Sharing experiences and personal journey to SARC students.

1. Dirgha Raj Joshi, PhD
Email: djmeropaila121@gmail.com
Date: 2022.09.30
Research Needs in Medical Science:
Opportunities and Challenges

2. My Journey Towards Pharmacy
2
Towards formal education
 SLC, Government School: 2008
 D. Pharmacy, CTEVT: 2010
 B. Pharmacy, Pokhara University: 2015
 MS Pharmacy, Wonkwang University: 2018
 PhD, Yonsei University: 2022
 Postdoctoral research going
Motivation Towards Pharma Study

4. Publication of
Undergraduate research
Learning during
Undergraduate
Cow urine samples from
different altitude of Nepal
Now here….

5. Cow urine
Gomutra Beer Gomutra promoted
organic synthesis
USE OF COW URINE: Possibilities in the New Dimension
आज फ
े री क
ु क
ु रको मुत खाएर आईस्?, हैन गाईको मुत खाको !!! @Dirgha Raj Joshi

6. Why Indolizine Synthesis
M. Scholtz, Chem. Ber., 1912, 45, 734
First discovery of indolizine in 1890
A. Angeli, Gazz. Chim. Iial. 1890, 26, 1793
EJMC, 2011, 46, 5237-5257; Joshi & Kim, J. Org. Chem. 2020
Discovery, Construction & Functionalization Biologically Active Indolizines
First synthesis of indolizine by Scholtz in 1912
Org. Biomol. Chem., 2015,13, 10986
C3 functionalization of indolizines
Angelo Angeli (1864 –1931), Italy
Famus for Angeli–Rimini reaction

7. Summary of my few Synthetic Work

8. Scientific outcomes

9. Patents Outcomes

12. Why to do Research?

13. Treatment Systems
 Allopathic
 Ayurvedic/ Chinese Traditional Medicine/ Japanese Traditional Medicine/ Korean Traditional Medicine
 Homeopathic
 Unani Medicine
 Siddha medicine
 Traditional Tibetan medicine
 Shamanism Practices

14. What you
think?

15.  The Patent Act of 1790, USA
 Provisional Regulations for Monopoly, 1871, Japan
 The Patent, Design and Trade Mark Act, 1965, Nepal
 The Patents Act, 1970, India
Few patent acts and where we are?

16. Drug Discovery Process

18. Typical
Target
Identification
Process

19. Research is a collaborative approach

20. Literature
Review
Other: Reaxys, Semantic Scholar,
Microsoft Academic, Base, Core,
Science.gov, Baidu Scholar,
RefSeek, WorldWideScience etc.
Search Engine

22. https://publons.com/ https://orcid.org/my-orcid?orcid=0000-0002-0303-5677
Scientific Profile for Your Growth

23. https://www.researchgate.net https://www.linkedin.com/feed/
https://yonsei.academia.edu https://scholar.google.com
Scientific Profile for Your Growth

24. https://academictree.org/chemistry
Scientific Profile for Your Growth

26. Compulsion
Why Higher Education?
Need
…
….
….
…..

27. Undergraduate
No Job Further Study………MS, PhD
+2
No Job Further Study
SLC/SEE
No Job Further Study
Why Higher Education?
…….

28. Internal Strength
Stress
Internal
Strength
Stress
What develops ego on you?

29. Who is a Leader??

30. इतत ते ज्ञानमाख्यातं गुह्याद् गुह्यतरं मया |
तिमृश्यैतदशेषेण यथेच्छतस तथा क
ु रु || 18.63||
कममण्येिातिकारस्ते मा फलेषु कदाचन |
मा कममफलहेतुर्भममाम ते सङ्गोऽस्त्वकममतण || 2.47 ||
You have a right to perform your
prescribed duties, but you are not
entitled to the fruits of your actions.
Never consider yourself to be the cause
of the results of your activities, nor be
attached to inaction.
Thus, I have explained to you this
knowledge that is more secret than
all secrets. Ponder over it deeply,
and then do as you wish.
do as you wish

31. 1. Korea: world's biggest investor in research. http://www.koreatimes.co.kr/www
/opinion/2017/07/162_233540.html
2. Moving ahead. http://kathmandupost.ekantipur.com/news/2015-12-29/moving-h
ead.html
3. Message to President Moon. https://www.koreatimes.co.kr/www/opinion/2018/
11/198_257259.html
4. My Dream. https://thehimalayantimes.com/opinion/topics-my-dream/
5. Covid-19 response: Can Nepal learn from South Korea? https://english.online
khabar.com/covid-19-response-can-nepal-learn-from-south-korea.html
Other than research

32. जुन देशका युिाले आफ्नै
देशमा आफ्नो र्तिष्य
देख्दैनन्, त्यो देशको र्तिष्य
कतहल्यै उज्वल हुँदैन l
एक संकल्प राष्ट्र का लागी ललउ !!!
देशले क
े लदयो न भन ं साथी हो, देशलाई क
े लदए त्यो भन ं साथी हो |