Kanumuri Ramesh Reddy is seeking a position in synthetic organic chemistry. He holds a Ph.D. from the University of Hyderabad and conducted postdoctoral research at North Carolina State University. His experience includes synthesizing heterocycles and carbocycles using Baylis-Hillman reactions and developing one-pot syntheses of indene-spiro-oxindoles. He currently works as a senior research scientist developing synthetic processes and has publications in organic chemistry journals.
International Journal of Engineering and Science Invention (IJESI)inventionjournals
International Journal of Engineering and Science Invention (IJESI) is an international journal intended for professionals and researchers in all fields of computer science and electronics. IJESI publishes research articles and reviews within the whole field Engineering Science and Technology, new teaching methods, assessment, validation and the impact of new technologies and it will continue to provide information on the latest trends and developments in this ever-expanding subject. The publications of papers are selected through double peer reviewed to ensure originality, relevance, and readability. The articles published in our journal can be accessed online.
International Journal of Engineering and Science Invention (IJESI)inventionjournals
International Journal of Engineering and Science Invention (IJESI) is an international journal intended for professionals and researchers in all fields of computer science and electronics. IJESI publishes research articles and reviews within the whole field Engineering Science and Technology, new teaching methods, assessment, validation and the impact of new technologies and it will continue to provide information on the latest trends and developments in this ever-expanding subject. The publications of papers are selected through double peer reviewed to ensure originality, relevance, and readability. The articles published in our journal can be accessed online.
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Tunisia
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1. Kanumuri Ramesh Reddy
9618029435, Hyderabad
rameshkanumu@gmail.com
Objective: Seeking a suitable position in synthetic organic chemistry
I. Educational Qualifications:
Ph. D.; (2003-2009) School of Chemistry, University of Hyderabad, India,
Advisor:Professor D. Basavaiah, Title: “Synthesis of Heterocycles & Carbocycles
using Baylis-Hillman adducts and Synthesis of Indene-Spiro-Oxindoles using
tandem Prins and Friedel-Crafts reactions”
M. Sc. Organic Chemistry (1999-2001): Andhra University, Visakapatnam, A.P, India.
B. Sc. Mathematics, Physics, Chemistry (1996-1999): Andhra University, Visakapatnam,
A.P, India.
II. Research Experience:
Postdoctoral Research Associate (2010-2013): North Carolina State University, Raleigh NC,
United States. In the research group of Professor Jonathan S. Lindsey.“Synthesis of Lipophilic
and water-soluble bioconjugatable bacteriochlorins for artificial photosynthesis”
III. Research Scientist (2014-2015) in Sai Life Sciences process research and development.
IV. Presently working as a Senior Research Scientist-I in Sai Life Sciences from April 2015 in
process research and development (PR&D) until now.
Preparing project quotations for chemistry (CRAMs) works.
Weekly status updates to customers by power point slides and telecons.
Responsible for providing documented controlled synthetic process for CRAMS chemistry
molecules as requested by customers.
Preparing regular written and verbal reports for customers.
Designing retro synthetic routes for target molecules and executing their synthesis.
Analyzing the problems (particularly impurities structures determinations using different
NMR techniques etc.) during synthetic route and solving them independently.
V. Awards:
Awarded the 1st
Prize for 2010 Eli Lilly and Company Asia Outstanding Thesis Award.
Awarded CSIR–SRF (Counsil of Scientific and Industrial Research-Senior Research
Fellowship), during the period 2005 to 2008
1
2. Awarded CSIR–JRF (Counsil of Scientific and Industrial Research-Junior Research
Fellowship), during the period 2003 to 2005
VI. LIST OF PUBLICATIONS:
1. “Simple and One-pot Protocol for Synthesis of Indene-Spiro-Oxindoles Involving Tandem
Prins and Friedel-Crafts Reactions” D. Basavaiah and K. Ramesh Reddy Org. Lett.2007, 9,
57-60. (Impact factor 6.32)
2.“An Expedient, Facile and Simple One-pot Synthesis of 2-Methylenealkanoates and
Alkanenitriles from the Baylis-Hillman Bromides in Aqueous Media” D. Basavaiah, K.
