Auf der Suche nach Innovationen werden viele Wege gegangen, von denen nicht alle wirklich zielgerichtet sind, sondern oft den Zufall als Freund haben. Design Thinking ist dabei ein vielversprechender und vor allem ganzheitlicher Ansatz, der das systematische Produzieren von Innovationen möglich macht und fördert. Neben den theoretischen Grundlagen steht vor allem auch die Praxis im Vordergrund des kurzweiligen Vortrags.
Live human study training tens of thousands of laypersons all the signs of respiratory emergency, then telling them to give chest compressions only. That's assault & murder.
Auf der Suche nach Innovationen werden viele Wege gegangen, von denen nicht alle wirklich zielgerichtet sind, sondern oft den Zufall als Freund haben. Design Thinking ist dabei ein vielversprechender und vor allem ganzheitlicher Ansatz, der das systematische Produzieren von Innovationen möglich macht und fördert. Neben den theoretischen Grundlagen steht vor allem auch die Praxis im Vordergrund des kurzweiligen Vortrags.
Live human study training tens of thousands of laypersons all the signs of respiratory emergency, then telling them to give chest compressions only. That's assault & murder.
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
CDSCO and Phamacovigilance {Regulatory body in India}NEHA GUPTA
The Central Drugs Standard Control Organization (CDSCO) is India's national regulatory body for pharmaceuticals and medical devices. Operating under the Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India, the CDSCO is responsible for approving new drugs, conducting clinical trials, setting standards for drugs, controlling the quality of imported drugs, and coordinating the activities of State Drug Control Organizations by providing expert advice.
Pharmacovigilance, on the other hand, is the science and activities related to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems. The primary aim of pharmacovigilance is to ensure the safety and efficacy of medicines, thereby protecting public health.
In India, pharmacovigilance activities are monitored by the Pharmacovigilance Programme of India (PvPI), which works closely with CDSCO to collect, analyze, and act upon data regarding adverse drug reactions (ADRs). Together, they play a critical role in ensuring that the benefits of drugs outweigh their risks, maintaining high standards of patient safety, and promoting the rational use of medicines.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...
Respiratory Assist Essential for Respiratory Emergencies
1. Read with grave concern the article by Leece et al.1 Teaching layperson’s the signs of respiratory
emergency, then training the layperson to give chest compression’s only.
Omitted from the article the “POINT” Prevent Overdose IN Toronto, signs of opioid
overdose, from the training literature.2-4
Can’t wake the person up
Breathing is very slow, erratic or has stopped
Deep snoring or gurgling sounds
Fingernails or lips are blue or purple
Body is very limp
Pupils are very small
These signs would indicate a poisoned patient in coma, suffering a respiratory
emergency. Author’s reference (26) states respiratory assist.5 This would be consistent with the
medical evidence worldwide.6-8
Cardiac arrest is secondary to respiratory arrest and is associated with sever hypoxia,
prognosis is poor.8 Patient now needs Advanced Cardiac Life Support (ACLS) beyond the scope of
laypersons.9 Keep coma patient alive rescue breaths, Basic Life Support (BLS).
Authors quote “Significant numbers of opioid-related deaths involve poly substance
overdose with cardio toxic drugs.” The author’s reference (29) makes slim mention of cardio
toxic drugs. Stimulant drugs and other toxins may causeadysrhythmia (control with ACLS), drugs
of abuse cause death from acute respiratory failure.10 Cyanosis can be cardio toxic, myocardial
infarction lack of oxygen in blood stream, every tissue and all organs dying lack of oxygen.
Authors quote “Painful stimulation (such as chest compressions) may be an effective
means of increasing respiratory drive.” Needs redress (primum non nocere) complications of
chest compressions is endless.11 BLS (rescue breathing) adds oxygen to the blood stream.
Can find no consensus for chest compressions only for respiratory emergencies, including
opioid poisoning (overdose).
References
1. Leece PN, Hopkins S, Marshall C, Orkin A, Gassanov MA, Shahin RM. Development and
Implementation of an Opioid Overdose Prevention and Response Program in Toronto,
2. Ontario. Canadian Journal Public Health 2013;104(3):e200-04.
http://journal.cpha.ca/index.php/cjph/article/view/3788
2. OHRDP ‘NaloxoneTrainingVideo’Availableat: https://vimeo.com/68067103 (Accessed
September 10, 2015).
3. TorontoPublicHealth‘POINT’(PreventingOverdose IN Toronto) Available at:
https://www.cpso.on.ca/uploadedFiles/members/Meth-conf-POINT-PP.pdf (Accessed
September10,2015).
4. Toronto Harm Reduction‘NALOXONE: Saves lives, learn how, share the knowledge’
Available at: http://www.youtube.com/watch?v=zlbkU5IK5Do (AccessedSeptember10,
2015).
5. VandenHoek TL, Morrison LJ, Shuster M, Donnino M, Sinz E, Lavonas EJ.et al. Part 12
Cardiac arrest in special situations: 2010 American Heart Association Guidelines for
Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation
2010;122(18 Suppl 3):S829-S861.
6. UNODC/WHO 2013 ‘Opioid Overdose: preventing and reducing opioid overdose
mortality’. Available at: https://www.unodc.org/docs/treatment/overdose.pdf
(Accessed September 10, 2015).
7. Deakin CD, Morrison LJ, Morley PT, Calloway CW, Kerber RE, Kronick SL. et al. Part 8:
Advanced life support: 2010 International Consensus on Cardiopulmonary Resuscitation
and Emergency Cardiovascular Care Science with Treatment Recommendations.
Resuscitation 2010;81S:e93-e174.
8. Soar J, Perkins GD, Abbas G, Alfonzo A, Barrelli A, Bierens JJLM. et al. Section 8: Cardiac
arrest in special circumstances: 2010 European Resuscitation Council Guidelines for
Resuscitation. Resuscitation 2010;81:1400-33.
9. Roberts JR. Dissecting the ACLS guidelines on toxic ingestions. Emergency Medicine
News 2011;33(10):16-18.
10. Wilson KC, Saukkonen JJ. Acute respiratory failure from abused substances. Journal
Intensive Care Medicine 2004;19(4):183-93.
11. Atcheson SG, Fred HL. Complications of cardiac resuscitation. American Heart Journal
1975;89(2):263-65.