This document provides information on the anatomy, variations, and imaging of the kidneys, ureters, and bladder. It describes the typical location and shape of the kidneys and discusses common anatomical variations. Details are given on renal vasculature and collecting system anatomy. Common congenital anomalies of the kidneys are described. The document also provides imaging protocols for intravenous urography and discusses the goals and findings at different phases of the exam. Contraindications to iodinated contrast are outlined.
Radiological anatomy of pancreas and spleenPankaj Kaira
This document provides an overview of the radiological anatomy of the pancreas and spleen. It describes the locations and structures of the pancreas including the head, neck, body and tail. It also describes the pancreatic duct and its branches. For the spleen it describes the location, size, weight and blood supply. It then discusses several anatomical variations and congenital anomalies that can occur for both the pancreas and spleen such as pancreas divisum, annular pancreas, ectopic pancreas, polysplenia, splenosis and wandering spleen.
The document discusses the development of the urinary system from the intermediate mesoderm. It describes the development of the pronephros, mesonephros, and metanephros in craniocaudal direction. It discusses the fate of each structure and their roles in male and female development. Congenital anomalies such as horseshoe kidney, renal ectopia, duplication abnormalities, and ureterocele are described. Imaging findings of these conditions on ultrasound, intravenous urography, and CT are provided.
This document provides an overview of the embryological development and radiological anatomy of the kidney, ureter, and bladder. It describes the development of the pronephros, mesonephros and metanephros from the intermediate mesoderm. Key details about the anatomy and variations of the kidney calyces, pelvis, cortex and medulla are discussed. The course and appearance of the ureter on intravenous pyelogram is also summarized.
1. Anorectal malformations are congenital anomalies of the anus and rectum that occur in approximately 1 in 5,000 live births.
2. The document describes various classifications of anorectal malformations and discusses the embryological development of the condition.
3. Key surgical procedures for repair of anorectal malformations are described, including colostomy, posterior sagittal anorectoplasty, and pull-through operations. The repair approaches are discussed depending on the specific type of malformation.
The document describes the sonographic appearance of the fetal kidneys, bladder, and urinary tract. It discusses how the kidneys appear hyper-echoic and oval shaped in the first trimester, becoming less echogenic over time with corticomedullary differentiation appearing at 14-15 weeks. The bladder is first seen at 9 weeks gestation and empties every 25-30 minutes in the second and third trimester. Various urinary tract abnormalities are described such as renal agenesis, ectopic or fused kidneys, renal cystic diseases, hydronephrosis, and lower urinary tract obstruction. Causes, appearances, and characteristics of different abnormalities are provided.
The document summarizes kidney development from the pronephros, mesonephros, and metanephros stages. It describes how the ureteric bud and metanephric blastema form the metanephros which becomes the definitive kidney. Several congenital renal anomalies are discussed, including pelvic kidney, horseshoe kidney, crossed ectopia, and multicystic dysplastic kidney. Autosomal recessive polycystic kidney disease is noted to affect the kidneys, lungs, and liver due to mutations in the PKHD1 gene.
This document provides an overview of common congenital anomalies of the genitourinary system. It discusses abnormalities of the kidneys, ureters, bladder, urethra, and genitals. For each anomaly, it describes the presentation, evaluation, and typical treatment approaches. Common anomalies covered include horseshoe kidney, pelviureteric junction obstruction, vesicoureteric reflux, duplication of the urinary system, ectopic ureter, uretrocele, undescended testis, hypospadias, epispadias, bladder extrophy, and posterior urethral valves.
The document discusses various congenital anomalies of the kidneys including anomalies of number (unilateral and bilateral renal agenesis), ascent (renal ectopia), form and fusion (horseshoe kidney), rotation, collecting system (duplex system, calyceal diverticulum), and vasculature. Specific conditions discussed in more detail include Potter syndrome resulting from bilateral renal agenesis, horseshoe kidney, multicystic dysplastic kidney, autosomal recessive and dominant polycystic kidney disease, and medullary sponge kidney. Imaging features of many of these anomalies are also presented.
Radiological anatomy of pancreas and spleenPankaj Kaira
This document provides an overview of the radiological anatomy of the pancreas and spleen. It describes the locations and structures of the pancreas including the head, neck, body and tail. It also describes the pancreatic duct and its branches. For the spleen it describes the location, size, weight and blood supply. It then discusses several anatomical variations and congenital anomalies that can occur for both the pancreas and spleen such as pancreas divisum, annular pancreas, ectopic pancreas, polysplenia, splenosis and wandering spleen.
The document discusses the development of the urinary system from the intermediate mesoderm. It describes the development of the pronephros, mesonephros, and metanephros in craniocaudal direction. It discusses the fate of each structure and their roles in male and female development. Congenital anomalies such as horseshoe kidney, renal ectopia, duplication abnormalities, and ureterocele are described. Imaging findings of these conditions on ultrasound, intravenous urography, and CT are provided.
This document provides an overview of the embryological development and radiological anatomy of the kidney, ureter, and bladder. It describes the development of the pronephros, mesonephros and metanephros from the intermediate mesoderm. Key details about the anatomy and variations of the kidney calyces, pelvis, cortex and medulla are discussed. The course and appearance of the ureter on intravenous pyelogram is also summarized.
1. Anorectal malformations are congenital anomalies of the anus and rectum that occur in approximately 1 in 5,000 live births.
2. The document describes various classifications of anorectal malformations and discusses the embryological development of the condition.
3. Key surgical procedures for repair of anorectal malformations are described, including colostomy, posterior sagittal anorectoplasty, and pull-through operations. The repair approaches are discussed depending on the specific type of malformation.
The document describes the sonographic appearance of the fetal kidneys, bladder, and urinary tract. It discusses how the kidneys appear hyper-echoic and oval shaped in the first trimester, becoming less echogenic over time with corticomedullary differentiation appearing at 14-15 weeks. The bladder is first seen at 9 weeks gestation and empties every 25-30 minutes in the second and third trimester. Various urinary tract abnormalities are described such as renal agenesis, ectopic or fused kidneys, renal cystic diseases, hydronephrosis, and lower urinary tract obstruction. Causes, appearances, and characteristics of different abnormalities are provided.
The document summarizes kidney development from the pronephros, mesonephros, and metanephros stages. It describes how the ureteric bud and metanephric blastema form the metanephros which becomes the definitive kidney. Several congenital renal anomalies are discussed, including pelvic kidney, horseshoe kidney, crossed ectopia, and multicystic dysplastic kidney. Autosomal recessive polycystic kidney disease is noted to affect the kidneys, lungs, and liver due to mutations in the PKHD1 gene.
This document provides an overview of common congenital anomalies of the genitourinary system. It discusses abnormalities of the kidneys, ureters, bladder, urethra, and genitals. For each anomaly, it describes the presentation, evaluation, and typical treatment approaches. Common anomalies covered include horseshoe kidney, pelviureteric junction obstruction, vesicoureteric reflux, duplication of the urinary system, ectopic ureter, uretrocele, undescended testis, hypospadias, epispadias, bladder extrophy, and posterior urethral valves.
