SlideShare a Scribd company logo
1 of 1
Download to read offline
Reaction Paper On Dengue
Dengue is the one of the most dangerous diseases in the world today. With over 50 million people
infected annually, the mosquito–borne virus has been identified by the World Health Organisation
(WHO) as a public health emergency of international concern. Despite the biomedical war on
Dengue, the disease has proven difficult to defeat. What is particularly dangerous about Dengue is
its alarming adaptability to the human immune system and antivirals, allowing it to evolve and
survive. Singapore, being in the South–East Asia and Western Pacific region which is home to over
70% of the world population plagued by the disease, is especially at risk to this unpredictable and
tenaciously resilient disease.
This, however, is set to change with the...show more content...
She and her team at the Genomic Institute of Singapore (GIS) has pioneered research into
applying NGS to Dengue virus, achieving a method to amplify the Dengue virus out of human
blood samples and subsequent NGS analysis, of which leads to many applications. To understand
this complex technology simply, sequencing can be imagined as arranging big basket of
nucleatides in order to make sense of each and all of them. Dengue, which is a virus composed of
10 000 base pairs, consists in each type a single mutation each time it replicates. This arises when
the virus folds in its protein form and its error–prone RNA–dependent RNA polymerase changes its
nucleic base to behave differently with a host factor, thereby making it more pathogenic. NGS is
therefore particularly useful as it allows scientists to pinpoint at which particular point there is such
a nucleotide variant, which is important epidemiological information on the highly mutagenic virus.
That position corresponds the method of translation for the virus, which is critical to the life cycle of
the virus and how it responds to selective pressure in the environment to change. By looking at base
changes, NGS ultimately enables scientists to track what the virus wants to do. This is essential
information then allows scientists start at developing many
Get more content on HelpWriting.net

More Related Content

Similar to Reaction Paper On Dengue

PNAS-2012-Schoggins-14610-5
PNAS-2012-Schoggins-14610-5PNAS-2012-Schoggins-14610-5
PNAS-2012-Schoggins-14610-5
Michael Feulner
 
IOSRPHR(www.iosrphr.org) IOSR Journal of Pharmacy
IOSRPHR(www.iosrphr.org) IOSR Journal of PharmacyIOSRPHR(www.iosrphr.org) IOSR Journal of Pharmacy
IOSRPHR(www.iosrphr.org) IOSR Journal of Pharmacy
iosrphr_editor
 
IOSRPHR(www.iosrphr.org) IOSR Journal of Pharmacy
IOSRPHR(www.iosrphr.org) IOSR Journal of PharmacyIOSRPHR(www.iosrphr.org) IOSR Journal of Pharmacy
IOSRPHR(www.iosrphr.org) IOSR Journal of Pharmacy
iosrphr_editor
 
Exploring the origin and potential for spread of the 2013 dengue outbreak in ...
Exploring the origin and potential for spread of the 2013 dengue outbreak in ...Exploring the origin and potential for spread of the 2013 dengue outbreak in ...
Exploring the origin and potential for spread of the 2013 dengue outbreak in ...
Yan'an Hou
 
Dengue 1214446525598008-8
Dengue 1214446525598008-8Dengue 1214446525598008-8
Dengue 1214446525598008-8
Chuan Yong
 
Microbiology hiv-yf
Microbiology   hiv-yfMicrobiology   hiv-yf
Microbiology hiv-yf
MBBS IMS MSU
 

Similar to Reaction Paper On Dengue (20)

PNAS-2012-Schoggins-14610-5
PNAS-2012-Schoggins-14610-5PNAS-2012-Schoggins-14610-5
PNAS-2012-Schoggins-14610-5
 
SEMINAR PRESENTATION-1-1.pptx
SEMINAR PRESENTATION-1-1.pptxSEMINAR PRESENTATION-1-1.pptx
SEMINAR PRESENTATION-1-1.pptx
 
Maghaleh viruse
Maghaleh viruseMaghaleh viruse
Maghaleh viruse
 
Gene sequencing and tb – a new age approach.pptx
Gene sequencing and tb – a new age approach.pptxGene sequencing and tb – a new age approach.pptx
Gene sequencing and tb – a new age approach.pptx
 
1.CRYPTOCOCCAL AND PCP.pptx
1.CRYPTOCOCCAL AND PCP.pptx1.CRYPTOCOCCAL AND PCP.pptx
1.CRYPTOCOCCAL AND PCP.pptx
 
Sharifi Burhanuddin.pptx
Sharifi Burhanuddin.pptxSharifi Burhanuddin.pptx
Sharifi Burhanuddin.pptx
 
