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Ganesh N Rajan
Scope of this presentation
          What Schizophrenia is and what it is not
          What is the basis for the disability and where
           does it occur
          Onset and symptoms
          Recognizing the condition and what to do
          Signs of recovery


10/25/12                     Ganesh N Rajan                 2
What is Schizophrenia

           Schizophrenia is a mental manifestation
                    of a physical illness.
                       Nothing more!!!



10/25/12                   Ganesh N Rajan            3
What Schizophrenia is not
  Schizophrenia is not a multiple or split
   personality
  Schizophrenia is not caused by bad
   parenting
  Schizophrenia is not the result of
   childhood trauma
  Most people with schizophrenia are not
   violent or dangerous
10/25/12            Ganesh N Rajan            4
What is the basis for Schizophrenia?

A disturbance in the brain’s functioning
              Inappropriate levels of Neurotransmitters in
               the brain (Chemicals that carry messages
               from one brain nerve cell to another)
                Dopamine – Too much in certain areas of the
                 brain
                Serotonin – Plays a contributory role


10/25/12                        Ganesh N Rajan                 5
Where does Schizophrenia occur?

           Occurs in all races, cultures, socio-economic
            classes, and both genders
           Generally strikes young people for the first
            time in late teens or early twenties (Typical)
           Generally preceded by a perceived
            contradiction or paradox or mysticism in
            one’s understanding of reality

10/25/12                      Ganesh N Rajan                 6
Onset
  Families are often not aware for a long time
   Sometimes a gradual build-up of
    symptoms that may or may not lead to an
    ‘acute’ or ‘crisis’ episode
   Sometimes strikes quickly with dramatic
    behavior changes in a matter of few weeks
    or even days
10/25/12             Ganesh N Rajan              7
Symptoms
  Positive – Those that are present but
   should be absent
  Negative – Those that are absent but
   should be present

 Symptoms vary greatly from one individual to
    another. No one manifestation is common to all


10/25/12               Ganesh N Rajan                8
Positive Symptoms
          Delusions
          Hallucinations
          Thought disorders (Jumbled thoughts)
          Excitement
          Grandiosity
          Suspiciousness/ Sense of persecution
          Hostility
10/25/12                  Ganesh N Rajan          9
Negative Symptoms
          Blunted feelings              (Instead of sharpness)
          Emotional withdrawal          (Instead of emotional stability)

          Poor ability to get along (Instead of ability to establish
                                                rapport)
          Passive/ Apathetic/           (Instead of assertive/ involved/
           Social withdrawal                  socially skilled)
          Difficulty in abstract        (Instead of ease and normality)
           thinking
          Lack of spontaneity           (Instead of apt spontaneity)
          Stereotyped thinking          (Instead of an open mind)
10/25/12                            Ganesh N Rajan                          10
What is the trigger
    The stress-diathesis explanation

    A combination of genetic, physiological and
       stressful conditions


                         ?
10/25/12              Ganesh N Rajan              11
Early Symptoms
          You are more suspicious and anxious
          Your mood alternates between very happy and very sad
          You have a sudden difficulty in sticking to routines
          You have difficulty in concentrating or remembering
           things
          Sometimes you feel like eating and sleeping a lot and
           sometimes, not at all
          You don’t feel very motivated
          You are less concerned about things
          You seem to be thinking slowly or have fewer thoughts

10/25/12                       Ganesh N Rajan                      12
More florid symptoms
          Your sense of sight, hearing, touch and taste is altered
          You see the world differently from others
          You think you have access to secret knowledge or
           information
          You trust people less and become more suspicious
          You are influenced by external stimuli, usually with
           no obvious source
          You think you know the actual intentions of others
          You don’t understand why others cannot see what is
           clear to you

10/25/12                        Ganesh N Rajan                        13
Changes in behavior that others can see
           Sleep problems
           Lack of energy, interest and motivation
           A sudden change in behavior or beliefs
           Easily irritable or angry
           A development of or increase in remoteness
           A sudden change of routine
           Increased hostility or suspiciousness
           Sudden and unrealistic confidence in abilities
           Abrupt carelessness in personal hygiene
           Unusual and drastic changes in food habits
           Forgetfulness or confusion
10/25/12                       Ganesh N Rajan                14
What to do
          Provide professional help
          Do not confront
          Postpone psycho-education of the affected person until insight
          Don’t rationalize with him/ her
          Share mistrust and acknowledge beliefs
          Establish that it is okay to have different points of view
          Use examples from your own life (trouble with authority,
           experiencing failure, etc.)
          Suggest alternatives (e.g. Other people have found that such
           feelings could arise from stress…)
          Provide tactful nudges towards reality and be patient while
           awaiting remission
10/25/12                            Ganesh N Rajan                        15
Anticipate…
          Demoralization, sense of failure, despair and
           depression as insight is gained
          Overreaching of vocational and other goals
          A possible tendency for substance abuse