The document discusses various congenital anomalies of the kidneys including anomalies of number (unilateral and bilateral renal agenesis), ascent (renal ectopia), form and fusion (horseshoe kidney), rotation, collecting system (duplex system, calyceal diverticulum), and vasculature. Specific conditions discussed in more detail include Potter syndrome resulting from bilateral renal agenesis, horseshoe kidney, multicystic dysplastic kidney, autosomal recessive and dominant polycystic kidney disease, and medullary sponge kidney. Imaging features of many of these anomalies are also presented.
This document discusses the exstrophy-epispadias complex (EEC), which includes three main presentations: epispadias, classic bladder exstrophy (CBE), and cloacal exstrophy (CE). It describes the presentations, epidemiology, risk factors, etiology, functional anatomy, associated anomalies, diagnosis, and management of EEC. The main goals of EEC reconstruction are to close the bladder and abdominal wall in CBE and CE, while addressing associated urogenital, musculoskeletal, gastrointestinal, and neurologic anomalies.
The document discusses the embryology, evolution, development and clinical presentations of the renal duplex system. Some key points:
- The duplex system occurs when the kidney is divided into two separate collecting systems due to early splitting of the ureteric bud. This can result in complete or partial duplication of the ureters and pelvicalyceal systems.
- Complete duplication is rare and can cause issues like vesicoureteric reflux, ureterocele formation, and ectopic ureter insertion. Incomplete duplication is more common but usually asymptomatic.
- Diagnosis involves ultrasound, MCUG, MAG3 and DMSA scans to assess kidney function and rule out issues
it is uploaded to create awareness about congenital abnormality of urinary system. it also help nursing & paramedics educators to teach their students about it.
A MCU was performed on a 2-year-old child with a history of recurrent UTIs. The study identified vesicoureteric reflux (VUR), where urine flows back from the bladder into the ureters and kidneys. VUR was graded as [grade], indicating [description of grade]. In another case, a MCU was performed on a 2-year-old boy with difficulty urinating. This showed a fusiform dilatation and elongation of the proximal posterior urethra persisting during voiding, as well as a transverse filling defect, indicating the presence of posterior urethral valves. Posterior urethral valves are congenital folds of tissue in the posterior
The document summarizes the technique for performing an ultrasound examination of the kidneys. It outlines the proper probe selection, patient positioning, and scanning approaches. It describes how to obtain longitudinal and transverse views of both kidneys and minimum images that should be included. Normal kidney anatomy is defined including dimensions, cortex thickness and echogenicity compared to liver. Causes of non-pathological renal pelvis dilation are listed.
The document discusses the embryological development, classification, clinical features, investigations, and management of benign anorectal diseases such as imperforate anus, anorectal malformations, and rectal prolapse. It describes the normal development of the anorectum and various congenital anomalies that can occur. Evaluation methods including invertograms and defecography are outlined, as well as surgical techniques for repair of anomalies like posterior sagittal anorectoplasty.
This document discusses rectal prolapse, including its anatomy, causes, types, clinical features, investigations, and management. It begins with the anatomy of the rectum and its blood supply. It then describes the causes of rectal prolapse as being related to decreased pelvic floor muscle tone. It outlines the types of rectal prolapse as partial, complete, or internal. Management involves dietary changes and injections for partial prolapse or surgery like rectopexy or STARR procedure for complete prolapse.
The spleen is an organ located in the upper left abdomen. It filters blood and fights infections. A splenectomy is the surgical removal of the spleen. It is usually performed laparoscopically to avoid complications of open surgery. During the procedure, the surgeon uses cameras and surgical tools inserted through small incisions to carefully dissect and divide attachments of the spleen. This allows the spleen to be removed while preserving surrounding structures like the pancreas and stomach. A splenectomy may be recommended for conditions like immune thrombocytopenia or certain blood disorders.
Radiology of urogenital systsm slide shareREKHAKHARE
This document provides an overview of the urinary system and genital structures from an imaging perspective. It discusses kidney, ureter, bladder, prostate, testes, and scrotum anatomy. It also reviews embryological development of the renal system and various congenital anomalies that can occur. Imaging modalities for evaluating the urinary system are outlined, along with approaches to specific conditions like renal masses and parenchymal lesions. Key topics covered include polycystic kidney disease, renal cell carcinoma, horseshoe kidney, and other structural abnormalities.
The document provides an overview of the anatomy and imaging techniques of the urinary tract. It describes the pelvicalyceal system including the minor and major calyces that drain into the renal pelvis. It notes the locations of the renal hilum and discusses the ureters, bladder, and urethra. Common congenital anomalies are described such as duplex collecting systems, ureteropelvic junction obstruction, megacalyces, and calyceal diverticula. Imaging modalities for evaluating the urinary tract include KUB, IVP, ultrasound, MRI, and urethrograms. Characteristic signs of conditions like papillary necrosis are also outlined.
Gall bladder & biliary tract anomalies and variantsSanal Kumar
This document describes the normal anatomy of the gallbladder and biliary tract, as well as common anatomical variations and anomalies. It discusses the normal divisions and structures of the gallbladder and cystic duct. It then covers several anomalies including agenesis of the gallbladder, gallbladder duplication, wandering gallbladder, gallbladder torsion, and variations in gallbladder shape. The document also discusses ectopic locations of the gallbladder and variations in cystic duct insertion and bile duct anatomy.
This document discusses various fetal abnormalities that can be detected on prenatal ultrasound. It describes ectopic and pelvic kidneys, prune belly syndrome, megacystis microcolon intestinal hypoperistalsis syndrome, adrenal glands, neuroblastoma, bladder abnormalities like extrophy and non-visualization, genital abnormalities like hypospadias, congenital adrenal hyperplasia, ovarian cysts, and hydrocolpos/hydrometrocolpos. Differential diagnoses and key sonographic findings for each condition are provided.
Congenital Development of Urinary System.pptchallenger0326
1. Congenital anomalies of the kidney and urinary tract are abnormalities that develop before birth and can affect the structure and function of the kidneys and urinary system.
2. Some of the main anomalies discussed include renal agenesis (absent kidney), hypoplasia (small kidney), dysplasia (abnormal structure of kidney), and abnormalities in kidney position. Other anomalies affect the collecting system like duplex kidneys, hydronephrosis, and posterior urethral valves.
3. These anomalies can have various clinical presentations ranging from asymptomatic to end stage renal disease. They often require long term follow up and management to monitor renal and bladder function and address any complications. Bilateral involvement or
This document provides an overview of kidney and ureter embryology and surgical anatomy. It discusses the development of the pronephros, mesonephros and metanephros. The mesonephric duct gives rise to the ureteric bud which develops into the collecting system. Congenital anomalies including renal agenesis, horseshoe kidney and duplex collecting system are described. The surgical anatomy of the kidneys and their blood supply from the renal arteries is summarized. The relationships of the kidneys to surrounding structures and fascial layers including Gerota's fascia are also outlined.
The document discusses various congenital anomalies of the pancreas including annular pancreas, pancreas divisum, ectopic pancreatic tissue, horseshoe pancreas, and variations in pancreatic ductal anatomy. It describes the embryological development of the pancreas and defines important anatomical structures such as the pancreatic ducts. Imaging features of different pancreatic anomalies on modalities like CT, MRI, ERCP, and ultrasound are provided.
