The document discusses recommendations around face mask use during the COVID-19 pandemic. It notes that recommendations vary between countries and health authorities. While masks are recommended for healthcare workers and symptomatic individuals, guidance for general community use differs. Some discourage widespread public use due to supply concerns and lack of evidence of effectiveness, while others suggest vulnerable groups or those in crowded areas use masks. The document calls for rational, evidence-based recommendations on appropriate mask use that consider cultural norms and supply issues.
www.cebm.netoxford-covid-19 1 What is the.docxodiliagilby
www.cebm.net/oxford-covid-19/
1
What is the efficacy of standard face masks compared to respirator
masks in preventing COVID-type respiratory illnesses in primary
care staff?
Trish Greenhalgh and Xin Hui Chan, University of Oxford
Kamlesh Khunti, University of Leicester
Quentin Durand-Moreau and Sebastian Straube, University of Alberta, Canada
Declan Devane and Elaine Toomey, Evidence Synthesis Ireland and Cochrane Ireland
Anil Adisesh, University of Toronto, and St. Michael’s Hospital, Toronto, Canada
On behalf of the Oxford COVID-19 Evidence Service Team
Centre for Evidence-Based Medicine, Nuffield Department of Primary Care Health Sciences,
University of Oxford
23rd March 2020
Correspondence to [email protected]
Most real-world research comparing standard face masks with respirator masks has
been in the context of influenza or other relatively benign respiratory conditions and
based in hospitals. There are no published head-to-head trials of these interventions
in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection,
COVID-19, and no trials in primary or community care settings. Current guidance is
therefore based partly on indirect evidence – notably, from past influenza, SARS and
MERS outbreaks – as well as expert opinion and custom and practice.
Policy guidance from various bodies (e.g. Public Health England, WHO) emphasises
the need to assess the contagion risk of an encounter and use the recommended
combination of equipment for that situation. A respirator mask and other highly
effective PPE (eye protection, gloves, long-sleeved gown, used with good
donning/doffing technique) are needed to protect against small airborne particles in
aerosol-generating procedures (AGPs) such as intubation. For non-AGPs, there is
no evidence that respirator masks add value over standard masks when both are
used with recommended wider PPE measures.
A recent meta-analysis of standard v respirator (N95 or FFP) masks by the Chinese
Cochrane Centre included six RCTs with a total of 9171 participants with influenza-
like illnesses (including pandemic strains, seasonal influenza A or B viruses and
zoonotic viruses such as avian or swine influenza). There were no statistically
significant differences in their efficacy in preventing laboratory-confirmed influenza,
laboratory-confirmed respiratory viral infections, laboratory-confirmed respiratory
infection and influenza-like illness, but respirators appeared to protect against
bacterial colonization.
http://www.cebm.net/oxford-covid-19/
mailto:[email protected]
https://www.cebm.net/oxford-covid-19/
www.cebm.net/oxford-covid-19/
2
CONTEXT
Concerns have been raised about the limited personal protective equipment (PPE)
provided for UK primary and community care staff with some GP surgeries,
pharmacies and care homes having very limited provision. We were asked to find out
whether and in what circumstances standard m ...
www.cebm.net/oxford-covid-19/
1
What is the efficacy of standard face masks compared to respirator
masks in preventing COVID-type respiratory illnesses in primary
care staff?
Trish Greenhalgh and Xin Hui Chan, University of Oxford
Kamlesh Khunti, University of Leicester
Quentin Durand-Moreau and Sebastian Straube, University of Alberta, Canada
Declan Devane and Elaine Toomey, Evidence Synthesis Ireland and Cochrane Ireland
Anil Adisesh, University of Toronto, and St. Michael’s Hospital, Toronto, Canada
On behalf of the Oxford COVID-19 Evidence Service Team
Centre for Evidence-Based Medicine, Nuffield Department of Primary Care Health Sciences,
University of Oxford
23rd March 2020
Correspondence to [email protected]
Most real-world research comparing standard face masks with respirator masks has
been in the context of influenza or other relatively benign respiratory conditions and
based in hospitals. There are no published head-to-head trials of these interventions
in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection,
COVID-19, and no trials in primary or community care settings. Current guidance is
therefore based partly on indirect evidence – notably, from past influenza, SARS and
MERS outbreaks – as well as expert opinion and custom and practice.
