Apresentação feita por Rob George no seminário internacional Conass Debate – Cuidados Continuados e Integrados: um desafio para o presente, realizado em Brasília nos dias 26 e 27 de dezembro.
Putting Fuel on the Fire - Advocacy in the NorthCitizen Network
Simon Duffy gave this talk at the North East and Cumbria Advocacy Conference on 30th March 2017 in Newcastle. He explores why citizenship matters and what are the challenges we face in the years ahead.
Ageism effects all of us – whether we are young, old, or somewhere in between. Ageism is a broad issue throughout the UK that exists in many different areas in society. In this webinar we will discuss this issue and the different areas of ageism that exist within our society including:
Language – Tackling everyday ageist language used to talk about older and younger people.
Cities – Making our cities more accessible and age-friendly.
Services – Promote independence by making financial and technology services easier, safer and fairer to use.
Ageism effects all of us – whether we are young, old, or somewhere in between. Ageism is a broad issue throughout the UK that exists in many different areas in society. In this webinar we will discuss this issue and the different areas of ageism that exist within our society including: Language – Tackling everyday ageist language used to talk about older and younger people. Cities – Making our cities more accessible and age-friendly. Services – Promote independence by making financial and technology services easier, safer and fairer to use.
Putting Fuel on the Fire - Advocacy in the NorthCitizen Network
Simon Duffy gave this talk at the North East and Cumbria Advocacy Conference on 30th March 2017 in Newcastle. He explores why citizenship matters and what are the challenges we face in the years ahead.
Ageism effects all of us – whether we are young, old, or somewhere in between. Ageism is a broad issue throughout the UK that exists in many different areas in society. In this webinar we will discuss this issue and the different areas of ageism that exist within our society including:
Language – Tackling everyday ageist language used to talk about older and younger people.
Cities – Making our cities more accessible and age-friendly.
Services – Promote independence by making financial and technology services easier, safer and fairer to use.
Ageism effects all of us – whether we are young, old, or somewhere in between. Ageism is a broad issue throughout the UK that exists in many different areas in society. In this webinar we will discuss this issue and the different areas of ageism that exist within our society including: Language – Tackling everyday ageist language used to talk about older and younger people. Cities – Making our cities more accessible and age-friendly. Services – Promote independence by making financial and technology services easier, safer and fairer to use.
ILC-UK Future of Ageing Presentation Slides - 09Nov16 ILC- UK
On Wednesday 9th November 2016, ILC-UK held it's second annual future of Ageing conference.
We welcomed over 180 delegates made up of business leaders; charity sector experts; public sector decision makers; local authority staff; academics; and senior journalists.
The one day conference was chaired by Baroness Slly Greengross OBE and Lawrence Churchill CBE, and we heard from the following speakers:
- Dr Islene Araujo de Carvalho, Senior Policy and Strategy Adviser, Department of Ageing and Life Course, WHO
- John Cridland CBE, Head of the Independent State Pension Age Review
- The Rt Rev. and the Rt Hon. the Lord Carey of Clifton, Archbishop of Canterbury 1991-2002
- Ben Franklin, Head of Economics of an Ageing Society, ILC-UK
- Professor Sarah Harper, Director, Oxford Institute of Population Ageing
- Dwayne Johnson, Director of Social Care and Health at Sefton Metropolitan Borough Council
- Dr Margaret McCartney, Author and Broadcaster
- John Pullinger CB, National Statistician, UK Statistics Authority
- David Sinclair, Director, ILC-UK
- Jonathan Stevens, Senior Vice President, Thought Leadership, AARP
- Linda Woodall, Director of Life Insurance and Financial Advice, and sponsor of the Ageing Population project, Financial Conduct Authority
The London Assembly Health Committee has investigated the quality of care people receive at the end of their life. Does good end of life care depend on your age, whether you live alone, your diagnosis or economic status? Read the digital report's finding and recommendations.