Development and congenital anomalies of urogenital systemJayeta Choudhury
The document discusses development and congenital anomalies of the urogenital system. It begins by explaining how the urinary and genital systems develop from a common ridge in the embryo and open into a common channel, the cloaca. It then describes the development of the three kidney systems - pronephros, mesonephros, and metanephros. Next, it discusses anomalies that can occur, including anomalies of form (agenesis, hypoplasia, supernumerary kidneys), position (malrotation, ectopic kidneys), and fusion (horseshoe kidney, crossed fused renal ectopia, cake kidney). It concludes by covering congenital cystic renal diseases and the approach to differentiating them using ultrasound findings
Embryonic development of the urogenital systemAsheer Khan
The urogenital system develops from the intermediate mesenchyme. The urinary system develops from the nephrogenic cord, while the genital system develops from the gonadal ridge. Three sets of kidneys develop in embryos - the pronephroi, mesonephroi, and metanephroi. The metanephroi form the permanent kidneys. The kidneys and ureters develop from the ureteric bud and metanephrogenic blastema. Congenital anomalies that can occur include renal agenesis, malrotated kidneys, ectopic kidneys, horseshoe kidneys, and duplications of the urinary tract. The urinary bladder develops mainly from the vesical
The document summarizes the embryology and molecular mechanisms of kidney development. It discusses that the kidney develops from the intermediate mesoderm and progresses through pronephros, mesonephros, and metanephros stages. The ureteric bud invades the metanephric mesenchyme and branches to form the collecting system. GDNF signaling from the metanephric mesenchyme induces branching of the ureteric bud. Defects in genes involved in these signaling pathways, such as PAX2, EYA1, and WT1, can lead to kidney abnormalities. The molecular mechanisms demonstrate the importance of epithelial-mesenchymal interactions in nephrogenesis.
The document provides information on the anatomy, normal variants, and ultrasound imaging of the kidney, ureter, urinary bladder, and prostate. It describes the location, structure, blood supply, and size of the kidney. It discusses variants such as horseshoe kidney and renal cysts/masses. Hydronephrosis and its grading are also covered. The anatomy and constriction points of the ureter are summarized. Indications for ultrasound of the bladder include hematuria and infection. Normal and abnormal bladder findings like thickening, tumors, and calculi are outlined. Lastly, the zonal anatomy, blood supply, and common pathology of the prostate are briefly described to introduce transrectal ultrasound examination.
This document provides a framework for realigning curriculum content to facilitate learning during the COVID-19 pandemic. It aims to ensure minimum learning outcomes for students while continuing their education despite school closures. The framework suggests prioritizing, grouping, and reducing curriculum content to focus on essential topics that can be taught through alternative means like online learning, radio broadcasts, or television. Teachers are advised to assess learning and provide support through local experts, parents, and older students. The framework is intended as a guide that can be adapted locally while ensuring students achieve minimum learning outcomes.
This letter commits to assisting Takshashila College in obtaining affiliation from Far Western University for its Bachelor of Business Administration and Bachelor of Computer Science and Information Technology programs. The letter writer pledges to provide their academic credentials to the relevant organizations and help refer the college's application.
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This document discusses the exstrophy-epispadias complex (EEC), which includes three main presentations: epispadias, classic bladder exstrophy (CBE), and cloacal exstrophy (CE). It describes the presentations, epidemiology, risk factors, etiology, functional anatomy, associated anomalies, diagnosis, and management of EEC. The main goals of EEC reconstruction are to close the bladder and abdominal wall in CBE and CE, while addressing associated urogenital, musculoskeletal, gastrointestinal, and neurologic anomalies.
The document discusses the embryology, evolution, development and clinical presentations of the renal duplex system. Some key points:
- The duplex system occurs when the kidney is divided into two separate collecting systems due to early splitting of the ureteric bud. This can result in complete or partial duplication of the ureters and pelvicalyceal systems.
- Complete duplication is rare and can cause issues like vesicoureteric reflux, ureterocele formation, and ectopic ureter insertion. Incomplete duplication is more common but usually asymptomatic.
- Diagnosis involves ultrasound, MCUG, MAG3 and DMSA scans to assess kidney function and rule out issues
it is uploaded to create awareness about congenital abnormality of urinary system. it also help nursing & paramedics educators to teach their students about it.
A MCU was performed on a 2-year-old child with a history of recurrent UTIs. The study identified vesicoureteric reflux (VUR), where urine flows back from the bladder into the ureters and kidneys. VUR was graded as [grade], indicating [description of grade]. In another case, a MCU was performed on a 2-year-old boy with difficulty urinating. This showed a fusiform dilatation and elongation of the proximal posterior urethra persisting during voiding, as well as a transverse filling defect, indicating the presence of posterior urethral valves. Posterior urethral valves are congenital folds of tissue in the posterior
The document summarizes the technique for performing an ultrasound examination of the kidneys. It outlines the proper probe selection, patient positioning, and scanning approaches. It describes how to obtain longitudinal and transverse views of both kidneys and minimum images that should be included. Normal kidney anatomy is defined including dimensions, cortex thickness and echogenicity compared to liver. Causes of non-pathological renal pelvis dilation are listed.
The document discusses the embryological development, classification, clinical features, investigations, and management of benign anorectal diseases such as imperforate anus, anorectal malformations, and rectal prolapse. It describes the normal development of the anorectum and various congenital anomalies that can occur. Evaluation methods including invertograms and defecography are outlined, as well as surgical techniques for repair of anomalies like posterior sagittal anorectoplasty.
This document discusses rectal prolapse, including its anatomy, causes, types, clinical features, investigations, and management. It begins with the anatomy of the rectum and its blood supply. It then describes the causes of rectal prolapse as being related to decreased pelvic floor muscle tone. It outlines the types of rectal prolapse as partial, complete, or internal. Management involves dietary changes and injections for partial prolapse or surgery like rectopexy or STARR procedure for complete prolapse.
The spleen is an organ located in the upper left abdomen. It filters blood and fights infections. A splenectomy is the surgical removal of the spleen. It is usually performed laparoscopically to avoid complications of open surgery. During the procedure, the surgeon uses cameras and surgical tools inserted through small incisions to carefully dissect and divide attachments of the spleen. This allows the spleen to be removed while preserving surrounding structures like the pancreas and stomach. A splenectomy may be recommended for conditions like immune thrombocytopenia or certain blood disorders.
Radiology of urogenital systsm slide shareREKHAKHARE
This document provides an overview of the urinary system and genital structures from an imaging perspective. It discusses kidney, ureter, bladder, prostate, testes, and scrotum anatomy. It also reviews embryological development of the renal system and various congenital anomalies that can occur. Imaging modalities for evaluating the urinary system are outlined, along with approaches to specific conditions like renal masses and parenchymal lesions. Key topics covered include polycystic kidney disease, renal cell carcinoma, horseshoe kidney, and other structural abnormalities.
The document provides an overview of the anatomy and imaging techniques of the urinary tract. It describes the pelvicalyceal system including the minor and major calyces that drain into the renal pelvis. It notes the locations of the renal hilum and discusses the ureters, bladder, and urethra. Common congenital anomalies are described such as duplex collecting systems, ureteropelvic junction obstruction, megacalyces, and calyceal diverticula. Imaging modalities for evaluating the urinary tract include KUB, IVP, ultrasound, MRI, and urethrograms. Characteristic signs of conditions like papillary necrosis are also outlined.