Policy guidance from various bodies (e.g. Public Health England, WHO) emphasises
the need to assess the contagion risk of an encounter and use the recommended
combination of equipment for that situation. A respirator mask and other highly
effective PPE (eye protection, gloves, long-sleeved gown, used with good
donning/doffing technique) are needed to protect against small airborne particles in
aerosol-generating procedures (AGPs) such as intubation. For non-AGPs, there is
no evidence that respirator masks add value over standard masks when both are
used with recommended wider PPE measures.
A recent meta-analysis of standard v respirator (N95 or FFP) masks by the Chinese
Cochrane Centre included six RCTs with a total of 9171 participants with influenza-
like illnesses (including pandemic strains, seasonal influenza A or B viruses and
zoonotic viruses such as avian or swine influenza). There were no statistically
significant differences in their efficacy in preventing laboratory-confirmed influenza,
laboratory-confirmed respiratory viral infections, laboratory-confirmed respiratory
infection and influenza-like illness, but respirators appeared to protect against
bacterial colonization.
http://www.cebm.net/oxford-covid-19/
mailto:[email protected]
https://www.cebm.net/oxford-covid-19/
www.cebm.net/oxford-covid-19/
2
CONTEXT
Concerns have been raised about the limited personal protective equipment (PPE)
provided for UK primary and community care staff with some GP surgeries,
pharmacies and care homes having very limited provision. We were asked to find out
whether and in what circumstances standard m ...
www.cebm.netoxford-covid-19 1 What is the.docxodiliagilby
www.cebm.net/oxford-covid-19/
1
What is the efficacy of standard face masks compared to respirator
masks in preventing COVID-type respiratory illnesses in primary
care staff?
Trish Greenhalgh and Xin Hui Chan, University of Oxford
Kamlesh Khunti, University of Leicester
Quentin Durand-Moreau and Sebastian Straube, University of Alberta, Canada
Declan Devane and Elaine Toomey, Evidence Synthesis Ireland and Cochrane Ireland
Anil Adisesh, University of Toronto, and St. Michael’s Hospital, Toronto, Canada
On behalf of the Oxford COVID-19 Evidence Service Team
Centre for Evidence-Based Medicine, Nuffield Department of Primary Care Health Sciences,
University of Oxford
23rd March 2020
Correspondence to [email protected]
Most real-world research comparing standard face masks with respirator masks has
been in the context of influenza or other relatively benign respiratory conditions and
based in hospitals. There are no published head-to-head trials of these interventions
in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection,
COVID-19, and no trials in primary or community care settings. Current guidance is
therefore based partly on indirect evidence – notably, from past influenza, SARS and
MERS outbreaks – as well as expert opinion and custom and practice.
Policy guidance from various bodies (e.g. Public Health England, WHO) emphasises
the need to assess the contagion risk of an encounter and use the recommended
combination of equipment for that situation. A respirator mask and other highly
effective PPE (eye protection, gloves, long-sleeved gown, used with good
donning/doffing technique) are needed to protect against small airborne particles in
aerosol-generating procedures (AGPs) such as intubation. For non-AGPs, there is
no evidence that respirator masks add value over standard masks when both are
used with recommended wider PPE measures.
A recent meta-analysis of standard v respirator (N95 or FFP) masks by the Chinese
Cochrane Centre included six RCTs with a total of 9171 participants with influenza-
like illnesses (including pandemic strains, seasonal influenza A or B viruses and
zoonotic viruses such as avian or swine influenza). There were no statistically
significant differences in their efficacy in preventing laboratory-confirmed influenza,
laboratory-confirmed respiratory viral infections, laboratory-confirmed respiratory
infection and influenza-like illness, but respirators appeared to protect against
bacterial colonization.
http://www.cebm.net/oxford-covid-19/
mailto:[email protected]
https://www.cebm.net/oxford-covid-19/
www.cebm.net/oxford-covid-19/
2
CONTEXT
Concerns have been raised about the limited personal protective equipment (PPE)
provided for UK primary and community care staff with some GP surgeries,
pharmacies and care homes having very limited provision. We were asked to find out
whether and in what circumstances standard m ...
www.cebm.net/oxford-covid-19/
1
What is the efficacy of standard face masks compared to respirator
masks in preventing COVID-type respiratory illnesses in primary
care staff?