IOSRPHR(www.iosrphr.org) IOSR Journal of Pharmacy
IOSRPHR(www.iosrphr.org) IOSR Journal of PharmacyIOSRPHR(www.iosrphr.org) IOSR Journal of Pharmacy
IOSRPHR(www.iosrphr.org) IOSR Journal of Pharmacy
 
IOSRPHR(www.iosrphr.org) IOSR Journal of Pharmacy
IOSRPHR(www.iosrphr.org) IOSR Journal of PharmacyIOSRPHR(www.iosrphr.org) IOSR Journal of Pharmacy
IOSRPHR(www.iosrphr.org) IOSR Journal of Pharmacy
 
Basic knowledge of_viral_metagenome_vanshika-varshney
Basic knowledge of_viral_metagenome_vanshika-varshneyBasic knowledge of_viral_metagenome_vanshika-varshney
Basic knowledge of_viral_metagenome_vanshika-varshney
 
Hiv
HivHiv
Hiv
 
Exploring the origin and potential for spread of the 2013 dengue outbreak in ...
Exploring the origin and potential for spread of the 2013 dengue outbreak in ...Exploring the origin and potential for spread of the 2013 dengue outbreak in ...
Exploring the origin and potential for spread of the 2013 dengue outbreak in ...
 
41579_2021_Article_536.pdf
41579_2021_Article_536.pdf41579_2021_Article_536.pdf
41579_2021_Article_536.pdf
 
YOGA AND COMPLEMENTARY THERAPIES FOR HIV
YOGA AND COMPLEMENTARY THERAPIES FOR HIVYOGA AND COMPLEMENTARY THERAPIES FOR HIV
YOGA AND COMPLEMENTARY THERAPIES FOR HIV
 
Bovine tuberculosis: Occupational hazard in Abattoir workers
Bovine tuberculosis: Occupational hazard in Abattoir workersBovine tuberculosis: Occupational hazard in Abattoir workers
Bovine tuberculosis: Occupational hazard in Abattoir workers
 
Sigma Xi Powerpoint Presentation
Sigma Xi Powerpoint PresentationSigma Xi Powerpoint Presentation
Sigma Xi Powerpoint Presentation
 
NGS for Infectious Disease Diagnostics: An Opportunity for Growth
NGS for Infectious Disease Diagnostics: An Opportunity for Growth NGS for Infectious Disease Diagnostics: An Opportunity for Growth
NGS for Infectious Disease Diagnostics: An Opportunity for Growth
 
CNS Iinfection dengue, Teaching Slides, Dr M D Mohire, Kolhapur, Maharashtra,...
CNS Iinfection dengue, Teaching Slides, Dr M D Mohire, Kolhapur, Maharashtra,...CNS Iinfection dengue, Teaching Slides, Dr M D Mohire, Kolhapur, Maharashtra,...
CNS Iinfection dengue, Teaching Slides, Dr M D Mohire, Kolhapur, Maharashtra,...
 
8
88
8
 
Dengue 1214446525598008-8
Dengue 1214446525598008-8Dengue 1214446525598008-8
Dengue 1214446525598008-8
 
Microbiology hiv-yf
Microbiology   hiv-yfMicrobiology   hiv-yf
Microbiology hiv-yf
 

More from College Paper Writers The University of Oklahoma Health Sciences Center

Jeremy Rifkin Enemies Of Promise
Jeremy Rifkin Enemies Of PromiseJeremy Rifkin Enemies Of Promise
The Advantages Of Debate
The Advantages Of DebateThe Advantages Of Debate
Summary Of What Is Education For By David Orr
Summary Of What Is Education For By David OrrSummary Of What Is Education For By David Orr
USF Job Analysis
USF Job AnalysisUSF Job Analysis
Historical And Cultural Values Of Heritage
Historical And Cultural Values Of HeritageHistorical And Cultural Values Of Heritage
Misinformation And False Memory Essay
Misinformation And False Memory EssayMisinformation And False Memory Essay
Advantages And Disadvantages Of Electronic Media
Advantages And Disadvantages Of Electronic MediaAdvantages And Disadvantages Of Electronic Media
Advantages And Disadvantages Of Electronic Media
College Paper Writers The University of Oklahoma Health Sciences Center
 
Persuasive Essay On Black History Month
Persuasive Essay On Black History MonthPersuasive Essay On Black History Month
How Important Was The Battle Of Gallipoli
How Important Was The Battle Of GallipoliHow Important Was The Battle Of Gallipoli

More from College Paper Writers The University of Oklahoma Health Sciences Center (13)