 Show how apparent failure
                         is actually a sign of progress


10/25/12                     Ganesh N Rajan             16
Encourage
              Conversation
              Sticking to a routine
              Adopting medication
              Maintaining a record
              Creative pursuits


10/25/12               Ganesh N Rajan   17
Early signs of recovery
    Receding of positive symptoms
               Auditory hallucinations go farther away
               Visual hallucination become less defined
               Olfactory hallucinations are less frequent
               Delusions become toned down
               There is an increased willingness to listen
                and trust


10/25/12                      Ganesh N Rajan                  18
Later signs of recovery
 Lessening of negative symptoms
           A relative increase in socialization
           Willingness to talk of the disability in the
            past tense
           Increased participation in chores
           Beginning to actively read and write
           Adopting challenges and hobbies that are
            appropriate (E.g. Photography, painting,
            music, writing, academics, etc.)
10/25/12                    Ganesh N Rajan                 19
An Insider’s View
 Key insights to establish in the afflicted individual
 are…
 … that regardless of whether the ‘reality’ perceived by
 him or her is true or not, would he or she feel productive,
 proactive and confident while continuing to harbor the
 beliefs and perceptions he or she has currently?
 … a belief that one need not compare oneself with
 anyone else in his or her unique journey through life
 … acceptance of the ‘here and now’ with a willingness to
 patiently progress can override anything that he or she
 perceives is holding him or her back

10/25/12                  Ganesh N Rajan                   20
Acknowledgements
          Dr. S. Kalyanasundaram
          SCARF, India
          Dr Leston Havens
          Dr S Mohan Raj
          Dr Peter Weiden
          Dr Vijay Nagaswami
          www.psychiatry24x7.com
          www.mentalhealth.com