Gall bladder & biliary tract anomalies and variantsSanal Kumar
This document describes the normal anatomy of the gallbladder and biliary tract, as well as common anatomical variations and anomalies. It discusses the normal divisions and structures of the gallbladder and cystic duct. It then covers several anomalies including agenesis of the gallbladder, gallbladder duplication, wandering gallbladder, gallbladder torsion, and variations in gallbladder shape. The document also discusses ectopic locations of the gallbladder and variations in cystic duct insertion and bile duct anatomy.
This document discusses various fetal abnormalities that can be detected on prenatal ultrasound. It describes ectopic and pelvic kidneys, prune belly syndrome, megacystis microcolon intestinal hypoperistalsis syndrome, adrenal glands, neuroblastoma, bladder abnormalities like extrophy and non-visualization, genital abnormalities like hypospadias, congenital adrenal hyperplasia, ovarian cysts, and hydrocolpos/hydrometrocolpos. Differential diagnoses and key sonographic findings for each condition are provided.
Congenital Development of Urinary System.pptchallenger0326
1. Congenital anomalies of the kidney and urinary tract are abnormalities that develop before birth and can affect the structure and function of the kidneys and urinary system.
2. Some of the main anomalies discussed include renal agenesis (absent kidney), hypoplasia (small kidney), dysplasia (abnormal structure of kidney), and abnormalities in kidney position. Other anomalies affect the collecting system like duplex kidneys, hydronephrosis, and posterior urethral valves.
3. These anomalies can have various clinical presentations ranging from asymptomatic to end stage renal disease. They often require long term follow up and management to monitor renal and bladder function and address any complications. Bilateral involvement or
This document provides an overview of kidney and ureter embryology and surgical anatomy. It discusses the development of the pronephros, mesonephros and metanephros. The mesonephric duct gives rise to the ureteric bud which develops into the collecting system. Congenital anomalies including renal agenesis, horseshoe kidney and duplex collecting system are described. The surgical anatomy of the kidneys and their blood supply from the renal arteries is summarized. The relationships of the kidneys to surrounding structures and fascial layers including Gerota's fascia are also outlined.
The document discusses various congenital anomalies of the pancreas including annular pancreas, pancreas divisum, ectopic pancreatic tissue, horseshoe pancreas, and variations in pancreatic ductal anatomy. It describes the embryological development of the pancreas and defines important anatomical structures such as the pancreatic ducts. Imaging features of different pancreatic anomalies on modalities like CT, MRI, ERCP, and ultrasound are provided.
Development and congenital anomalies of urogenital systemJayeta Choudhury
The document discusses development and congenital anomalies of the urogenital system. It begins by explaining how the urinary and genital systems develop from a common ridge in the embryo and open into a common channel, the cloaca. It then describes the development of the three kidney systems - pronephros, mesonephros, and metanephros. Next, it discusses anomalies that can occur, including anomalies of form (agenesis, hypoplasia, supernumerary kidneys), position (malrotation, ectopic kidneys), and fusion (horseshoe kidney, crossed fused renal ectopia, cake kidney). It concludes by covering congenital cystic renal diseases and the approach to differentiating them using ultrasound findings
Embryonic development of the urogenital systemAsheer Khan
The urogenital system develops from the intermediate mesenchyme. The urinary system develops from the nephrogenic cord, while the genital system develops from the gonadal ridge. Three sets of kidneys develop in embryos - the pronephroi, mesonephroi, and metanephroi. The metanephroi form the permanent kidneys. The kidneys and ureters develop from the ureteric bud and metanephrogenic blastema. Congenital anomalies that can occur include renal agenesis, malrotated kidneys, ectopic kidneys, horseshoe kidneys, and duplications of the urinary tract. The urinary bladder develops mainly from the vesical
The document summarizes the embryology and molecular mechanisms of kidney development. It discusses that the kidney develops from the intermediate mesoderm and progresses through pronephros, mesonephros, and metanephros stages. The ureteric bud invades the metanephric mesenchyme and branches to form the collecting system. GDNF signaling from the metanephric mesenchyme induces branching of the ureteric bud. Defects in genes involved in these signaling pathways, such as PAX2, EYA1, and WT1, can lead to kidney abnormalities. The molecular mechanisms demonstrate the importance of epithelial-mesenchymal interactions in nephrogenesis.
The document provides information on the anatomy, normal variants, and ultrasound imaging of the kidney, ureter, urinary bladder, and prostate. It describes the location, structure, blood supply, and size of the kidney. It discusses variants such as horseshoe kidney and renal cysts/masses. Hydronephrosis and its grading are also covered. The anatomy and constriction points of the ureter are summarized. Indications for ultrasound of the bladder include hematuria and infection. Normal and abnormal bladder findings like thickening, tumors, and calculi are outlined. Lastly, the zonal anatomy, blood supply, and common pathology of the prostate are briefly described to introduce transrectal ultrasound examination.
This document provides a framework for realigning curriculum content to facilitate learning during the COVID-19 pandemic. It aims to ensure minimum learning outcomes for students while continuing their education despite school closures. The framework suggests prioritizing, grouping, and reducing curriculum content to focus on essential topics that can be taught through alternative means like online learning, radio broadcasts, or television. Teachers are advised to assess learning and provide support through local experts, parents, and older students. The framework is intended as a guide that can be adapted locally while ensuring students achieve minimum learning outcomes.
This letter commits to assisting Takshashila College in obtaining affiliation from Far Western University for its Bachelor of Business Administration and Bachelor of Computer Science and Information Technology programs. The letter writer pledges to provide their academic credentials to the relevant organizations and help refer the college's application.
UTTAM PANDEY, ESQ.
Uttam Pandey, Esq. is serving clients through Chhetry & Associates, as an Associate from March 2021. He is licensed to practice law in New York on April 2019. Prior to this, Attorney Pandey practiced law in Bhurtel Law Firm PLLC, Jackson Heights, New York since his entrance into the New York State Bar. He is a member of New York State Bar Association.
Attorney Pandey completed LL.M. from St. John’s University School of Law, Queens, New York. He also completed LL.M. from Kathmandu School of Law, Purbanchal University, Nepal in which he bagged Gold Medal by being a top scorer in Examinations. He has also completed Masters in Public Administration (MPA) from Tribhuvan University, Nepal. His basic Law Graduation was from Nepal Law Campus, Tribhuvan University after completion of the Degree of Bachelor of Laws (B.L.)
Mr. Pandey was also licensed as an Advocate from Supreme Court of Nepal. He then competed in Police Service Examinations for the position of Police Inspector, succeeded and was commissioned as a Senior Police Officer in Nepal Police where he served until June 2013, for 18+ years. Mr. Pandey has also served UN Peace Mission for more than two years in Timor-Leste as an UNPOL Officer. During his tenure, having legal background, he mostly worked in legal and investigations responsibilities. After coming into USA, he successfully pursued the legal education, passed NY Bar Exam and is licensed as an Attorney-at-Law.
AFFIDAVIT ON EXTRAORDINARY BY A PETITIONER-1.docxNeerajOjha17
UTTAM PANDEY, ESQ.