Ramesh Reddy and N. Kumaragurubaran Nature Protocols 2007, 2, 2665-2676. (Impact
factor 7.78)
3.“Simple and One-pot Synthesis of Tri and Tetracyclic Frameworks Containing
[1,8]naphthyridin-2-one Moiety from the Baylis-Hillman Adducts” D. Basavaiah and K.
Ramesh Reddy Tetrahedron 2010, 66, 1215-1219.(Impact factor 2.81)
4. “Simple One-pot and Facile Synthesis of Angularly Fused [6 7 5] [6 7 6] [6 7 7] and [6 7]
Ring Systems Using Baylis-Hillman Acetates” D. Basavaiah, K. Aravindu, Katta S. Kumar
and K. Ramesh Reddy Eur. J. Org. Chem., 2010,1843-1848. (Impact factor 3.15)
5. “Biohybrid Photosynthetic Antenna Complexes for Enhanced Light-Harvesting”
Joseph W. Springer, Pamela S. Parkes-Loach, K. Ramesh Reddy, M. Krayer, J. Jiao, G. M.
Lee, D. M. Niedzwiedzki, M. A. Harris, C. Kirmaier, D. F. Bocian, J. S. Lindsey, D. Holten,
and P. A. Loach. J. Am. Chem. Soc. 2012, 134, 4589-4599. (Impact factor 11.44)
6. “Synthetic Bacteriochlorins with Integral Spiro-piperidine Motifs” K. Ramesh Reddy, E.
Lubian, M. P. Pavan, H-Je Kim, E. Yang, D. Holten, and J. S. Lindsey New. J. Chem., 2013,
37, 1157-1173. (Impact factor 3.15)
7. “Palette of Lipophilic Bioconjugatable Bacteriochlorins for Construction of Biohybrid Light-
Harvesting Architectures” K. Ramesh Reddy, J. Jiang, M. Krayer, M. A. Harris, J. W.
Springer, E. Yang, J. Jiao, D. M. Niedzwiedzki, D. Pandithavidana, P. S. Parkes-Loach, C.
Kirmaier, P. A. Loach, D. F. Bocian, D. Holten, and J. S. Lindsey Chemical Science, 2013, 4,
2036-2053. (Impact factor 8.60)
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3. 8. “Hydrophilic Tetracarboxy Bacteriochlorins for Photonics Applications” J. Jiang, P.
Vairaprakash, K. Ramesh Reddy, T. Sahin, M. P. Pavan, E. Lubian and J. S. Lindsey, Org.
Biomol. Chem., 2014, 12, 86. (Impact factor 3.56)
9. Amphiphilic, hydrophilic or hydrophobic synthetic bacteriochlorins in biohybrid light-
harvesting architectures: consideration of molecular designs. J. Jiang, K. Ramesh Reddy, M.
P. Pavan, E. Lubian, M. A. Harris, J. Jiao, D. M. Niedzwiedzki, C. Kirmaier, P. S. Parkes-
Loach, P. A. Loach, D. F. Bocian, D. Holten and J. S. Lindsey. Journal of Photo Synthesis
Research 2014, 122, 187-202. (Impact factor 3.15)
10. Synthetic bacteriochlorins bearing polar motifs (carboxylate, phosphonate, ammonium and a
short PEG). Water-solubilization, bioconjugation, and photophysical properties. J. Jiang, E.
Yang, K. Ramesh Reddy, D. M. Niedzwiedzki, C. Kirmaier, D. F. Bocian, D. Holten and J.
S. Lindsey. New. J. Chem., 2015, 39, 5694-5714. (Impact factor 3.18).
VII. POSTERS and PRESENTATIONS:
1. Poster: 4th
in-house symposium “Chemfest-2007” University of Hyderabad, Hyderabad
India, March2007. “Simple and one-pot protocol for synthesis of Indene-Spiro-
Oxindoles involving tandem Prins and Friedel-Crafts reactions” D. Basavaiah and K.
Ramesh Reddy.
2. Poster: June,2011PARC (Photosynthetic Antenna Research Center) Annual Meeting,
held at Washington University, ST. Louis. “Synthesis of Lipophilic, Wavelength-
Tunable, Bioconjugatable Bacteriochlorins”K. Ramesh Reddy, M. Krayer, and J. S.
