This document outlines the development of a time temperature indicator (TTI) to monitor the temperature history and shelf life of perishable foods. Nearly 3/4 of foodborne illnesses are caused by improper temperature control, so monitoring temperature is important for food safety and quality. Existing TTIs have limitations in cost and complexity. The objectives are to develop a simple, economical TTI that changes color based on temperature exposure. The TTI will be optimized as a label that can be attached to foods. Storage tests will be conducted at various temperatures to measure the TTI response and food quality over time. The color change will be analyzed to determine activation energy and rate constants at different temperatures. This will allow the TTI to monitor real shelf
FoodDrinkEurope: Guía sobre la Gestión de Alérgenos en la industria alimentariaFIAB
This document provides guidance for food manufacturers on managing allergens and food intolerances. It outlines risk management processes including managing people, suppliers, raw materials, equipment, production processes, consumer information, product development and documentation. It also discusses cleaning and validation methods, analytical testing, key allergen management principles and definitions. The annexes provide background on food allergies, allergen risk analysis, labeling requirements, cleaning validation, analytical testing and gluten-free products. The overall aim is to help minimize risk to allergic consumers and ensure they can make informed choices through consistent application of good practices across the European food industry.
The term intelligent involves an ON/OFF switching function on the package in response to changing external/internal stimuli, in order to communicate the product status to its consumers or endusers.The use of features of high added value that enhance the functionality of a product, notably mechanical, electronic and chemical features that improve safety and efficiency.
Este documento describe varias opciones de bachillerato que incluyen bachillerato técnico en asistencia administrativo-contable y electrotecnia, bachillerato general, bachillerato en salud y lácteos y cárnicos. Todos los programas incluyen áreas de formación básica, técnica y complementaria con el objetivo de que los egresados puedan continuar estudios universitarios o desarrollarse en el campo laboral.
Este documento contiene extractos de varias piezas musicales barrocas de compositores italianos como Alessandro Scarlatti, Giovanni Paisiello, Giovanni Battista Bononcini y Giovanni Battista Pergolesi. Los extractos presentan temas como el amor, la naturaleza y las emociones a través de la música y la poesía.
La sociedad secreta de los Iluminati fue fundada en 1776 en Alemania por Adam Weishaupt con el objetivo de abolir los gobiernos nacionales, las religiones excepto el satanismo, la familia, la propiedad privada y el patriotismo, y crear un gobierno mundial controlado por los Iluminati a través de las Naciones Unidas. Actualmente se cree que los Iluminati controlan las grandes corporaciones y los servicios de inteligencia a través de técnicas de control mental.
Catalyst Group's Latest Environment, Health and Safety ProjectSajid Modan, RPh
This document summarizes a case study for a global auditing project conducted by EHS Global Auditing for client Merck. It involved assessing health, safety, and engineering programs across Merck's US and global facilities, with a focus on lock-out tag-out, confined space, and asphyxiant hazard procedures. EHS Global Auditing provided project management, local auditors familiar with regulations, and conducted audits at 27 sites across the US, Europe, Asia, and Brazil, delivering reports and ensuring quality and consistency across locations. The project was completed on time and within budget, providing Merck assurance that its global operations met regulatory standards.
Maratón de Lectura: Read for the Record de Jumpstart
Cuento: Súper Catarina y los Súper Insectos
Fecha: El jueves, 4 de octubre de 2012,
La principal campaña nacional de lectura en Estados Unidos Read for the Record de Jumpstart, en colaboración con la Fundación Pearson reúne millones de personas un día del año para celebrar la alfabetización y respaldar a Jumpstart en sus esfuerzos por promover la educación para la niñez temprana.
Este documento contiene una serie de citas y frases cortas de diferentes autores sobre una variedad de temas como la imaginación, la felicidad, la utopía, la muerte y más. Las citas expresan ideas como que la imaginación es más importante que la lógica, que vivir la vida significa saber para qué se vive, y que la utopía sirve para seguir caminando a pesar de que el horizonte se corra más lejos.
FoodDrinkEurope: Guía sobre la Gestión de Alérgenos en la industria alimentariaFIAB
This document provides guidance for food manufacturers on managing allergens and food intolerances. It outlines risk management processes including managing people, suppliers, raw materials, equipment, production processes, consumer information, product development and documentation. It also discusses cleaning and validation methods, analytical testing, key allergen management principles and definitions. The annexes provide background on food allergies, allergen risk analysis, labeling requirements, cleaning validation, analytical testing and gluten-free products. The overall aim is to help minimize risk to allergic consumers and ensure they can make informed choices through consistent application of good practices across the European food industry.
The term intelligent involves an ON/OFF switching function on the package in response to changing external/internal stimuli, in order to communicate the product status to its consumers or endusers.The use of features of high added value that enhance the functionality of a product, notably mechanical, electronic and chemical features that improve safety and efficiency.
Este documento describe varias opciones de bachillerato que incluyen bachillerato técnico en asistencia administrativo-contable y electrotecnia, bachillerato general, bachillerato en salud y lácteos y cárnicos. Todos los programas incluyen áreas de formación básica, técnica y complementaria con el objetivo de que los egresados puedan continuar estudios universitarios o desarrollarse en el campo laboral.
Este documento contiene extractos de varias piezas musicales barrocas de compositores italianos como Alessandro Scarlatti, Giovanni Paisiello, Giovanni Battista Bononcini y Giovanni Battista Pergolesi. Los extractos presentan temas como el amor, la naturaleza y las emociones a través de la música y la poesía.