                     THANK YOU
10/25/12                    Ganesh N Rajan   21

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Schizophrenia - A Primer

  • 2. Scope of this presentation  What Schizophrenia is and what it is not  What is the basis for the disability and where does it occur  Onset and symptoms  Recognizing the condition and what to do  Signs of recovery 10/25/12 Ganesh N Rajan 2
  • 3. What is Schizophrenia Schizophrenia is a mental manifestation of a physical illness. Nothing more!!! 10/25/12 Ganesh N Rajan 3
  • 4. What Schizophrenia is not  Schizophrenia is not a multiple or split personality  Schizophrenia is not caused by bad parenting  Schizophrenia is not the result of childhood trauma  Most people with schizophrenia are not violent or dangerous 10/25/12 Ganesh N Rajan 4
  • 5. What is the basis for Schizophrenia? A disturbance in the brain’s functioning  Inappropriate levels of Neurotransmitters in the brain (Chemicals that carry messages from one brain nerve cell to another)  Dopamine – Too much in certain areas of the brain  Serotonin – Plays a contributory role 10/25/12 Ganesh N Rajan 5
  • 6. Where does Schizophrenia occur?  Occurs in all races, cultures, socio-economic classes, and both genders  Generally strikes young people for the first time in late teens or early twenties (Typical)  Generally preceded by a perceived contradiction or paradox or mysticism in one’s understanding of reality 10/25/12 Ganesh N Rajan 6
  • 7. Onset Families are often not aware for a long time  Sometimes a gradual build-up of symptoms that may or may not lead to an ‘acute’ or ‘crisis’ episode  Sometimes strikes quickly with dramatic behavior changes in a matter of few weeks or even days 10/25/12 Ganesh N Rajan 7
  • 8. Symptoms  Positive – Those that are present but should be absent  Negative – Those that are absent but should be present Symptoms vary greatly from one individual to another. No one manifestation is common to all 10/25/12 Ganesh N Rajan 8
  • 9. Positive Symptoms  Delusions  Hallucinations  Thought disorders (Jumbled thoughts)  Excitement  Grandiosity  Suspiciousness/ Sense of persecution  Hostility 10/25/12 Ganesh N Rajan 9
  • 10. Negative Symptoms  Blunted feelings (Instead of sharpness)  Emotional withdrawal (Instead of emotional stability)  Poor ability to get along (Instead of ability to establish rapport)  Passive/ Apathetic/ (Instead of assertive/ involved/ Social withdrawal socially skilled)  Difficulty in abstract (Instead of ease and normality) thinking  Lack of spontaneity (Instead of apt spontaneity)  Stereotyped thinking (Instead of an open mind) 10/25/12 Ganesh N Rajan 10
  • 11. What is the trigger The stress-diathesis explanation A combination of genetic, physiological and stressful conditions ? 10/25/12 Ganesh N Rajan 11
  • 12. Early Symptoms  You are more suspicious and anxious  Your mood alternates between very happy and very sad  You have a sudden difficulty in sticking to routines  You have difficulty in concentrating or remembering things  Sometimes you feel like eating and sleeping a lot and sometimes, not at all  You don’t feel very motivated  You are less concerned about things  You seem to be thinking slowly or have fewer thoughts 10/25/12 Ganesh N Rajan 12
  • 13. More florid symptoms  Your sense of sight, hearing, touch and taste is altered  You see the world differently from others  You think you have access to secret knowledge or information  You trust people less and become more suspicious  You are influenced by external stimuli, usually with no obvious source  You think you know the actual intentions of others  You don’t understand why others cannot see what is clear to you 10/25/12 Ganesh N Rajan 13
  • 14. Changes in behavior that others can see  Sleep problems  Lack of energy, interest and motivation  A sudden change in behavior or beliefs  Easily irritable or angry  A development of or increase in remoteness  A sudden change of routine  Increased hostility or suspiciousness  Sudden and unrealistic confidence in abilities  Abrupt carelessness in personal hygiene  Unusual and drastic changes in food habits  Forgetfulness or confusion 10/25/12 Ganesh N Rajan 14
  • 15. What to do  Provide professional help  Do not confront  Postpone psycho-education of the affected person until insight  Don’t rationalize with him/ her  Share mistrust and acknowledge beliefs  Establish that it is okay to have different points of view  Use examples from your own life (trouble with authority, experiencing failure, etc.)  Suggest alternatives (e.g. Other people have found that such feelings could arise from stress…)  Provide tactful nudges towards reality and be patient while awaiting remission 10/25/12 Ganesh N Rajan 15
  • 16. Anticipate…  Demoralization, sense of failure, despair and depression as insight is gained  Overreaching of vocational and other goals  A possible tendency for substance abuse Show how apparent failure is actually a sign of progress 10/25/12 Ganesh N Rajan 16
  • 17. Encourage  Conversation  Sticking to a routine  Adopting medication  Maintaining a record  Creative pursuits 10/25/12 Ganesh N Rajan 17
  • 18. Early signs of recovery Receding of positive symptoms  Auditory hallucinations go farther away  Visual hallucination become less defined  Olfactory hallucinations are less frequent  Delusions become toned down  There is an increased willingness to listen and trust 10/25/12 Ganesh N Rajan 18
  • 19. Later signs of recovery Lessening of negative symptoms  A relative increase in socialization  Willingness to talk of the disability in the past tense  Increased participation in chores  Beginning to actively read and write  Adopting challenges and hobbies that are appropriate (E.g. Photography, painting, music, writing, academics, etc.) 10/25/12 Ganesh N Rajan 19
  • 20. An Insider’s View Key insights to establish in the afflicted individual are… … that regardless of whether the ‘reality’ perceived by him or her is true or not, would he or she feel productive, proactive and confident while continuing to harbor the beliefs and perceptions he or she has currently? … a belief that one need not compare oneself with anyone else in his or her unique journey through life … acceptance of the ‘here and now’ with a willingness to patiently progress can override anything that he or she perceives is holding him or her back 10/25/12 Ganesh N Rajan 20
  • 21. Acknowledgements  Dr. S. Kalyanasundaram  SCARF, India  Dr Leston Havens  Dr S Mohan Raj  Dr Peter Weiden  Dr Vijay Nagaswami  www.psychiatry24x7.com  www.mentalhealth.com THANK YOU 10/25/12 Ganesh N Rajan 21