Careif Global Essay: Ageing: The health, social, economic and cultural challenges of the 21st Century: a new demographic reality
You are invited to submit, in open competition, an original essay on ‘Ageing: the health, social and economic challenges of the 21st Century’ and to explore its demographic reality, cultural meaning, socio-economic context, and its association with the illnesses of old age. The essay should include an incisive and synoptic literature review, focusing on improving knowledge about the ethno-aetiology of ageing together with clues to prepare health providers and societies to meet the specific needs of older populations. This could include training for health professionals on old-age care; preventing and managing age-associated chronic diseases; designing sustainable policies on long-term and palliative care; and developing age-friendly services and settings. An exploration of contrasts between low income and high income countries are of particular interest and are very welcome.
http://careif.org/careif-global-essay-ageing-the-health-social-economic-and-cultural-challenges-of-the-21st-century-a-new-demographic-reality
On the 24th November 2015, we held our first annual conference on 'The Future of Ageing'.
During this full day conference we painted a picture of the future of ageing and explored the challenges and opportunities ahead. Through our unique lifecourse focus we explored the potential impact of ageing not just on today’s older population, but also on tomorrows.
We heard presentations from:
- Steven Baxter (Partner, Hymans Robertson);
- Lord Filkin (Chair of the Centre for Ageing Better and Chair of the House of Lords Committee on Public Service and Demographic Change);
- Lord Willetts (Executive Chair at Resolution Foundation, and former Minister of State [Department for Business, Innovation and Skills]);
- Paul Johnson (Director, Institute for Fiscal Studies);
- Baroness Altmann (Minister for Pensions);
- Professor Jane Elliott (Chief Executive, Economic and Social Research Council);
- Professor Sir Mark Walport (Government Chief Scientific Adviser [GCSA] and Head of the Government Office for Science);
- Jim Boyd (Director of Corporate Affairs, Partnership);
- Elaine Draper (Director, Accessibility & Inclusion, Barclays);
- Mario Ambrosi (Head of Communications and Public Affairs, Anchor);
- Baroness Kay Andrews (Member of the House of Lords Built Environment Committee, Former Parliamentary Under-Secretary (Department for Communities and Local Government) 2006-2009);
- Professor Ian Philp (Deputy Medical Director for Older People’s Care, Heart of England NHS Foundation Trust).
The conference was chaired by Baroness Sally Greengross (Chief Executive, ILC-UK) and Lawrence Churchill (Trustee, ILC-UK).
The global challenge of achieving citizenship for allCitizen Network
Dr Simon Duffy, at the Manawanui International Conference on self-direction, argues that we can work together to advance citizenship for all. He outlines the place that self-directed support has had in advancing citizenship, but also warns of the danger of consumerism. He explores the growing threats to citizenship from scapegoating and meritocracy. He launched an international membership cooperative - Citizen Network.
The best job in the world: practising public health, past, present, future John Middleton
Presentation to University of Maastricht, International Masters in Public Health leadership and management course, December 14th 2018. 181214 middletonj maastricht
An invited presentation to the The Compassion and Social Justice Lecture Series on Courageous Leadership in a Crisis
"This event explores the courage required when leading in a crisis and making important decisions without precedence. Given the global impact of COVID, leaders are being tested daily. Hear perspectives from two global leaders and learn from their courageous leadership during the historical HIV/AIDS crisis and the more current COVID pandemic."
Speakers:https://beholdvancouver.org/events/courageous-leadership-in-a-crisis
CILIP Cymru Wales Conference 2019: Making loneliness everyone’s businessCILIP
Claire O'Shea's presentation:
The Campaign to End Loneliness was formed in 2011 in response to the growing problem of loneliness in our communities. Since then they have gathered an enormous amount of evidence and research as to what the causes are and what some of the solutions might be. Libraries and public spaces play a vital role in communities, particularly as the high strtteet struggles. Arts and culture are also fundamental interest in a lot of people’s lives, keeping them resilient and linked in with communities of interest. Campaign to End Loneliness will take you through their work and what you might be able to do to end loneliness in your roles.