La sociedad secreta de los Iluminati fue fundada en 1776 en Alemania por Adam Weishaupt con el objetivo de abolir los gobiernos nacionales, las religiones excepto el satanismo, la familia, la propiedad privada y el patriotismo, y crear un gobierno mundial controlado por los Iluminati a través de las Naciones Unidas. Actualmente se cree que los Iluminati controlan las grandes corporaciones y los servicios de inteligencia a través de técnicas de control mental.
Catalyst Group's Latest Environment, Health and Safety ProjectSajid Modan, RPh
This document summarizes a case study for a global auditing project conducted by EHS Global Auditing for client Merck. It involved assessing health, safety, and engineering programs across Merck's US and global facilities, with a focus on lock-out tag-out, confined space, and asphyxiant hazard procedures. EHS Global Auditing provided project management, local auditors familiar with regulations, and conducted audits at 27 sites across the US, Europe, Asia, and Brazil, delivering reports and ensuring quality and consistency across locations. The project was completed on time and within budget, providing Merck assurance that its global operations met regulatory standards.
Maratón de Lectura: Read for the Record de Jumpstart
Cuento: Súper Catarina y los Súper Insectos
Fecha: El jueves, 4 de octubre de 2012,
La principal campaña nacional de lectura en Estados Unidos Read for the Record de Jumpstart, en colaboración con la Fundación Pearson reúne millones de personas un día del año para celebrar la alfabetización y respaldar a Jumpstart en sus esfuerzos por promover la educación para la niñez temprana.
Este documento contiene una serie de citas y frases cortas de diferentes autores sobre una variedad de temas como la imaginación, la felicidad, la utopía, la muerte y más. Las citas expresan ideas como que la imaginación es más importante que la lógica, que vivir la vida significa saber para qué se vive, y que la utopía sirve para seguir caminando a pesar de que el horizonte se corra más lejos.
This document tracks competitor email newsletter registrations for automotive companies in EU countries. It notes the registration date, positioning/formatting of the registration page, whether a follow up message was received, and frequency of newsletters received from August to December for each manufacturer. Manufacturers include Alfa Romeo, Audi, BMW, Chevrolet, Citroen, Fiat, Ford, Honda and others.
Este documento presenta la hoja de vida de Juan Sebastián Chaparro Correa, incluyendo su nombre, documento de identidad, fecha y lugar de nacimiento, estado civil, ciudad, dirección, teléfono y correo electrónico. Además, detalla sus estudios primarios y secundarios, actualmente cursa el sexto semestre de la universidad y domina el idioma inglés tanto hablado como escrito.
Blue Planet Technologies2010 V03 ShortWESAustralia
Blue Planet Technologies is showcasing a new water cartridge technology that can significantly reduce water wastage from dripping taps. It claims to be able to save up to 60% of water used in homes in Brisbane, Australia, which could supply up to 2.5 homes with the water previously used by one home. The technology is described as innovative, cost effective, energy efficient, and maintenance free, and effectively addresses mineralized water issues. It is presented as an environmentally friendly solution that meets government regulations and is a viable solution to current and future water challenges.
Programa de Dirección en Big Data - IE Business School DEMETRIO BARRAGAN
Big Data – El programa de Dirección del IE Business School es considerado el mejor de su categoría en el ranking entre las mejores escuelas de negocio del mundo.
Entre los aspectos considerados destacan su enfoque estratégico y de creación de valor.
La violencia contra las mujeres incluye violencia física, psicológica y sexual y se define como cualquier conducta o acción basada en una relación desigual de poder que afecte la vida, libertad o integridad de la mujer. La violencia física implica causar dolor o daño al cuerpo de la mujer, mientras que la violencia psicológica causa daño emocional a través de amenazas, acoso u hostigamiento. La violencia sexual se refiere a cualquier acción no consentida que vulnere la autonomía sexual o reproductiva de
Writing a business case or proposal? Need to convince colleagues of the need for change? Want a client to pay on time? These 6 secrets of persuasive writing will help you to craft a message that has the greatest chance of success.
Guatemala ganó los XVII Juegos Centroamericanos Escolares CODICADER, repitiendo así su triunfo por cuarta vez consecutiva. En ajedrez, Guatemala conquistó nueve medallas de oro, incluyendo tres de María Ester Mencos Castillo. Además, el equipo varonil ganó tres medallas de oro. Este triunfo muestra el alto nivel deportivo alcanzado por los estudiantes guatemaltecos.
To eliminate these risks and put IT back in control of the file-sharing process, organizations of all sizes should implement an enterprise-grade file sync and share capability that will meet the dual needs of: a) enabling employees to have access to all of their files from any device, and b) enabling IT to control the organization’s critical data assets.
El documento describe el código ASCII (American Standard Code for Information Interchange), el cual es un estándar de 7 bits que permite 128 combinaciones para representar letras, números, símbolos y caracteres de control. El código ASCII incluye mayúsculas, minúsculas, números, símbolos y 32 caracteres de control divididos en 4 grupos como efectores de formato, control de transmisión, separadores de información y controles de dispositivo.
This report helps analyze and disseminate information on global emerging cities. The report focuses on the demand and supply of talent both lateral and inexperienced/ freshers, availability of cost-effective infrastructure and other factors that make it a feasible and attractive option for organizations looking to expand and grow in this region and remain competitive.
The objective of this research is to conduct in-depth talent pool and location analysis of respected emerging city across identified technology functions which can provide a detailed view of this emerging location and opportunities for growth.