Workplace Diversity Report
Workplace Diversity ReportWorkplace Diversity Report
Workplace Diversity Report
 
Illegal Immigrants And Border Security Essay
Illegal Immigrants And Border Security EssayIllegal Immigrants And Border Security Essay
Illegal Immigrants And Border Security Essay
 
Infection Control
Infection ControlInfection Control
Infection Control
 
Reflection On Summative Assessment
Reflection On Summative AssessmentReflection On Summative Assessment
Reflection On Summative Assessment
 
Jeremy Rifkin Enemies Of Promise
Jeremy Rifkin Enemies Of PromiseJeremy Rifkin Enemies Of Promise
Jeremy Rifkin Enemies Of Promise
 
The Advantages Of Debate
The Advantages Of DebateThe Advantages Of Debate
The Advantages Of Debate
 
Summary Of What Is Education For By David Orr
Summary Of What Is Education For By David OrrSummary Of What Is Education For By David Orr
Summary Of What Is Education For By David Orr
 
USF Job Analysis
USF Job AnalysisUSF Job Analysis
USF Job Analysis
 
Historical And Cultural Values Of Heritage
Historical And Cultural Values Of HeritageHistorical And Cultural Values Of Heritage
Historical And Cultural Values Of Heritage
 
Misinformation And False Memory Essay
Misinformation And False Memory EssayMisinformation And False Memory Essay
Misinformation And False Memory Essay
 
Advantages And Disadvantages Of Electronic Media
Advantages And Disadvantages Of Electronic MediaAdvantages And Disadvantages Of Electronic Media
Advantages And Disadvantages Of Electronic Media
 
Persuasive Essay On Black History Month
Persuasive Essay On Black History MonthPersuasive Essay On Black History Month
Persuasive Essay On Black History Month
 
How Important Was The Battle Of Gallipoli
How Important Was The Battle Of GallipoliHow Important Was The Battle Of Gallipoli
How Important Was The Battle Of Gallipoli
 

Recently uploaded

Activity 01 - Artificial Culture (1).pdf
Activity 01 - Artificial Culture (1).pdfActivity 01 - Artificial Culture (1).pdf
Activity 01 - Artificial Culture (1).pdf
ciinovamais
 
The basics of sentences session 2pptx copy.pptx
The basics of sentences session 2pptx copy.pptxThe basics of sentences session 2pptx copy.pptx
The basics of sentences session 2pptx copy.pptx
heathfieldcps1
 

Recently uploaded (20)

Z Score,T Score, Percential Rank and Box Plot Graph
Z Score,T Score, Percential Rank and Box Plot GraphZ Score,T Score, Percential Rank and Box Plot Graph
Z Score,T Score, Percential Rank and Box Plot Graph
 
Mattingly "AI & Prompt Design: The Basics of Prompt Design"
Mattingly "AI & Prompt Design: The Basics of Prompt Design"Mattingly "AI & Prompt Design: The Basics of Prompt Design"
Mattingly "AI & Prompt Design: The Basics of Prompt Design"
 
BAG TECHNIQUE Bag technique-a tool making use of public health bag through wh...
BAG TECHNIQUE Bag technique-a tool making use of public health bag through wh...BAG TECHNIQUE Bag technique-a tool making use of public health bag through wh...
BAG TECHNIQUE Bag technique-a tool making use of public health bag through wh...
 
Sanyam Choudhary Chemistry practical.pdf
Sanyam Choudhary Chemistry practical.pdfSanyam Choudhary Chemistry practical.pdf
Sanyam Choudhary Chemistry practical.pdf
 
Student login on Anyboli platform.helpin
Student login on Anyboli platform.helpinStudent login on Anyboli platform.helpin
Student login on Anyboli platform.helpin
 
Disha NEET Physics Guide for classes 11 and 12.pdf
Disha NEET Physics Guide for classes 11 and 12.pdfDisha NEET Physics Guide for classes 11 and 12.pdf
Disha NEET Physics Guide for classes 11 and 12.pdf
 
The Most Excellent Way | 1 Corinthians 13
The Most Excellent Way | 1 Corinthians 13The Most Excellent Way | 1 Corinthians 13
The Most Excellent Way | 1 Corinthians 13
 
IGNOU MSCCFT and PGDCFT Exam Question Pattern: MCFT003 Counselling and Family...
IGNOU MSCCFT and PGDCFT Exam Question Pattern: MCFT003 Counselling and Family...IGNOU MSCCFT and PGDCFT Exam Question Pattern: MCFT003 Counselling and Family...
IGNOU MSCCFT and PGDCFT Exam Question Pattern: MCFT003 Counselling and Family...
 
