- Seizures are caused by abnormal electrical discharges in the brain that can be accompanied by various disorders or occur spontaneously. Epilepsy is characterized by recurrent, spontaneous seizures.
- Seizures can be generalized, involving both sides of the brain, or focal, beginning in one area. Common generalized seizures include tonic-clonic, absence, myoclonic, atonic, tonic, and clonic. Focal seizures affect a specific brain region.
- Diagnosis involves the seizure description, EEG, and tests to rule out underlying causes. Treatment includes antiseizure medications and possibly surgery for drug-resistant cases. The goals are preventing injury and status epilepticus while improving quality of
THESE SLIDES ARE PREPAREED TO UNDERSTAND CHILD HEALTH DISORDERS IN EASY WAY Important links- NOTES- https://mynursingstudents.blogspot.com/ youtube channel https://www.youtube.com/c/MYSTUDENTSU... CHANEL PLAYLIST- ANATOMY AND PHYSIOLOGY-https://www.youtube.com/playlist?list=PL93S13oM2gAPM3VTGVUXIeswKJ3XGaD2p COMMUNITY HEALTH NURSING- https://www.youtube.com/playlist?list=PL93S13oM2gAPyslPNdIJoVjiXEDTVEDzs CHILD HEALTH NURSING- https://www.youtube.com/playlist?list=PL93S13oM2gANcslmv0DXg6BWmWN359Gvg FIRST AID- https://www.youtube.com/playlist?list=PL93S13oM2gAMvGqeqH2ZTklzFAZhOrvgP HCM- https://www.youtube.com/playlist?list=PL93S13oM2gAM7mZ1vZhQBHWbdLnLb-cH9 FUNDAMENTALS OF NURSING- https://www.youtube.com/playlist?list=PL93S13oM2gAPFxu78NDLpGPaxEmK1fTao COMMUNICABLE DISEASES- https://www.youtube.com/playlist?list=PL93S13oM2gAOWo4IwNjLU_LCuhRN0ZLeb ENVIRONMENTAL HEALTH- https://www.youtube.com/playlist?list=PL93S13oM2gAPkI6LvfS8Zu1nm6mZi9FK6 MSN- https://www.youtube.com/playlist?list=PL93S13oM2gAOdyoHnDLAoR_o8M6ccqYBm HINDI ONLY- https://www.youtube.com/playlist?list=PL93S13oM2gAN4L-FJ3s_IEXgZCijGUA1A ENGLISH ONLY- https://www.youtube.com/playlist?list=PL93S13oM2gAMYv2a1hFcq4W1nBjTnRkHP facebook profile- https://www.facebook.com/suresh.kr.lrhs/ FACEBOOK PAGE- https://www.facebook.com/My-Student-S... facebook group NURSING NOTES- https://www.facebook.com/groups/24139... FOR MAKING EASY NOTES YOU CAN ALSO VISIT MY BLOG – BLOGGER- https://mynursingstudents.blogspot.com/ Instagram- https://www.instagram.com/mystudentsu... Twitter- https://twitter.com/student_system?s=08 #PEM, #HEALTH,#NEW,#BORN,#ASSESSMENT, #APPEARENCE,#PULSE,#GRIMACE,#REFLEX,#RESPIRATION,#RESUSCITATION,#NEWBORN,#BABY,#VIRGINIA, #CHILD, #OXYGEN,#CYANOSIS,#OPTICNERVE, #SARACHNA,#MYSTUDENTSUPPORTSYSTEM, #rashes,#nursingclasses, #communityhealthnursing,#ANM, #GNM, #BSCNURING,#NURSINGSTUDENTS, #WHO,#NURSINGINSTITUTION,#COLLEGEOFNURSING,#nursingofficer,#COMMUNITYHEALTHOFFICER
Definition
Epidemiology
Etiology
Pathophysiology
Classification
Diagnosis
Treatment
Anti Seizure Drugs Prices in Jordan
Two Medical cases
New drug approvals
More than 10 million people suffer from epilepsy in India.Seizures impact the lives of people with epilepsy and their family in many ways including creating barriers to employment and education and facing a sense of discrimination and isolation from their peers who donʼt understand what happens when they see a seizure occur. In India, epilepsy is still thought of as mental illness mainly due to lack of information on the condition among the general public.