La Play Station 4 es una nueva consola de videojuegos desarrollada por Sony que saldrá a la venta a finales de 2013. La PS4 contará con un procesador de 8 núcleos, 8 GB de RAM, un disco duro integrado y soporte para juegos en la nube. La consola también incluirá un nuevo control con pantalla táctil y funciones enfocadas en compartir contenido y jugar en línea de manera social.
Carlos Prieto es un Director de Consultoría con 18 años de experiencia en proyectos tecnológicos e implantación de soluciones empresariales, especialmente en el área de recursos humanos. Actualmente es el líder nacional de Oracle HCM Cloud en Accenture y ha liderado con éxito varios proyectos innovadores en soluciones SaaS. Tiene una fuerte experiencia funcional y tecnológica en soluciones como SAP, Oracle, PeopleSoft y Success Factors, así como una trayectoria probada en el liderazgo de equipos y la
The document discusses AltaMed's Patient Centered Medical Home (PCMH) model and its Program of All-Inclusive Care for the Elderly (PACE).
AltaMed uses a team-based care coordination approach in its PCMH model, with teams including nurses, health coaches, behavioral health specialists, pharmacists and others supporting primary care providers. For its PACE program, AltaMed provides comprehensive medical and social services to elderly patients to allow them to remain in their communities. Data shows AltaMed's PACE program achieves lower costs, utilization and mortality compared to other models through its integrated care approach.
A deep dive into Bitcoin hardware wallets security. Illustrating weaknesses of hardware wallets based on regular (not secure) microcontrollers such as the Trezor.
El documento resume las actividades realizadas por la Corporación de Contadores de El Salvador durante julio de 2016, incluyendo la clausura de un seminario sobre normas internacionales de información financiera, un curso de gramática y redacción, la apertura de nuevos grupos para diplomados en impuestos y prevención de lavado de dinero, eventos sociales como juramentación de socios y bienvenida a vacaciones, y felicitaciones a socios con cumpleaños en agosto.
O hinduísmo surgiu na Índia no século 3 a.C. e é baseado nos pilares do karma, samsara e dharma. Acredita-se na reencarnação e no sistema de castas dividido em brahmanes, xátrias, vaiáias e xudras. Festivais como o Diwali e o Holi são importantes tradições, e hoje há cerca de 800 milhões de hindus, principalmente na Índia.
- Jungheinrich is a leading intralogistics service and solution provider, ranked #2 in Europe and #3 worldwide.
- In 2015, Jungheinrich saw consolidated net sales of €2.75 billion, an increase of 10.2% over 2014. Net income increased 9.5% to €138 million.
- The global material handling equipment market grew approximately 9% in 2015 to 1.1 million units, driven by growth in Europe and Asia, while North America saw a slight decline. The warehousing equipment segment experienced strong growth globally.
The International Council for Harmonisation (ICH), formerly the International Conference on Harmonisation (ICH) held the inaugural Assembly meetings on 23 October 2015 establishing ICH as an international association, a legal entity under Swiss law.
This step built upon a 25-year track record of successful delivery of harmonised guidelines for global pharmaceutical development as well as their regulation, and a longer standing recognition of the need to harmonise.The guidance stated in the ICH harmonized tripartite guideline entitled “Stability Testing of New Drug Substances and Products” (issued by ICH on October 27, 1993) applies in general to biotechnological/biological products.
The document discusses food quality changes during distribution from farm to fork. It focuses on quantifying color change and developing a mathematical model for color change over time of frozen beans stored at different temperatures. The methodology measures color, texture, and ascorbic acid content of raw and blanched beans stored at -10C, -5C and 4C. Results show all quality indices depend on storage time and temperature, with ascorbic acid potentially limiting quality at lower temperatures. A temperature survey of retail freezers showed variability requiring models to estimate quality during variable temperature distribution. Future work proposes determining important consumer traits, an ERP system to calculate shelf-life, and applying quality index methods used for fish to beans.
This document tracks competitor email newsletter registrations for automotive companies in EU countries. It notes the registration date, positioning/formatting of the registration page, whether a follow up message was received, and frequency of newsletters received from August to December for each manufacturer. Manufacturers include Alfa Romeo, Audi, BMW, Chevrolet, Citroen, Fiat, Ford, Honda and others.
Este documento presenta la hoja de vida de Juan Sebastián Chaparro Correa, incluyendo su nombre, documento de identidad, fecha y lugar de nacimiento, estado civil, ciudad, dirección, teléfono y correo electrónico. Además, detalla sus estudios primarios y secundarios, actualmente cursa el sexto semestre de la universidad y domina el idioma inglés tanto hablado como escrito.
Blue Planet Technologies2010 V03 ShortWESAustralia
Blue Planet Technologies is showcasing a new water cartridge technology that can significantly reduce water wastage from dripping taps. It claims to be able to save up to 60% of water used in homes in Brisbane, Australia, which could supply up to 2.5 homes with the water previously used by one home. The technology is described as innovative, cost effective, energy efficient, and maintenance free, and effectively addresses mineralized water issues. It is presented as an environmentally friendly solution that meets government regulations and is a viable solution to current and future water challenges.
Programa de Dirección en Big Data - IE Business School DEMETRIO BARRAGAN
Big Data – El programa de Dirección del IE Business School es considerado el mejor de su categoría en el ranking entre las mejores escuelas de negocio del mundo.
Entre los aspectos considerados destacan su enfoque estratégico y de creación de valor.