Uttam Pandey, Esq. is serving clients through Chhetry & Associates, as an Associate from March 2021. He is licensed to practice law in New York on April 2019. Prior to this, Attorney Pandey practiced law in Bhurtel Law Firm PLLC, Jackson Heights, New York since his entrance into the New York State Bar. He is a member of New York State Bar Association.
Attorney Pandey completed LL.M. from St. John’s University School of Law, Queens, New York. He also completed LL.M. from Kathmandu School of Law, Purbanchal University, Nepal in which he bagged Gold Medal by being a top scorer in Examinations. He has also completed Masters in Public Administration (MPA) from Tribhuvan University, Nepal. His basic Law Graduation was from Nepal Law Campus, Tribhuvan University after completion of the Degree of Bachelor of Laws (B.L.)
Mr. Pandey was also licensed as an Advocate from Supreme Court of Nepal. He then competed in Police Service Examinations for the position of Police Inspector, succeeded and was commissioned as a Senior Police Officer in Nepal Police where he served until June 2013, for 18+ years. Mr. Pandey has also served UN Peace Mission for more than two years in Timor-Leste as an UNPOL Officer. During his tenure, having legal background, he mostly worked in legal and investigations responsibilities. After coming into USA, he successfully pursued the legal education, passed NY Bar Exam and is licensed as an Attorney-at-Law.
Mampi Ghosh is submitting an affidavit in support of an I-140 immigrant petition for an alien worker under the EB-1 extraordinary ability category as a broadcast journalist/media personality. The affidavit outlines Ghosh's extensive experience and accomplishments as a radio and television presenter in Nepal over the past 8 years, including hosting popular shows and receiving several national awards. It also details Ghosh's membership and work with reputable organizations like the United Nations Population Fund.
Khagendra Gharti-Chhetry, Esq., the founding partner of Chhetry & Associates P.C. has been practicing law since 1987. He has extensive experience in immigration law matters, including litigation, divorce, business law, real estate and bankruptcy. For over twenty five years, Mr. Chhetry has been providing legal services to individuals, small and medium size businesses and corporations. His adept and successful handling of cases has earned him a good reputation among both his clients and colleagues. Mr. Chhetry is admitted to practice before the courts in the State of New York, United State District Courts for Southern and Eastern Districts, and before the Supreme Court of the United States. He is a member of several prestigious legal organizations, including American Bar Association, New York Bar Association, Nepal Bar Association, Indo-American Lawyers Association. He is also the President of Columbia University Alumni Association’s Nepal Chapter. Mr. Chhetry is the author of articles “Right of Self-Defense under the United Nations Charter” and “Juvenile Court—A Necessity in Nepal.” Mr. Chhetry received his J.D. from Fordham University, School of Law and his LL.M from Columbia University, School of Law, in New York City.
Avima Upreti, Esq., is an attorney at Chhetry and Associates. She has in-depth knowledge and experience in Immigration law, including Asylum, Cancellation of Removal, EB1/EB2, National Interest Waiver, H1B, PERM/Labor certification, F1 visa, VAWA, Adjustment of status, Consular process, Family law and guardianship proceedings.
She started her career as a foreign associate, handling immigration cases. She handles cases efficiently, hears her clients thoroughly, works with them to provide accurate legal solutions, and is determined to provide the best service. She has been working with the firm since 2014.
Ms. Upreti also has extensive experience working as a human right activist and feminist in Nepal and the United States. She worked as a news anchor and legal reporter for the National Television of Nepal. She is currently serving as the President of the Nepali Women’s Global Network (NWGN) (2018-2022), where she is focused on raising issues of Diversity, Equity and Inclusiveness. She also raises issue against violence and gender-based discrimination. She is a passionate public speaker.
Ms. Upreti is licensed to practice law before the New York State courts. She is also admitted to practice law as an advocate in Nepal. She received her LLM (recipient of cum laude) from Fordham Law School, New York, in international law and justice 2016-2017. She also has an LLM from Kathmandu School of law, Nepal, specializing in Human rights and Gender Justice in 2011-2013. Ms. Upreti completed her law degree from Purbanchal University Kathmandu School of law in Nepal in 2011 on a full merit-based scholarship, receiving an award from the Nepal Bar council for getting the Second highest score all over Nepal on the Advocate license exam in 2012. She can be reached at au@chhetrylaw.com
UTTAM PANDEY, ESQ.
Uttam Pandey, Esq. is serving clients through Chhetry & Associates, as an Associate from March 2021. He is licensed to practice law in New York on April 2019. Prior to this, Attorney Pandey practiced law in Bhurtel Law Firm PLLC, Jackson Heights, New York since his entrance into the New York State Bar. He is a member of New York State Bar Association.
Attorney Pandey completed LL.M. from St. John’s University School of Law, Queens, New York. He also completed LL.M. from Kathmandu School of Law, Purbanchal University, Nepal in which he bagged Gold Medal by being a top scorer in Examinations. He has also completed Masters in Public Administration (MPA) from Tribhuvan University, Nepal. His basic Law Graduation was from Nepal Law Campus, Tribhuvan University after completion of the Degree of Bachelor of Laws (B.L.)
Mr. Pandey was also licensed as an Advocate from Supreme Court of Nepal. He then competed in Police Service Examinations for the position of Police Inspector, succeeded and was commissioned as a Senior Police Officer in Nepal Police where he served until June 2013, for 18+ years. Mr. Pandey has also served UN Peace Mission for more than two years in Timor-Leste as an UNPOL Officer. During his tenure, having legal background, he mostly worked in legal and investigations responsibilities. After coming into USA, he successfully pursued the legal education, passed NY Bar Exam and is licensed as an Attorney-at-Law.
UTTAM PANDEY, ESQ.
Uttam Pandey, Esq. is serving clients through Chhetry & Associates, as an Associate from March 2021. He is licensed to practice law in New York on April 2019. Prior to this, Attorney Pandey practiced law in Bhurtel Law Firm PLLC, Jackson Heights, New York since his entrance into the New York State Bar. He is a member of New York State Bar Association.
Attorney Pandey completed LL.M. from St. John’s University School of Law, Queens, New York. He also completed LL.M. from Kathmandu School of Law, Purbanchal University, Nepal in which he bagged Gold Medal by being a top scorer in Examinations. He has also completed Masters in Public Administration (MPA) from Tribhuvan University, Nepal. His basic Law Graduation was from Nepal Law Campus, Tribhuvan University after completion of the Degree of Bachelor of Laws (B.L.)
Mr. Pandey was also licensed as an Advocate from Supreme Court of Nepal. He then competed in Police Service Examinations for the position of Police Inspector, succeeded and was commissioned as a Senior Police Officer in Nepal Police where he served until June 2013, for 18+ years. Mr. Pandey has also served UN Peace Mission for more than two years in Timor-Leste as an UNPOL Officer. During his tenure, having legal background, he mostly worked in legal and investigations responsibilities. After coming into USA, he successfully pursued the legal education, passed NY Bar Exam and is licensed as an Attorney-at-Law.
UTTAM PANDEY, ESQ.
Uttam Pandey, Esq. is serving clients through Chhetry & Associates, as an Associate from March 2021. He is licensed to practice law in New York on April 2019. Prior to this, Attorney Pandey practiced law in Bhurtel Law Firm PLLC, Jackson Heights, New York since his entrance into the New York State Bar. He is a member of New York State Bar Association.