ILC-UK Future of Ageing Presentation Slides - 09Nov16 ILC- UK
On Wednesday 9th November 2016, ILC-UK held it's second annual future of Ageing conference.
We welcomed over 180 delegates made up of business leaders; charity sector experts; public sector decision makers; local authority staff; academics; and senior journalists.
The one day conference was chaired by Baroness Slly Greengross OBE and Lawrence Churchill CBE, and we heard from the following speakers:
- Dr Islene Araujo de Carvalho, Senior Policy and Strategy Adviser, Department of Ageing and Life Course, WHO
- John Cridland CBE, Head of the Independent State Pension Age Review
- The Rt Rev. and the Rt Hon. the Lord Carey of Clifton, Archbishop of Canterbury 1991-2002
- Ben Franklin, Head of Economics of an Ageing Society, ILC-UK
- Professor Sarah Harper, Director, Oxford Institute of Population Ageing
- Dwayne Johnson, Director of Social Care and Health at Sefton Metropolitan Borough Council
- Dr Margaret McCartney, Author and Broadcaster
- John Pullinger CB, National Statistician, UK Statistics Authority
- David Sinclair, Director, ILC-UK
- Jonathan Stevens, Senior Vice President, Thought Leadership, AARP
- Linda Woodall, Director of Life Insurance and Financial Advice, and sponsor of the Ageing Population project, Financial Conduct Authority
The London Assembly Health Committee has investigated the quality of care people receive at the end of their life. Does good end of life care depend on your age, whether you live alone, your diagnosis or economic status? Read the digital report's finding and recommendations.
Careif Global Essay: Ageing: The health, social, economic and cultural challenges of the 21st Century: a new demographic reality
You are invited to submit, in open competition, an original essay on ‘Ageing: the health, social and economic challenges of the 21st Century’ and to explore its demographic reality, cultural meaning, socio-economic context, and its association with the illnesses of old age. The essay should include an incisive and synoptic literature review, focusing on improving knowledge about the ethno-aetiology of ageing together with clues to prepare health providers and societies to meet the specific needs of older populations. This could include training for health professionals on old-age care; preventing and managing age-associated chronic diseases; designing sustainable policies on long-term and palliative care; and developing age-friendly services and settings. An exploration of contrasts between low income and high income countries are of particular interest and are very welcome.
http://careif.org/careif-global-essay-ageing-the-health-social-economic-and-cultural-challenges-of-the-21st-century-a-new-demographic-reality
On the 24th November 2015, we held our first annual conference on 'The Future of Ageing'.
During this full day conference we painted a picture of the future of ageing and explored the challenges and opportunities ahead. Through our unique lifecourse focus we explored the potential impact of ageing not just on today’s older population, but also on tomorrows.
We heard presentations from:
- Steven Baxter (Partner, Hymans Robertson);
- Lord Filkin (Chair of the Centre for Ageing Better and Chair of the House of Lords Committee on Public Service and Demographic Change);
- Lord Willetts (Executive Chair at Resolution Foundation, and former Minister of State [Department for Business, Innovation and Skills]);
- Paul Johnson (Director, Institute for Fiscal Studies);
- Baroness Altmann (Minister for Pensions);
- Professor Jane Elliott (Chief Executive, Economic and Social Research Council);
- Professor Sir Mark Walport (Government Chief Scientific Adviser [GCSA] and Head of the Government Office for Science);
- Jim Boyd (Director of Corporate Affairs, Partnership);
- Elaine Draper (Director, Accessibility & Inclusion, Barclays);
- Mario Ambrosi (Head of Communications and Public Affairs, Anchor);
- Baroness Kay Andrews (Member of the House of Lords Built Environment Committee, Former Parliamentary Under-Secretary (Department for Communities and Local Government) 2006-2009);
- Professor Ian Philp (Deputy Medical Director for Older People’s Care, Heart of England NHS Foundation Trust).
The conference was chaired by Baroness Sally Greengross (Chief Executive, ILC-UK) and Lawrence Churchill (Trustee, ILC-UK).