La violencia contra las mujeres incluye violencia física, psicológica y sexual y se define como cualquier conducta o acción basada en una relación desigual de poder que afecte la vida, libertad o integridad de la mujer. La violencia física implica causar dolor o daño al cuerpo de la mujer, mientras que la violencia psicológica causa daño emocional a través de amenazas, acoso u hostigamiento. La violencia sexual se refiere a cualquier acción no consentida que vulnere la autonomía sexual o reproductiva de
Writing a business case or proposal? Need to convince colleagues of the need for change? Want a client to pay on time? These 6 secrets of persuasive writing will help you to craft a message that has the greatest chance of success.
Guatemala ganó los XVII Juegos Centroamericanos Escolares CODICADER, repitiendo así su triunfo por cuarta vez consecutiva. En ajedrez, Guatemala conquistó nueve medallas de oro, incluyendo tres de María Ester Mencos Castillo. Además, el equipo varonil ganó tres medallas de oro. Este triunfo muestra el alto nivel deportivo alcanzado por los estudiantes guatemaltecos.
To eliminate these risks and put IT back in control of the file-sharing process, organizations of all sizes should implement an enterprise-grade file sync and share capability that will meet the dual needs of: a) enabling employees to have access to all of their files from any device, and b) enabling IT to control the organization’s critical data assets.
El documento describe el código ASCII (American Standard Code for Information Interchange), el cual es un estándar de 7 bits que permite 128 combinaciones para representar letras, números, símbolos y caracteres de control. El código ASCII incluye mayúsculas, minúsculas, números, símbolos y 32 caracteres de control divididos en 4 grupos como efectores de formato, control de transmisión, separadores de información y controles de dispositivo.
This report helps analyze and disseminate information on global emerging cities. The report focuses on the demand and supply of talent both lateral and inexperienced/ freshers, availability of cost-effective infrastructure and other factors that make it a feasible and attractive option for organizations looking to expand and grow in this region and remain competitive.
The objective of this research is to conduct in-depth talent pool and location analysis of respected emerging city across identified technology functions which can provide a detailed view of this emerging location and opportunities for growth.
La Play Station 4 es una nueva consola de videojuegos desarrollada por Sony que saldrá a la venta a finales de 2013. La PS4 contará con un procesador de 8 núcleos, 8 GB de RAM, un disco duro integrado y soporte para juegos en la nube. La consola también incluirá un nuevo control con pantalla táctil y funciones enfocadas en compartir contenido y jugar en línea de manera social.
Carlos Prieto es un Director de Consultoría con 18 años de experiencia en proyectos tecnológicos e implantación de soluciones empresariales, especialmente en el área de recursos humanos. Actualmente es el líder nacional de Oracle HCM Cloud en Accenture y ha liderado con éxito varios proyectos innovadores en soluciones SaaS. Tiene una fuerte experiencia funcional y tecnológica en soluciones como SAP, Oracle, PeopleSoft y Success Factors, así como una trayectoria probada en el liderazgo de equipos y la
The document discusses AltaMed's Patient Centered Medical Home (PCMH) model and its Program of All-Inclusive Care for the Elderly (PACE).
AltaMed uses a team-based care coordination approach in its PCMH model, with teams including nurses, health coaches, behavioral health specialists, pharmacists and others supporting primary care providers. For its PACE program, AltaMed provides comprehensive medical and social services to elderly patients to allow them to remain in their communities. Data shows AltaMed's PACE program achieves lower costs, utilization and mortality compared to other models through its integrated care approach.
A deep dive into Bitcoin hardware wallets security. Illustrating weaknesses of hardware wallets based on regular (not secure) microcontrollers such as the Trezor.
El documento resume las actividades realizadas por la Corporación de Contadores de El Salvador durante julio de 2016, incluyendo la clausura de un seminario sobre normas internacionales de información financiera, un curso de gramática y redacción, la apertura de nuevos grupos para diplomados en impuestos y prevención de lavado de dinero, eventos sociales como juramentación de socios y bienvenida a vacaciones, y felicitaciones a socios con cumpleaños en agosto.
O hinduísmo surgiu na Índia no século 3 a.C. e é baseado nos pilares do karma, samsara e dharma. Acredita-se na reencarnação e no sistema de castas dividido em brahmanes, xátrias, vaiáias e xudras. Festivais como o Diwali e o Holi são importantes tradições, e hoje há cerca de 800 milhões de hindus, principalmente na Índia.
- Jungheinrich is a leading intralogistics service and solution provider, ranked #2 in Europe and #3 worldwide.
- In 2015, Jungheinrich saw consolidated net sales of €2.75 billion, an increase of 10.2% over 2014. Net income increased 9.5% to €138 million.
- The global material handling equipment market grew approximately 9% in 2015 to 1.1 million units, driven by growth in Europe and Asia, while North America saw a slight decline. The warehousing equipment segment experienced strong growth globally.
The International Council for Harmonisation (ICH), formerly the International Conference on Harmonisation (ICH) held the inaugural Assembly meetings on 23 October 2015 establishing ICH as an international association, a legal entity under Swiss law.
This step built upon a 25-year track record of successful delivery of harmonised guidelines for global pharmaceutical development as well as their regulation, and a longer standing recognition of the need to harmonise.The guidance stated in the ICH harmonized tripartite guideline entitled “Stability Testing of New Drug Substances and Products” (issued by ICH on October 27, 1993) applies in general to biotechnological/biological products.
The document discusses food quality changes during distribution from farm to fork. It focuses on quantifying color change and developing a mathematical model for color change over time of frozen beans stored at different temperatures. The methodology measures color, texture, and ascorbic acid content of raw and blanched beans stored at -10C, -5C and 4C. Results show all quality indices depend on storage time and temperature, with ascorbic acid potentially limiting quality at lower temperatures. A temperature survey of retail freezers showed variability requiring models to estimate quality during variable temperature distribution. Future work proposes determining important consumer traits, an ERP system to calculate shelf-life, and applying quality index methods used for fish to beans.