Attorney Pandey completed LL.M. from St. John’s University School of Law, Queens, New York. He also completed LL.M. from Kathmandu School of Law, Purbanchal University, Nepal in which he bagged Gold Medal by being a top scorer in Examinations. He has also completed Masters in Public Administration (MPA) from Tribhuvan University, Nepal. His basic Law Graduation was from Nepal Law Campus, Tribhuvan University after completion of the Degree of Bachelor of Laws (B.L.)
Mr. Pandey was also licensed as an Advocate from Supreme Court of Nepal. He then competed in Police Service Examinations for the position of Police Inspector, succeeded and was commissioned as a Senior Police Officer in Nepal Police where he served until June 2013, for 18+ years. Mr. Pandey has also served UN Peace Mission for more than two years in Timor-Leste as an UNPOL Officer. During his tenure, having legal background, he mostly worked in legal and investigations responsibilities. After coming into USA, he successfully pursued the legal education, passed NY Bar Exam and is licensed as an Attorney-at-Law.
This document is a letter of support submitted with an I-140 visa petition for Mampi Ghosh, a broadcast journalist from Nepal. It details Ghosh's extraordinary ability and sustained acclaim in the field through her work hosting over 200 television shows and radio programs in Nepal over 8 years. It provides evidence that Ghosh meets 3 of the 10 criteria for extraordinary ability by documenting several lesser nationally recognized prizes and awards she has received for her work and contributions to Nepali media, including Awards of Excellence in 2008 and 2009.
Mampi Ghosh is submitting an affidavit in support of an I-140 immigrant visa petition based on extraordinary ability as a broadcast journalist and media personality in Nepal. Over the past 8 years, Ghosh has hosted over 200 television shows and stage programs and worked as a radio host for several popular stations in Nepal. Ghosh has received numerous national awards and recognition for contributions to media and was selected to represent Nepal at a UN Commission on the Status of Women.
On October 7, 2011, Upendra Bhatta of The Bhatta Law Firm served documents in support of respondent Makendra Bahadur Singh's asylum application to the Department of Homeland Security's Immigration and Customs Enforcement office located at 26 Federal Plaza in New York, NY. The documents included a police report from May 3, 2011 regarding Singh. Bhatta certified delivering the documents in person on that date while representing Singh in removal proceedings before the New York Immigration Court.
1. The patient, a YEARS/MALE, was admitted to the hospital with fever, chills, headache, myalgia, nose bleed, epigastric pain, vomiting, diarrhea, shortness of breath, and altered consciousness for 5 days.
2. Examination revealed bilateral basal crepitations in the lungs, soft abdomen, and the patient was ill-looking but oriented.
3. Investigations showed fatty liver changes and bilateral minimal pleural effusion on ultrasound. The patient was diagnosed with dengue fever and managed supportively.
4. The patient's condition improved and they were discharged on pantoprazole with advice to follow-up in the medicine OPD within a week
Sailesh Maharjan is a natural product chemist seeking a role in pharmaceutical research and development. He has a Master's degree in Pharmacognosy from Yeungnam University in South Korea and over 5 years of experience in quality control and analysis. His expertise includes isolation, purification, and structural elucidation of compounds using chromatography and spectroscopy. He has published research on natural products and contributed to workshops on NMR and HPLC techniques.
This document contains Sristi Sah's resume. It includes her contact information, career objective, educational qualifications, skills, personal traits, achievements, hobbies, interests, personal details, declaration, and references. Sristi holds a Bachelor's degree in Pharmacy from Central Institution of Science & Technology, Kathmandu, Nepal. She has good communication, computer, presentation, technical, research, leadership, time management, and problem solving skills.
1-A-Define the health system and describe the functions and elements of healt...NeerajOjha17
The document defines a health system as the organization of people, institutions, and resources that deliver health care services to meet the needs of target populations. It describes key elements of health systems including primary health care, public health measures, various providers, and the goals of promoting health, being responsive to populations, and fair financing. The health system of Nepal is composed of public health sectors, private sectors, indigenous medical systems, voluntary health agencies, and national health programs.
This document discusses different models of healthcare systems around the world. It describes four main models: the Bismarck model used in Germany and other countries, where private insurance plans are regulated by the government; the Beveridge model used in the UK with government-provided and tax-funded healthcare; the National Health Insurance model used in Canada with a universal government-run insurance program; and the out-of-pocket model used in many developing countries where most cannot afford medical care. The document then examines the healthcare systems of several countries in more depth and discusses challenges facing Nepal's system.
This document summarizes the historical eras of health systems development (HSD) in Nepal. It is divided into 3 sections: ancient, medieval, and modern eras. During the ancient era, some early health practices are mentioned from historical texts. In the medieval era, King Pratap Malla established an Ayurvedic dispensary. Christian missionaries introduced modern medicine in the 1600s but were later expelled. The modern era saw the establishment of hospitals by British residents and throughout the Rana period. Many hospitals and health programs were developed in the post-democracy period from the 1950s onward.
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Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
Osteoporosis - Definition , Evaluation and Management .pdfJim Jacob Roy
Osteoporosis is an increasing cause of morbidity among the elderly.
In this document , a brief outline of osteoporosis is given , including the risk factors of osteoporosis fractures , the indications for testing bone mineral density and the management of osteoporosis
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Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
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Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
2. Usual location- Upper border of 12th thoracic
vertebra and lower border of L3
In an upright position, kidneys descend by 2
or 3 cm in quiet respiration.
Right kidney is slightly lower than left .
Long axis is directed downwards and
laterally – upper pole nearer the median
plane
3. Bean shaped.
Two poles-
Upper- broad due to presence of adrenal
glands
Lower-pointed
Two borders
Lateral-convex
Medial-concave with hilum in middle
Two surfaces-
Anterior- irregular
Posterior- flat
11. Normal size- 9-14 cm
Right kidney is shorter than left by not more
than 1.5cm
As a rule, Kidney length should not be less
than three vertebral body lengths, and no
more than four vertebral body lengths .
12.
13.
14. The adult kidney may retain some degree of
fetal lobulation. This may involve the entire
kidney or just the middle and lower thirds. It is
frequently bilateral. Fetal lobulation is
distinguished from pathological scarring by
the position of the surface notches: in fetal
lobulation surface notches are between the
calyces, whereas scarring occurs directly over
the calyces.
15.
16. Local bulge or convexity may be seen along
the lateral aspect of left kidney- called
Dromedary hump.
This may be either due to impression of the
spleen or fetal lobulations or both.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30. If left renal vein passes posterior to abdominal aorta it is
termed as retroaortic left renal vein.
It has been suggested the variant can sometimes cause
symptoms such as hematuria and abdominal/flank pain.
31.
32.
33.
34. • The commonest anomaly of development is
duplication of the collecting system, which occurs
in 4% of individuals
It is characterized by an incomplete fusion of
upper and lower pole moieties resulting in a
variety of complete or incomplete duplications of
the collecting system
While considered an anatomical variant, duplex
collecting systems may be complicated by
vesicoureteric reflux, obstruction or ureterocele.