This presentation touches every aspect of epilepsy
1. Overview of Epilepsy;
2. Type of Seizures;
3. Diagnosis and Management;
4. Psychological Issues; and
5. Social Perspectives.
Contents
Definition of Seizure and Epilepsy
Epidemiology
Classification of seizure
Pathophysiology of seizures
Evaluation Patients Presenting with Seizure
Focal seizure and related epilepsy syndromes
Generalized seizures and Epilepsy syndromes
Treatment of seizures and Epilepsy
Epilepsy is a disorder in which nerve cell activity in the brain is disturbed, causing seizures. Epilepsy may occur as a result of a genetic disorder or an acquired brain injury, such as a trauma or stroke. To join our daily online lessons on WhatsApp, send us a message now on +260977353901
the causes, pathophysiology, clinical manifestations, diagnosis and treatment of epilepsy has been discussed in detail with the perspective of a subject called pathophysiology in both medical sciences as well as the pharmaceutical sciences
THESE SLIDES ARE PREPAREED TO UNDERSTAND CHILD HEALTH DISORDERS IN EASY WAY Important links- NOTES- https://mynursingstudents.blogspot.com/ youtube channel https://www.youtube.com/c/MYSTUDENTSU... CHANEL PLAYLIST- ANATOMY AND PHYSIOLOGY-https://www.youtube.com/playlist?list=PL93S13oM2gAPM3VTGVUXIeswKJ3XGaD2p COMMUNITY HEALTH NURSING- https://www.youtube.com/playlist?list=PL93S13oM2gAPyslPNdIJoVjiXEDTVEDzs CHILD HEALTH NURSING- https://www.youtube.com/playlist?list=PL93S13oM2gANcslmv0DXg6BWmWN359Gvg FIRST AID- https://www.youtube.com/playlist?list=PL93S13oM2gAMvGqeqH2ZTklzFAZhOrvgP HCM- https://www.youtube.com/playlist?list=PL93S13oM2gAM7mZ1vZhQBHWbdLnLb-cH9 FUNDAMENTALS OF NURSING- https://www.youtube.com/playlist?list=PL93S13oM2gAPFxu78NDLpGPaxEmK1fTao COMMUNICABLE DISEASES- https://www.youtube.com/playlist?list=PL93S13oM2gAOWo4IwNjLU_LCuhRN0ZLeb ENVIRONMENTAL HEALTH- https://www.youtube.com/playlist?list=PL93S13oM2gAPkI6LvfS8Zu1nm6mZi9FK6 MSN- https://www.youtube.com/playlist?list=PL93S13oM2gAOdyoHnDLAoR_o8M6ccqYBm HINDI ONLY- https://www.youtube.com/playlist?list=PL93S13oM2gAN4L-FJ3s_IEXgZCijGUA1A ENGLISH ONLY- https://www.youtube.com/playlist?list=PL93S13oM2gAMYv2a1hFcq4W1nBjTnRkHP facebook profile- https://www.facebook.com/suresh.kr.lrhs/ FACEBOOK PAGE- https://www.facebook.com/My-Student-S... facebook group NURSING NOTES- https://www.facebook.com/groups/24139... FOR MAKING EASY NOTES YOU CAN ALSO VISIT MY BLOG – BLOGGER- https://mynursingstudents.blogspot.com/ Instagram- https://www.instagram.com/mystudentsu... Twitter- https://twitter.com/student_system?s=08 #PEM, #HEALTH,#NEW,#BORN,#ASSESSMENT, #APPEARENCE,#PULSE,#GRIMACE,#REFLEX,#RESPIRATION,#RESUSCITATION,#NEWBORN,#BABY,#VIRGINIA, #CHILD, #OXYGEN,#CYANOSIS,#OPTICNERVE, #SARACHNA,#MYSTUDENTSUPPORTSYSTEM, #rashes,#nursingclasses, #communityhealthnursing,#ANM, #GNM, #BSCNURING,#NURSINGSTUDENTS, #WHO,#NURSINGINSTITUTION,#COLLEGEOFNURSING,#nursingofficer,#COMMUNITYHEALTHOFFICER
Definition
Epidemiology
Etiology
Pathophysiology
Classification
Diagnosis
Treatment
Anti Seizure Drugs Prices in Jordan
Two Medical cases
New drug approvals
More than 10 million people suffer from epilepsy in India.Seizures impact the lives of people with epilepsy and their family in many ways including creating barriers to employment and education and facing a sense of discrimination and isolation from their peers who donʼt understand what happens when they see a seizure occur. In India, epilepsy is still thought of as mental illness mainly due to lack of information on the condition among the general public.