Institution of Prosecution against the Act of Transporting In a Vehicle a Bul...Agriculture Journal IJOEAR
—Storage temperature plays a major role in causing changes in quality and safety of poultry meat. Product should retain its desired sensory, chemical, physical, functional and microbiological characteristics. Authorized Officers are expected to guide and inspect on food safety and security measures of the country. After conducting comprehensive food outlet inspections covering the whole Medical Officer Health (MOH) area and legal prosecutions over violation of law related to food safety, inspections of food transporting vehicles were conducted. Twenty vehicles were inspected and 7 out of them were released after giving strict advice, 3 were detained to produce before courts. By entering a plea of guilty, first two defendants were admitting their guilt and fined 67 USD each. Last case was charged against the chicken company transporting chicken at temperature of +5 0 Centigrade (standard-18 0 Centigrade), where company lawyer admitted a plea of guilt, but pleaded to release all chicken worth of 2700 USD. Usually in Sri Lankan context, temperature of container was measuring by thermometers as a spot reading of whole passage of cold chain of frozen foods. Upon the expert opinion and scientific explaining by the MOH of the impact of releasing this bulk of chicken on the health of the general public, the Magistrate made decision against the company with strict advice to maintain all vehicles in good sanitary condition, fined 67 USD and ordered to destroy the entire bulk quantity of chicken worth 2000 USD under the supervision of the MOH. This would set future reference/ benchmark in field of food safety in Sri Lanka to supervise and examine of temperature record by Authorized officers using smart phones on data lodgers, which records should be maintained by all frozen food companies thorough out their cold chain, and it can be used as weighted and firm evidence for their legal submissions in future as a complete reflection of cold chain. Keywords— Shelf life, food safety, enactment of food act, poultry meat, unhygienic transport, public health legislation.
Heat Treatment of Foods: New Developments and Trends”
Parma 25 June 1999
APPLICATION, LIMIT AND POTENTIALITY
OF HTST TREATMENT
Roberto Massini
Institute of Food Production and Processing, University of Bari, Italy
High Temperature Short Time heat treatment, HTST affects production costs, HTST to optimise thermal effects, Ambiguity of thermal effects, HTST to improve food quality, Temperature dependance of reaction rates in foods, Variability of microbial heat resistance,HTST process control
The document contains a written exam for Steve Brandon containing 8 questions about food science. Question 1 asks him to describe the 5 most important food science discoveries in the past 50 years and choose one to discuss in more detail. It then asks for an experimental design to continue research in that area. Question 2 asks him to discuss 3 food preservation processes and provide details of each. The exam continues with questions about evaporation, psychrotrophic bacteria, food pathogens, membrane filtration processes and applications of dissertation research.
This document discusses heat treatments used in food processing. It begins by defining heat treatment and describing its objectives. It then explains various heat treatment methods like cooking, blanching, pasteurization, and sterilization. Cooking can be done through immersion, extrusion, or other systems. Blanching aims to clean products, inactivate enzymes, and reduce microbes. Pasteurization and sterilization both involve applying heat to food but to different degrees, with sterilization using higher temperatures to eliminate all microorganisms. The document also covers heat transfer mechanisms and how treatment times depend on factors like food properties and temperature. It analyzes the effects of heat treatments on nutrients and quality.
Stability studies are conducted to prove how the quality of a drug substance or product varies over time under different environmental conditions like temperature, humidity, and light. The purpose is to determine the shelf life and appropriate storage conditions. Key factors that can affect stability include active ingredient properties, interactions, manufacturing process, dosage form, container, and storage conditions during transport and handling. Studies are done under long term, accelerated, and intermediate conditions following protocols to collect data at various time points and interpret results to establish expiration dates.
Food Processing and preservation 3 - Sterilization.pdfPeterJofilisi
The document discusses food sterilization and preservation through heat processing. It describes sterilization as using high heat to destroy microbes and enzymes, giving foods a shelf life over 6 months. The factors that influence sterilization time include heat resistance of microbes, heating conditions, food acidity, and container size. Proper sterilization requires knowledge of microbe concentrations and heat resistance. Microbe death through heat follows a logarithmic order and can be measured using D-values and Z-values. Different container types and the rate of heat penetration must also be considered for effective sterilization.
Food Processing and preservation 3 - Sterilization.pdfPeterJofilisi
The document discusses food sterilization and preservation through heat processing. It describes sterilization as using high heat to destroy microbes and enzymes, giving foods a shelf life over 6 months. The factors that influence sterilization time include heat resistance of microbes, heating conditions, food acidity, and container size. Proper sterilization requires knowledge of microbe concentrations and heat resistance. Microbe death through heat follows a logarithmic order and can be measured using D-values and Z-values. Different container types and the rate of heat penetration must also be considered for effective sterilization.