35. Duplex collecting system or duplex kidney
anomalies can be classified into the following
categories depending on the level or lack of
fusion 9-10:
duplex kidney: two separate pelvicalyceal
systems draining a single renal parenchyma
duplex collecting system: a duplex kidney
draining into:
single ureter: i.e. duplex kidney's duplication
pelvicalyceal systems uniting at the pelviureteric
junction (PUJ)
bifid ureter : two ureters that unite before emptying
into the bladder
double ureter (complete duplication)
36.
37. The kidneys may fuse during development
and lead to a horseshoe kidney (1 in 700
births).
In this condition, the kidney is fused across the
midline in its lower pole.
The kidney fail to ascend, as IMA would
impede its upward movement. Such kidneys
are more prone to trauma as they lie across the
vertebral column.
38.
39. One or both kidneys may fail to migrate
cranially, resulting in a persistent pelvic
kidney supplied by a branch of the internal
iliac artery (1 in 1500 births).
40.
41. In crossed fused ectopia, both kidneys are
located on one side of the midline and are
fused with each other.
The lower pole of the normally situated kidney
is fused with the upper pole of the ectopic
kidney.
42.
43. A very rare anomaly called thoracic kidney
(although the diaphragm is usually intact)
occurs when the kidney is found much higher
than its normal position; this may cause an
opacity on a chest radiograph.
44.
45.
46.
47.
48.
49.
50.
51.
52. Ultrasound -The proximal and distal ureters
may be visible on ultrasound when well
distended. Intestinal gas generally obscures the
midportion unless it is abnormally dilated.
53. Duplication of part or all of the ureter occurs in
about 4% of subjects. It is the commonest
significant congenital anomaly of the urinary
tract. Duplication is two to three times commoner
in females
When complete duplication occurs, the ureter
serving the upper renal moiety drains fewer
calyces and is inserted lower into the bladder than
that draining the lower moiety - known as the
Weigert-Meyer law.
Ureterocoele is a dilation of the intramural
portion of the ureter due to narrowing of its
orifice. This is most common in a duplicated
system.
54.
55.
56.
57.
58.
59.
60.
61.
62.
63.
64.
65. Diverticulum is the outward bulge of the inner
epithelial lining of the bladder through a defect
in its muscular layer.
It may be congenital or acquired
66.
67. Bladder trabeculation happens when the walls
of the bladder thicken, making them harder to
contract.
It causes retention of urine as it gets difficult to
empty the bladder.
68.
69. The male urethra runs from the internal
urethral sphincter at the neck of the bladder to
the external urethral orifice at the tip of the
penis.
In radiological terms ,it may be divided into
posterior and anterior parts. The posterior
urethra comprises the prostatic and
membranous urethra and the anterior part
comprises the bulbous and penile urethra.
70. Female urethra is 4 cm long
It extends from the internal urethral sphincter
at the bladder neck through the urogenital
diaphragm to the external urethral meatus
anterior to the vaginal opening. It curves
obliquely downward and anteriorly.
71.
72. A posterior urethral valve (PUV) is an
abnormal congenital obstructing membrane
that is located within the posterior
male urethra; this valve is the most common
cause of bladder outlet obstruction in male
children
73.
74. 3 zones : peripheral, transition and central
TZ: (5%)- Bilobed zome
CZ(<25%)
PZ ( <70%) Envelope the CZ – majority of the
gland at the apex.
75. The seminal vesicles are seen as paired,relatively hypoechoic,
symmetric structures cephalad to the base of the prostate
high signal-intensity fluid on T2WI.
Their size may vary depending on age and postejaculatory
condition
The caudal tip of each seminal vesicle joins the corresponding
deferent duct to form the ejaculatory duct.
76.
77. The prostate appears on CT scans as a
homogeneous well-marginated soft tissue
structure, 2-4 cm in length located just beneath the
symphysis pubis immediately anterior to the
rectum
78. The scrotum covering layers are normally
indistinguishable by sonography and visualized
as single echogenic stripe.
The testes are homogenous and of medium level
reflectivity
At birth the testis measures approximately 1.5cm
in length and 1.0cm in width, and before 12 years
of age the testicular volume is 1-2mLs.
Adult: 3- 5cm in length, 2-4 cm width & 3 cm in
AP.
12.5-19 g in weight
80. • The epididymal head is a pyramid shaped structure lying
superior to the upper pole of the testis. The body courses
along the postero-lateral aspect of the testicle.
• The body and tail are of slightly lower reflectivity when
compared with the testis, whilst the head is of slightly
higher reflectivity or isoechoic .
• The appendix epididymis is not as frequently seen as the
appendix testis .
• The epididymal head measures 10-12mm in diameter &
the body less than 4mm (average 1-2mm) in diameter
83. Detect and localize a ureteric obstruction
(urolithiasis)
Unknown hematuria
Assess for synchronous upper tract disease in
those with bladder transitional cell carcinoma
(TCC)
Check for normal function of kidneys
Check for anatomical variants or congenital anomalies
(e.g. horse-shoe kidney)
Check the course of the ureters
84. Proven or suspected hypersensitivity to iodine.
Heart disease –cardiac failure /arrhythmias
may be precipitated and in these cases lower
risk with LOCM
Dehydration
Renal impairment
Myelomatosis
Sickle cell anemia
Thyrotoxicosis
Pregnancy
Contraindications
92. The exact protocol may vary according to the department
rules and need of the patient.
1. Preliminary/scout Film
Administration of CM
2. Nephrographic film
3. 5 minute film
Abdominal compression
4. 10 minute renal and upper urinary tract film
5. 15 minute release film of ureter and bladder
6. Bladder image
7. Post micturition image
Modifications can be used in any steps if the image is not
satisfactory.
93. Done to check exposure
factors, centering, bowel
preparation and obvious
pathology, particularly
UT calcification.
Technical considerations:
Positioning, Proper collimation,
Proper KVP and amperage/exposure
time
94. Location of calcifications in the abdomen with
respect to the urinary tract should be made prior
to the injection of contrast material, which can
obscure a calcification.
96. AP view of renal areas.
This film is exposed 10-14 seconds after contrast
injection (arm to kidney time)
Aim: to show nephrogram
97.
98. What to see in Nephrographic phase?
• Temporal symmetry of
nephrographic development.
• Entire renal contour- Entire contour
should be assessed , inability to
visualize a portion of contour
requires explanation
• Position and axis
• Size of both kidneys.
99. Normal size: 10-15
cm cephalocaudal,
left is 1.5 cm longer
than right.
Not more than 3
times the sum of the
height of L1 vertebra
and height of L1-L2
intervertebral disc.
100. Right kidney is more than 1.5cm
larger than left kidney
Left kidney is more than 2cm larger
than right kidney
101. AP view of renal areas
Initial assessment o pathology.
103.
Average thickness 3-3.5cm in polar region and
2-2.5cm in interpolar region
Decreased and increased
parenchymal thickness to be assessed
Interpapillary line
104. Abdominal aortic aneurysm
Recent abdominal surgery
If patients abdomen is tender
Acute painful abdomen/ renal colic
Large abdominal mass
Evidence of obstruction in 5 minute film
Suspected urinary tract trauma
Presence of urinary diversion or renal transplant
105.
106. Supine AP film
This film is taken to
show ureters.