Trish Greenhalgh and Xin Hui Chan, University of Oxford
Kamlesh Khunti, University of Leicester
Quentin Durand-Moreau and Sebastian Straube, University of Alberta, Canada
Declan Devane and Elaine Toomey, Evidence Synthesis Ireland and Cochrane Ireland
Anil Adisesh, University of Toronto, and St. Michael’s Hospital, Toronto, Canada
On behalf of the Oxford COVID-19 Evidence Service Team
Centre for Evidence-Based Medicine, Nuffield Department of Primary Care Health Sciences,
University of Oxford
23rd March 2020
Correspondence to [email protected]
Most real-world research comparing standard face masks with respirator masks has
been in the context of influenza or other relatively benign respiratory conditions and
based in hospitals. There are no published head-to-head trials of these interventions
in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection,
COVID-19, and no trials in primary or community care settings. Current guidance is
therefore based partly on indirect evidence – notably, from past influenza, SARS and
MERS outbreaks – as well as expert opinion and custom and practice.
Policy guidance from various bodies (e.g. Public Health England, WHO) emphasises
the need to assess the contagion risk of an encounter and use the recommended
combination of equipment for that situation. A respirator mask and other highly
effective PPE (eye protection, gloves, long-sleeved gown, used with good
donning/doffing technique) are needed to protect against small airborne particles in
aerosol-generating procedures (AGPs) such as intubation. For non-AGPs, there is
no evidence that respirator masks add value over standard masks when both are
used with recommended wider PPE measures.
A recent meta-analysis of standard v respirator (N95 or FFP) masks by the Chinese
Cochrane Centre included six RCTs with a total of 9171 participants with influenza-
like illnesses (including pandemic strains, seasonal influenza A or B viruses and
zoonotic viruses such as avian or swine influenza). There were no statistically
significant differences in their efficacy in preventing laboratory-confirmed influenza,
laboratory-confirmed respiratory viral infections, laboratory-confirmed respiratory
infection and influenza-like illness, but respirators appeared to protect against
bacterial colonization.
http://www.cebm.net/oxford-covid-19/
mailto:[email protected]
https://www.cebm.net/oxford-covid-19/
www.cebm.net/oxford-covid-19/
2
CONTEXT
Concerns have been raised about the limited personal protective equipment (PPE)
provided for UK primary and community care staff with some GP surgeries,
pharmacies and care homes having very limited provision. We were asked to find out
whether and in what circumstances standard m ...
Top health officials have changed their minds about face mask guidance — but ...Dr Matt Boente MD
(CNN)First, health officials said we shouldn’t wear face masks. Then, they said we should. Now, many are saying we must wear masks if we want to protect the economy, reopen more schools and save tens of thousands of lives.”If we all wore face coverings for the next four, six, eight, 12 weeks across the nation, this virus transmission would stop,” said Dr. Robert Redfield, director of the Centers for Disease Control and Prevention
Corna virus detail And corona virus in pakistanEmaan Uppal
The 2019–20 coronavirus pandemic is a pandemic of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The disease was first identified in Wuhan, Hubei, China in December 2019Avoiding close contact with sick individuals; frequently washing hands with soap and water; not touching the eyes, nose, or mouth with unwashed hands; and practicing good respiratory hygiene.