The global challenge of achieving citizenship for allCitizen Network
Dr Simon Duffy, at the Manawanui International Conference on self-direction, argues that we can work together to advance citizenship for all. He outlines the place that self-directed support has had in advancing citizenship, but also warns of the danger of consumerism. He explores the growing threats to citizenship from scapegoating and meritocracy. He launched an international membership cooperative - Citizen Network.
The best job in the world: practising public health, past, present, future John Middleton
Presentation to University of Maastricht, International Masters in Public Health leadership and management course, December 14th 2018. 181214 middletonj maastricht
An invited presentation to the The Compassion and Social Justice Lecture Series on Courageous Leadership in a Crisis
"This event explores the courage required when leading in a crisis and making important decisions without precedence. Given the global impact of COVID, leaders are being tested daily. Hear perspectives from two global leaders and learn from their courageous leadership during the historical HIV/AIDS crisis and the more current COVID pandemic."
Speakers:https://beholdvancouver.org/events/courageous-leadership-in-a-crisis
CILIP Cymru Wales Conference 2019: Making loneliness everyone’s businessCILIP
Claire O'Shea's presentation:
The Campaign to End Loneliness was formed in 2011 in response to the growing problem of loneliness in our communities. Since then they have gathered an enormous amount of evidence and research as to what the causes are and what some of the solutions might be. Libraries and public spaces play a vital role in communities, particularly as the high strtteet struggles. Arts and culture are also fundamental interest in a lot of people’s lives, keeping them resilient and linked in with communities of interest. Campaign to End Loneliness will take you through their work and what you might be able to do to end loneliness in your roles.
Apresentação feita por Mariana Machado dos Santos Pereira no II Seminário da Planificação da Atenção à Saúde, realizado em Brasília, nos dias 10 e 11 de dezembro de 2019.
Apresentação feita por Marisa Araujo Costa no II Seminário da Planificação da Atenção à Saúde realizado em Brasília, nos dias 10 e 11 de dezembro de 2019.
Apresentação feita por PlanificaSUS-PE no II Seminário da Planificação da Atenção à Saúde, realizado em Brasília, nos dias 10 e 11 de dezembro de 2019.
Apresentação feita por Jackeline da Rocha Vasques
no II Seminário da Planificação da Atenção à Saúde, realizado em Brasília, nos dias 10 e 11 de dezembro de 2019.
Apresentação feita por Gracielen Cristina Milomes Alves no II Seminário da Planificação da Atenção à Saúde, realizado em Brasília, nos dias 10 e 11 de dezembro de 2019.
Apresentação feita por Gisleine Lima da Silva
no II Seminário da Planificação da Atenção à Saúde, realizado em Brasília, nos dias 10 e 11 de dezembro de 2019.
Apresentação feita por Eliziane Brandão Leite, no II Seminário da Planificação da Atenção à Saúde, realizado em Brasília, nos dias 10 e 11 de dezembro de 2019.
Apresentação feita por Érika Souza e Edna Ferreira Santos, no II Seminário da Planificação da Atenção à Saúde, realizado em Brasília, nos dias 10 e 11 de dezembro de 2019.
Apresentação feita por Érica Correia Garcia no II Seminário da Planificação da Atenção à Saúde, realizado em Brasília, nos dias 10 e 11 de novembro de 2019.
Apresentação feita por Erika Cavalcanti de Oliveira, no II Seminário da Planificação da Atenção à Saúde, realizado em Brasília, nos dias 10 e 11 de dezembro de 2019.
Apresentação feita por Anna Otilia Paiva Ferreira no II Seminário da Planificação da Atenção à Saúde, realizado em Brasília, nos dias 10 e 11 de dezembro de 2019.
Apresentação feita por Hermelinda C. Pedrosa, no no II Seminário da Planificação da Atenção à Saúde, realizado em Brasília, nos dias 10 e 11 de dezembro de 2019.
Apresentação feita pela Sociedade Brasileira de Pediatria, no II Seminário da Planificação da Atenção à Saúde, realizado em Brasília, nos dias 10 e 11 de dezembro de 2019.
