The document introduces the Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs. These programs are the largest sources of early-stage funding for small businesses in the US. They provide over $2.5 billion annually across 11 federal agencies for SBIR and 5 agencies for STTR. The programs have three phases - Phase I funds concept exploration, Phase II funds R&D development, and Phase III supports commercialization. The goals are to stimulate innovation, support small businesses to meet federal R&D needs, and increase commercialization of technologies developed with federal funding.