Anesthesiologist’s Prospective on Self-protection, Therapy, and Managements i...asclepiuspdfs
During the beginnings of 2020, a virus has spread from China and caused a huge surge in severe acute respiratory cases globally. Due to the high contagiousness and anomalous course of severe acute respiratory syndrome coronavirus 2, caused by coronavirus disease, abbreviated as COVID-19, the World Health Organization (W.H.O) announced it as a pandemic and strict measurements were implemented to try and protect the vulnerable populations and those fighting on the frontline of this wave.[1] Scientific personnel all over the world began reviewing hundreds of articles published by scientific authors about the preexisting coronaviruses to assess the strain and pathogenesis of COVID-19 and explore possible effective therapies. At the beginning of the pandemic, the goal was clear: Support the immune system by using preexisting drugs such as antibiotics and antivirals to prevent superinfections and alleviate possible foreseen complications, in addition to the use of prophylactic vaccines in high-risk groups. Another therapy option was the use of convalescent sera, which is a passive antibody therapy used as prophylaxis.[2] In this review, we conclude the importance of adhering to the precautionary guidelines set by the W.H.O recommended for health care workers and the general population, as the most important factor for protection against further transmission of the virus. The extra respiratory manifestations of the virus will also be highlighted along with the therapy modalities that are already being used and the upcoming vaccines that will counteract the virus.
Causes of prolonged use of masks during Covid- 19 pandemic .pdfPubricahealthcare
Publica’s experts suggest that for the forthcoming adverse effects related to extended mask usage, frequent breaks, improved hydration and rest, skincare, and possibly newly built comfortable masks are recommended.
The world is witnessing an invasion from a new corona virus, which resulted in more than one million of deaths. Most of the sectors such industrial, economy, and tourism are facing a crisis, hence the workers in the field of medicine, considered to be the barrier to fight this invasion. This new virus seems to have two main transmission routes: direct and contact, which it will open a high chance of infection among professional health providers, especially, surgeons and dentists. Maxillofacial and dental surgeons, considered to be essential professional health experts that perform, multiple surgeries and dental procedures every day, consequently, these professions will exhibit a high risk of getting infected by Covid19, due to that, this review article aimed to discuss the possible ways that it may help in optimizing the level of infection control.
Anxiety, uncertainty, and resilience of medical students worldwide during the...Ahmad Ozair
The COVID-19 pandemic significantly impacted medical education worldwide. While healthcare professionals labored to ensure proper care for COVID-19 patients, medical students suffered from high rates of anxiety, uncertainty, burnout, and depressive symptoms. Whilst students in the pre-clinical phase of education faced disruption of didactic lectures and laboratory training, senior medical students faced uncertainty regarding their clinical rotations and internships, which are vital for practical exposure to healthcare. Several studies across the world demonstrated that clinical learning was significantly affected, with students in many countries completely cut off from in-person rotations. The disruption of the clinical curriculum coupled with a sense of failure to contribute at a time of significant need often led to despair. Reforms proposed and/or implemented by governments, medical advisory boards, medical schools, and other administrative bodies were felt to be insufficient by the medical student fraternity at large. Consequently, these students continue to face high rates of anxiety, depression, and a general sense of cynicism. In this student-authored perspective, we highlight the challenges faced by and the psychological impact on medical students directly or indirectly from the pandemic.
“A maior contribuição dos protocolos de mascaramento expandidos pode ser reduzir a transmissão da ansiedade”.
Na verdade, usando máscaras, você pode atrasar outras pessoas no desenvolvimento de anticorpos de memória para proteção duradoura contra a infecção viral, para que nossa sociedade possa voltar ao normal.
For decades, it has been acknowledged by the world’s premier health authorities that amid a pandemic, the functioning of society should be maintained, and human rights upheld. Governments and health organisations have at their disposal country-specific pandemic preparedness plans, as well as the World Health Organisation pandemic guidelines, which provide a roadmap outlining how to keep society functioning, while also mitigating the impact of a disease or virus.
In 2020, SARS-CoV-2 brought an almost–instantaneous rewriting of disease management principles as countries, with few exceptions, disregarded existing pandemic plans and replaced them with policies of ‘lockdown’.
There is no evidence that lockdowns have reduced mortality from Covid-19 and research is now revealing the devastation that lockdowns are causing, particularly in the developing world. In these draconian lockdown policies, we have also seen the biggest infringement on civil liberties in democratic countries during peacetime.