Apresentação feita pelo consultor do Conass, Marco Antônio, no II Seminário da Planificação da Atenção à Saúde, realizado em Brasília, nos dias 10 e 11 de dezembro de 2019.
Apresentação feita por Lúcio Flávio de Faria e Silva, promotor de Justiça (Uberlândia/MG), no II Seminário da Planificação da Atenção à Saúde, realizado em Brasília, nos dias 10 e 11 de dezembro de 2019.
Apresentação feita pelo Antonio Borges Nunes Júnior – Promotor de Justiça (Timon/MA), no II Seminário da Planificação da Atenção à Saúde, realizado em Brasília, nos dias 10 e 11 de dezembro de 2019.
More from Conselho Nacional de Secretários de Saúde - CONASS (20)
HOT NEW PRODUCT! BIG SALES FAST SHIPPING NOW FROM CHINA!! EU KU DB BK substit...GL Anaacs
Contact us if you are interested:
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NEW HOT EUTYLONE WHITE CRYSTAL!!
5cl-adba precursor (semi finished )
5cl-adba raw materials
ADBB precursor (semi finished )
ADBB raw materials
APVP powder
5fadb/4f-adb
Jwh018 / Jwh210
Eutylone crystal
Protonitazene (hydrochloride) CAS: 119276-01-6
Flubrotizolam CAS: 57801-95-3
Metonitazene CAS: 14680-51-4
Payment terms: Western Union,MoneyGram,Bitcoin or USDT.
Deliver Time: Usually 7-15days
Shipping method: FedEx, TNT, DHL,UPS etc.Our deliveries are 100% safe, fast, reliable and discreet.
Samples will be sent for your evaluation!If you are interested in, please contact me, let's talk details.
We specializes in exporting high quality Research chemical, medical intermediate, Pharmaceutical chemicals and so on. Products are exported to USA, Canada, France, Korea, Japan,Russia, Southeast Asia and other countries.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
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Reino Unido – Lessons from St. Christopher’s: what we are learning
1. Lessons from St. Christopher’s:
what we are learning
Professor Rob George MA MD FRCP FRCGP Hon
Medical Director
Cicely Saunders Institute King’s College London
“You matterbecauseyou areyou, and you
matteruntil the last momentof your life.
We will do all we can not only to help you
die peacefully,but also to live until you
die.”
DameCicelySaunders
Completing my life
well, not meeting
my death badly
2. CULTURE & PREJUDICE
HIV, & the disadvantaged dying
Beginnings of a Movement
COMPASSIONATE COMMUNITIES
Service development at scale
The UK’s Journey: from the best for one
to something for everyone?
Total Pain
The team approach
Completing lives well
Avoiding harms on the way
Capturing complexity
1967
1987
2000
2010
1891
3. 500 voluntary hospitals
were established in
England during the 12th
and 13th centuries.
Where things all began: buildings!
“for the man who is neither
curable nor incurable but
simply dying”.
(Colonel William Hoare 1891)
‘I want to give to the poor for love
what the rich can buy with money’
(Venerable Mary Aikenhead 1900)
The Mildmay Mission Hospital
1866-1970 ‘The fever Hospital’
1988 ‘The HIV Hospice’
Amidst a lot of suspicionCicely Saunders
1950’s 1967 St Christopher’s
Built
4. Focus on the individual The unloved,
the unlovable
and the
unlovely
You matter
because you are
you; you matter
to the very last
moment
We are not here
to help you die,
but to help you
live until you die
There is never
nothing
more that you
can do
http://endoflifestudies.academicblogs.co.uk/
early-origins-of-st-christophers-hospice/
5. 2030
Life expectancy:
85 years
Top causes of death:
Dementia /organ failure
multiple morbidity
Typical social context:
More lone-living – friends
& neighbours as carers
Disability before death:
Long-term frailty and
chronic impairment
A changing picture of dying
1900
Life expectancy:
47 years
Top cause of death:
childbirth
infection
accidents
Typical social context:
extended families
Disability before
death:
Not much
2018
Life expectancy:
80 years
Top cause of death:
Dementia
Heart disease
cancer
Typical social context:
Dispersed, smaller
families
Disability before death:
Months to many years
6. Rob George 2019
Clinical, financial and ethical imperatives:
frailty and multi-morbidity is our problem now
People die from
lives
Population-based
• No size will fit all
• What is the best
that you can do?