Paris 2024 Olympic Geographies - an activity
Paris 2024 Olympic Geographies - an activityParis 2024 Olympic Geographies - an activity
Paris 2024 Olympic Geographies - an activity
 
Holdier Curriculum Vitae (April 2024).pdf
Holdier Curriculum Vitae (April 2024).pdfHoldier Curriculum Vitae (April 2024).pdf
Holdier Curriculum Vitae (April 2024).pdf
 
Activity 01 - Artificial Culture (1).pdf
Activity 01 - Artificial Culture (1).pdfActivity 01 - Artificial Culture (1).pdf
Activity 01 - Artificial Culture (1).pdf
 
fourth grading exam for kindergarten in writing
fourth grading exam for kindergarten in writingfourth grading exam for kindergarten in writing
fourth grading exam for kindergarten in writing
 
Interactive Powerpoint_How to Master effective communication
Interactive Powerpoint_How to Master effective communicationInteractive Powerpoint_How to Master effective communication
Interactive Powerpoint_How to Master effective communication
 
APM Welcome, APM North West Network Conference, Synergies Across Sectors
APM Welcome, APM North West Network Conference, Synergies Across SectorsAPM Welcome, APM North West Network Conference, Synergies Across Sectors
APM Welcome, APM North West Network Conference, Synergies Across Sectors
 
9548086042 for call girls in Indira Nagar with room service
9548086042  for call girls in Indira Nagar  with room service9548086042  for call girls in Indira Nagar  with room service
9548086042 for call girls in Indira Nagar with room service
 
INDIA QUIZ 2024 RLAC DELHI UNIVERSITY.pptx
INDIA QUIZ 2024 RLAC DELHI UNIVERSITY.pptxINDIA QUIZ 2024 RLAC DELHI UNIVERSITY.pptx
INDIA QUIZ 2024 RLAC DELHI UNIVERSITY.pptx
 
Arihant handbook biology for class 11 .pdf
Arihant handbook biology for class 11 .pdfArihant handbook biology for class 11 .pdf
Arihant handbook biology for class 11 .pdf
 
social pharmacy d-pharm 1st year by Pragati K. Mahajan
social pharmacy d-pharm 1st year by Pragati K. Mahajansocial pharmacy d-pharm 1st year by Pragati K. Mahajan
social pharmacy d-pharm 1st year by Pragati K. Mahajan
 
The basics of sentences session 2pptx copy.pptx
The basics of sentences session 2pptx copy.pptxThe basics of sentences session 2pptx copy.pptx
The basics of sentences session 2pptx copy.pptx
 
Presentation by Andreas Schleicher Tackling the School Absenteeism Crisis 30 ...
Presentation by Andreas Schleicher Tackling the School Absenteeism Crisis 30 ...Presentation by Andreas Schleicher Tackling the School Absenteeism Crisis 30 ...
Presentation by Andreas Schleicher Tackling the School Absenteeism Crisis 30 ...
 

Reaction Paper On Dengue

  • 1. Reaction Paper On Dengue Dengue is the one of the most dangerous diseases in the world today. With over 50 million people infected annually, the mosquito–borne virus has been identified by the World Health Organisation (WHO) as a public health emergency of international concern. Despite the biomedical war on Dengue, the disease has proven difficult to defeat. What is particularly dangerous about Dengue is its alarming adaptability to the human immune system and antivirals, allowing it to evolve and survive. Singapore, being in the South–East Asia and Western Pacific region which is home to over 70% of the world population plagued by the disease, is especially at risk to this unpredictable and tenaciously resilient disease. This, however, is set to change with the...show more content... She and her team at the Genomic Institute of Singapore (GIS) has pioneered research into applying NGS to Dengue virus, achieving a method to amplify the Dengue virus out of human blood samples and subsequent NGS analysis, of which leads to many applications. To understand this complex technology simply, sequencing can be imagined as arranging big basket of nucleatides in order to make sense of each and all of them. Dengue, which is a virus composed of 10 000 base pairs, consists in each type a single mutation each time it replicates. This arises when the virus folds in its protein form and its error–prone RNA–dependent RNA polymerase changes its nucleic base to behave differently with a host factor, thereby making it more pathogenic. NGS is therefore particularly useful as it allows scientists to pinpoint at which particular point there is such a nucleotide variant, which is important epidemiological information on the highly mutagenic virus. That position corresponds the method of translation for the virus, which is critical to the life cycle of the virus and how it responds to selective pressure in the environment to change. By looking at base changes, NGS ultimately enables scientists to track what the virus wants to do. This is essential information then allows scientists start at developing many Get more content on HelpWriting.net