PANDA believes that, at this juncture, the science is quite clear on what key policy responses should be—or should have been. The cure should not be worse than the disease. It is critically important that societies are reopened, whilst protecting those who may be vulnerable to serious illness from SARS-CoV-2. Human agency must be upheld, and individuals should be empowered to make their own choices.
PANDA’s Protocol for Reopening Society builds upon existing pandemic frameworks and incorporates current scientific understanding of Covid-19, to provide a roadmap out of the damaging cycle of lockdowns.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
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Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
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Evaluation of antidepressant activity of clitoris ternatea in animals
Rational use of face masks in the COVID-19 pandemic
1. Comment
www.thelancet.com/respiratory Published online March 20, 2020 https://doi.org/10.1016/S2213-2600(20)30134-X 1
Since the outbreak of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), the virus that caused
coronavirus disease 2019 (COVID-19), the use of face
masks has become ubiquitous in China and other
Asian countries such as South Korea and Japan. Some
provinces and municipalities in China have enforced
compulsory face mask policies in public areas; however,
China’s national guideline has adopted a risk-based
approach in offering recommendations for using face
masks among health-care workers and the general
public. We compared face mask use recommendations
by different health authorities (panel). Despite the
consistency in the recommendation that symptomatic
individuals and those in health-care settings should use
face masks, discrepancies were observed in the general
public and community settings.1–8
For example, the US
Surgeon General advised against buying masks for use
by healthy people. One important reason to discourage
widespread use of face masks is to preserve limited
supplies for professional use in health-care settings.
Universal face mask use in the community has also been
discouraged with the argument that face masks provide
no effective protection against coronavirus infection.
However, there is an essential distinction between
absence of evidence and evidence of absence. Evidence
that face masks can provide effective protection against
respiratory infections in the community is scarce, as
acknowledged in recommendations from the UK and
Germany.7,8
However, face masks are widely used by
medical workers as part of droplet precautions when
caring for patients with respiratory infections. It would
be reasonable to suggest vulnerable individuals avoid
crowded areas and use surgical face masks rationally
when exposed to high-risk areas. As evidence suggests
COVID-19 could be transmitted before symptom onset,
community transmission might be reduced if everyone,
Rational use of face masks in the COVID-19 pandemic
Lancet Respir Med 2020
Published Online
March 20, 2020
https://doi.org/10.1016/
S2213-2600(20)30134-X
Sputnik/SciencePhotoLibrary
Panel: Recommendations on face mask use in community settings
WHO1
• Ifyou are healthy,you only needto wear a mask ifyou are
taking care of a person with suspected SARS-CoV-2 infection.
China2
• People at moderate risk* of infection: surgical or disposable
mask for medical use.
• People at low risk† of infection: disposable mask for medical
use.
• People at very low risk‡ of infection: do not have to wear a
mask or can wear non-medical mask (such as cloth mask).
Hong Kong3
• Surgical masks can prevent transmission of respiratory
viruses from people who are ill. It is essential for people who
are symptomatic (even if they have mild symptoms) to wear
a surgical mask.
• Wear a surgical mask when taking public transport or
staying in crowded places. It is important to wear a mask
properly and practice good hand hygiene before wearing
and after removing a mask.
Singapore4
• Wear a mask if you have respiratory symptoms, such as a
cough or runny nose.
Japan5
• The effectiveness of wearing a face mask to protect yourself
from contracting viruses is thought to be limited. If you
wear a face mask in confined, badly ventilated spaces, it
might help avoid catching droplets emitted from others but
if you are in an open-air environment, the use of face mask
is not very efficient.
USA6
• Centers for Disease Control and Prevention does not
recommend that people who are well wear a face mask
(including respirators) to protect themselves from
respiratory diseases, including COVID-19.
• US Surgeon General urged people onTwitter to stop buying
face masks.
UK7
• Face masks play a very important role in places such as
hospitals, but there is very little evidence of widespread
benefit for members of the public.
