1. SHIHENG FAN
230 E University Pkwy https://www.linkedin.com/in/shihengfan 443-310-8639
Baltimore, MD 21218 sfan4@jhu.edu
EDUCATION
Johns Hopkins University Baltimore, MD
Master of Science in Chemical and Biomolecular Engineering, GPA: 3.65 Sept. 2015 – Dec 2016
Relevant Coursework: Python, Computational Genomics, Computational Protein Structure Prediction & Design, Differential Equations,
Supramolecular Materials & Nanomedicine, Chemical & Biomolecular Separation, Advanced Thermodynamics & Kinetics
Boston University Boston, MA
Bachelor of Arts in Biology, GPA: 3.40, Dean’s List – Spring 2011& 2014 Sept. 2014
Relevant Coursework: Java, Multivariable Calculus, Statistics, Organic Chemistry with Qualitative Analysis, Synthetic and Analytical
Chemistry, General Physics, Human Physiology, Genetics, Cell Biology, Microbiology, Marine Biology, Ecology
RESEARCH EXPERIENCE
Johns Hopkins University Baltimore, MD
Graduate Research Project Group Leader Jan. – May 2016
Advisor: Prof. Jeffery Gray
• Validated PyRosetta energy score function for DNA-protein-binding rescue through novel p53 “hotspot” mutations
• Explored Monte Carlo optimization on DNA-protein docking via parallel computing and HPC (MARCC Blucrab 20,000 cores)
Boston University Center for Molecular Discovery Boston, MA
Undergraduate Researcher Sept. 2011– Sept. 2014
Advisor: Prof. James Panek, Prof. Salomon Amar, Dr. Kaicheng Zhu
Medicinal Chemistry Optimization Studies for Anti-inflammatory Therapeutics (successful candidate for NIH Grant)
• Investigated the synthetic pathways for structurally modified analogs of a natural compound that stimulates anti-inflammatory
processes in mammalian cells
• Enhanced the potency and pharmacokinetic stability of the drug through carbohydrate as well as amino acid modification
• Developed and optimized the total synthesis procedures for two final products
• Accelerated the project in meeting the deadline of a $500,000 funding application at the National Institutes of Health
Chemical Reaction Methodology Development Using Allenyl-silanes
• Developed and refined a previously proposed chemical pathway for synthesizing homopropargylic ethers in desired chirality with
high yield and diastereomer ratio
• Manufactured and screened over 30 different combinations of molecular structures
LEADERSHIP & WORK EXPERIENCE
Pixelligent Technologies LLC Baltimore, MD
Associate Scientist Intern June – Aug. 2016
• Designed formulations and prepared nano-composites for customer orders
• Explored qualification studies and promoted an alpha-stage ingredient to commercially producible level
• Ensured product quality through preforming key characterization tasks
Johns Hopkins University Baltimore, MD
Graduate Group Project Oct. – Dec. 2015
• Led a team of graduate students in composing a product analysis of BMW i3 vehicle
• Investigated the underlying economic advantages and research facts behind its desired performance
Boston University School of Law Boston, MA
IT Help Center Staff Sept. 2011 – May 2013
• Supervised customer service and malfunctions for over 100 computers as well as 4 advanced laser printers
• Ensured the proper functioning of studying equipment for law school students over weekends and school holidays
Boston University Chemia Boston, MA
Organic Chemistry Tutor Sept. 2011 – May 2012
• Tutored over 5 students for 10 hours a week to improve their comprehension on course materials
• Developed and prepared demonstration questions for difficult concepts
DDS. Vivian W. Cui's Dental Clinic San Francisco, CA
Clinical Assistant May – Aug. 2011
• Delivered dental instruments as requested during hygiene treatment
• Performed sterilization and disinfection procedures for used instruments routinely
2. AWARDS & PRESENTATIONS
Johns Hopkins University Baltimore, MD
Whiting School of Engineering ChemBE Master’s Academic Scholarship Fall 2016
• Received a fellowship award equivalent to $20,400 financial support
Boston University Boston, MA
Undergraduate Research Opportunities Program Award Summer 2013 & 2014
• Received two $4,200 fellowship awards to perform research at Prof. James Panek's Lab
• Presented scientific posters for the 16th & 17th Annual Boston University Undergraduate Research Symposium
TECHNICAL SKILLS
• Software: Java, Python, MATLAB, Polymath, ChemDraw, MestReNova, MS Office Word, Excel, PowerPoint
• Laboratory: Cell Culture, Liquid Chromatography, HPLC, Solvent Distillation, Crystallization, NMR, IR, LC-MS, Spin-coating,
UV/Vis, Viscometer, Profiler, Refractometer
CONTRIBUTED PUBLICATION
Boston University Center for Molecular Discovery Boston, MA
Noted Contributor in Acknowledgement
Cai, Bin, James S. Panek, and Salomon Amar. "Convergent Synthesis of Novel Muramyl Dipeptide Analogues: Inhibition of
Porphyromonas gingivalis-Induced Pro-inflammatory Effects by High Doses of Muramyl Dipeptide."Journal of Medicinal
Chemistry 59.14 (2016): 6878-6890.