• Build capacity
• Collaborate
• Co-produce
• 83% of health
spending is in the
last year of life.
• Palliative care in
our communities
must double by
2040
• Most of our
dying popln are
old & frail
• The rest have
multi-morbidity
• People with
different diseases
have different
needs
7. Rob George 2019
“No problem can be solved from the same level
of consciousness that created it.
We must learn to see the world anew.”
Albert Einstein
Horizon Scanning
8. Challenges in the UK
the origins of the movement with
very strong local interests driven
often by particular deaths
The heavily medicalised model of
illness leads to people being seen as
pathologies and not people.
The expectations of the NHS &
social care is unsustainable
death is removed to institutions
a ‘service’ culture vs care culture -
done to rather than done with
Solutions in the UK
Death and dying is not special, but
universal
The Hospice Movement has been special
It is a ‘back to the future’ that is
needed
Community in terms of location or
common values eg faith
Social networks and individualism as
proxy for extended family
Local partnerships and co-production
(Confused) complexity, Consumerism,
Capacity, Change resistance
9. “I can make the last
stage of my life as good as
possible because everyone
works together confidently,
honestly and consistently
to help me and the people
who are important to me,
including my carer(s).”
Each person is seen as an individual01
Maximising comfort and wellbeing03
Each community is prepared to help06
All staff are prepared to care05
Each person gets fair access to care02
Care is coordinated04
National Approach
11. Implications for Hospices -an interdependent blend:
direct and indirect care support, skills development, education and engagement
IMPACTdirect &
Individual
indirect &
communal
RESOURCE
highest, most focused,
& least flexible
Lowest, most
adaptable & responsive
A resource to other
professionals/ services
Public support and education
Societal change
Innovation & influence
Service offerings
Direct
Care and
support
12. IT & Learning Hub, community partners
risk zone
Building is always risky
PERFORMANCE
TIME
One near collapse
Frailty
One success story
Heart Failure
Four developments
IT (ECHO)
Learning Hub
Compassionate
neighbours
Coach for care
Wellbeing project
New partnerships
FRAILTY
We did it our way …
HEART FAILURE
We learned our lesson
13. Rob George 2019
Frail elders, family and friends
GPs, palliative care, mental health and
allied health professionals, geriatricians
Social care, social workers, personal care
providers
Third sector: Age UK, Ageing Better,
Hospice UK
Academic collaborators
St Christopher’s
Age-attuned Hospice Care:
https://www.stchristophers.org.uk/wp-content/uploads/2018/10/Age-attuned-Hospice-care-document.pdf
National Institute of Health Programme Grant:
Defining needs, seeing what is available, developing
training programmes
14. 60 Care Homes
GP Communities of Practice
One Hospice
International partners (Premier)
Age attuned
palliative care:
Light touch
Re-enablement
Rapid response
Judy 75, good
neighbour to
Anna 43
>125,000 volunteers in the UK
contribute to hospice care.
25% of additional expenditure saved
17. A society in which citizens help each other through
the difficulties that arise as a result of death, dying
and loss
where death is seen as part of life
where planning for end of life is the norm
in which citizens feel confident to support their families,
friends and neighbours in times of serious illness or
bereavement
where medicine and healthcare can focus on doing what it
does best
o redressing challenging clinical problems
18. Sydenham site
51-59 Lawrie Park Road, Sydenham, London SE26 6DZ
Bromley site
Caritas House, Tregony Road, Orpington BR6 9XA
Telephone 020 8768 4500
Email info@stchristophers.org.uk
www.stchristophers.org.uk
#stchrishospice
St Christopher’s is a registered charity (210667) registered with the Fundraising Regulator