This presentation touches every aspect of epilepsy
1. Overview of Epilepsy;
2. Type of Seizures;
3. Diagnosis and Management;
4. Psychological Issues; and
5. Social Perspectives.
Contents
Definition of Seizure and Epilepsy
Epidemiology
Classification of seizure
Pathophysiology of seizures
Evaluation Patients Presenting with Seizure
Focal seizure and related epilepsy syndromes
Generalized seizures and Epilepsy syndromes
Treatment of seizures and Epilepsy
Epilepsy is a disorder in which nerve cell activity in the brain is disturbed, causing seizures. Epilepsy may occur as a result of a genetic disorder or an acquired brain injury, such as a trauma or stroke. To join our daily online lessons on WhatsApp, send us a message now on +260977353901
the causes, pathophysiology, clinical manifestations, diagnosis and treatment of epilepsy has been discussed in detail with the perspective of a subject called pathophysiology in both medical sciences as well as the pharmaceutical sciences
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
2. • Seizure is a paroxysmal, uncontrolled electrical
discharge of neurons in the brain that
interrupts normal function.
• Seizures may accompany a variety of
disorders, or they may occur spontaneously
without any apparent cause.
3. • Epilepsy is a condition in which a person has
spontaneous recurring seizures caused by a
chronic underlying condition.
• In the United States, it is estimated that more
than 3 million people have active epilepsy,
with 200,000 new cases diagnosed each year.
• National trends show that the incidence of
epilepsy is
4. Incidence
• increasing in older adults.
• New cases of epilepsy are more common in African
Americans and in socially disadvantaged populations.
• Males are slightly more likely to develop epilepsy
than females.
• People at high risk for developing epilepsy include
those with Alzheimer’s disease or those who have had a
stroke.
• The risk is also increased in the child of a person who
has epilepsy
5. Etiology and Pathophysiology
• Seizure disorders have many possible causes,
with the most common causes varying by age.
• The most common causes of seizure disorder
during the first 6 months of life are severe
birth injury, congenital defects involving the
central nervous system (CNS), infections, and
inborn errors of metabolism
6. • In people between 2 and 20 years of age, the primary
causes are birth injury, infection, trauma, and genetic
factors.
• In individuals between 20 and 30 years of age, seizure
disorder usually occurs as the result of structural
lesions, such as trauma, brain tumors, or vascular
disease.
• After 50 years of age, the primary causes of seizure
disorders are stroke and metastatic brain tumors.
• However, nearly 30% of all epilepsy cases are
idiopathic, called idiopathic generalized epilepsy (IGE),
meaning they are not attributable to a specific cause
7. pathophysiology
• The etiology of recurring seizures (epilepsy) has long been
attributed to a group of abnormal neurons (seizure focus) that
seem to undergo spontaneous firing.
This firing spreads by physiologic pathways to involve
adjacent or distant areas of the brain. If this activity spreads
to involve the whole brain, a generalized seizure occurs.
The factor that causes this abnormal firing is not clear.
Any stimulus that causes the cell membrane of the neuron to
depolarize induces a tendency for spontaneous firing
8. Clinical Manifestations and types of
seizure
• The specific clinical manifestations of a seizure
are determined by the site of the electrical
disturbance.
9. Phases of seizure
• Depending on the type,
• a seizure may progress through several phases:
• (1) the prodromal phase, with signs or activity
that precede a seizure
• (2) the aural phase, with a sensory warning
• (3) the ictal phase, with full seizure
• (4) the postictal phase, the period of recovery
after the seizure.