Lindsey.
3. Poster: July, 2012, PARC (Photosynthetic Antenna Research Center) Annual Meeting,
held at Washington University, ST. Louis, “Bioconjugatable Bacteriochlorins for Use in
Biohybrid Light Harvesting Architectures” K. Ramesh Reddy, M. Krayer, M. P. Pavan,
E. Lubian and J. S. Lindsey.
4. Talk: 5th
Singapore India Collaborative & Cooperative Chemistry Symposium.
Hyderabad, India. Feb, 2009. on “Simple and one-pot protocol for synthesis of Indene-
Spiro-Oxindoles involving tandem Prins and Friedel-Crafts reactions”
5. Poster: 244th ACS National Meetingheld in Philadelphia, Pennsylvania, August,
2012. “Palette of Bioconjugatable Bacteriochlorins with Near-Infrared Absorption”K.
Ramesh Reddy, M. Krayer and J. S. Lindsey.
3
4. SKILLS and RESEARCH EXPERIENCE
Demonstrated capability to succeed in the diverse areas of scientific research in synthetic
organic chemistry, a broad working knowledge of modern synthetic chemistry, including
understanding of reaction mechanisms and awareness of current important trends and
developments reported in the recent and relevant literature. Particular evidence will be (i)
Understanding the previous research areas of the applicant’s; (ii) Independent
intellectual and practical contributions to previous research projects; (iii) Attributes can
be brought to bear on the present project
Well acquainted in planning sequential synthetic methods and strategic approaches for
the desired molecules. And proposing new reaction mechanisms
Strong background and extensive experience with the analytical (NMR, MALDI-MS &
HPLC) techniques.
Well versed with crystallization techniques and fair knowledge of X-ray crystal structure
solution and refinement at hands on.
Well versed in handling the air / moisture sensitive reagents.
Familiar with online database (Web of Knowledge, Chemical Abstracts& SciFinder).
Can coordinate well with colleagues/coworkers in a laboratory environment.
Well acquainted in planning synthetic schemes and strategic approaches for the desired
molecules.
Summary of Research Work
Ph. D. Thesis Work (2003-2009): Shool of Chemistry, University of Hyderabad, India Under
the guidence of Professor D. Basavaiah. Awarded the 1st
Prize for 2010 Eli Lilly and Company
Asia Outstanding Thesis Award.
Baylis-Hillman reaction has become a very popular carbon-carbon bond forming reaction and the
Baylis-Hillman adducts have been employed in various organic transformation methodologies
and also in the synthesis of various biologically active molecules and natural products. Our
research group has been working for the last several years, on various aspects of the Baylis-
Hillman reaction and has extensively used the Baylis-Hillman adducts in various organic
transformations. In continuation of our interest in expanding the scope of Baylis-Hillman adducts
4
5. as a novel source for organic transformations we have developed (1) asimple and one-pot
synthesis of benzo[b][1,8]naphthyridones from the Baylis-Hillman adducts. (2) We developed a
simple facile and multi-step, one-pot synthesis of quinoline derivatives from the Baylis-Hillman
adducts. (3) We have developed a simple synthesis of bicyclic frameworks containing
benzocycloheptane skeleton and tetracyclic-carbocyclic framework containing 6,7,6,6 ring
systems from the Baylis-Hillman addducts.
N N
H
O
R4
R3
R5
N N
H
O
R5
N Me
R4
R3
EWG2 EWG1
N Me
EWG2 EWG1
EWG
EWG3Me
R4
R3
R2
EWG
R4
R3
R2
OH
EWG = CN, COMe, CO2Me, CO2Et
EWG
OH (OAc)
R4
R3
R2
R1
R1 = H, NO2, R2 = H, OMe, R3 = H, OMe, R4 = H, Br, Cl,
OMe, OEt, OPropyl; R2, R3 = C4H4, R3, R4 = CH2O2,
R5 = H, Me
R5 = H, Me EWG1 = CO2Et, CO2Me
EWG2 = COPh, CO2Me
EWG1 = CO2Et, CO2Me
EWG2 = COPh, CO2Me
EWG = CO2Me, CO2Et
EWG3 = CO2H, CO2Et, CO2Me
EWG = CO2Me, CO2Et
(4) We have also develped simple and one-pot protocol for synthesis of indene-spiro-
oxindoles involving construction of two carbon-carbon bonds via tandem Prins and Friedel-
Crafts reactions.