Evaluation of the efficiency of sterilization methods.Sterility indicatorsMs. Pooja Bhandare
Evaluation of the efficiency of sterilization methods.Sterility indicators
Sterility criteria: Bioburden ,Sensitivity of microorganisms
Death rate or Survivor curve,D- Value or Decimal reduction time,Z- value or Thermal reduction time, f- value, Q10 Value or Temperature Coefficient, Inactivation Factor:
STERILITY INDICATORS : Physical Indicators, Chemical Indicators
Biological Indicators
1. Physical Indicators: i) Moist heat Indicator ii) Dry heat iii) Radio sterilization iv) Gaseous methods v) Filtration 2.CHEMICAL INDICATORS : I) Browne’s tubes II) WITTNESS TUBES IV) Royce Sachet V) Chemical Dosimeter 3.BIOLOGICAL INDICATORS
This document summarizes a study that evaluated mitochondrial DNA (mtDNA) fragmentation as a potential time-temperature integrator for monitoring safety and quality in dry roasted peanuts. MtDNA fragmentation was measured using quantitative PCR (qPCR) and compared to reduction of the Salmonella surrogate Enterococcus faecium and changes in peanut color (Hunter L value) during roasting. While E. faecium reduction curves were highly repeatable, mtDNA fragmentation did not correlate linearly with time at a given temperature. Dissection of individual peanuts also showed differential heating effects depending on peanut part. The researchers determined that mtDNA fragmentation as measured by qPCR was too variable for validation of dry roasted peanut processes but could help evaluate heat penetration through
This document discusses food preservation through the use of combined or hurdle methods. Some key points:
- Combined preservation methods use multiple preservation factors (called hurdles), which together inhibit microbial growth through additive or synergistic effects. This allows for gentler processing that maintains sensory and nutritional properties.
- Important hurdles include water activity, pH, redox potential, preservatives, and competitive microflora. Shelf-stable products (SSPs) rely on mild heat combined with reduction of one or more hurdles like water activity or pH to prevent microbial spoilage without refrigeration.
- The concept of hurdle technology involves intelligently combining hurdles to ensure microbial stability as well
Presentation on-stability-study of pharmaceutical productMd Mohsin
this content takes important information about stability & stability study of pharmaceutical products including guidelines,climate zone,testing conditions,sampling plan,extension of shelf life,re test,current trends in stability study etc.
Effect of temperature, time, and material thickness on the dehydration proces...fstdesk.com
This research article studied the effect of temperature, time, and thickness on the dehydration process of tomatoes. Experiments were conducted drying tomato slices at different temperatures and times. Mathematical models were developed to predict mass loss during drying based on temperature and time. The optimal drying conditions were found to be 60°C, with the lowest thickness level, and shorter drying time, in order to avoid losses and maintain product quality during dehydration.
This study evaluated different sanitation methods on the quality of fresh cherry and plum salad over 10 days of storage at 4°C. The fruit was minimally processed and packaged under modified atmosphere. Using UV-C radiation and 10g/L ascorbic acid (Treatment 2) was most effective in reducing microbial growth, maintaining antioxidant compounds and sensory quality compared to water (Control) or ascorbic acid alone. Treatment 2 reduced mesophilic bacteria by 1.15 log CFU/g and psychrotrophic bacteria by 1 log CFU/g versus the Control after 10 days. It also better preserved color, phenolic content, anthocyanins and antioxidant activity over time. This combinated treatment shows potential as an environment
JFS#2 final before print 10-9-15 jfds13139_Rev (1)Jane Caldwell
Mitochondrial DNA (mtDNA) fragmentation was assessed in acidified foods using quantitative PCR (qPCR). Ct values from cucumber mtDNA at different processing stages and storage times were significantly different, indicating mtDNA fragmentation from low temperature (75C for 15 min) processing in acidic conditions (pH 3.8). Pasteurization of tomato serum at 95C for varying times highly correlated Ct values to time-temperature treatment. Longer qPCR amplicons provided greater sensitivity to differentiate heat treatments. MtDNA fragmentation is a potential tool to characterize low temperature (<100C) high acid processes, fermentations, and storage of acidic plant products.
This document discusses a study that examined the correlation between hue angle and color lightness (L*) of fresh and dried mushrooms that were gamma irradiated at different doses and stored for various time periods. The study found good linear correlations between hue angle and lightness for both fresh mushrooms (r2 =0.54 and r2 = 0.657) and dried mushrooms (r2 = 0.74 and r2 = 0.624). This correlation indicates that monitoring only the lightness parameter could provide information about color changes after treatments like gamma irradiation and storage. The linearity between lightness and hue was strongest for dried mushrooms that were irradiated prior to storage.
Effect of early age thermal challenge on growth performance, haematological p...Innspub Net
This study aimed to evaluate the effect of thermal stress on haematological profile and carcass yield of guinea fowl (GF). A total of 180 one-day old GF keets were assigned to 3 treatments, having 4 replicates of 15 birds each. The treatments were: control (T1); mild heat stress for 6h/day (T2), and high heat stress for 8h/day (T3). Data were collected on weekly body weights, feed intake and feed conversion ratio of the birds. At 6-weeks old, blood samples were collected from 8 GF for determination of haematological profile. At 14-weeks old, 8 birds were also slaughtered per treatment to evaluate relative organ weights, carcass characteristics and immune response. Results showed that the body weight gain and feed intake of the birds of T1 and T2 were similar and significantly higher than that of T3 at week 1 of age. The FCR of the birds in T1 and T2 were also better at this stage. Lymphocyte counts were higher (p<0.01) in the birds of T2 (95 103/mL) than those of the control (93.33 103/mL) and T3 (93.33 103/mL). The weights of lymphoid organs of T2 and T3 birds were higher (p<0.05) than those of the control group. It was concluded that exposure of keets to heat stress for 8h/day had adverse effects on growth performance at the early age but this effect faded with age. The thermal manipulation in this study didn’t influence the carcass yield but improved the weights of lymphoid organs of indigenous GF, indicating a better thermo-tolerance.