11. Generalized Seizures
• Generalized seizures involve both sides of the
brain and are characterized by bilateral
synchronous epileptic discharges in the brain
from the onset of the seizure.
• In most cases the patient loses consciousness
for a few seconds to several minutes.
13. Tonic-Clonic Seizures
• The most common generalized seizure is the
generalized tonic-clonic (formerly known as
grand mal) seizure.
• Tonic-clonic seizure is characterized by losing
consciousness and falling to the ground if the
patient is upright, followed by stiffening of the
body (tonic phase) for 10 to 20 seconds and
subsequent jerking of the extremities (clonic
phase) for another 30 to 40 seconds.
14. • Cyanosis
• excessive salivation,
• tongue or cheek biting
• incontinence may accompany the seizure
15. Typical Absence Seizures
• The absence seizure (formerly called petit mal) usually
occurs only in children and rarely continues beyond
adolescence.
• This type of seizure may cease altogether as the child
matures, or it may evolve into another type of seizure.
• The typical clinical manifestation is a brief staring spell
• resembling “daydreaming” that lasts only a few
seconds, so it often goes unnoticed.
• When untreated, the seizures may occur up to 100
times a day
16. Atypical Absence Seizures
• Another type of generalized seizure is atypical
absence seizure, which is characterized by a
staring spell accompanied by other signs and
symptoms, including brief warnings, peculiar
behavior during the seizure, or confusion after
the seizure
17. • It is longer lasting than a typical absence
seizure and may be associated with loss of
postural tone.
18. • Other Types of Generalized Seizures. Other
generalized seizures are myoclonic, atonic,
tonic, and clonic seizures
19. myoclonic seizure
• A myoclonic seizure is characterized by a
sudden, excessive jerk of the body or
extremities.
• The jerk may be forceful enough to hurl the
person to the ground.
• These seizures are brief and may occur in
clusters.
20. Atonic seizure
• An atonic (“drop attack”) seizure involves
either a tonic
• episode or a paroxysmal loss of muscle tone
and begins suddenly with the person falling to
the ground.
• Consciousness usually returns by the time the
person hits the ground, and normal activity
can be resumed immediately.
21. • Patients with this type of seizure are at a great
risk of head injury and often have to wear
protective helmets.
22. tonic seizure
• A tonic seizure involves a sudden onset of
maintained increased tone in the extensor
muscles.
• These patients often fall.
• .
23. Clonic seizures
• Clonic seizures begin with loss of
consciousness and sudden loss of muscle
tone, followed by limb jerking that may or
may not be symmetric
24. Focal Seizures
• Focal seizures, also called partial or partial
• focal seizures, are the other major class of
seizures
• Focal seizures begin in one hemisphere of the
brain in a specific region of the cortex, as
indicated by the EEG.
• They produce signs and symptoms related to
the function of the area of the brain involved
25. Complications
• Physical.
• Status epilepticus is a state of continuous
seizure activity or a condition in which
seizures recur in rapid succession without
return to consciousness between seizures
26. • It is the most serious complication of epilepsy
and is a neurologic emergency.
• Status epilepticus can occur with any type of
seizure.
• During repeated seizures the brain uses more
energy than can be supplied.
27. • Neurons become exhausted and cease to
• function.
• Permanent brain damage may result.
• Tonic-clonic status epilepticus is the most
dangerous because it can cause ventilatory
insufficiency, hypoxemia, cardiac
dysrhythmias, hyperthermia, and systemic
acidosis, all of which can be fatal
28. Psychosocial
• Perhaps the most common complication of
seizure disorders is the effect it has on a
patient’s lifestyle.
• The patient may develop ineffective coping
methods because of the psychosocial
problems related to having a seizure disorder.
29. Diagnostic Studies
• The most useful diagnostic tools are an
accurate and comprehensive description of
the seizures and the patient’s health history
30. • The EEG is a useful diagnostic adjuvant to the
history, but only if it shows abnormalities.
• Abnormal findings help determine the type of
seizure and help pinpoint the seizure focus.
• Ideally, an EEG should be done within 24
hours of a suspected seizure
31. • A complete blood count, serum chemistries,
studies of liver and kidney function, and a
urinalysis should be done to rule
out metabolic disorders.