5
6. Postdoctoral Research work (2010-2013): North Carolina State University (NCSU), Raleigh
NC, United States, in the research laboratory of Professor Jonathan S. Lindsey. “Synthesis of
Lipophilic and water-soluble bioconjugatable bacteriochlorins for artificial photosynthesis”
N HN
NNH
R
Ra
Rb
N OO
H
N
N
O
O
O
R = OMe
R = H
+
O
N
H
Rb
O2N
Ra
N HN
NNH
OMe
Ra
Rb
Ra
Rb
NH
N
O
O
O
Ra = H and Rb = H
Ra = Et and Rb = COOEt
or
OMe
OMe
N HN
NNH
OMe
N
H
O
CO2H
Ra = H and Rb = H
N HN
NNH
AcNN
H
O
I
Rb
Ra
Ra
Rb
Ra = Et and Rb = COOEt
or
N
O
Rc
N HN
NNH
N
N
Ra
Rb
Rb
Ra
Rd
Rd
N HN
NNH
R
N
N
Ra
Rb
Rb
Ra
I
I
R = OMe or R = H, OMe
Ra = Et and Rb = COOEt
R
Ra = Et and Rb = COOEt
Rd = H, Me, Ac, Ts
Ra
Rb
Ra
Ra = Rb = H
Ra = H, Et, Rb = H, COOEt, Br
Rc = Ts, Boc
R = H, OMe
References:
Professor Jonathan S. Lindsey Professor Deevi Basavaiah
Glaxo Distinguished University Professor School of Chemistry
Department of Chemistry University of Hyderabad
NC State University Hyderabad-5000046, AP, India
Raleigh, NC 27695-8204 Tel: +91-40-23010977 (R)
Tel: (919)-515-2940 +91-40-23134812 (O)
Fax: (919)-513-2830 Fax: +91-40-23012460
E-mail: jlindsey@ncsu.edu E-mail:dbsc@uohyd.ernet.in
6
7. Postdoctoral Research work (2010-2013): North Carolina State University (NCSU), Raleigh
NC, United States, in the research laboratory of Professor Jonathan S. Lindsey. “Synthesis of
Lipophilic and water-soluble bioconjugatable bacteriochlorins for artificial photosynthesis”
N HN
NNH
R
Ra
Rb
N OO
H
N
N
O
O
O
R = OMe
R = H
+
O
N
H
Rb
O2N
Ra
N HN
NNH
OMe
Ra
Rb
Ra
Rb
NH
N
O
O
O
Ra = H and Rb = H
Ra = Et and Rb = COOEt
or
OMe
OMe
N HN
NNH
OMe
N
H
O
CO2H
Ra = H and Rb = H
N HN
NNH
AcNN
H
O
I
Rb
Ra
Ra
Rb
Ra = Et and Rb = COOEt
or
N
O
Rc
N HN
NNH
N
N
Ra
Rb
Rb
Ra
Rd
Rd
N HN
NNH
R
N
N
Ra
Rb
Rb
Ra
I
I
R = OMe or R = H, OMe
Ra = Et and Rb = COOEt
R
Ra = Et and Rb = COOEt
Rd = H, Me, Ac, Ts
Ra
Rb
Ra
Ra = Rb = H
Ra = H, Et, Rb = H, COOEt, Br
Rc = Ts, Boc
R = H, OMe
References:
Professor Jonathan S. Lindsey Professor Deevi Basavaiah
Glaxo Distinguished University Professor School of Chemistry
Department of Chemistry University of Hyderabad
NC State University Hyderabad-5000046, AP, India
Raleigh, NC 27695-8204 Tel: +91-40-23010977 (R)
Tel: (919)-515-2940 +91-40-23134812 (O)
Fax: (919)-513-2830 Fax: +91-40-23012460
E-mail: jlindsey@ncsu.edu E-mail:dbsc@uohyd.ernet.in
6