The document provides information on important artists and works from Italy, Flanders, and Germany in the 15th century before the Protestant Reformation, including Jan van Eyck, Hubert van Eyck, Duccio, Piero della Francesca, Mantegna, Botticelli, Leonardo da Vinci, Bosch, and Dürer. It summarizes their major paintings and discusses the development of oil painting, linear perspective, printing, and other artistic innovations during this period.