A heat exchanger is a device that transfers thermal energy between fluids or between fluids and solids without mixing the substances. Heat exchangers have various applications including heating, cooling, and phase changing of fluids. In most heat exchangers, a separating wall prevents direct contact between the fluids and facilitates heat transfer through conduction. Sterilization is the process of eliminating microorganisms through physical, chemical, or other means and is important in pharmaceutical applications to prevent contamination of medical products and equipment. Several factors influence sterilization effectiveness including temperature, time, the type of microorganism, and presence of organic material.
1. Development of a Time temperature indicator to monitor the real
shelf life of perishable food products for consumer’s safety and
awareness
Outline of the problem:
Expectation of customers towards foods with improved sensory quality, increased
nutritional properties and extended shelf life has led to various improvements in packaging of the
processed food products. Nearly ¾ of all food related illness are the result of poor temperature
control. The temperature variations in a food product can lead to changes in product quality and
safety. Since temperature determines the storage parameter of a processed food product,
therefore monitoring and controlling of temperature is of great importance as it is directly related
to the safety and quality aspects of the food. Consumption of spoiled foods will apparently lead
to a lot of health consequences. Perishables deteriorate in relatively short period of time. For
every 10°C increase above the optimum temperature, the shelf-life of delicate fruit and
vegetables is halved. Optimum temperature range for the growth of pathogens is from 5°C to
57°C. This range is called as danger zone. So, in order for a food to be free from spoilage, it must
be maintained below 4°C. Prolonged exposure to extreme or elevated temperature can force
ripening of fruit, cause dangerous spoilage of foods such as seafood. In some condition, such as
heating pre-prepared food, it is essential to know that a critical temperature has been exceeded.
Besides the microbial growth and possible food borne illness, the high temperature (above 21°C)
accelerates physical changes and chemical reactions promoting deterioration on foods (Karel,
1984). Gregory (1996) reported that vitamins and aroma are affected under temperature above 50
°C and luminosity conditions during storage, transport and commercialization.
An intelligent package is one that can monitor the quality and safety condition of a food
product and provide early warning to the consumer or food manufacturer. Moreover, customer
security assurance is of primary importance. Normally the safety of a chilled ready to eat food is
answered by “Best by” date in the labeling. But that does not explain whether the food product
has been exposed to elevated temperature during storage or transportation. This can be monitored
using a Time Temperature Indicator (TTI).
2. Current Status:
The applicability of TTIs has been evaluated for various perishable foods including
chilled fish (Tinker et al., 1985; Taoukis et al., 1999), dairy products (Chen and Zall, 1987;
Grisius et al., 1987; Shellhammer and Singh, 1991), meat and poultry (Labuza and Fu, 1995),
frozen fruit and vegetables (Singh and Wells, 1987; Giannakourou and Taoukis, 2002), frozen
meats (Rodriguez and Zaritzki, 1983; Singh and Wells, 1985; Yoon et al., 1994), and to estimate
the remaining shelf life of food products (Fu, Petros, & Theodore, 1999; Rice, 1989; Sherlock,
Fu, & Taoukis, 1991; Taoukis and Labuza, 1989; Taoukis et al., 1999; Taoukis, 2001), A TTI
developed based on a fadable ink, which disappear in a defined time period (Galagan., Y, 2008).
An amylase type time temperature indicator was developed based on the reaction between starch
and amylase (Sun Yan, 2008)
Based on the mechanism, there are three different types of TTIs are commercially
available. (1) Polymerization - Fresh-Check®
by LifeLines Technology, Inc. is based on
polymerisation reaction of diacetylenic monomers. As polymerisation takes place, the colour of a
‘‘bulls-eye’’ patterned indicator changes gradually. (2) Enzymatic or chemical reaction -
Checkpoint®
developed by Vitsab, based on an enzymatic reaction causing pH-change in the
reaction mixture, is activated by breaking the seal between a solution containing lipolytic
enzyme and its lipid substrate. The reaction is visualised with a pH dye included in the system,
the colour of the dye is changed from green to yellow as the pH changes during the reaction. (3)
Diffusion - 3M MonitorMark®
USA, has launched a TTI which is diffusion based indicator label
and is on the color change of an oxidable chemical system controlled by temperature-dependent
permeation through a film. The process is activated by a blue-dyed fatty acid ester diffusing
along a wick. A viscoelastic material migrates into a diffusely light reflective porous matrix at a
temperature dependent rate. MonitorMark has two versions of TTI, one for monitoring
distribution, for industrial use and other, providing consumer information, the smart label
(Kuswandi et al., 2011). Timestrips® (Timestrip UK Limited, UK are smart labels for monitor
how long a product has been open or how long it has been in use. The label is automatically
activated when the consumer opens the packaging or it can be supplied as an external label that
consumers can manually activate when they first use a product (Selman, 1995; Kuswandi et al.,
2011). (eO)® TTI, is based on a time-temperature depended pH change caused by controlled
microbial growth selected strains of lactic acid bacteria that is expressed to colour change
3. through suitable pH indicators. Once they attached to the food, in case of temperature
fluctuation, or when the product reaches its use by date, the temperature-dependent growth of the
TTI microorganisms causes a pH drop in the tags leading to an irreversible color change of the
indicator which becomes red (Ellouze et al., 2008; Taoukis, 2008).
Although, lot of literature available on TTI based on various mechanisms, cost and
complexity of the device makes it difficult for practical application. This work focuses on
development of an economical, efficient and simple TTI, based on chemical reaction that can
have large application in the market.
