • 37. Proximal shaft change Current : Round shaft diameter 0.43 (mm) New : Oval shaft 0.41 mm x 0.50 mm Distal flex zone Low density coiling at the distal zone Transition improvement Current : Some variation in the steepness of transition between proximal and distal shaft New : Completely perfect gradual controlled transition Proximal end stop color change Current : White proximal end stop New : Yellow proximal end stop IV Generation
  • 38. TRAPPING DEVICES © IMDS Shaft stopper Trapper Shaft stopper TrapIt
  • 39. MICROCATHETER CLASSIFICATION A B C D E "Big" "Small" Angulated Dual Lumen Plaque modification Vammou et al. Expert Rev Med Devices. 2019 Apr;16(4):267-273 CORSAIR PRO XS NX3
  • 40. CONCLUSION There is a great evolution in microcatheter technology both for antegrade and retrograde approach greatly facilitating the efficacy and safety of these techniques. Still microcatheter evolution lacks guidewire evolution and needs further improvement.
  • 41. CONCLUSION There is a great evolution in microcatheter technology both for antegrade and retrograde approach greatly facilitating the efficacy and safety of these techniques. Still microcatheter evolution lacks guidewire evolution and needs further improvement.