Germany8
• There is not enough evidenceto provethatwearing a surgical
mask significantly reduces a healthy person’s riskof becoming
infectedwhilewearing it.AccordingtoWHO,wearing a mask
in situationswhere it is not recommendedtodo so can create
a false senseof security because it might leadto neglecting
fundamental hygiene measures, such as proper hand hygiene.
*People at moderate risk of infection include those working in areas of high population
density (eg, hospitals, train stations), those have been or live with somebody who is
quarantined, and administrative staff, police, security, and couriers whose work is related to
COVID-19. †People at low risk of infection include those staying in areas of high population
density (eg, supermarket, shopping mall), who work indoors, who seek health care in
medical institutions (other than fever clinics), and gatherings of children aged 3–6years
and school students. ‡People at very low risk of infection include those who mostly stay at
home, who do outdoor activities, and who work or study in well-ventilated areas.
2. Comment
2 www.thelancet.com/respiratory Published online March 20, 2020 https://doi.org/10.1016/S2213-2600(20)30134-X
including people who have been infected but are
asymptomatic and contagious, wear face masks.
Recommendations on face masks vary across countries
and we have seen that the use of masks increases
substantially once local epidemics begin, including the
use of N95 respirators (without any other protective
equipment) in community settings. This increase in
use of face masks by the general public exacerbates
the global supply shortage of face masks, with prices
soaring,9
and risks supply constraints to frontline health-
care professionals. As a response, a few countries (eg,
Germany and South Korea) banned exportation of face
masks to prioritise local demand.10
WHO called for a 40%
increase in the production of protective equipment,
including face masks.9
Meanwhile, health authorities
should optimise face mask distribution to prioritise
the needs of frontline health-care workers and the
most vulnerable populations in communities who are
more susceptible to infection and mortality if infected,
including older adults (particularly those older than
65years) and people with underlying health conditions.
People in some regions (eg, Thailand, China, and
Japan) opted for makeshift alternatives or repeated
usage of disposable surgical masks. Notably, improper
use of face masks, such as not changing disposable
masks, could jeopardise the protective effect and even
increase the risk of infection.
Consideration should also be given to variations in
societal and cultural paradigms of mask usage. The
contrast between face mask use as hygienic practice
(ie, in many Asian countries) or as something only
people who are unwell do (ie, in European and North
American countries) has induced stigmatisation and
racial aggravations, for which further public education is
needed. One advantage of universal use of face masks is
that it prevents discrimination of individuals who wear
maskswhenunwell because everybody iswearing a mask.
It is time for governments and public health agencies
to make rational recommendations on appropriate
face mask use to complement their recommendations
on other preventive measures, such as hand hygiene.
WHO currently recommends that people should wear
face masks if they have respiratory symptoms or if they
are caring for somebody with symptoms. Perhaps it
would also be rational to recommend that people in
quarantine wear face masks if they need to leave home
for any reason, to prevent potential asymptomatic or
presymptomatic transmission. In addition, vulnerable
populations, such as older adults and those with
underlying medical conditions, should wear face masks if
available. Universal use of face masks could be considered
if supplies permit. In parallel, urgent research on the
duration of protection of face masks, the measures to
prolong life of disposable masks, and the invention on
reusable masks should be encouraged. Taiwan had the
foresight to create a large stockpile of face masks; other
countries or regions might now consider this as part of
future pandemic plans.
We declare no competing interests.
*Shuo Feng†, Chen Shen†, Nan Xia†,Wei Song, Mengzhen
Fan, Benjamin J Cowling
shuo.feng@paediatrics.ox.ac.uk
OxfordVaccine Group, University of Oxford, Oxford, OX3 7LE, UK (SF);
Department of Epidemiology and Biostatistics, Imperial College London,
London, UK (CS); School of Public Health, Li Ka Shing Faculty of Medicine,The
University of Hong Kong, Pokfulam, Hong Kong, Special Administrative Region,
China (NX, BJC); Department of Chemistry, University of Oxford, Oxford, UK
(MF); and Department of Economics and Related Studies, University ofYork,
York, UK (WS)
†Contributed equally.
Editorial note: the Lancet Group takes a neutral position with respect to
territorial claims in published maps and institutional affiliations.
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