Importance of the work:
The role of temperature on the spoilage rate in foods, as it is for any chemical reaction, is
well known. The temperature not only affects the rate of spoilage reactions, which involve both
bacterial and autolytic enzymes, but it also affects the rate at which bacteria multiply. For
example, generation time for Pseudomonas fragi, a common fish-spoilage bacterium, is about 12
hours at 32°F; it is only about 2 hours at 55°F (Duncan and Nickerson 1961). Storage
temperature can also influence which type of disease develops. For example in potatoes the fungi
that causes dry rot can grow rapidly at lower temperatures (15 -25°C) whereas the bacteria that
cause the soft smelly rot, only grows rapidly at warmer temperatures (> 25°C).Thus, Storage
temperature is very important to guarantee microbial quality and safety of perishable foods.
Temperature fluctuation during storage and distribution of food will lead to spoilage of food and
thus by reduction in shelf life and quality of the food product. Consumption of spoiled food
product leads to various health hazardous like Stomach cramps, Fever, Headache, Nausea,
Vomiting, Diarrhea and may also result in fatal end. So it is essential to understand and educate
customers about the time temperature history of the food product. This can be achieved by
attaching a TTI on the external surface of the food product, which will undergo colour change
with varying temperature to which the food is being subjected.
4. Objectives:
To develop a Time temperature indicator (TTI) that changes colour with respect to the
change in temperature of food product, thus by understanding the temperature history of
the food product for food safety.
To optimize TTI for few selected perishable food product.
To monitor the real shelf life of a perishable food product using TTI.
Technical Program:
Designing of TTI:
TTI can be optimized into a label form that can be attached externally on the food
product to monitor the time temperature history of the product. Label can be designed in such a
way that it contains two compartments. These two compartments can be separated by a physical
barrier to avoid contact between activator and the gel matrix. Removing physically the barrier
between two compartments will results in activation of the TTI and helps to monitor the time
temperature history of the food product to which it is being attached.
TTI response:
To identify the TTI response, storage experiments to be conducted at the same isothermal
and non-isothermal conditions as those applied for the perishable food product. For six different
temperature profiles the continuous colour change of the reaction window of TTIs will be
measured instrumentally at regular time intervals using a colour measuring instrument until the
end point colour will be reached.
Change in colour of TTI:
5. The change in colour of TTI will be measured using a colour analyzer. The L*, a*, b*
chroma system, which uses the corresponding value of total color difference (∆E) as dynamic
parameters, will be used to analyze the dynamic change in the indicator’s color. According to the
indicator kinetics characterized by Taoukis and Labuza (1989), the total color difference value X
= ∆E of the indicator could be expressed in terms of a response function as follows:
F(X) = kt
Where, k stands for the rate constant of the reaction that is correlated with temperature, and t
stands for the storage time. By plotting a curve between the response function of total color
difference F(X) and time, a straight line could be obtained, and the k of different storage
temperatures could be calculated from the slope. Taking the logarithm on both sides of the
Arrhenius function:
lg k = lg A
By plotting a curve between lg k and 1/T, a straight line will be obtained. The activation energy
could be calculated from the slope, and A from the intercept directly.
Storage Tests:
The sets of TTI and food products will be stored at various temperatures using incubators.
The samples will be periodically taken to measure the TTI response and food during regular
intervals. All samples will be analysed in triplicates.
Determination of microbiological quality:
The growth of total aerobic bacteria and psychrotrophic bacteria in the selected food
product will be measured at five constant temperatures: 2, 5, 7, 12, and 15°C. Samples will be
drawn at predetermined intervals according to the storage temperature conditions. The lag times
will be determined graphically and the growth rate constant will be calculated through linear of
the exponential phase of the growth curve.
6. Samples of food product will be aseptically weighed, added to 1/4 strength Ringer's
solution, and will be homogenized in a stomacher for 60 seconds at room temperature. Decimal
serial dilutions in quarter strength Ringer's solution will be prepared and duplicate 1 ml or 0.1 ml
samples of appropriate dilutions will be poured or spread on the surface of the appropriate media
in petri dishes for enumeration of Total viable count (TVC). All plates will be examined visually
for typical colony types and morphological characteristics that were associated with each growth
medium.
Sensory Evaluation:
The typical sensory analysis for selected food product will be followed during the storage
experiments at different temperatures. The evaluation will be performed by a trained sensory
panel (8–10 people) using QDA on 15 point scale (Stone, H. & Sidel, 1993). The sensory
qualities will be judged under fluorescent light in a booth room with individual boxes, rating
from 1 (excellent fresh) to 10 (extremely deteriorated). The cut-off score was fixed at 7.5. The
sample will be considered as unacceptable when a mean score above five is reached.
Calibration curves of TTI response vs. quality changes:
TTI is an indicator to show the food quality changes during storage or distribution. So
there should be a fixed relationship between TTI response and food qualities, otherwise TTI
would not be a reliable indicator. The data points of TTI response could directly be correlated
with those of the food qualities by eliminating the storage time, a common independent variable,
from both relationships. The lines will be estimated by using the kinetic equations for TTI
response and food product quality.
7. Year-wise plan of work:
First year:
1. Development of time temperature indicator using various pH indicators.
2. Optimization of the pH dyes for the development of TTI
3. Optimizing parameters of TTI for specific perishable food products.
Second Year:
1. Designing of TTI into a label form
2. Application of the indicator with perishable food products and accessing their shelf
life.
Third Year:
1. Studies on relationship between the color change of TTI and quality characteristics of
the food product.
2. Presentation of the work in conferences.
3. PhD thesis preparation
8. References
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