This study examined whether deception in facial expressions and micro-expressions shows universal cues across cultures. Fifty participants from diverse backgrounds completed a survey involving micro-expression detection and judging the truthfulness of statements. The results found a weak positive correlation between micro-expression detection scores and the ability to detect deceptive statements. Additionally, Asian participants performed significantly worse at detecting deception compared to American participants, suggesting cultural differences exist. The study provides initial evidence that some deception cues may be universal, but culture also influences detection abilities. Continued cross-cultural research could help understand deception and nonverbal communication between groups.