107. • Diameter exceeding 8 mm; asymmetry of ureteral
caliber more significant finding.
• Deviation of ureter.
What to see in ureter:
108.
109.
110.
111.
112. 1)Postero-anterior (prone) abdomen
Projection is to promote emptying of contrast from the
pelvicalyceal system into the ureter.
2)Right or left posterior oblique- this is to show the
relationship of the opacities to the kidneys,
ureters and bladder.
3)Lateral Projection may be used as an alternative
to oblique projection in relative position of
the opacities near to or in the kidneys.
113. Position: Pt. lies prone after doing 15 min full
film and after 4-5 min. of lying prone (so that
lower ureter is dependent part) full film is
taken.
To investigate pelviureteric and ureteric
obstruction as the heavy contrast loaded urine
will more readily gravitate to the site of the
obstruction.
To displace the overlying bowel gas towards
periphery.
114. Can be Considerable upto 24 hours.
In case of :
Significant acute obstruction when early
nephrogram is seen but collecting system is
not seen.
Long standing hydronephrosis
Congenital lesions like non-visualized upper
calyceal system with ectopic or obstructed
ureter.
115. As many films are taken, it is necessary to
perform minimum no. of additional films.
Time interval is generally doubled (and taken
as 0.5, 1, 2, 4, 16, 24 hours
If no opacification of an acutely obstructed
kidney at 30 min it is usually unhelpful to
perform the next film before around 4 h after
contrast injection.
A further manoeuvre to minimise radiation
dose in patients with a strong clinical
suspicion of ureteric colic is to omit all films
after contrast until a full length 15 min film is
performed.
116. CHILDREN
Films at 2 min (supine)
and 7 min (prone) is
taken after contrast
administration.
Or a 2 min (renal area) ,
5 min (renal area),and 15
min full length
abdominal film.
Abdominal compression
not used.
To improve visualization
of left kidney child can
be given a carbonated
beverage.
The right kidney can be
well seen through the
liver in a 15-20 degree
caudal tilted view.
NEONATES
Excretion of contrast
medium is delayed and
prolonged.
The concentration of
contrast medium is
relatively poor.
Optimum visualization of
upper UT may not occur
until 1-3 hour.
If initial 2 min and 5 min
film show little
opacification, further film at
1, 2 and 3 hour may provide
more information than
multiple films in 1st hour.
117. Suspicious shadows in renal areas:
Lateral film of renal area is taken.
Inspiratory and expiratory film of renal area is
taken to demonstrate the relationship of
opacities and filling defects of renal tract.
118. Useful when intermittent obstruction is
suspected but cannot be confirmed by standard
urogram.
I.V. frusemide is used to induce diuresis.
The dose of Lasix/Frusemide is 0.3-1mg/kg in
adults and 0.5mg/kg in child.
The film is taken 5-10 mins after adminstering
the diuretic.
119. Modifies the urogram to provide the information
needed to include or exclude the clinical
problem.
Study is terminated as soon as the desired information
is available.
120. Also called as minute sequence urogram.
Films are taken 1,2,3,5 minutes after injection of
contrast media.
For Renal artery stenosis-
decreased renal size.
delayed appearance of contrast material (decreased glomerular
filtration)
increased density of contrast material (increased water
reabsorption)
delayed washout of contrast material (prolonged urine transit
time)
lack of distension of collecting system
global attenuation of contrast density; urogram may be normal
with adequate collateral circulation
notching of proximal ureter (enlargement of collateral vessels)
121. Small and Smooth kidney
Delayed nephrogram
Delayed and dense pyelogram.
Ureteral notching
122. Disadvantages:
Overload the patient
with more iodine than
necessary.
Calyceal blunting may
be produced suggesting
abnormal dilatation.
May precipitate CCF in
patient with borderline
cardiac complaints.
Initial vascular
nephrogram is not
obtained.
Advantages
• Nephrogram persists for longer
time.
• Enhanced diuresis from the
additional contrast media and water
volume will distend the collecting
system and ureters more clearly.
• Collecting system is visualized for
longer time.
• No significant increase in contrast
reactions.
• Administration is easy.
Contrast is given in 500ml of normal saline.
123. Useful for follow up for earlier pathology
Limited films are taken - KUB , 15mins and post void.
124. Haemodynamically unstable patient destined for
emergency laparotomy a single shot IVU (full
length film 15 min after contrast injection)
may be considered.
125. Due to contrast
Minor reactions- nausea, vomiting, mild rash,
headache, mild dyspnea
Intermediate reactions- Extensive urticaria, facial
edema, bronchospasm, laryngeal edema,
hypotension.
Severe reactions- circulatory collapse, pul edema,
MI, coma, cardiac and respiratory arrest
Due to Technique
Upper arm or shoulder pain.
Extravasation of contrast at injection site
126. Observation for 6 hrs
Watch for late contrast reactions
Prevention of dehydration
In high risk patients – RFT should be done to watch
deterioration.
127. PROTOCOL
Oral water load 0.5-1 l,30-60 min before
Patient supine.
CT kub
LOCM,300 mg I/ml,100 ml bolus IV
1mm slice from diaphragm to lower pole of kidney ,100 sec
following bolus injection for nephrographic phase/parenchymal
phase.
Delayed scan from the upper pole of kidney to bladder base ,20 min
after injection for collecting system and ureter.SPLIT BOLUS
TECHNIQUE
▪ CT UROGRAM
SPLIT BOLUS TECHNIQUE
50 ML OVER 10-15 MIN BEFORE SCAN, 50 ML AT THE TIME OF SCAN
BOTH NEPHROGRAPHIC AND PYELOGRAPHIC PHASE CAN BE SHOWN AT SAME ACQUISITION WITH LOWERING THE
RADIATION DOSE
128. Phases of study:
a. Unenhanced
b. Corticomedullary
c. Nephrographic
d. excretory
129.
130.
131.
132. MAINLY DIVIDED INTO TWO CATEGORIES
1. STATIC MR :-T2 BASED SEQUENCE ,INDEPENDENT OF RENAL
EXCRETORY PROPERTY AS IT USES URIE AS CONTRAST
AGENT,MAINLY FOR DILATED OR OBSTRUCTED COLLECTING
SYSTEM
2. .EXCRETORY MR UROGRAPHY :- T1 BASED POST GADOLINIUM ,
CAN BE DONE WITH NORMAL COLLECTING SYSTEM, USUALLY
POST DIURETIC.GOOD FOR FUNCTION AND MORPHOLOGY
133. ADVANTAGE OF MR UROGRAPHY OVER CT UROGRAPHY
1.ELIMINATION OF IONIZING RADIATION.
2.NON IONIC CONTRAST
3.CONTRAST RESOLUTION
4.NON CONTRAST IMAGING
ADVANTAGES OF CT UROGRAPHY OVER MR UROGRAPHY
1.CLAUSTRO
2.CT:15 MIN, MR:45 MIN
3.SPATIAL RESOLUTION
4.CALCIFICATION NOT SEEN
5.COST
6.UNCOOPERATIVE PATIENTS
134.
135. Indications of IVU
Contrsindications of IVU.
IVU modification in renal artery stenosis
IVU modification in puj obstruction.
Types of contrast and amount in IVU
CT protocol for IVU.