• A CT scan or MRI should be done in any new-
onset seizure to rule out a structural lesion.
• Cerebral angiography, single-photon emission
computed tomography (SPECT), magnetic
resonance spectroscopy (MRS), MRA, and
positron emission tomography (PET) may be used
in selected clinical situations
32. Collaborative Care
• The primary drugs to treat generalized tonic-
clonic and focal seizures are phenytoin
(Dilantin), carbamazepine (Tegretol),
phenobarbital, divalproex, and primidone
(Mysoline).
• The drugs used to treat absence and
myoclonic seizures include ethosuximide
(Zarontin), divalproex, and clonazepam
• (Klonopin)
33. • Other antiseizure drugs include gabapentin,
topiramate,
lamotrigine (Lamictal), tiagabine (Gabitril), levetiracetam
• (Keppra), and zonisamide (Zonegran).
• Some of these drugs are broad spectrum and appear to
be effective for multiple seizure types.
• Pregabalin (Lyrica) is used as an “add-on” for control of
• focal seizures that are not successfully managed with a
single medication
34. • Treatment of status epilepticus requires
initiation of a rapid- acting IV antiseizure drug.
• The drugs most commonly used are
lorazepam (Ativan) and diazepam (Valium).
Because these are short-acting drugs, their
administration is followed with long- acting
drugs such as phenytoin or phenobarbital
35. Surgical Therapy
• A significant number of patients whose
epilepsy is not controlled with drug therapy are
candidates for
surgical intervention to remove the epileptic focus or
prevent
spread of epileptic activity in the brain .
• The most common surgical intervention is an anterior
temporal lob resection.
• Approximately 70% of patients are essentially seizure
free after this procedure
36. • The benefits of surgery include cessation or reduction in
frequency of the seizures.
• An extensive preoperative evaluation is
important, including continuous EEG monitoring and other
specific tests to ensure precise localization of the focal point.
• Surgical candidates must meet three requirements:
• (1) a confirmed diagnosis of epilepsy
• (2) an adequate trial with drug therapy without satisfactory
results
• (3) a defined electro clinical syndrome (type of seizure
disorder).
37. Other Therapies
• Vagal nerve stimulation is used as an
adjunct to medications when surgery is not
feasible.
• The exact mechanism of action is unknown,
but it is thought to interrupt the
synchronization of epileptic brain wave
activity and stop excessive discharge of
neurons
38. Diet
• The ketogenic diet is a special high-fat, low-
carbohydrate
diet that has been used to control seizures in some
people with epilepsy.
• When a person is on this diet, ketones are produced
and pass into the brain and replace glucose as an energy
source.
• The diet may be effective for some patients with drug-
resistant epilepsy, but the long-term effects of the diet
are not clear.
• Patients on this diet who use anticoagulants need close
monitoring for bleeding
39. • Biofeedback to control seizures is aimed at
teaching the patient to maintain a certain
brain wave frequency that is refractory to
seizure activity.
• Further trials are needed to assess the
effectiveness of biofeedback for seizure control.
40. Nsg diagnosis
• • Ineffective breathing pattern related to
neuromuscular impairment
• • Ineffective self-health management related
to drug therapy and lifestyle adjustments
• • Risk for injury related to loss of
consciousness during seizure activity and
postictal physical weakness
41. interventions
• When a seizure occurs, carefully observe and
record details of the event because the
diagnosis and subsequent treatment
• . Note all aspects of the seizure.
42. • Both subjective data (usually the only type of data in
the
aural phase) and objective data are important.
• Note the exact onset of the seizure (which body part
was affected first and how); the course and nature of
the seizure activity (loss of consciousness, tongue
biting, automatisms, stiffening, jerking, total lack of
muscle tone);
• the body parts involved and their sequence of
involvement; and autonomic signs, such as dilated
pupils, excessive salivation, altered breathing, cyanosis,
flushing, diaphoresis, or incontinence.
43. • After the seizure the patient may require
repositioning to open and maintain the
airway, suctioning, and oxygen.
• A seizure can be frightening for the patient
and for others who witnessed it.
• Assess the level of their understanding and
provide information about how and why the
event occurred.